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Found 598 with Last Name = 'ismail' and Initial = 'nh'
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
University Of Malaya

Curated by ChEMBL
LigandPNGBDBM8961(1,2,3,4-tetrahydro-9-acridinamine | 1,2,3,4-tetrah...)
Affinity DataIC50:  74nMAssay Description:Inhibition of Electrophorus electricus AChE after 120 secs by Ellman spectroscopic methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-glucuronidase(Homo sapiens (Human))
Universiti Teknologi Mara

LigandPNGBDBM193719(2-(4-(Di(1H-indol-3-yl)methyl)benzoyl)-N-(2-fluoro...)
Affinity DataIC50:  100nMAssay Description:β-Glucuronidase activity was determined by measuring the absorbance at 405 nm of p-nitrophenol formed from the substrate by the spectrophotometr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-glucuronidase(Homo sapiens (Human))
Universiti Teknologi Mara

LigandPNGBDBM193733(2-(4-(Di(1H-indol-3-yl)methyl)benzoyl)-N-(3,4-dich...)
Affinity DataIC50:  120nMAssay Description:β-Glucuronidase activity was determined by measuring the absorbance at 405 nm of p-nitrophenol formed from the substrate by the spectrophotometr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOligo-1,6-glucosidase IMA1(Saccharomyces cerevisiae S288c (Baker's yeast))
Universiti Teknologi Mara (Uitm), Puncak Alam Campus

LigandPNGBDBM60585(2-(3'-Fluorophenyl)-7-methyl-1H-benzo[d]imidazole ...)
Affinity DataIC50:  165nMAssay Description:The 135 無 of 50 mM phosphate saline buffer pH (6.8), solution of enzyme (20 無), and 20 無 of test sample with 70% DMSO was added to 96-well plate. ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Bos taurus)
Universiti Teknologi Mara (Uitm)

LigandPNGBDBM10880(AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...)
Affinity DataIC50:  180nMpH: 7.2Assay Description:This was assay performed using buffer containing Tris and HEPES at the pH of 7.2-7.9 and a total concentration of 20 mM. 96-well plates were filled w...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-glucuronidase(Homo sapiens (Human))
Universiti Teknologi Mara

LigandPNGBDBM193734(2-(4-(di(1H-indol-3-yl)methyl)benzoyl)-N-(4(triflu...)
Affinity DataIC50:  200nMAssay Description:β-Glucuronidase activity was determined by measuring the absorbance at 405 nm of p-nitrophenol formed from the substrate by the spectrophotometr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrease(Canavalia ensiformis (Jack bean) (Horse bean))
Universiti Teknologi Mara (Uitm)

Curated by ChEMBL
LigandPNGBDBM50129797(CHEMBL3629072)
Affinity DataIC50:  400nMAssay Description:Inhibition of jack bean urease using urea as substrate assessed as ammonia production incubated for 15 mins by indophenol methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-glucuronidase(Homo sapiens (Human))
Universiti Teknologi Mara

LigandPNGBDBM227609((E)-5-chloro-N'-(2,4,5-trihydroxybenzylidene)-...)
Affinity DataIC50:  500nMAssay Description:β-glucuronidase activity was determined in accordance to method used by Taha et al. [Taha et al., Bioorg. Med. Chem., 23:7394-7404] by measuring...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetBeta-glucuronidase(Homo sapiens (Human))
Universiti Teknologi Mara

LigandPNGBDBM193720(N-(2-Chlorophenyl)-2-(4-(di(1H-indol-3-yl)methyl)b...)
Affinity DataIC50:  500nMAssay Description:β-Glucuronidase activity was determined by measuring the absorbance at 405 nm of p-nitrophenol formed from the substrate by the spectrophotometr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-glucuronidase(Bos taurus (Bovine))
University Of Karachi

Curated by ChEMBL
LigandPNGBDBM50019283(CHEMBL3289121)
Affinity DataIC50:  700nMAssay Description:Compound was tested for TXA2 receptor antagonism by measuring its ability to inhibit contraction of rat aorta induced by the stable TXA2 agonist U-46...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
University Of Malaya

