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Found 68 with Last Name = 'hyjazie' and Initial = 'h'
TargetP2Y purinoceptor 14(Mus musculus)
Merck Frosst Center For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50343131(2-(2-cyanopyrimidin-5-yl)-N-(3-ethylphenyl)-4-o-to...)
Affinity DataIC50:  1nMAssay Description:Antagonist activity at mouse P2Y14 expressed in human HEK cells coexpressing Galphai5 assessed as inhibition of UDP-glucose stimulated calcium releas...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 14(Mus musculus)
Merck Frosst Center For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50343129(2-(4-cyanopyridin-3-yl)-N-(3-ethylphenyl)-4-o-toly...)
Affinity DataIC50:  3nMAssay Description:Antagonist activity at mouse P2Y14 expressed in human HEK cells coexpressing Galphai5 assessed as inhibition of UDP-glucose stimulated calcium releas...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 14(Mus musculus)
Merck Frosst Center For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50343886((R)-4-(4-(2,2,2-trifluoro-1-hydroxyethyl)phenyl)-7...)
Affinity DataIC50:  4nMAssay Description:Antagonist activity at mouse P2Y14 receptor expressed in HEK293 cells assessed as calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 14(Mus musculus)
Merck Frosst Center For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50343132(2-(3,5-dimethylisoxazol-4-yl)-N-(3-ethylphenyl)-4-...)
Affinity DataIC50:  4nMAssay Description:Antagonist activity at mouse P2Y14 expressed in human HEK cells coexpressing Galphai5 assessed as inhibition of UDP-glucose stimulated calcium releas...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 14(Mus musculus)
Merck Frosst Center For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50343888((R)-4-(4-(2,2-difluoro-1-hydroxyethyl)phenyl)-7-(4...)
Affinity DataIC50:  8nMAssay Description:Antagonist activity at mouse P2Y14 receptor expressed in HEK293 cells assessed as calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 14(Mus musculus)
Merck Frosst Center For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50343120(4-(2,6-dimethylphenyl)-N-(3-ethylphenyl)-2-(pyridi...)
Affinity DataIC50:  9nMAssay Description:Antagonist activity at mouse P2Y14 expressed in human HEK cells coexpressing Galphai5 assessed as inhibition of UDP-glucose stimulated calcium releas...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 14(Mus musculus)
Merck Frosst Center For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50343128(2-(benzo[d][1,3]dioxol-5-yl)-N-(3-ethylphenyl)-4-o...)
Affinity DataIC50:  10nMAssay Description:Antagonist activity at mouse P2Y14 expressed in human HEK cells coexpressing Galphai5 assessed as inhibition of UDP-glucose stimulated calcium releas...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 14(Mus musculus)
Merck Frosst Center For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50343130(CHEMBL1771458 | N-(3-ethylphenyl)-2-(pyrimidin-5-y...)
Affinity DataIC50:  12nMAssay Description:Antagonist activity at mouse P2Y14 expressed in human HEK cells coexpressing Galphai5 assessed as inhibition of UDP-glucose stimulated calcium releas...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 14(Mus musculus)
Merck Frosst Center For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50343127(CHEMBL1771455 | N-(3-ethylphenyl)-2-(quinolin-3-yl...)
Affinity DataIC50:  13nMAssay Description:Antagonist activity at mouse P2Y14 expressed in human HEK cells coexpressing Galphai5 assessed as inhibition of UDP-glucose stimulated calcium releas...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 14(Mus musculus)
Merck Frosst Center For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50343885(4-(4-(2,2,2-trifluoro-1-hydroxyethyl)phenyl)-7-(4-...)
Affinity DataIC50:  13nMAssay Description:Antagonist activity at mouse P2Y14 receptor expressed in HEK293 cells assessed as calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 14(Mus musculus)
Merck Frosst Center For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50343877(7-(4-fluoro-2,6-dimethylbenzyloxy)-4-(thiophen-3-y...)
Affinity DataIC50:  14nMAssay Description:Antagonist activity at mouse P2Y14 receptor expressed in HEK293 cells assessed as calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 14(Mus musculus)
Merck Frosst Center For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50343094(2-(4-cyanophenyl)-N-(3-ethylphenyl)-4-o-tolyl-7,8-...)
Affinity DataIC50:  16nMAssay Description:Antagonist activity at mouse P2Y14 expressed in human HEK cells coexpressing Galphai5 assessed as inhibition of UDP-glucose stimulated calcium releas...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 14(Mus musculus)
Merck Frosst Center For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50343884(4-(4-(methylsulfonyl)phenyl)-7-(4-(trifluoromethyl...)
Affinity DataIC50:  20nMAssay Description:Antagonist activity at mouse P2Y14 receptor expressed in HEK293 cells assessed as calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 14(Mus musculus)
Merck Frosst Center For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50343095(CHEMBL1771452 | N-(3-ethylphenyl)-2-(4-fluoropheny...)
Affinity DataIC50:  25nMAssay Description:Antagonist activity at mouse P2Y14 expressed in human HEK cells coexpressing Galphai5 assessed as inhibition of UDP-glucose stimulated calcium releas...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 14(Mus musculus)
Merck Frosst Center For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50343876(7-(2,6-dimethylbenzyloxy)-4-(thiophen-3-yl)-2-naph...)
Affinity DataIC50:  26nMAssay Description:Antagonist activity at mouse P2Y14 receptor expressed in HEK293 cells assessed as calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 14(Mus musculus)
Merck Frosst Center For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50343109(CHEMBL1771244 | N-(3-(1-fluoroethyl)phenyl)-2-(pyr...)
Affinity DataIC50:  29nMAssay Description:Antagonist activity at mouse P2Y14 expressed in human HEK cells coexpressing Galphai5 assessed as inhibition of UDP-glucose stimulated calcium releas...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 14(Mus musculus)
Merck Frosst Center For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50343125(CHEMBL1771453 | N-(3-ethylphenyl)-2-(3-fluoropheny...)
Affinity DataIC50:  30nMAssay Description:Antagonist activity at mouse P2Y14 expressed in human HEK cells coexpressing Galphai5 assessed as inhibition of UDP-glucose stimulated calcium releas...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 14(Mus musculus)
Merck Frosst Center For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50343121(4-(2-chloro-6-methylphenyl)-N-(3-ethylphenyl)-2-(p...)
Affinity DataIC50:  50nMAssay Description:Antagonist activity at mouse P2Y14 expressed in human HEK cells coexpressing Galphai5 assessed as inhibition of UDP-glucose stimulated calcium releas...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 14(Mus musculus)
Merck Frosst Center For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50343887((S)-4-(4-(2,2,2-trifluoro-1-hydroxyethyl)phenyl)-7...)
Affinity DataIC50:  51nMAssay Description:Antagonist activity at mouse P2Y14 receptor expressed in HEK293 cells assessed as calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 14(Mus musculus)
Merck Frosst Center For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50343122(4-(2,6-dichlorophenyl)-N-(3-ethylphenyl)-2-(pyridi...)
Affinity DataIC50:  51nMAssay Description:Antagonist activity at mouse P2Y14 expressed in human HEK cells coexpressing Galphai5 assessed as inhibition of UDP-glucose stimulated calcium releas...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 14(Mus musculus)
Merck Frosst Center For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50343878(4-(thiophen-3-yl)-7-(4-(trifluoromethoxy)phenyl)-2...)
Affinity DataIC50:  54nMAssay Description:Antagonist activity at mouse P2Y14 receptor expressed in HEK293 cells assessed as calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 14(Mus musculus)
Merck Frosst Center For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50343090(CHEMBL1771446 | N-(3-ethylphenyl)-4-o-tolyl-2-p-to...)
Affinity DataIC50:  62nMAssay Description:Antagonist activity at mouse P2Y14 expressed in human HEK cells coexpressing Galphai5 assessed as inhibition of UDP-glucose stimulated calcium releas...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 14(Mus musculus)
Merck Frosst Center For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50343103(CHEMBL1771238 | N-(3-ethylphenyl)-2-(pyridin-3-yl)...)
Affinity DataIC50:  81nMAssay Description:Antagonist activity at mouse P2Y14 expressed in human HEK cells coexpressing Galphai5 assessed as inhibition of UDP-glucose stimulated calcium releas...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 14(Mus musculus)
Merck Frosst Center For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50343089(CHEMBL1771445 | N-(3-ethylphenyl)-2-phenyl-4-o-tol...)
Affinity DataIC50:  87nMAssay Description:Antagonist activity at mouse P2Y14 expressed in human HEK cells coexpressing Galphai5 assessed as inhibition of UDP-glucose stimulated calcium releas...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 14(Mus musculus)
Merck Frosst Center For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50343875(4-(benzyloxy)-7-(2,6-dimethylbenzyloxy)-2-naphthoi...)
Affinity DataIC50:  110nMAssay Description:Antagonist activity at mouse P2Y14 receptor expressed in HEK293 cells assessed as calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 14(Mus musculus)
Merck Frosst Center For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50343872(7-(2,6-dimethylbenzyloxy)-4-phenyl-2-naphthoic aci...)
Affinity DataIC50:  110nMAssay Description:Antagonist activity at mouse P2Y14 receptor expressed in HEK293 cells assessed as calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 14(Mus musculus)
Merck Frosst Center For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50343093(2-(3-cyanophenyl)-N-(3-ethylphenyl)-4-o-tolyl-7,8-...)
Affinity DataIC50:  140nMAssay Description:Antagonist activity at mouse P2Y14 expressed in human HEK cells coexpressing Galphai5 assessed as inhibition of UDP-glucose stimulated calcium releas...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 14(Mus musculus)
Merck Frosst Center For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50343104(CHEMBL1771239 | N-(3-propylphenyl)-2-(pyridin-3-yl...)
Affinity DataIC50:  150nMAssay Description:Antagonist activity at mouse P2Y14 expressed in human HEK cells coexpressing Galphai5 assessed as inhibition of UDP-glucose stimulated calcium releas...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 14(Mus musculus)
Merck Frosst Center For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50343111(CHEMBL1771246 | N-(3-chloro-5-ethylphenyl)-2-(pyri...)
Affinity DataIC50:  160nMAssay Description:Antagonist activity at mouse P2Y14 expressed in human HEK cells coexpressing Galphai5 assessed as inhibition of UDP-glucose stimulated calcium releas...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 14(Mus musculus)
Merck Frosst Center For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50343871(7-(2,6-dichlorobenzyloxy)-4-phenyl-2-naphthoic aci...)
Affinity DataIC50:  190nMAssay Description:Antagonist activity at mouse P2Y14 receptor expressed in HEK293 cells assessed as calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 14(Mus musculus)
Merck Frosst Center For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50343883(4-(4-(methylsulfonyl)thiophen-3-yl)-7-(4-(trifluor...)
Affinity DataIC50:  190nMAssay Description:Antagonist activity at mouse P2Y14 receptor expressed in HEK293 cells assessed as calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 14(Mus musculus)
Merck Frosst Center For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50343882(4-(4-(methylsulfonyl)thiophen-3-yl)-7-(4-(trifluor...)
Affinity DataIC50:  330nMAssay Description:Antagonist activity at mouse P2Y14 receptor expressed in HEK293 cells assessed as calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 14(Mus musculus)
Merck Frosst Center For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50343881(4-(4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)...)
Affinity DataIC50:  350nMAssay Description:Antagonist activity at mouse P2Y14 receptor expressed in HEK293 cells assessed as calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 14(Mus musculus)
Merck Frosst Center For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50343879(3-fluoro-4-(thiophen-3-yl)-7-(4-(trifluoromethoxy)...)
Affinity DataIC50:  380nMAssay Description:Antagonist activity at mouse P2Y14 receptor expressed in HEK293 cells assessed as calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 14(Mus musculus)
Merck Frosst Center For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50343116(4-(2-ethylphenyl)-N-(3-ethylphenyl)-2-(pyridin-3-y...)
Affinity DataIC50:  390nMAssay Description:Antagonist activity at mouse P2Y14 expressed in human HEK cells coexpressing Galphai5 assessed as inhibition of UDP-glucose stimulated calcium releas...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 14(Mus musculus)
Merck Frosst Center For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50343100(CHEMBL1771235 | N-(3-ethoxyphenyl)-2-(pyridin-3-yl...)
Affinity DataIC50:  420nMAssay Description:Antagonist activity at mouse P2Y14 expressed in human HEK cells coexpressing Galphai5 assessed as inhibition of UDP-glucose stimulated calcium releas...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 14(Mus musculus)
Merck Frosst Center For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50343112(4-(2-chlorophenyl)-N-(3-ethylphenyl)-2-(pyridin-3-...)
Affinity DataIC50:  440nMAssay Description:Antagonist activity at mouse P2Y14 expressed in human HEK cells coexpressing Galphai5 assessed as inhibition of UDP-glucose stimulated calcium releas...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 14(Mus musculus)
Merck Frosst Center For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50343097(CHEMBL1771232 | N-(3-chlorophenyl)-2-(pyridin-3-yl...)
Affinity DataIC50:  580nMAssay Description:Antagonist activity at mouse P2Y14 expressed in human HEK cells coexpressing Galphai5 assessed as inhibition of UDP-glucose stimulated calcium releas...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 14(Mus musculus)
Merck Frosst Center For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50343110(CHEMBL1771245 | N-(3-(1,1-difluoroethyl)phenyl)-2-...)
Affinity DataIC50:  620nMAssay Description:Antagonist activity at mouse P2Y14 expressed in human HEK cells coexpressing Galphai5 assessed as inhibition of UDP-glucose stimulated calcium releas...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 14(Mus musculus)
Merck Frosst Center For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50343101(CHEMBL1771236 | N-(3-(methylthio)phenyl)-2-(pyridi...)
Affinity DataIC50:  630nMAssay Description:Antagonist activity at mouse P2Y14 expressed in human HEK cells coexpressing Galphai5 assessed as inhibition of UDP-glucose stimulated calcium releas...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 14(Mus musculus)
Merck Frosst Center For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50343126(CHEMBL1771454 | N-(3-ethylphenyl)-2-(naphthalen-2-...)
Affinity DataIC50:  880nMAssay Description:Antagonist activity at mouse P2Y14 expressed in human HEK cells coexpressing Galphai5 assessed as inhibition of UDP-glucose stimulated calcium releas...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 14(Mus musculus)
Merck Frosst Center For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50343119(CHEMBL1771438 | N-(3-ethylphenyl)-4-(2-(hydroxymet...)
Affinity DataIC50:  1.10E+3nMAssay Description:Antagonist activity at mouse P2Y14 expressed in human HEK cells coexpressing Galphai5 assessed as inhibition of UDP-glucose stimulated calcium releas...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 14(Mus musculus)
Merck Frosst Center For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50343106(CHEMBL1771241 | N-(3-cyclopropylphenyl)-2-(pyridin...)
Affinity DataIC50:  1.20E+3nMAssay Description:Antagonist activity at mouse P2Y14 expressed in human HEK cells coexpressing Galphai5 assessed as inhibition of UDP-glucose stimulated calcium releas...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 14(Mus musculus)
Merck Frosst Center For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50343105(2-(pyridin-3-yl)-4-o-tolyl-N-(3-vinylphenyl)-7,8-d...)
Affinity DataIC50:  1.20E+3nMAssay Description:Antagonist activity at mouse P2Y14 expressed in human HEK cells coexpressing Galphai5 assessed as inhibition of UDP-glucose stimulated calcium releas...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 14(Mus musculus)
Merck Frosst Center For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50343880(3-hydroxy-4-(thiophen-3-yl)-7-(4-(trifluoromethoxy...)
Affinity DataIC50:  1.30E+3nMAssay Description:Antagonist activity at mouse P2Y14 receptor expressed in HEK293 cells assessed as calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 14(Mus musculus)
Merck Frosst Center For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50343091(CHEMBL1771447 | N-(3-ethylphenyl)-2-m-tolyl-4-o-to...)
Affinity DataIC50:  1.30E+3nMAssay Description:Antagonist activity at mouse P2Y14 expressed in human HEK cells coexpressing Galphai5 assessed as inhibition of UDP-glucose stimulated calcium releas...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 14(Mus musculus)
Merck Frosst Center For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50343124(CHEMBL1771444 | N-(3-ethylphenyl)-2-(pyridin-4-yl)...)
Affinity DataIC50:  1.40E+3nMAssay Description:Antagonist activity at mouse P2Y14 expressed in human HEK cells coexpressing Galphai5 assessed as inhibition of UDP-glucose stimulated calcium releas...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 14(Mus musculus)
Merck Frosst Center For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50343102(2-(pyridin-3-yl)-N-m-tolyl-4-o-tolyl-7,8-dihydropy...)
Affinity DataIC50:  1.90E+3nMAssay Description:Antagonist activity at mouse P2Y14 expressed in human HEK cells coexpressing Galphai5 assessed as inhibition of UDP-glucose stimulated calcium releas...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 14(Mus musculus)
Merck Frosst Center For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50343873(7-((2,6-dimethylphenoxy)methyl)-4-phenyl-2-naphtho...)
Affinity DataIC50:  2.10E+3nMAssay Description:Antagonist activity at mouse P2Y14 receptor expressed in HEK293 cells assessed as calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 14(Mus musculus)
Merck Frosst Center For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50343123(3-(6-(3-ethylphenylcarbamoyl)-4-o-tolyl-5,6,7,8-te...)
Affinity DataIC50:  2.80E+3nMAssay Description:Antagonist activity at mouse P2Y14 expressed in human HEK cells coexpressing Galphai5 assessed as inhibition of UDP-glucose stimulated calcium releas...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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