Affinity DataIC50: 0.0600nMAssay Description:Inhibition of estrone sulfatase in homogeneous rat mammary tumorsMore data for this Ligand-Target Pair
Affinity DataIC50: 0.120nMAssay Description:Inhibition of estrone sulfatase in human MCF7 cell microsomesMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Central University Of Punjab
Curated by ChEMBL
Central University Of Punjab
Curated by ChEMBL
Affinity DataIC50: <1nMAssay Description:Inhibition of SYK (unknown origin)More data for this Ligand-Target Pair
TargetTyrosine-protein kinase Lyn(Homo sapiens (Human))
Central University Of Punjab
Curated by ChEMBL
Central University Of Punjab
Curated by ChEMBL
Affinity DataIC50: <1nMAssay Description:Inhibition of Lyn (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of placental sulphatase (unknown origin)More data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Central University Of Punjab
Curated by ChEMBL
Central University Of Punjab
Curated by ChEMBL
Affinity DataIC50: <1nMAssay Description:Inhibition of FLT3 (unknown origin)More data for this Ligand-Target Pair
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Central University Of Punjab
Curated by ChEMBL
Central University Of Punjab
Curated by ChEMBL
Affinity DataIC50: <1nMAssay Description:Inhibition of ALK (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: <1nMAssay Description:Inhibition of Aurora A(unknown origin)More data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Central University Of Punjab
Curated by ChEMBL
Central University Of Punjab
Curated by ChEMBL
Affinity DataIC50: 1.80nMAssay Description:Inhibition of FGFR2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 2.30nMAssay Description:Inhibition of human recombinant aromatase expressed in baculovirus insect cell using 7-methoxy-trifluoromethyl coumarin (MFC) as substrate preincubat...More data for this Ligand-Target Pair
Affinity DataIC50: 2.80nMAssay Description:Inhibition of human recombinant aromatase expressed in baculovirus insect cell using 7-methoxy-trifluoromethyl coumarin (MFC) as substrate preincubat...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Central University Of Punjab
Curated by ChEMBL
Central University Of Punjab
Curated by ChEMBL
Affinity DataIC50: 4.5nMAssay Description:Inhibition of BRAF V599E mutant(unknown origin)More data for this Ligand-Target Pair
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Central University Of Punjab
Curated by ChEMBL
Central University Of Punjab
Curated by ChEMBL
Affinity DataIC50: 4.60nMAssay Description:Inhibition of AKT1 (unknown origin)More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Central University Of Punjab
Curated by ChEMBL
Central University Of Punjab
Curated by ChEMBL
Affinity DataIC50: 14nMAssay Description:Inhibition of BRAF (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 33nMAssay Description:Displacement of fluoromone TM from recombinant human ERalpha after 2 hrs by fluorescence polarization analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 47nMAssay Description:Displacement of fluoromone TM from recombinant human ERalpha after 2 hrs by fluorescence polarization analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 51nMAssay Description:Inhibition of human placental microsomal aromatase using testosterone as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 60nMAssay Description:Displacement of [3H]-17beta-estradiol from bovine uterine estrogen receptor by competitive binding assayMore data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 74nMAssay Description:Displacement of fluoromone TM from recombinant human ERalpha after 2 hrs by fluorescence polarization analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 77nMAssay Description:Displacement of fluoromone TM from recombinant human ERalpha after 2 hrs by fluorescence polarization analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 80nMAssay Description:Displacement of fluoromone TM from recombinant human ERalpha after 2 hrs by fluorescence polarization analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 80nMAssay Description:Inhibition of aromatase in human MCF7 cells using [1beta-3H]androstenedione as substrate measured after 1 hr by liquid scintillation counting methodMore data for this Ligand-Target Pair
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Central University Of Punjab
Curated by ChEMBL
Central University Of Punjab
Curated by ChEMBL
Affinity DataIC50: 84nMAssay Description:Inhibition of cKit (unknown origin)More data for this Ligand-Target Pair
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Central University Of Punjab
Curated by ChEMBL
Central University Of Punjab
Curated by ChEMBL
Affinity DataIC50: 179nMAssay Description:Inhibition of c-MET (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 192nMAssay Description:Displacement of fluoromone TM from recombinant human ERalpha after 2 hrs by fluorescence polarization analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 202nMAssay Description:Displacement of fluoromone TM from recombinant human ERalpha after 2 hrs by fluorescence polarization analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 259nMAssay Description:Displacement of fluoromone TM from recombinant human ERalpha after 2 hrs by fluorescence polarization analysisMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Central University Of Punjab
Curated by ChEMBL
Central University Of Punjab
Curated by ChEMBL
Affinity DataIC50: 283nMAssay Description:Inhibition of EGFR (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 290nMAssay Description:Inhibition of rat liver SULT1A1-mediated oestradiol sulfonation incubated for 20 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 290nMAssay Description:Inhibition of rat liver SULT1A1-mediated oestradiol sulfonation incubated for 20 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 290nMAssay Description:Inhibition of rat liver SULT1A1-mediated oestradiol sulfonation incubated for 20 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 290nMAssay Description:Inhibition of rat liver SULT1A1-mediated oestradiol sulfonation incubated for 20 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 300nMAssay Description:Displacement of fluoromone TM from recombinant human ERalpha after 2 hrs by fluorescence polarization analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 380nMAssay Description:Inhibition of sulphatase in human MCF7 cells assessed as inhibition of E1-STS activityMore data for this Ligand-Target Pair
Affinity DataIC50: 387nMAssay Description:Displacement of fluoromone TM from recombinant human ERalpha after 2 hrs by fluorescence polarization analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 400nMAssay Description:Displacement of [3H]-17beta-estradiol from bovine uterine estrogen receptor by competitive binding assayMore data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 539nMAssay Description:Displacement of fluoromone TM from recombinant human ERalpha after 2 hrs by fluorescence polarization analysisMore data for this Ligand-Target Pair
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
Central University Of Punjab
Curated by ChEMBL
Central University Of Punjab
Curated by ChEMBL
Affinity DataIC50: 620nMAssay Description:Inhibition of P-gp in HEK293/ABCB1 cells assessed as potentiation of doxorubicin-induced cytotoxicity by measuring doxorubicin IC50 at 1 uM incubated...More data for this Ligand-Target Pair
Affinity DataIC50: 630nMAssay Description:Inhibition of human recombinant aromatase expressed in baculovirus insect cell using 7-methoxy-trifluoromethyl coumarin (MFC) as substrate preincubat...More data for this Ligand-Target Pair
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
Central University Of Punjab
Curated by ChEMBL
Central University Of Punjab
Curated by ChEMBL
Affinity DataIC50: 700nMAssay Description:Inhibition of P-gp in human NCI-H460/R cells assessed as potentiation of doxorubicin-induced cytotoxicity by measuring reduction in doxorubicin IC50 ...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central University Of Punjab
Curated by ChEMBL
Central University Of Punjab
Curated by ChEMBL
Affinity DataIC50: 910nMAssay Description:Inhibition of PTP1B (unknown origin) by SpectraMax 340 microplate reader AnalysisMore data for this Ligand-Target Pair
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
Central University Of Punjab
Curated by ChEMBL
Central University Of Punjab
Curated by ChEMBL
Affinity DataIC50: 920nMAssay Description:Inhibition of P-gp in HEK293/ABCB1 cells assessed as potentiation of cisplatin-induced cytotoxicity by measuring cisplatin IC50 at 2 uM incubated for...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of aromatase (unknown origin) preincubated for 10 mins in presence of NADPH generating system followed by addition of dibenzylfluorescein ...More data for this Ligand-Target Pair
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
Central University Of Punjab
Curated by ChEMBL
Central University Of Punjab
Curated by ChEMBL
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of P-gp-mediated Rhodamine-123 efflux in human MCF-7/DOX cells assessed as Rhodamine-123 accumulation preincubated for 15 mins followed by...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central University Of Punjab
Curated by ChEMBL
Central University Of Punjab
Curated by ChEMBL
Affinity DataIC50: 1.75E+3nMAssay Description:Inhibition of PTP1B (unknown origin) by SpectraMax 340 microplate reader AnalysisMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central University Of Punjab
Curated by ChEMBL
Central University Of Punjab
Curated by ChEMBL
Affinity DataIC50: 2.05E+3nMAssay Description:Inhibition of PTP1B (unknown origin) by SpectraMax 340 microplate reader AnalysisMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central University Of Punjab
Curated by ChEMBL
Central University Of Punjab
Curated by ChEMBL
Affinity DataIC50: 2.71E+3nMAssay Description:Inhibition of PTP1B (unknown origin) by SpectraMax 340 microplate reader AnalysisMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central University Of Punjab
Curated by ChEMBL
Central University Of Punjab
Curated by ChEMBL
Affinity DataIC50: 2.95E+3nMAssay Description:Inhibition of PTP1B (unknown origin) by SpectraMax 340 microplate reader AnalysisMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 2(Homo sapiens (Human))
Central University Of Punjab
Curated by ChEMBL
Central University Of Punjab
Curated by ChEMBL
Affinity DataIC50: 2.95E+3nMAssay Description:Inhibition of TCPTP (unknown origin) by SpectraMax 340 microplate reader AnalysisMore data for this Ligand-Target Pair
Affinity DataIC50: 3.40E+3nMAssay Description:Inhibition of pig brain tubulin polymerization by spectrometric methodMore data for this Ligand-Target Pair