Curated by ChEMBL
LigandPNGBDBM50330755(CHEMBL1277588 | Mesuagenin B)
Affinity DataIC50:  700nMAssay Description:Inhibition of Electrophorus electricus AChE after 120 secs by Ellman spectroscopic methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrease(Canavalia ensiformis (Jack bean) (Horse bean))
Universiti Teknologi Mara (Uitm)

Curated by ChEMBL
LigandPNGBDBM50129738(CHEMBL3629545)
Affinity DataIC50:  700nMAssay Description:Inhibition of jack bean urease using urea as substrate assessed as ammonia production incubated for 15 mins by indophenol methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
University Of Malaya

Curated by ChEMBL
LigandPNGBDBM50330754(CHEMBL1277495 | Mesuagenin A)
Affinity DataIC50:  1.06E+3nMAssay Description:Inhibition of Electrophorus electricus AChE after 120 secs by Ellman spectroscopic methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrease(Canavalia ensiformis (Jack bean) (Horse bean))
Universiti Teknologi Mara (Uitm)

Curated by ChEMBL
LigandPNGBDBM50129802(CHEMBL3629548)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of jack bean urease using urea as substrate assessed as ammonia production incubated for 15 mins by indophenol methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-glucuronidase(Bos taurus (Bovine))
University Of Karachi

Curated by ChEMBL
LigandPNGBDBM50019166(CHEMBL336718)
Affinity DataIC50:  1.10E+3nMAssay Description:Compound was tested for TXA2 receptor antagonism by measuring its ability to inhibit contraction of rat aorta induced by the stable TXA2 agonist U-46...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-glucuronidase(Bos taurus (Bovine))
University Of Karachi

Curated by ChEMBL
LigandPNGBDBM50233861(CHEMBL4084524)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of bovine liver beta glucuronidase using p-nitrophenyl-beta-D-glucuronide as substrate preincubated for 30 mins followed by substrate addi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOligo-1,6-glucosidase IMA1(Saccharomyces cerevisiae S288c (Baker's yeast))
Universiti Teknologi Mara (Uitm), Puncak Alam Campus

LigandPNGBDBM178004(2-(3-((3-(trifluoromethyl)benzyl)oxy)phenyl)-4H-ch...)
Affinity DataIC50:  1.26E+3nMpH: 6.8Assay Description:The α-glucosidase inhibition assay had been carried out using baker窺 yeast a-glucosidase (EC 3.2.1.20) and p-nitrophenyl-α-D-glucopyranosi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPancreatic alpha-amylase(Sus scrofa (Pig))
University Of Dammam

Curated by ChEMBL
LigandPNGBDBM23406((3R,4R,5S,6R)-5-{[(2R,3R,4R,5S,6R)-5-{[(2R,3R,4S,5...)
Affinity DataIC50:  1.35E+3nMAssay Description:Inhibition of porcine pancreatic alpha-amylase using starch as substrate preincubated for 10 mins followed by substrate addition measured after 10 mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrease(Canavalia ensiformis (Jack bean) (Horse bean))
Universiti Teknologi Mara (Uitm)

Curated by ChEMBL
LigandPNGBDBM181084(2-(4-(benzo[d]thiazol-2-yl)benzoyl)-N-(4-nitrophen...)
Affinity DataIC50:  1.40E+3nMpH: 6.8 T: 2°CAssay Description:To understand the binding modes of the compounds given in Table 1, all ligands were docked into the binding site of Urease enzyme. The top ranked con...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrease(Canavalia ensiformis (Jack bean) (Horse bean))
Universiti Teknologi Mara (Uitm)

Curated by ChEMBL
LigandPNGBDBM50129798(CHEMBL3629071)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of jack bean urease using urea as substrate assessed as ammonia production incubated for 15 mins by indophenol methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrease(Canavalia ensiformis (Jack bean) (Horse bean))
Universiti Teknologi Mara (Uitm)

Curated by ChEMBL
LigandPNGBDBM50129744(CHEMBL3629078)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of jack bean urease using urea as substrate assessed as ammonia production incubated for 15 mins by indophenol methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrease(Canavalia ensiformis (Jack bean) (Horse bean))
Universiti Teknologi Mara (Uitm)

Curated by ChEMBL
LigandPNGBDBM50129746(CHEMBL3629076)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of jack bean urease using urea as substrate assessed as ammonia production incubated for 15 mins by indophenol methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPancreatic alpha-amylase(Sus scrofa (Pig))
University Of Dammam

Curated by ChEMBL
LigandPNGBDBM50464435(CHEMBL4277658)
Affinity DataIC50:  1.57E+3nMAssay Description:Inhibition of porcine pancreatic alpha-amylase using starch as substrate preincubated for 10 mins followed by substrate addition measured after 10 mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrease(Canavalia ensiformis (Jack bean) (Horse bean))
Universiti Teknologi Mara (Uitm)

Curated by ChEMBL
LigandPNGBDBM50129801(CHEMBL3629549)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition of jack bean urease using urea as substrate assessed as ammonia production incubated for 15 mins by indophenol methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrease(Canavalia ensiformis (Jack bean) (Horse bean))
Universiti Teknologi Mara (Uitm)

Curated by ChEMBL
LigandPNGBDBM60592(2-(4-(benzo[d]thiazol-2-yl)benzoyl)-N-(4-(trifluor...)
Affinity DataIC50:  1.60E+3nMpH: 6.8 T: 2°CAssay Description:To understand the binding modes of the compounds given in Table 1, all ligands were docked into the binding site of Urease enzyme. The top ranked con...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-glucuronidase(Bos taurus (Bovine))
University Of Karachi

Curated by ChEMBL
LigandPNGBDBM50277802(CHEMBL4172107)
Affinity DataIC50:  1.60E+3nMAssay Description:Antagonistic activity for inhibition of histamine H2 receptor from anesthetized ratsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrease(Canavalia ensiformis (Jack bean) (Horse bean))
Universiti Teknologi Mara (Uitm)

Curated by ChEMBL
LigandPNGBDBM50129804(CHEMBL3629546)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition of jack bean urease using urea as substrate assessed as ammonia production incubated for 15 mins by indophenol methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-glucuronidase(Bos taurus (Bovine))
University Of Karachi

Curated by ChEMBL
LigandPNGBDBM50019285(CHEMBL3289122)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibition of bovine liver beta-glucuronidase using p-nitrophenyl-beta-D-glucuronide as substrate preincubated for 30 mins followed by substrate addi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1/2(Bos taurus)
Universiti Kebangsaan Malaysia

Curated by ChEMBL
LigandPNGBDBM50140172(CHEBI:3962 | CHEMBL140 | Curcumin | US9409845, Tab...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of bovine seminal vesicle COX uing [1-14C]PGH2 as substrate by TLC/liquid scintillation spectrometry methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPancreatic alpha-amylase(Sus scrofa (Pig))
University Of Dammam

Curated by ChEMBL
LigandPNGBDBM50464425(CHEMBL4284909)
Affinity DataIC50:  2.06E+3nMAssay Description:Inhibition of porcine pancreatic alpha-amylase using starch as substrate preincubated for 10 mins followed by substrate addition measured after 10 mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-glucuronidase(Bos taurus (Bovine))
University Of Karachi

Curated by ChEMBL
LigandPNGBDBM50277979(CHEMBL4167683)
Affinity DataIC50:  2.10E+3nMAssay Description:Inhibition of bovine liver beta-glucuronidase using p-nitrophenyl-beta-D-glucuronide as substrate preincubated for 30 mins followed by substrate addi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrease(Canavalia ensiformis (Jack bean) (Horse bean))
Universiti Teknologi Mara (Uitm)

Curated by ChEMBL
LigandPNGBDBM181090(2-(4-(benzo[d]thiazol-2-yl)benzoyl)-N-(3,4-dichlor...)
Affinity DataIC50:  2.10E+3nMpH: 6.8 T: 2°CAssay Description:To understand the binding modes of the compounds given in Table 1, all ligands were docked into the binding site of Urease enzyme. The top ranked con...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-glucuronidase(Bos taurus (Bovine))
University Of Karachi

Curated by ChEMBL
LigandPNGBDBM50233856(CHEMBL4092265)
Affinity DataIC50:  2.10E+3nMAssay Description:Inhibition of bovine liver beta glucuronidase using p-nitrophenyl-beta-D-glucuronide as substrate preincubated for 30 mins followed by substrate addi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-glucuronidase(Homo sapiens (Human))
Universiti Teknologi Mara

LigandPNGBDBM50180370(CHEMBL3813774)
Affinity DataIC50:  2.11E+3nMAssay Description:Inhibition of beta-glucuronidase (unknown origin) using p-nitrophenyl-beta-D-glucuronide as substrate assessed as formation of p-nitrophenol incubate...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPancreatic alpha-amylase(Sus scrofa (Pig))
University Of Dammam

Curated by ChEMBL
LigandPNGBDBM50464440(CHEMBL4294256)
Affinity DataIC50:  2.12E+3nMAssay Description:Inhibition of porcine pancreatic alpha-amylase using starch as substrate preincubated for 10 mins followed by substrate addition measured after 10 mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBeta-glucuronidase(Homo sapiens (Human))
Universiti Teknologi Mara

LigandPNGBDBM50092444(CHEMBL3586121)
Affinity DataIC50:  2.14E+3nMAssay Description:Inhibition of beta-D-glucuronidase (unknown origin) assessed as reduction in p-nitrophenol formation using p-nitrophenyl-beta-D-glucuronide substarte...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-glucuronidase(Bos taurus (Bovine))
University Of Karachi

Curated by ChEMBL
LigandPNGBDBM50092444(CHEMBL3586121)
Affinity DataIC50:  2.14E+3nMAssay Description:Inhibition of bovine beta-glucuronidase assessed as p-nitrophenol formation preincubated for 30 mins followed by addition of p-nitrophenyl-beta-D-glu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-glucuronidase(Bos taurus (Bovine))
University Of Karachi

Curated by ChEMBL
LigandPNGBDBM50160569(CHEMBL3785671)
Affinity DataIC50:  2.16E+3nMAssay Description:Inhibition of bovine beta-glucuronidase assessed as p-nitrophenol formation preincubated for 30 mins followed by addition of p-nitrophenyl-beta-D-glu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-glucuronidase(Bos taurus (Bovine))
University Of Karachi

Curated by ChEMBL
LigandPNGBDBM193670(N,N'-(disulfanediylbis(2,1-phenylene))bis(2,4,...)
Affinity DataIC50:  2.20E+3nMAssay Description:β-glucuronidase activity was determined by measuring absorbance at 405 nm of p-nitrophenol formed substrate by spectrophotometric method. 250 無...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOligo-1,6-glucosidase IMA1(Saccharomyces cerevisiae S288c (Baker's yeast))
Universiti Teknologi Mara (Uitm), Puncak Alam Campus

LigandPNGBDBM173530((E)-N'-(3,4,5-trihydroxybenzylidene)-1H-indole...)
Affinity DataIC50:  2.30E+3nMAssay Description:The 135 無 of 50 mM phosphate saline buffer pH (6.8) was added in the 96-well plate and 20 無 of test sample with 70% DMSO added into the wells. The ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-glucuronidase(Homo sapiens (Human))
Universiti Teknologi Mara

LigandPNGBDBM193729(2-(4-(Di(1H-indol-3-yl)methyl)benzoyl)-N-(3-fluoro...)
Affinity DataIC50:  2.30E+3nMAssay Description:β-Glucuronidase activity was determined by measuring the absorbance at 405 nm of p-nitrophenol formed from the substrate by the spectrophotometr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPancreatic alpha-amylase(Sus scrofa (Pig))
University Of Dammam

Curated by ChEMBL
LigandPNGBDBM50464427(CHEMBL4292777)
Affinity DataIC50:  2.35E+3nMAssay Description:Inhibition of porcine pancreatic alpha-amylase using starch as substrate preincubated for 10 mins followed by substrate addition measured after 10 mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-glucuronidase(Homo sapiens (Human))
Universiti Teknologi Mara

LigandPNGBDBM227608((E)-5-chloro-N'-(2,4,6-trihydroxybenzylidene)-...)
Affinity DataIC50:  2.40E+3nMAssay Description:β-glucuronidase activity was determined in accordance to method used by Taha et al. [Taha et al., Bioorg. Med. Chem., 23:7394-7404] by measuring...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetBeta-glucuronidase(Homo sapiens (Human))
Universiti Teknologi Mara

LigandPNGBDBM222210(2,4,5-Trichloro-N'-(4-(5-(2-methoxyphenyl)-1,3...)
Affinity DataIC50:  2.40E+3nMAssay Description:β-glucuronidase activity was determined by measuring absorbance at 405 nm of p-nitrophenol formed substrate by spectrophotometric method. 250 &#...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBeta-glucuronidase(Homo sapiens (Human))
Universiti Teknologi Mara

LigandPNGBDBM227625((E)-5-chloro-N'-(2-fluorobenzylidene)-1H-indol...)
Affinity DataIC50:  2.50E+3nMAssay Description:β-glucuronidase activity was determined in accordance to method used by Taha et al. [Taha et al., Bioorg. Med. Chem., 23:7394-7404] by measuring...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetUrease(Canavalia ensiformis (Jack bean) (Horse bean))
Universiti Teknologi Mara (Uitm)

Curated by ChEMBL
LigandPNGBDBM181080(2-(4-(benzo[d]thiazol-2-yl)benzoyl)-N-(4-fluorophe...)
Affinity DataIC50:  2.50E+3nMpH: 6.8 T: 2°CAssay Description:To understand the binding modes of the compounds given in Table 1, all ligands were docked into the binding site of Urease enzyme. The top ranked con...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-glucuronidase(Homo sapiens (Human))
Universiti Teknologi Mara

LigandPNGBDBM50180368(CHEMBL3814932)
Affinity DataIC50:  2.60E+3nMAssay Description:Inhibition of beta-glucuronidase (unknown origin) using p-nitrophenyl-beta-D-glucuronide as substrate assessed as formation of p-nitrophenol incubate...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPancreatic alpha-amylase(Sus scrofa (Pig))
University Of Dammam

Curated by ChEMBL
LigandPNGBDBM50464428(CHEMBL4290115)
Affinity DataIC50:  2.67E+3nMAssay Description:Inhibition of porcine pancreatic alpha-amylase using starch as substrate preincubated for 10 mins followed by substrate addition measured after 10 mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBeta-glucuronidase(Homo sapiens (Human))
Universiti Teknologi Mara

LigandPNGBDBM227613((E)-4-((2-(5-chloro-1H-indole-2-carbonyl)hydrazono...)
Affinity DataIC50:  2.70E+3nMAssay Description:β-glucuronidase activity was determined in accordance to method used by Taha et al. [Taha et al., Bioorg. Med. Chem., 23:7394-7404] by measuring...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetPancreatic alpha-amylase(Sus scrofa (Pig))
University Of Dammam

Curated by ChEMBL
LigandPNGBDBM50464433(CHEMBL4286367)
Affinity DataIC50:  2.75E+3nMAssay Description:Inhibition of porcine pancreatic alpha-amylase using starch as substrate preincubated for 10 mins followed by substrate addition measured after 10 mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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