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Found 39 with Last Name = 'jakobsen' and Initial = 'p'
TargetSolute carrier family 15 member 1(Homo sapiens (Human))
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50418932(CHEMBL1807354)
Affinity DataKi:  4.68E+7nMAssay Description:Binding affinity to PEPT1 in human Caco2 cells assessed as inhibition of [14C]Gly-Sar apical uptake after 5 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSolute carrier family 15 member 1(Homo sapiens (Human))
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50418933(CHEMBL1807356)
Affinity DataKi:  1.23E+8nMAssay Description:Binding affinity to PEPT1 in human Caco2 cells assessed as inhibition of [14C]Gly-Sar apical uptake after 5 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSolute carrier family 15 member 1(Homo sapiens (Human))
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50418934(CHEMBL1807357)
Affinity DataKi:  2.45E+8nMAssay Description:Binding affinity to PEPT1 in human Caco2 cells assessed as inhibition of [14C]Gly-Sar apical uptake after 5 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSolute carrier family 15 member 1(Homo sapiens (Human))
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50418935(CHEMBL1807353)
Affinity DataKi:  2.51E+8nMAssay Description:Binding affinity to PEPT1 in human Caco2 cells assessed as inhibition of [14C]Gly-Sar apical uptake after 5 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSolute carrier family 15 member 1(Homo sapiens (Human))
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50418931(CHEMBL1807351)
Affinity DataKi:  2.57E+8nMAssay Description:Binding affinity to PEPT1 in human Caco2 cells assessed as inhibition of [14C]Gly-Sar apical uptake after 5 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSolute carrier family 15 member 1(Homo sapiens (Human))
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50418936(CHEMBL1807352)
Affinity DataKi:  3.24E+8nMAssay Description:Binding affinity to PEPT1 in human Caco2 cells assessed as inhibition of [14C]Gly-Sar apical uptake after 5 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-6-phosphatase catalytic subunit 1(Homo sapiens (Human))
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50103118(CHEMBL66059 | N,N-Dibenzyl-N'-[1-(5-chloro-thiophe...)
Affinity DataIC50:  170nMAssay Description:Compound was evaluated for inhibition of Glucose-6-Phosphatase from Triton X-100 disrupted pig liver microsomes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-6-phosphatase catalytic subunit 1(Homo sapiens (Human))
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50103125(CHEMBL69115 | N,N-Dibenzyl-N'-[1-(4-methoxy-phenyl...)
Affinity DataIC50:  220nMAssay Description:Compound was evaluated for inhibition of Glucose-6-Phosphatase from Triton X-100 disrupted pig liver microsomes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-6-phosphatase catalytic subunit 1(Homo sapiens (Human))
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50103111(CHEMBL69665 | N,N-Dibenzyl-N'-[1-(4-chloro-phenyl)...)
Affinity DataIC50:  240nMAssay Description:Compound was evaluated for inhibition of Glucose-6-Phosphatase from Triton X-100 disrupted pig liver microsomes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-6-phosphatase catalytic subunit 1(Homo sapiens (Human))
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50103119(CHEMBL302504 | N,N-Dibenzyl-N'-[1-(5-ethyl-furan-2...)
Affinity DataIC50:  330nMAssay Description:Compound was evaluated for inhibition of Glucose-6-Phosphatase from Triton X-100 disrupted pig liver microsomes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-6-phosphatase catalytic subunit 1(Homo sapiens (Human))
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50103107(CHEMBL65842 | N,N-Dibenzyl-N'-[1-(3-methoxy-phenyl...)
Affinity DataIC50:  700nMAssay Description:Compound was evaluated for inhibition of Glucose-6-Phosphatase from Triton X-100 disrupted pig liver microsomes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-6-phosphatase catalytic subunit 1(Homo sapiens (Human))
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50103128(CHEMBL68984 | N,N-Dibenzyl-N'-[1-furan-2-yl-meth-(...)
Affinity DataIC50:  1.10E+3nMAssay Description:Compound was evaluated for inhibition of Glucose-6-Phosphatase from Triton X-100 disrupted pig liver microsomes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-6-phosphatase catalytic subunit 1(Homo sapiens (Human))
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50103106(CHEMBL69480 | N,N-Dibenzyl-N'-[1-thiophen-2-yl-met...)
Affinity DataIC50:  1.50E+3nMAssay Description:Compound was evaluated for inhibition of Glucose-6-Phosphatase from Triton X-100 disrupted pig liver microsomes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-6-phosphatase catalytic subunit 1(Homo sapiens (Human))
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50103122(CHEMBL69334 | N,N-Dibenzyl-N'-[1-phenyl-meth-(E)-y...)
