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Found 13 with Last Name = 'huang' and Initial = 'kf'
TargetGlutaminyl-peptide cyclotransferase(Homo sapiens (Human))
Academia Sinica

LigandPNGBDBM7918(1-(3,4-dimethoxyphenyl)-3-[3-(1H-imidazol-1-yl)pro...)
Affinity DataKi:  95nM ΔG°:  -40.1kJ/molepH: 8.0 T: 2°CAssay Description:The testing for the inhibition activities of imidazole derivatives and cacodylate on gQC and sQC was evaluated at 25 C using the fluorescent substrat...More data for this Ligand-Target Pair
TargetGlutaminyl-peptide cyclotransferase(Homo sapiens (Human))
Academia Sinica

LigandPNGBDBM7887(1-Benzylimidazole (BI) | 1-benzyl-1H-imidazole | 1...)
Affinity DataKi:  262nM ΔG°:  -37.6kJ/molepH: 8.0 T: 2°CAssay Description:The testing for the inhibition activities of imidazole derivatives and cacodylate on gQC and sQC was evaluated at 25 C using the fluorescent substrat...More data for this Ligand-Target Pair
TargetGlutaminyl-peptide cyclotransferase(Homo sapiens (Human))
Academia Sinica

LigandPNGBDBM7887(1-Benzylimidazole (BI) | 1-benzyl-1H-imidazole | 1...)
Affinity DataKi:  607nM ΔG°:  -35.5kJ/molepH: 8.0 T: 2°CAssay Description:The testing for the inhibition activities of imidazole derivatives and cacodylate on gQC and sQC was evaluated at 25 C using the fluorescent substrat...More data for this Ligand-Target Pair
TargetGlutaminyl-peptide cyclotransferase(Homo sapiens (Human))
Academia Sinica

LigandPNGBDBM7949(Imidazole C-4(5) deriv. 1 | N-[2-(1H-Imidazol-4-yl...)
Affinity DataKi:  1.70E+3nM ΔG°:  -32.9kJ/molepH: 8.0 T: 2°CAssay Description:The testing for the inhibition activities of imidazole derivatives and cacodylate on gQC and sQC was evaluated at 25 C using the fluorescent substrat...More data for this Ligand-Target Pair
TargetGlutaminyl-peptide cyclotransferase(Homo sapiens (Human))
Academia Sinica

LigandPNGBDBM7918(1-(3,4-dimethoxyphenyl)-3-[3-(1H-imidazol-1-yl)pro...)
Affinity DataKi:  1.82E+3nM ΔG°:  -32.8kJ/molepH: 8.0 T: 2°CAssay Description:The testing for the inhibition activities of imidazole derivatives and cacodylate on gQC and sQC was evaluated at 25 C using the fluorescent substrat...More data for this Ligand-Target Pair
TargetGlutaminyl-peptide cyclotransferase(Homo sapiens (Human))
Academia Sinica

LigandPNGBDBM7949(Imidazole C-4(5) deriv. 1 | N-[2-(1H-Imidazol-4-yl...)
Affinity DataKi:  5.75E+3nM ΔG°:  -29.9kJ/molepH: 8.0 T: 2°CAssay Description:The testing for the inhibition activities of imidazole derivatives and cacodylate on gQC and sQC was evaluated at 25 C using the fluorescent substrat...More data for this Ligand-Target Pair
TargetGlutaminyl-peptide cyclotransferase(Homo sapiens (Human))
Academia Sinica

LigandPNGBDBM92451(Cacodylate)
Affinity DataKi:  1.82E+6nM ΔG°:  -15.6kJ/molepH: 8.0 T: 2°CAssay Description:The testing for the inhibition activities of imidazole derivatives and cacodylate on gQC and sQC was evaluated at 25 C using the fluorescent substrat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutaminyl-peptide cyclotransferase(Homo sapiens (Human))
Academia Sinica

LigandPNGBDBM92451(Cacodylate)
Affinity DataKi:  6.70E+6nM ΔG°:  -12.4kJ/molepH: 8.0 T: 2°CAssay Description:The testing for the inhibition activities of imidazole derivatives and cacodylate on gQC and sQC was evaluated at 25 C using the fluorescent substrat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
National Defense Medical Center

Curated by ChEMBL
LigandPNGBDBM50428824(CHEMBL2336662)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of TERT activity in human H1299 cells homogenates incubated for 5 mins by TRAP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
National Defense Medical Center

Curated by ChEMBL
LigandPNGBDBM50068320(2,7-Bis[3-(pyrrolidino)propionamido]anthraquinone ...)
Affinity DataIC50:  6.70E+3nMAssay Description:Inhibition of G-quadruplex-induced human TERT in H1299 cells by TRAP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
National Defense Medical Center

Curated by ChEMBL
LigandPNGBDBM50068321(2,7-Bis[3-(piperidino)propionamido]anthraquinone |...)
Affinity DataIC50:  8.40E+3nMAssay Description:Inhibition of G-quadruplex-induced human TERT in H1299 cells by TRAP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
National Defense Medical Center

Curated by ChEMBL
LigandPNGBDBM50428822(CHEMBL2336667)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of TERT activity in human H1299 cells homogenates incubated for 5 mins by TRAP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
National Defense Medical Center

Curated by ChEMBL
LigandPNGBDBM50428823(CHEMBL2336666 | NSC-749235)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of TERT activity in human H1299 cells homogenates incubated for 5 mins by TRAP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed