Compile Data Set for Download or QSAR
maximum 50k data
Found 948 with Last Name = 'ihnat' and Initial = 'm'
TargetAminopeptidase N(Homo sapiens (Human))
The University Of Oklahoma Health Sciences Center

Curated by ChEMBL
LigandPNGBDBM50435737(PROBESTIN)
Affinity DataKi:  19nMAssay Description:Inhibition of aminopeptidase N (unknown origin) using L-leucine-beta-naphthylamide as substrate after 15 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50232828(CHEMBL4099329)
Affinity DataIC50:  1.10nMAssay Description:Inhibition of EGFR in human A431 cells assessed as reduction in EGF induced phosphorylation preincubated for 60 mins followed by EGF addition measure...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM5446(CHEMBL553 | ERLOTINIB HYDROCHLORIDE | Erlotinib | ...)
Affinity DataIC50:  1.20nMAssay Description:Inhibition of EGFR in human A431 cells by phosphotyrosine ELISA assayMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM5446(CHEMBL553 | ERLOTINIB HYDROCHLORIDE | Erlotinib | ...)
Affinity DataIC50:  1.20nMAssay Description:Inhibition of EGFR in human A431 cells assessed as reduction in EGF induced phosphorylation preincubated for 60 mins followed by EGF addition measure...More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM5446(CHEMBL553 | ERLOTINIB HYDROCHLORIDE | Erlotinib | ...)
Affinity DataIC50:  1.20nMAssay Description:Inhibition of EGF-induced EGFR activation in human A431 cells pretreated for 60 mins followed by EGF addition and measured after 10 mins by ELISAMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM5446(CHEMBL553 | ERLOTINIB HYDROCHLORIDE | Erlotinib | ...)
Affinity DataIC50:  1.20nMAssay Description:Inhibition of EGFR in human A431 cells preincubated for 60 mins followed by EGF stimulation and measured after 10 mins by ELISAMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM5446(CHEMBL553 | ERLOTINIB HYDROCHLORIDE | Erlotinib | ...)
Affinity DataIC50:  1.20nMAssay Description:Inhibition of EGFR in human A431 cells compound pretreated for 60 min before EGF stimulation for 10 mins by phosphotyrosine ELISA cytoblot methodMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50232824(CHEMBL4060996)
Affinity DataIC50:  2.30nMAssay Description:Inhibition of EGFR in human A431 cells assessed as reduction in EGF induced phosphorylation preincubated for 60 mins followed by EGF addition measure...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50232823(CHEMBL4099682)
Affinity DataIC50:  2.60nMAssay Description:Inhibition of EGFR in human A431 cells assessed as reduction in EGF induced phosphorylation preincubated for 60 mins followed by EGF addition measure...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTubulin beta-3 chain(Homo sapiens)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50552403(CHEMBL4800264)
Affinity DataIC50:  2.60nMAssay Description:Inhibition of beta3 Tubulin (unknown origin) expressed in human HeLa cell line assessed as inhibition of cell proliferation measured after 48 hrs by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50557539(Azixa | MPC-6827 | MX-128495 | Verubulin)
Affinity DataIC50:  2.80nMAssay Description:Inhibition of EGFR in human A431 cells preincubated for 60 mins followed by EGF stimulation and measured after 10 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50463626(CHEMBL4245415)
Affinity DataIC50:  3.10nMAssay Description:Inhibition of EGF-induced EGFR activation in human A431 cells pretreated for 60 mins followed by EGF addition and measured after 10 mins by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50069096(CHEMBL3403517 | US10189853, Compound 10)
Affinity DataIC50:  3.40nMAssay Description:Inhibition of EGFR in human A431 cells compound pretreated for 60 min before EGF stimulation for 10 mins by phosphotyrosine ELISA cytoblot methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50557544(CHEMBL444724)
Affinity DataIC50:  3.60nMAssay Description:Inhibition of EGFR in human A431 cells preincubated for 60 mins followed by EGF stimulation and measured after 10 mins by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50463635(CHEMBL4242522)
Affinity DataIC50:  4nMAssay Description:Inhibition of EGF-induced EGFR activation in human A431 cells pretreated for 60 mins followed by EGF addition and measured after 10 mins by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50232827(CHEMBL4104515)
Affinity DataIC50:  4.90nMAssay Description:Inhibition of EGFR in human A431 cells assessed as reduction in EGF induced phosphorylation preincubated for 60 mins followed by EGF addition measure...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50557540(CHEMBL2420866)
Affinity DataIC50:  5nMAssay Description:Inhibition of EGFR in human A431 cells preincubated for 60 mins followed by EGF stimulation and measured after 10 mins by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50557545(CHEMBL2420867)
Affinity DataIC50:  5.40nMAssay Description:Inhibition of EGFR in human A431 cells preincubated for 60 mins followed by EGF stimulation and measured after 10 mins by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50557539(Azixa | MPC-6827 | MX-128495 | Verubulin)
Affinity DataIC50:  5.60nMAssay Description:Inhibition of PDGFRbeta in human SH-SY5Y cells preincubated for 60 mins followed by PDGF stimulation and measured after 10 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTubulin beta-3 chain(Homo sapiens)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50005480((-)-combretastatin | (Z)-3'-hydroxy-3,4,4',5-tetra...)
Affinity DataIC50:  5.70nMAssay Description:Inhibition of beta3 Tubulin (unknown origin) expressed in human HeLa cell line assessed as inhibition of cell proliferation measured after 48 hrs by ...More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50069093(CHEMBL3403514)
Affinity DataIC50:  5.80nMAssay Description:Inhibition of VEGFR2 in human U251 cells compound pretreated for 60 min before VEGF stimulation for 10 mins by phosphotyrosine ELISA cytoblot methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50051308((3-Chloro-phenyl)-(9H-pyrimido[4,5-b]indol-4-yl)-a...)
Affinity DataIC50:  6nMAssay Description:Inhibition of EGFR in human A431 cells assessed as inhibition of EGF-induced tyrosine phosphorylation incubated for 60 mins prior to EGF-activation m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50463628(CHEMBL4250210)
Affinity DataIC50:  6.40nMAssay Description:Inhibition of EGF-induced EGFR activation in human A431 cells pretreated for 60 mins followed by EGF addition and measured after 10 mins by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50069099(CHEMBL3403513)
Affinity DataIC50:  6.70nMAssay Description:Inhibition of VEGFR2 in human U251 cells compound pretreated for 60 min before VEGF stimulation for 10 mins by phosphotyrosine ELISA cytoblot methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50463629(CHEMBL4237916)
Affinity DataIC50:  7.10nMAssay Description:Inhibition of EGF-induced EGFR activation in human A431 cells pretreated for 60 mins followed by EGF addition and measured after 10 mins by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50232823(CHEMBL4099682)
Affinity DataIC50:  7.20nMAssay Description:Inhibition of PDGFR-beta in human SF539 cells assessed as reduction in PDGF-BB induced phosphorylation preincubated for 60 mins followed by PDGF-BB a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50463623(CHEMBL4239716)
Affinity DataIC50:  7.20nMAssay Description:Inhibition of EGF-induced EGFR activation in human A431 cells pretreated for 60 mins followed by EGF addition and measured after 10 mins by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTubulin beta-3 chain(Homo sapiens)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50001839(CHEMBL428647 | PACLITAXEL | taxol)
Affinity DataIC50:  7.70nMAssay Description:Inhibition of beta3 Tubulin (unknown origin) expressed in human HeLa cell line assessed as inhibition of cell proliferation measured after 48 hrs by ...More data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50557540(CHEMBL2420866)
Affinity DataIC50:  7.80nMAssay Description:Inhibition of PDGFRbeta in human SH-SY5Y cells preincubated for 60 mins followed by PDGF stimulation and measured after 10 mins by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50463635(CHEMBL4242522)
Affinity DataIC50:  7.80nMAssay Description:Inhibition of VEGF-induced VEGFR2 activation in human U251 cells pretreated for 60 mins followed by VEGF addition and measured after 10 mins by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50232828(CHEMBL4099329)
Affinity DataIC50:  8.10nMAssay Description:Inhibition of PDGFR-beta in human SF539 cells assessed as reduction in PDGF-BB induced phosphorylation preincubated for 60 mins followed by PDGF-BB a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50557539(Azixa | MPC-6827 | MX-128495 | Verubulin)
Affinity DataIC50:  8.40nMAssay Description:Inhibition of VEGFR2 in human U251 cells preincubated for 60 mins followed by VEGF stimulation and measured after 10 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50022503(CHEMBL3297900)
Affinity DataIC50:  8.5nMAssay Description:Inhibition of VEGFR2 in human U251 cells by phosphotyrosine ELISA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50557541(CHEMBL516047)
Affinity DataIC50:  8.70nMAssay Description:Inhibition of EGFR in human A431 cells preincubated for 60 mins followed by EGF stimulation and measured after 10 mins by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50557540(CHEMBL2420866)
Affinity DataIC50:  9.30nMAssay Description:Inhibition of VEGFR2 in human U251 cells preincubated for 60 mins followed by VEGF stimulation and measured after 10 mins by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50463632(CHEMBL4250191)
Affinity DataIC50:  9.30nMAssay Description:Inhibition of VEGF-induced VEGFR2 activation in human U251 cells pretreated for 60 mins followed by VEGF addition and measured after 10 mins by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTubulin beta-3 chain(Homo sapiens)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50552407(CHEMBL4758455)
Affinity DataIC50:  9.60nMAssay Description:Inhibition of beta3 Tubulin (unknown origin) expressed in human HeLa cell line assessed as inhibition of cell proliferation measured after 48 hrs by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTubulin beta-3 chain(Homo sapiens)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50552402(CHEMBL3040513)
Affinity DataIC50:  9.60nMAssay Description:Inhibition of beta3 Tubulin (unknown origin) expressed in human HeLa cell line assessed as inhibition of cell proliferation measured after 48 hrs by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50463630(CHEMBL4250273)
Affinity DataIC50:  10nMAssay Description:Inhibition of EGF-induced EGFR activation in human A431 cells pretreated for 60 mins followed by EGF addition and measured after 10 mins by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50232824(CHEMBL4060996)
Affinity DataIC50:  10nMAssay Description:Inhibition of PDGFR-beta in human SF539 cells assessed as reduction in PDGF-BB induced phosphorylation preincubated for 60 mins followed by PDGF-BB a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50557542(CHEMBL4746488)
Affinity DataIC50:  11nMAssay Description:Inhibition of EGFR in human A431 cells preincubated for 60 mins followed by EGF stimulation and measured after 10 mins by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50022522(CHEMBL3297899)
Affinity DataIC50:  11nMAssay Description:Inhibition of VEGFR2 in human U251 cells by phosphotyrosine ELISA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM5446(CHEMBL553 | ERLOTINIB HYDROCHLORIDE | Erlotinib | ...)
Affinity DataIC50:  12nMAssay Description:Inhibition of PDGFRbeta in human SH-SY5Y cells preincubated for 60 mins followed by PDGF stimulation and measured after 10 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50463629(CHEMBL4237916)
Affinity DataIC50:  12nMAssay Description:Inhibition of VEGF-induced VEGFR2 activation in human U251 cells pretreated for 60 mins followed by VEGF addition and measured after 10 mins by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50463632(CHEMBL4250191)
Affinity DataIC50:  12nMAssay Description:Inhibition of PDGF-BB-induced PDGFRbeta activation in human SH-SY5Y cells pretreated for 60 mins followed by PDGF-BB addition and measured after 10 m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM4810((3Z)-3-[(3,5-dimethyl-1H-pyrrol-2-yl)methylidene]-...)
Affinity DataIC50:  13nMAssay Description:Inhibition of VEGFR2 in human U251 cells by phosphotyrosine ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM4810((3Z)-3-[(3,5-dimethyl-1H-pyrrol-2-yl)methylidene]-...)
Affinity DataIC50:  13nMAssay Description:Inhibition of VEGFR-2 in human U251 cells assessed as reduction in VEGF induced phosphorylation preincubated for 60 mins followed by VEGF addition me...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50463628(CHEMBL4250210)
Affinity DataIC50:  13nMAssay Description:Inhibition of VEGF-induced VEGFR2 activation in human U251 cells pretreated for 60 mins followed by VEGF addition and measured after 10 mins by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM4810((3Z)-3-[(3,5-dimethyl-1H-pyrrol-2-yl)methylidene]-...)
Affinity DataIC50:  13nMAssay Description:Inhibition of VEGFR2 in human U251 cells by phosphotyrosine ELISA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM4810((3Z)-3-[(3,5-dimethyl-1H-pyrrol-2-yl)methylidene]-...)
Affinity DataIC50:  13nMAssay Description:Inhibition of VEGF-induced VEGFR2 activation in human U251 cells pretreated for 60 mins followed by VEGF addition and measured after 10 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Displayed 1 to 50 (of 948 total ) | Next | Last >>
Jump to: