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Found 55 with Last Name = 'hudyma' and Initial = 't'
TargetRNA-directed RNA polymerase(Hepacivirus C)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50484982(CHEMBL2017865)
Affinity DataIC50: >600nMAssay Description:Inhibition of Hepatitis C virus NS5B RNA-dependent RNA polymerase P495L mutantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepacivirus C)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50484986(CHEMBL2017863)
Affinity DataIC50:  1.73E+3nMAssay Description:Inhibition of Hepatitis C virus NS5B RNA-dependent RNA polymerase P495L mutantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepacivirus C)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50484981(CHEMBL2017862)
Affinity DataIC50:  2.28E+3nMAssay Description:Inhibition of Hepatitis C virus NS5B RNA-dependent RNA polymerase P495L mutantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepacivirus C)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50484983(CHEMBL2017866)
Affinity DataIC50:  2.80E+3nMAssay Description:Inhibition of Hepatitis C virus NS5B RNA-dependent RNA polymerase P495L mutantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepacivirus C)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50484985(CHEMBL2017864)
Affinity DataIC50:  3.10E+3nMAssay Description:Inhibition of Hepatitis C virus NS5B RNA-dependent RNA polymerase P495L mutantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepacivirus C)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50484977(CHEMBL2017856)
Affinity DataIC50:  3.39E+3nMAssay Description:Inhibition of Hepatitis C virus NS5B RNA-dependent RNA polymerase P495L mutantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepacivirus C)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50484984(CHEMBL2017858)
Affinity DataIC50:  3.72E+3nMAssay Description:Inhibition of Hepatitis C virus NS5B RNA-dependent RNA polymerase P495L mutantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepacivirus C)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50484980(CHEMBL2017861)
Affinity DataIC50:  4.84E+3nMAssay Description:Inhibition of Hepatitis C virus NS5B RNA-dependent RNA polymerase P495L mutantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepacivirus C)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50484979(CHEMBL2017860)
Affinity DataIC50:  5.10E+3nMAssay Description:Inhibition of Hepatitis C virus NS5B RNA-dependent RNA polymerase P495L mutantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepacivirus C)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50484978(CHEMBL2017857)
Affinity DataIC50:  5.85E+3nMAssay Description:Inhibition of Hepatitis C virus NS5B RNA-dependent RNA polymerase P495L mutantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50448498(BMS-791325 | Beclabuvir)
Affinity DataIC50: >4.00E+4nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50448498(BMS-791325 | Beclabuvir)
Affinity DataIC50: >4.00E+4nMAssay Description:Inhibition of CYP1A2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50448498(BMS-791325 | Beclabuvir)
Affinity DataIC50: >4.00E+4nMAssay Description:Inhibition of CYP2C19 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50448498(BMS-791325 | Beclabuvir)
Affinity DataIC50: >4.00E+4nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNuclear receptor subfamily 1 group I member 2(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50448499(CHEMBL3126841)
Affinity DataEC50: >5.00E+4nMAssay Description:Transactivation of human PXR expressed in human HepG2 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNuclear receptor subfamily 1 group I member 2(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50448500(CHEMBL3126840)
Affinity DataEC50:  3.00E+3nMAssay Description:Transactivation of human PXR expressed in human HepG2 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNuclear receptor subfamily 1 group I member 2(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50448501(CHEMBL3126839)
Affinity DataEC50:  1.00E+3nMAssay Description:Transactivation of human PXR expressed in human HepG2 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNuclear receptor subfamily 1 group I member 2(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50448502(CHEMBL3126838)
Affinity DataEC50: >5.00E+4nMAssay Description:Transactivation of human PXR expressed in human HepG2 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNuclear receptor subfamily 1 group I member 2(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50448503(CHEMBL3126837)
Affinity DataEC50:  9.00E+3nMAssay Description:Transactivation of human PXR expressed in human HepG2 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNuclear receptor subfamily 1 group I member 2(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50448495(CHEMBL3126836)
Affinity DataEC50:  2.00E+3nMAssay Description:Transactivation of human PXR expressed in human HepG2 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNuclear receptor subfamily 1 group I member 2(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50448496(CHEMBL3126835)
Affinity DataEC50: >5.00E+4nMAssay Description:Transactivation of human PXR expressed in human HepG2 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNuclear receptor subfamily 1 group I member 2(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50448497(CHEMBL3126834)
Affinity DataEC50: >5.00E+4nMAssay Description:Transactivation of human PXR expressed in human HepG2 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNuclear receptor subfamily 1 group I member 2(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50448504(CHEMBL3126658)
Affinity DataEC50: >5.00E+4nMAssay Description:Transactivation of human PXR expressed in human HepG2 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNuclear receptor subfamily 1 group I member 2(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50448494(CHEMBL3126657)
Affinity DataEC50: >5.00E+4nMAssay Description:Transactivation of human PXR expressed in human HepG2 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNuclear receptor subfamily 1 group I member 2(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50448505(CHEMBL3126656)
Affinity DataEC50: >5.00E+4nMAssay Description:Transactivation of human PXR expressed in human HepG2 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNuclear receptor subfamily 1 group I member 2(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50448506(CHEMBL3126655)
Affinity DataEC50: >5.00E+4nMAssay Description:Transactivation of human PXR expressed in human HepG2 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNuclear receptor subfamily 1 group I member 2(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50448507(CHEMBL3126861)
Affinity DataEC50: >5.00E+4nMAssay Description:Transactivation of human PXR expressed in human HepG2 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNuclear receptor subfamily 1 group I member 2(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50448508(CHEMBL3126860)
Affinity DataEC50: >5.00E+4nMAssay Description:Transactivation of human PXR expressed in human HepG2 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNuclear receptor subfamily 1 group I member 2(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50448509(CHEMBL3126859)
Affinity DataEC50: >5.00E+4nMAssay Description:Transactivation of human PXR expressed in human HepG2 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNuclear receptor subfamily 1 group I member 2(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50448510(CHEMBL3126858)
Affinity DataEC50: >5.00E+4nMAssay Description:Transactivation of human PXR expressed in human HepG2 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNuclear receptor subfamily 1 group I member 2(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50448511(CHEMBL3126857)
Affinity DataEC50: >5.00E+4nMAssay Description:Transactivation of human PXR expressed in human HepG2 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNuclear receptor subfamily 1 group I member 2(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50448512(CHEMBL3126856)
Affinity DataEC50: >5.00E+4nMAssay Description:Transactivation of human PXR expressed in human HepG2 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNuclear receptor subfamily 1 group I member 2(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50448513(CHEMBL3126855)
Affinity DataEC50: >5.00E+4nMAssay Description:Transactivation of human PXR expressed in human HepG2 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNuclear receptor subfamily 1 group I member 2(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50448514(CHEMBL3126854)
Affinity DataEC50: >3.00E+3nMAssay Description:Transactivation of human PXR expressed in human HepG2 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNuclear receptor subfamily 1 group I member 2(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50448515(CHEMBL3126853)
Affinity DataEC50: >5.00E+4nMAssay Description:Transactivation of human PXR expressed in human HepG2 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNuclear receptor subfamily 1 group I member 2(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50448516(CHEMBL3126852)
Affinity DataEC50: >5.00E+4nMAssay Description:Transactivation of human PXR expressed in human HepG2 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNuclear receptor subfamily 1 group I member 2(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50448517(CHEMBL3126851)
Affinity DataEC50:  600nMAssay Description:Transactivation of human PXR expressed in human HepG2 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNuclear receptor subfamily 1 group I member 2(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50448518(CHEMBL3126849)
Affinity DataEC50: >5.00E+4nMAssay Description:Transactivation of human PXR expressed in human HepG2 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50448495(CHEMBL3126836)
Affinity DataEC50:  7.00E+3nMAssay Description:Inhibition of CYP2C9 in human liver microsomes after 30 mins in presence of NADPHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50448496(CHEMBL3126835)
Affinity DataEC50: >4.00E+4nMAssay Description:Inhibition of CYP2C9 in human liver microsomes after 30 mins in presence of NADPHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNuclear receptor subfamily 1 group I member 2(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50448498(BMS-791325 | Beclabuvir)
Affinity DataEC50: >5.00E+4nMAssay Description:Transactivation of human PXR expressed in human HepG2 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50448497(CHEMBL3126834)
Affinity DataEC50: >4.00E+4nMAssay Description:Inhibition of CYP2C9 in human liver microsomes after 30 mins in presence of NADPHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50448494(CHEMBL3126657)
Affinity DataEC50: >4.00E+4nMAssay Description:Inhibition of CYP2C19 in human liver microsomes after 30 mins in presence of NADPHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50448497(CHEMBL3126834)
Affinity DataEC50: >4.00E+4nMAssay Description:Inhibition of CYP2C19 in human liver microsomes after 30 mins in presence of NADPHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50448496(CHEMBL3126835)
Affinity DataEC50: >4.00E+4nMAssay Description:Inhibition of CYP2C19 in human liver microsomes after 30 mins in presence of NADPHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50448495(CHEMBL3126836)
Affinity DataEC50:  3.10E+4nMAssay Description:Inhibition of CYP2C19 in human liver microsomes after 30 mins in presence of NADPHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50448494(CHEMBL3126657)
Affinity DataEC50: >4.00E+4nMAssay Description:Inhibition of CYP2D6 in human liver microsomes after 30 mins in presence of NADPHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50448497(CHEMBL3126834)
Affinity DataEC50: >4.00E+4nMAssay Description:Inhibition of CYP2D6 in human liver microsomes after 30 mins in presence of NADPHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50448496(CHEMBL3126835)
Affinity DataEC50: >4.00E+4nMAssay Description:Inhibition of CYP2D6 in human liver microsomes after 30 mins in presence of NADPHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50448495(CHEMBL3126836)
Affinity DataEC50: >4.00E+4nMAssay Description:Inhibition of CYP2D6 in human liver microsomes after 30 mins in presence of NADPHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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