Compile Data Set for Download or QSAR
maximum 50k data
Found 89 with Last Name = 'jaitak' and Initial = 'v'
TargetSteryl-sulfatase(Rattus norvegicus)TBA
LigandPNGBDBM50148911((3beta)-3-hydroxyurs-12-en-28-oic acid | 3beta-hyd...)
Affinity DataIC50:  0.0600nMAssay Description:Inhibition of estrone sulfatase in homogeneous rat mammary tumorsMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetSteryl-sulfatase(Homo sapiens (Human))TBA
LigandPNGBDBM50148911((3beta)-3-hydroxyurs-12-en-28-oic acid | 3beta-hyd...)
Affinity DataIC50:  0.120nMAssay Description:Inhibition of estrone sulfatase in human MCF7 cell microsomesMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Central University Of Punjab

Curated by ChEMBL
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)
Affinity DataIC50: <1nMAssay Description:Inhibition of SYK (unknown origin)More data for this Ligand-Target Pair
TargetTyrosine-protein kinase Lyn(Homo sapiens (Human))
Central University Of Punjab

Curated by ChEMBL
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)
Affinity DataIC50: <1nMAssay Description:Inhibition of Lyn (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetSteryl-sulfatase(Homo sapiens (Human))TBA
LigandPNGBDBM50188235(CHEMBL3827021)
Affinity DataIC50:  1nMAssay Description:Inhibition of placental sulphatase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Central University Of Punjab

Curated by ChEMBL
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)
Affinity DataIC50: <1nMAssay Description:Inhibition of FLT3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Central University Of Punjab

Curated by ChEMBL
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)
Affinity DataIC50: <1nMAssay Description:Inhibition of ALK (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAurora kinase A(Homo sapiens (Human))
Central University Of Punjab

Curated by ChEMBL
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)
Affinity DataIC50: <1nMAssay Description:Inhibition of Aurora A(unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Central University Of Punjab

Curated by ChEMBL
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)
Affinity DataIC50:  1.80nMAssay Description:Inhibition of FGFR2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAromatase(Homo sapiens (Human))
Central University Of Punjab

Curated by ChEMBL
LigandPNGBDBM50587898(CHEMBL5195433)
Affinity DataIC50:  2.30nMAssay Description:Inhibition of human recombinant aromatase expressed in baculovirus insect cell using 7-methoxy-trifluoromethyl coumarin (MFC) as substrate preincubat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAromatase(Homo sapiens (Human))
Central University Of Punjab

Curated by ChEMBL
LigandPNGBDBM13061(4,4 -(1H-1,2,4-triazol-1-ylmethanediyl)dibenzonitr...)
Affinity DataIC50:  2.80nMAssay Description:Inhibition of human recombinant aromatase expressed in baculovirus insect cell using 7-methoxy-trifluoromethyl coumarin (MFC) as substrate preincubat...More data for this Ligand-Target Pair
In DepthDetails PubMedDrugBank

TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Central University Of Punjab

Curated by ChEMBL
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)
Affinity DataIC50:  4.5nMAssay Description:Inhibition of BRAF V599E mutant(unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Central University Of Punjab

Curated by ChEMBL
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)
Affinity DataIC50:  4.60nMAssay Description:Inhibition of AKT1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Central University Of Punjab

Curated by ChEMBL
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)
Affinity DataIC50:  14nMAssay Description:Inhibition of BRAF (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetEstrogen receptor(Homo sapiens (Human))
Central University Of Punjab

Curated by ChEMBL
LigandPNGBDBM50294178(CHEMBL4160682)
Affinity DataIC50:  33nMAssay Description:Displacement of fluoromone TM from recombinant human ERalpha after 2 hrs by fluorescence polarization analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Central University Of Punjab

Curated by ChEMBL
LigandPNGBDBM50294174(CHEMBL4170939)
Affinity DataIC50:  47nMAssay Description:Displacement of fluoromone TM from recombinant human ERalpha after 2 hrs by fluorescence polarization analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Central University Of Punjab

Curated by ChEMBL
LigandPNGBDBM9475(4-(1H-Imidazol-1-ylmethyl)-7-phenoxy-2H-chromen-2-...)
Affinity DataIC50:  51nMAssay Description:Inhibition of human placental microsomal aromatase using testosterone as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor alpha(Bos taurus)TBA
LigandPNGBDBM50610464(CHEMBL5284918)
Affinity DataIC50:  60nMAssay Description:Displacement of [3H]-17beta-estradiol from bovine uterine estrogen receptor by competitive binding assayMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetEstrogen receptor(Homo sapiens (Human))
Central University Of Punjab

Curated by ChEMBL
LigandPNGBDBM50294181(CHEMBL4169456)
Affinity DataIC50:  74nMAssay Description:Displacement of fluoromone TM from recombinant human ERalpha after 2 hrs by fluorescence polarization analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Central University Of Punjab

Curated by ChEMBL
LigandPNGBDBM50294182(CHEMBL4161120)
Affinity DataIC50:  77nMAssay Description:Displacement of fluoromone TM from recombinant human ERalpha after 2 hrs by fluorescence polarization analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Central University Of Punjab

Curated by ChEMBL
LigandPNGBDBM50294175(CHEMBL4167567)
Affinity DataIC50:  80nMAssay Description:Displacement of fluoromone TM from recombinant human ERalpha after 2 hrs by fluorescence polarization analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Central University Of Punjab

Curated by ChEMBL
LigandPNGBDBM50180683(CHEMBL3818720)
Affinity DataIC50:  80nMAssay Description:Inhibition of aromatase in human MCF7 cells using [1beta-3H]androstenedione as substrate measured after 1 hr by liquid scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Central University Of Punjab

Curated by ChEMBL
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)
Affinity DataIC50:  84nMAssay Description:Inhibition of cKit (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Central University Of Punjab

Curated by ChEMBL
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)
Affinity DataIC50:  179nMAssay Description:Inhibition of c-MET (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetEstrogen receptor(Homo sapiens (Human))
Central University Of Punjab

Curated by ChEMBL
LigandPNGBDBM50294185(CHEMBL4168369)
Affinity DataIC50:  192nMAssay Description:Displacement of fluoromone TM from recombinant human ERalpha after 2 hrs by fluorescence polarization analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Central University Of Punjab

Curated by ChEMBL
LigandPNGBDBM50294176(CHEMBL4164124)
Affinity DataIC50:  202nMAssay Description:Displacement of fluoromone TM from recombinant human ERalpha after 2 hrs by fluorescence polarization analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Central University Of Punjab

Curated by ChEMBL
LigandPNGBDBM50294179(CHEMBL4168602)
Affinity DataIC50:  259nMAssay Description:Displacement of fluoromone TM from recombinant human ERalpha after 2 hrs by fluorescence polarization analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Central University Of Punjab

Curated by ChEMBL
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)
Affinity DataIC50:  283nMAssay Description:Inhibition of EGFR (unknown origin)More data for this Ligand-Target Pair
TargetSulfotransferase 1A1(Rattus norvegicus)TBA
LigandPNGBDBM23420(7,4′-Dihydroxy-isoflavone (3a) | 7-hydroxy-3...)
Affinity DataIC50:  290nMAssay Description:Inhibition of rat liver SULT1A1-mediated oestradiol sulfonation incubated for 20 minsMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetSulfotransferase 1A1(Rattus norvegicus)TBA
LigandPNGBDBM19459(5,7-dihydroxy-3-(4-hydroxyphenyl)-4H-chromen-4-one...)
Affinity DataIC50:  290nMAssay Description:Inhibition of rat liver SULT1A1-mediated oestradiol sulfonation incubated for 20 minsMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetSulfotransferase 1A1(Rattus norvegicus)TBA
LigandPNGBDBM7460(2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-4H-chrome...)
Affinity DataIC50:  290nMAssay Description:Inhibition of rat liver SULT1A1-mediated oestradiol sulfonation incubated for 20 minsMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetSulfotransferase 1A1(Rattus norvegicus)TBA
LigandPNGBDBM7462(3,5,7-trihydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-...)
Affinity DataIC50:  290nMAssay Description:Inhibition of rat liver SULT1A1-mediated oestradiol sulfonation incubated for 20 minsMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetEstrogen receptor(Homo sapiens (Human))
Central University Of Punjab

Curated by ChEMBL
LigandPNGBDBM50294180(CHEMBL4164944)
Affinity DataIC50:  300nMAssay Description:Displacement of fluoromone TM from recombinant human ERalpha after 2 hrs by fluorescence polarization analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteryl-sulfatase(Homo sapiens (Human))TBA
LigandPNGBDBM50188234(CHEMBL269221)
Affinity DataIC50:  380nMAssay Description:Inhibition of sulphatase in human MCF7 cells assessed as inhibition of E1-STS activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Central University Of Punjab

Curated by ChEMBL
LigandPNGBDBM50294177(CHEMBL4170073)
Affinity DataIC50:  387nMAssay Description:Displacement of fluoromone TM from recombinant human ERalpha after 2 hrs by fluorescence polarization analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor alpha(Bos taurus)TBA
LigandPNGBDBM50610463(CHEBI:67889 | NYASOL)
Affinity DataIC50:  400nMAssay Description:Displacement of [3H]-17beta-estradiol from bovine uterine estrogen receptor by competitive binding assayMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetEstrogen receptor(Homo sapiens (Human))
Central University Of Punjab

Curated by ChEMBL
LigandPNGBDBM50294183(CHEMBL4171721)
Affinity DataIC50:  539nMAssay Description:Displacement of fluoromone TM from recombinant human ERalpha after 2 hrs by fluorescence polarization analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
Central University Of Punjab

Curated by ChEMBL
LigandPNGBDBM50513256(CHEMBL4442995)
Affinity DataIC50:  620nMAssay Description:Inhibition of P-gp in HEK293/ABCB1 cells assessed as potentiation of doxorubicin-induced cytotoxicity by measuring doxorubicin IC50 at 1 uM incubated...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Central University Of Punjab

Curated by ChEMBL
LigandPNGBDBM50340677((5-fluorouracil)5-Fluoro-1H-pyrimidine-2,4-dione |...)
Affinity DataIC50:  630nMAssay Description:Inhibition of human recombinant aromatase expressed in baculovirus insect cell using 7-methoxy-trifluoromethyl coumarin (MFC) as substrate preincubat...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
Central University Of Punjab

Curated by ChEMBL
LigandPNGBDBM50513257(CHEMBL4215931)
Affinity DataIC50:  700nMAssay Description:Inhibition of P-gp in human NCI-H460/R cells assessed as potentiation of doxorubicin-induced cytotoxicity by measuring reduction in doxorubicin IC50 ...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central University Of Punjab

Curated by ChEMBL
LigandPNGBDBM50587903(CHEMBL5206722)
Affinity DataIC50:  910nMAssay Description:Inhibition of PTP1B (unknown origin) by SpectraMax 340 microplate reader AnalysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
Central University Of Punjab

Curated by ChEMBL
LigandPNGBDBM50513256(CHEMBL4442995)
Affinity DataIC50:  920nMAssay Description:Inhibition of P-gp in HEK293/ABCB1 cells assessed as potentiation of cisplatin-induced cytotoxicity by measuring cisplatin IC50 at 2 uM incubated for...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Central University Of Punjab

Curated by ChEMBL
LigandPNGBDBM23419((2S)-5,7-dihydroxy-2-(4-hydroxyphenyl)-3,4-dihydro...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of aromatase (unknown origin) preincubated for 10 mins in presence of NADPH generating system followed by addition of dibenzylfluorescein ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
Central University Of Punjab

Curated by ChEMBL
LigandPNGBDBM50367247(QUININE | Quinamm | Quinsan | cid_3034034)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition of P-gp-mediated Rhodamine-123 efflux in human MCF-7/DOX cells assessed as Rhodamine-123 accumulation preincubated for 15 mins followed by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central University Of Punjab

Curated by ChEMBL
LigandPNGBDBM50587900(CHEMBL5190487)
Affinity DataIC50:  1.75E+3nMAssay Description:Inhibition of PTP1B (unknown origin) by SpectraMax 340 microplate reader AnalysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central University Of Punjab

Curated by ChEMBL
LigandPNGBDBM50587902(CHEMBL5185543)
Affinity DataIC50:  2.05E+3nMAssay Description:Inhibition of PTP1B (unknown origin) by SpectraMax 340 microplate reader AnalysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central University Of Punjab

Curated by ChEMBL
LigandPNGBDBM50236238((3alpha,5beta)-3-hydroxycholan-24-oic acid | 3alph...)
Affinity DataIC50:  2.71E+3nMAssay Description:Inhibition of PTP1B (unknown origin) by SpectraMax 340 microplate reader AnalysisMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central University Of Punjab

Curated by ChEMBL
LigandPNGBDBM50346601(NSC-114945 | OLEANOLIC_ACID | Oleanolic acid | Ole...)
Affinity DataIC50:  2.95E+3nMAssay Description:Inhibition of PTP1B (unknown origin) by SpectraMax 340 microplate reader AnalysisMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Homo sapiens (Human))
Central University Of Punjab

Curated by ChEMBL
LigandPNGBDBM50346601(NSC-114945 | OLEANOLIC_ACID | Oleanolic acid | Ole...)
Affinity DataIC50:  2.95E+3nMAssay Description:Inhibition of TCPTP (unknown origin) by SpectraMax 340 microplate reader AnalysisMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetTubulin beta chain(Sus scrofa)
Central University Of Punjab

Curated by ChEMBL
LigandPNGBDBM50587899(CHEMBL5190025)
Affinity DataIC50:  3.40E+3nMAssay Description:Inhibition of pig brain tubulin polymerization by spectrometric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
Displayed 1 to 50 (of 89 total ) | Next | Last >>
Jump to: