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Found 1403 with Last Name = 'jinkerson' and Initial = 'tk'
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM143965(US8969325, 166)
Affinity DataIC50:  1nMAssay Description:The cDNA for human TRPV1 (hTRPV1) was isolated by reverse transcriptase-polymerase chain reaction (RT-PCR) from human small intestine poly A+ RNA sup...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM143964(US8969325, 165)
Affinity DataIC50:  3nMAssay Description:The cDNA for human TRPV1 (hTRPV1) was isolated by reverse transcriptase-polymerase chain reaction (RT-PCR) from human small intestine poly A+ RNA sup...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM50319456(1-(1H-indazol-4-yl)-3-((2-(piperidin-1-yl)-6-(trif...)
Affinity DataIC50:  3.5nMAssay Description:Antagonist activity at human TRPV1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM143829(US8969325, 30)
Affinity DataIC50:  4nMAssay Description:The cDNA for human TRPV1 (hTRPV1) was isolated by reverse transcriptase-polymerase chain reaction (RT-PCR) from human small intestine poly A+ RNA sup...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM143834(US8969325, 35)
Affinity DataIC50:  4nMAssay Description:The cDNA for human TRPV1 (hTRPV1) was isolated by reverse transcriptase-polymerase chain reaction (RT-PCR) from human small intestine poly A+ RNA sup...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM50319471(1-(2-(3,3-dimethylbutyl)-4-(trifluoromethyl)benzyl...)
Affinity DataIC50:  4.30nMAssay Description:Antagonist activity at human TRPV1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM144122(US8969325, 323)
Affinity DataIC50:  4.5nMAssay Description:The cDNA for human TRPV1 (hTRPV1) was isolated by reverse transcriptase-polymerase chain reaction (RT-PCR) from human small intestine poly A+ RNA sup...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM50319465(1-((2-(3,3-dimethylbutyl)-6-(trifluoromethyl)pyrid...)
Affinity DataIC50:  5nMAssay Description:Antagonist activity at human TRPV1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM143966(US8969325, 167)
Affinity DataIC50:  5nMAssay Description:The cDNA for human TRPV1 (hTRPV1) was isolated by reverse transcriptase-polymerase chain reaction (RT-PCR) from human small intestine poly A+ RNA sup...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C virus (HCV genotype 1a, isolate H))
Abbvie

US Patent
LigandPNGBDBM186332(US9163017, 6)
Affinity DataIC50:  5.05nMAssay Description:The inhibitory effects of the compounds of the invention on HCV replication can be determined by measuring activity of the luciferase reporter gene. ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C virus (HCV genotype 1a, isolate H))
Abbvie

US Patent
LigandPNGBDBM186333(US9163017, 7)
Affinity DataIC50:  5.05nMAssay Description:The inhibitory effects of the compounds of the invention on HCV replication can be determined by measuring activity of the luciferase reporter gene. ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C virus (HCV genotype 1a, isolate H))
Abbvie

US Patent
LigandPNGBDBM186334(US9163017, 8)
Affinity DataIC50:  5.05nMAssay Description:The inhibitory effects of the compounds of the invention on HCV replication can be determined by measuring activity of the luciferase reporter gene. ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C virus (HCV genotype 1a, isolate H))
Abbvie

US Patent
LigandPNGBDBM186335(US9163017, 9)
Affinity DataIC50:  5.05nMAssay Description:The inhibitory effects of the compounds of the invention on HCV replication can be determined by measuring activity of the luciferase reporter gene. ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C virus (HCV genotype 1a, isolate H))
Abbvie

US Patent
LigandPNGBDBM186336(US9163017, 10)
Affinity DataIC50:  5.05nMAssay Description:The inhibitory effects of the compounds of the invention on HCV replication can be determined by measuring activity of the luciferase reporter gene. ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C virus (HCV genotype 1a, isolate H))
Abbvie

US Patent
LigandPNGBDBM186337(US9163017, 11)
Affinity DataIC50:  5.05nMAssay Description:The inhibitory effects of the compounds of the invention on HCV replication can be determined by measuring activity of the luciferase reporter gene. ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C virus (HCV genotype 1a, isolate H))
Abbvie

US Patent
LigandPNGBDBM186338(US9163017, 12)
Affinity DataIC50:  5.05nMAssay Description:The inhibitory effects of the compounds of the invention on HCV replication can be determined by measuring activity of the luciferase reporter gene. ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C virus (HCV genotype 1a, isolate H))
Abbvie

US Patent
LigandPNGBDBM186339(US9163017, 13)
Affinity DataIC50:  5.05nMAssay Description:The inhibitory effects of the compounds of the invention on HCV replication can be determined by measuring activity of the luciferase reporter gene. ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C virus (HCV genotype 1a, isolate H))
Abbvie

US Patent
LigandPNGBDBM186342(US9163017, 16)
Affinity DataIC50:  5.05nMAssay Description:The inhibitory effects of the compounds of the invention on HCV replication can be determined by measuring activity of the luciferase reporter gene. ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C virus (HCV genotype 1a, isolate H))
Abbvie

US Patent
LigandPNGBDBM186343(US9163017, 17)
Affinity DataIC50:  5.05nMAssay Description:The inhibitory effects of the compounds of the invention on HCV replication can be determined by measuring activity of the luciferase reporter gene. ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C virus (HCV genotype 1a, isolate H))
Abbvie

US Patent
LigandPNGBDBM186331(US9163017, 5)
Affinity DataIC50:  5.05nMAssay Description:The inhibitory effects of the compounds of the invention on HCV replication can be determined by measuring activity of the luciferase reporter gene. ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C virus (HCV genotype 1a, isolate H))
Abbvie

US Patent
LigandPNGBDBM186324(US9163017, 3)
Affinity DataIC50:  5.05nMAssay Description:The inhibitory effects of the compounds of the invention on HCV replication can be determined by measuring activity of the luciferase reporter gene. ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C virus (HCV genotype 1a, isolate H))
Abbvie

US Patent
LigandPNGBDBM186318(US9163017, 2)
Affinity DataIC50:  5.05nMAssay Description:The inhibitory effects of the compounds of the invention on HCV replication can be determined by measuring activity of the luciferase reporter gene. ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM50319464(1-(1H-indazol-4-yl)-3-((2-(neopentyloxy)-6-(triflu...)
Affinity DataIC50:  6nMAssay Description:Antagonist activity at human TRPV1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM50319470(1-(2-(3-fluoro-3-methylbutyl)-4-(trifluoromethyl)b...)
Affinity DataIC50:  6nMAssay Description:Antagonist activity at human TRPV1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM143833(US8969325, 34)
Affinity DataIC50:  7nMAssay Description:The cDNA for human TRPV1 (hTRPV1) was isolated by reverse transcriptase-polymerase chain reaction (RT-PCR) from human small intestine poly A+ RNA sup...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM50319454(1-(2-(3,3-dimethylbutyl)-4-(trifluoromethyl)benzyl...)
Affinity DataIC50:  7nMpH: 5.5Assay Description:Antagonist activity at human TRPV1 expressed in HEK293 cells assessed as inhibition of capsaicin-induced effect at pH 5.5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM50319466(1-(1H-indazol-4-yl)-3-(2-(3-methoxypropyl)-4-(trif...)
Affinity DataIC50:  8nMAssay Description:Antagonist activity at human TRPV1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM143895(US8969325, 96)
Affinity DataIC50:  8nMAssay Description:The cDNA for human TRPV1 (hTRPV1) was isolated by reverse transcriptase-polymerase chain reaction (RT-PCR) from human small intestine poly A+ RNA sup...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM50319467(1-(1H-indazol-4-yl)-3-(2-phenethyl-4-(trifluoromet...)
Affinity DataIC50:  8nMAssay Description:Antagonist activity at human TRPV1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM143933(US8969325, 134)
Affinity DataIC50:  8nMAssay Description:The cDNA for human TRPV1 (hTRPV1) was isolated by reverse transcriptase-polymerase chain reaction (RT-PCR) from human small intestine poly A+ RNA sup...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM50319469(1-(1H-indazol-4-yl)-3-(2-isopropyl-4-(trifluoromet...)
Affinity DataIC50:  9nMAssay Description:Antagonist activity at human TRPV1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM50319461(1-(1H-indazol-4-yl)-3-((2-phenoxy-6-(trifluorometh...)
Affinity DataIC50:  9nMAssay Description:Antagonist activity at human TRPV1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM50319468(1-(1H-indazol-4-yl)-3-(2-phenoxy-4-(trifluoromethy...)
Affinity DataIC50:  9nMAssay Description:Antagonist activity at human TRPV1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM143818(US8969325, 19)
Affinity DataIC50:  10nMAssay Description:The cDNA for human TRPV1 (hTRPV1) was isolated by reverse transcriptase-polymerase chain reaction (RT-PCR) from human small intestine poly A+ RNA sup...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM143800(US8969325, 1)
Affinity DataIC50:  10nMAssay Description:The cDNA for human TRPV1 (hTRPV1) was isolated by reverse transcriptase-polymerase chain reaction (RT-PCR) from human small intestine poly A+ RNA sup...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM143885(US8969325, 86)
Affinity DataIC50:  10nMAssay Description:The cDNA for human TRPV1 (hTRPV1) was isolated by reverse transcriptase-polymerase chain reaction (RT-PCR) from human small intestine poly A+ RNA sup...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM143889(US8969325, 90)
Affinity DataIC50:  11nMAssay Description:The cDNA for human TRPV1 (hTRPV1) was isolated by reverse transcriptase-polymerase chain reaction (RT-PCR) from human small intestine poly A+ RNA sup...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM143939(US8969325, 140)
Affinity DataIC50:  11nMAssay Description:The cDNA for human TRPV1 (hTRPV1) was isolated by reverse transcriptase-polymerase chain reaction (RT-PCR) from human small intestine poly A+ RNA sup...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM143938(US8969325, 139)
Affinity DataIC50:  12nMAssay Description:The cDNA for human TRPV1 (hTRPV1) was isolated by reverse transcriptase-polymerase chain reaction (RT-PCR) from human small intestine poly A+ RNA sup...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM50319459(1-(1H-indazol-4-yl)-3-((2-morpholino-6-(trifluorom...)
Affinity DataIC50:  12nMAssay Description:Antagonist activity at human TRPV1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM144119(US8969325, 320)
Affinity DataIC50:  12nMAssay Description:The cDNA for human TRPV1 (hTRPV1) was isolated by reverse transcriptase-polymerase chain reaction (RT-PCR) from human small intestine poly A+ RNA sup...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM143827(US8969325, 28)
Affinity DataIC50:  12nMAssay Description:The cDNA for human TRPV1 (hTRPV1) was isolated by reverse transcriptase-polymerase chain reaction (RT-PCR) from human small intestine poly A+ RNA sup...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM143840(US8969325, 41)
Affinity DataIC50:  12nMAssay Description:The cDNA for human TRPV1 (hTRPV1) was isolated by reverse transcriptase-polymerase chain reaction (RT-PCR) from human small intestine poly A+ RNA sup...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM50319463(1-(1H-indazol-4-yl)-3-((2-(3-methoxypropyl)-6-(tri...)
Affinity DataIC50:  12nMAssay Description:Antagonist activity at human TRPV1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM144051(US8969325, 252)
Affinity DataIC50:  13nMAssay Description:The cDNA for human TRPV1 (hTRPV1) was isolated by reverse transcriptase-polymerase chain reaction (RT-PCR) from human small intestine poly A+ RNA sup...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM50319458(1-(1H-indazol-4-yl)-3-((6-phenyl-2-(piperidin-1-yl...)
Affinity DataIC50:  14nMAssay Description:Antagonist activity at human TRPV1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM143863(US8969325, 64)
Affinity DataIC50:  14nMAssay Description:The cDNA for human TRPV1 (hTRPV1) was isolated by reverse transcriptase-polymerase chain reaction (RT-PCR) from human small intestine poly A+ RNA sup...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM143838(US8969325, 39)
Affinity DataIC50:  14nMAssay Description:The cDNA for human TRPV1 (hTRPV1) was isolated by reverse transcriptase-polymerase chain reaction (RT-PCR) from human small intestine poly A+ RNA sup...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM143953(US8969325, 154)
Affinity DataIC50:  15nMAssay Description:The cDNA for human TRPV1 (hTRPV1) was isolated by reverse transcriptase-polymerase chain reaction (RT-PCR) from human small intestine poly A+ RNA sup...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM50319454(1-(2-(3,3-dimethylbutyl)-4-(trifluoromethyl)benzyl...)
Affinity DataIC50:  15nMAssay Description:Antagonist activity at human TRPV1 expressed in HEK293 cells assessed as inhibition of N-arachidonoyldopamine-induced effectMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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