Affinity DataIC50:  1.50E+3nMAssay Description:Compound was evaluated for inhibition of Glucose-6-Phosphatase from Triton X-100 disrupted pig liver microsomes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-6-phosphatase catalytic subunit 1(Homo sapiens (Human))
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50103110(CHEMBL305258 | N,N-Dibenzyl-N'-[1-(3,4-dichloro-ph...)
Affinity DataIC50:  2.00E+3nMAssay Description:Compound was evaluated for inhibition of Glucose-6-Phosphatase from Triton X-100 disrupted pig liver microsomes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-6-phosphatase catalytic subunit 1(Homo sapiens (Human))
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50103114(CHEMBL69541 | N,N-Dibenzyl-N'-[1-cyclohexyl-meth-(...)
Affinity DataIC50:  2.40E+3nMAssay Description:Compound was evaluated for inhibition of Glucose-6-Phosphatase from Triton X-100 disrupted pig liver microsomes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-6-phosphatase catalytic subunit 1(Homo sapiens (Human))
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50103115(4-(Dibenzyl-hydrazonomethyl)-phenol | CHEMBL70032)
Affinity DataIC50:  2.40E+3nMAssay Description:Compound was evaluated for inhibition of Glucose-6-Phosphatase from Triton X-100 disrupted pig liver microsomes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-6-phosphatase catalytic subunit 1(Homo sapiens (Human))
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50103126(CHEMBL68011 | N,N-Dibenzyl-N'-[1-pyridin-3-yl-meth...)
Affinity DataIC50:  3.70E+3nMAssay Description:Compound was evaluated for inhibition of Glucose-6-Phosphatase from Triton X-100 disrupted pig liver microsomes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50030630((RS)-1-aminoindan-1,5-dicarboxylic acid | 1-Amino-...)
Affinity DataIC50:  7.00E+3nMAssay Description:Ability to inhibit mGluR1-alpha-mediated PI (phospho inosotol) hydrolysis was determined at BHK cells at 100 Micro M ConcentrationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-6-phosphatase catalytic subunit 1(Homo sapiens (Human))
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50103120(CHEMBL69497 | N,N-Dibenzyl-N'-[1-pyridin-2-yl-meth...)
Affinity DataIC50:  1.00E+4nMAssay Description:Compound was evaluated for inhibition of Glucose-6-Phosphatase from Triton X-100 disrupted pig liver microsomes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-6-phosphatase catalytic subunit 1(Homo sapiens (Human))
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50103124(CHEMBL67272 | [5-(Dibenzyl-hydrazonomethyl)-furan-...)
Affinity DataIC50:  1.60E+4nMAssay Description:Compound was evaluated for inhibition of Glucose-6-Phosphatase from Triton X-100 disrupted pig liver microsomes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-6-phosphatase catalytic subunit 1(Homo sapiens (Human))
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50103112(CHEMBL71650 | N,N-Dibenzyl-N'-[1-pyridin-4-yl-meth...)
Affinity DataIC50:  1.70E+4nMAssay Description:Compound was evaluated for inhibition of Glucose-6-Phosphatase from Triton X-100 disrupted pig liver microsomes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-6-phosphatase catalytic subunit 1(Homo sapiens (Human))
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50103121(CHEMBL419070 | N,N-Dibenzyl-N'-[1-phenyl-eth-(E)-y...)
Affinity DataIC50:  2.50E+4nMAssay Description:Compound was evaluated for inhibition of Glucose-6-Phosphatase from Triton X-100 disrupted pig liver microsomes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-6-phosphatase catalytic subunit 1(Homo sapiens (Human))
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50103109(CHEMBL66774 | N,N-Dibenzyl-N'-[3,4-dihydro-2H-naph...)
Affinity DataIC50:  2.50E+4nMAssay Description:Compound was evaluated for inhibition of Glucose-6-Phosphatase from Triton X-100 disrupted pig liver microsomes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50030628((S)-4C3HPG | 4-(Amino-carboxy-methyl)-2-hydroxy-be...)
Affinity DataIC50:  4.00E+4nMAssay Description:Ability to inhibit mGluR1-alpha-mediated PI (phospho inosotol) hydrolysis was determined at BHK cells at 100 Micro M ConcentrationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50030628((S)-4C3HPG | 4-(Amino-carboxy-methyl)-2-hydroxy-be...)
Affinity DataIC50:  4.80E+4nMAssay Description:Ability to inhibit mGluR2-alpha induced cAMP formation was determined at BHK cells at 100 Micro M ConcentrationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-6-phosphatase catalytic subunit 1(Homo sapiens (Human))
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50103116(CHEMBL68981 | N,N-Dibenzyl-N'-[6-methoxy-3,4-dihyd...)
Affinity DataIC50: >5.00E+4nMAssay Description:Compound was evaluated for inhibition of Glucose-6-Phosphatase from Triton X-100 disrupted pig liver microsomes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50030629((R,S)-4-Carboxy-3-hydroxyphenylglycine | (S)-4CPG ...)
Affinity DataIC50:  6.50E+4nMAssay Description:Ability to inhibit mGluR1-alpha-mediated PI (phospho inosotol) hydrolysis was determined at BHK cells at 100 Micro M ConcentrationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-6-phosphatase catalytic subunit 1(Homo sapiens (Human))
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50103127(CHEMBL69742 | N,N-Dibenzyl-N'-[1-(5-nitro-furan-2-...)
Affinity DataIC50: >1.00E+5nMAssay Description:Compound was evaluated for inhibition of Glucose-6-Phosphatase from Triton X-100 disrupted pig liver microsomes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-6-phosphatase catalytic subunit 1(Homo sapiens (Human))
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50103123(CHEMBL68153 | N,N-Dibenzyl-N'-[2-phenyl-eth-(E)-yl...)
Affinity DataIC50: >1.00E+5nMAssay Description:Compound was evaluated for inhibition of Glucose-6-Phosphatase from Triton X-100 disrupted pig liver microsomes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-6-phosphatase catalytic subunit 1(Homo sapiens (Human))
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50103117(CHEMBL302496 | N,N-Dibenzyl-N'-[1-(3,5-dichloro-ph...)
Affinity DataIC50: >1.00E+5nMAssay Description:Compound was evaluated for inhibition of Glucose-6-Phosphatase from Triton X-100 disrupted pig liver microsomes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-6-phosphatase catalytic subunit 1(Homo sapiens (Human))
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50103108(CHEMBL304503 | N,N-Dibenzyl-N'-[1-(2-methoxy-pheny...)
Affinity DataIC50: >1.00E+5nMAssay Description:Compound was evaluated for inhibition of Glucose-6-Phosphatase from Triton X-100 disrupted pig liver microsomes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-6-phosphatase catalytic subunit 1(Homo sapiens (Human))
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50103113(CHEMBL69758 | [4-(Dibenzyl-hydrazonomethyl)-phenyl...)
Affinity DataIC50:  1.00E+5nMAssay Description:Compound was evaluated for inhibition of Glucose-6-Phosphatase from Triton X-100 disrupted pig liver microsomes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50030627((+-)-MCPG | (R,S)-alpha-Methyl-4-carboxyphenylglyc...)
Affinity DataIC50:  1.55E+5nMAssay Description:Ability to inhibit mGluR1-alpha-mediated PI (phospho inosotol) hydrolysis was determined at BHK cells at 100 Micro M ConcentrationMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50030627((+-)-MCPG | (R,S)-alpha-Methyl-4-carboxyphenylglyc...)
Affinity DataIC50:  3.40E+5nMAssay Description:Ability to inhibit mGluR2-alpha induced cAMP formation was determined at BHK cells at 100 Micro M ConcentrationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50030629((R,S)-4-Carboxy-3-hydroxyphenylglycine | (S)-4CPG ...)
Affinity DataIC50:  5.77E+5nMAssay Description:Ability to inhibit mGluR2-alpha induced cAMP formation was determined at BHK cells at 100 Micro M ConcentrationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50030627((+-)-MCPG | (R,S)-alpha-Methyl-4-carboxyphenylglyc...)
Affinity DataIC50: >1.00E+6nMAssay Description:Ability to inhibit mGluR4-alpha induced cAMP formation was determined at BHK cells at 100 Micro M ConcentrationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50030629((R,S)-4-Carboxy-3-hydroxyphenylglycine | (S)-4CPG ...)
Affinity DataIC50: >1.00E+6nMAssay Description:Ability to inhibit mGluR4-alpha induced cAMP formation was determined at BHK cells at 100 Micro M ConcentrationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50030628((S)-4C3HPG | 4-(Amino-carboxy-methyl)-2-hydroxy-be...)
Affinity DataIC50: >1.00E+6nMAssay Description:Ability to inhibit mGluR4-alpha induced cAMP formation was determined at BHK cells at 100 Micro M ConcentrationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed