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Found 107 with Last Name = 'jung' and Initial = 'je'
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM79800(5-(methylamino)-2-(1-naphthalenyl)-4-oxazolecarbon...)
Affinity DataKi:  100nMAssay Description:Inhibition of recombinant N-terminal His6-tagged human reticulocyte 12/15-lipoxygenase using arachidonic acid as substrate assessed as equilibrium co...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM56150((6E)-4-methyl-6-[5-(2-methylphenyl)-1,2-dihydropyr...)
Affinity DataKi:  1.00E+3nMAssay Description:Competitive inhibition of N-terminal His6-tagged human 12/15-LOX using arachidonic acid as substrate by Dixon plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM79800(5-(methylamino)-2-(1-naphthalenyl)-4-oxazolecarbon...)
Affinity DataKi:  1.20E+3nMAssay Description:Inhibition of recombinant N-terminal His6-tagged human reticulocyte 12/15-lipoxygenase using arachidonic acid as substrate assessed as equilibrium co...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50609365(CHEMBL5282123)
Affinity DataIC50:  3.70nMAssay Description:Inhibition of ENPP1 (unknown origin)More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Oryctolagus cuniculus (rabbit))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM22302(N-{2-[2-(1-benzofuran-2-yl)-1H-indol-3-yl]ethyl}-4...)
Affinity DataIC50:  21nMAssay Description:Inhibition of rabbit reticulocyte 12/15-lipoxygenaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50609356(CHEMBL5278177)
Affinity DataIC50:  32nMAssay Description:Inhibition of ENPP1 (unknown origin)More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
LigandPNGBDBM50609368(CHEMBL5287511)
Affinity DataIC50:  45nMAssay Description:Inhibition of ENPP1 (unknown origin)More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
LigandPNGBDBM50609362(CHEMBL5282991)
Affinity DataIC50:  48nMAssay Description:Inhibition of ENPP1 (unknown origin)More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM30770(2-(1-naphthalenyl)-5-(propylamino)-4-oxazolecarbon...)
Affinity DataIC50:  100nMAssay Description:Inhibition of recombinant N-terminal His6-tagged human reticulocyte 12/15-lipoxygenase using arachidonic acid as substrate by UV-vis spectrometric an...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM32020(4-[4-(3,4-dihydroxyphenyl)-2,3-dimethyl-butyl]pyro...)
Affinity DataIC50:  110nMAssay Description:Inhibition of human reticulocyte 12/15-lipoxygenase using arachidonic acid/linoleic acid as substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM44681(5-(ethylamino)-2-(1-naphthalenyl)-4-oxazolecarboni...)
Affinity DataIC50:  120nMAssay Description:Inhibition of recombinant N-terminal His6-tagged human reticulocyte 12/15-lipoxygenase using arachidonic acid as substrate by UV-vis spectrometric an...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50011748(CHEMBL3262919)
Affinity DataIC50:  120nMAssay Description:Inhibition of recombinant N-terminal His6-tagged human reticulocyte 12/15-lipoxygenase using arachidonic acid as substrate by UV-vis spectrometric an...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50609367(CHEMBL5279977)
Affinity DataIC50:  164nMAssay Description:Inhibition of ENPP1 (unknown origin)More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
LigandPNGBDBM50609359(CHEMBL5280052)
Affinity DataIC50:  171nMAssay Description:Inhibition of ENPP1 (unknown origin)More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM79800(5-(methylamino)-2-(1-naphthalenyl)-4-oxazolecarbon...)
Affinity DataIC50:  200nMAssay Description:Inhibition of N-terminal His6-tagged human 12/15-LOX using arachidonic acid as substrate by UV-visible spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM79800(5-(methylamino)-2-(1-naphthalenyl)-4-oxazolecarbon...)
Affinity DataIC50:  200nMAssay Description:Inhibition of recombinant N-terminal His6-tagged human reticulocyte 12/15-lipoxygenase using arachidonic acid as substrate by UV-vis spectrometric an...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50609366(CHEMBL5287838)
Affinity DataIC50:  236nMAssay Description:Inhibition of ENPP1 (unknown origin)More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50011749(CHEMBL3262920)
Affinity DataIC50:  300nMAssay Description:Inhibition of recombinant N-terminal His6-tagged human reticulocyte 12/15-lipoxygenase using arachidonic acid as substrate by UV-vis spectrometric an...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50609355(CHEMBL5276377)
Affinity DataIC50:  326nMAssay Description:Inhibition of ENPP1 (unknown origin)More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
LigandPNGBDBM50609360(CHEMBL5272310)
Affinity DataIC50:  360nMAssay Description:Inhibition of ENPP1 (unknown origin)More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
LigandPNGBDBM50609352(CHEMBL5290907)
Affinity DataIC50:  389nMAssay Description:Inhibition of ENPP1 (unknown origin)More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
LigandPNGBDBM50609357(CHEMBL5285218)
Affinity DataIC50:  452nMAssay Description:Inhibition of ENPP1 (unknown origin)More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50011735(CHEMBL3262908)
Affinity DataIC50:  460nMAssay Description:Inhibition of recombinant N-terminal His6-tagged human reticulocyte 12/15-lipoxygenase using arachidonic acid as substrate by UV-vis spectrometric an...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50609351(CHEMBL5275034)
Affinity DataIC50:  525nMAssay Description:Inhibition of ENPP1 (unknown origin)More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50011783(CHEMBL3262925)
Affinity DataIC50:  550nMAssay Description:Inhibition of recombinant N-terminal His6-tagged human reticulocyte 12/15-lipoxygenase using arachidonic acid as substrate by UV-vis spectrometric an...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50609364(CHEMBL5286609)
Affinity DataIC50:  669nMAssay Description:Inhibition of ENPP1 (unknown origin)More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50011733(CHEMBL3262906)
Affinity DataIC50:  730nMAssay Description:Inhibition of recombinant N-terminal His6-tagged human reticulocyte 12/15-lipoxygenase using arachidonic acid as substrate by UV-vis spectrometric an...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50609363(CHEMBL5289139)
Affinity DataIC50:  759nMAssay Description:Inhibition of ENPP1 (unknown origin)More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
LigandPNGBDBM50609350(CHEMBL5278671)
Affinity DataIC50:  766nMAssay Description:Inhibition of ENPP1 (unknown origin)More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
LigandPNGBDBM50609361(CHEMBL5279855)
Affinity DataIC50:  773nMAssay Description:Inhibition of ENPP1 (unknown origin)More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50011736(CHEMBL3262909)
Affinity DataIC50:  810nMAssay Description:Inhibition of recombinant N-terminal His6-tagged human reticulocyte 12/15-lipoxygenase using arachidonic acid as substrate by UV-vis spectrometric an...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50208823(6,11-dihydrothiochromeno[4,3-b]indole | CHEMBL1809...)
Affinity DataIC50:  810nMAssay Description:Inhibition of human 12/15-LOX expressed in HEK293 cells after 30 mins by microplate reader analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50609358(CHEMBL5274733)
Affinity DataIC50:  916nMAssay Description:Inhibition of ENPP1 (unknown origin)More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
LigandPNGBDBM50609353(CHEMBL5265786)
Affinity DataIC50:  1.16E+3nMAssay Description:Inhibition of ENPP1 (unknown origin)More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50011769(CHEMBL1588672)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of recombinant N-terminal His6-tagged human reticulocyte 12/15-lipoxygenase using arachidonic acid as substrate by UV-vis spectrometric an...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM56150((6E)-4-methyl-6-[5-(2-methylphenyl)-1,2-dihydropyr...)
Affinity DataIC50:  3.40E+3nMAssay Description:Inhibition of N-terminal His6-tagged human 12/15-LOX using arachidonic acid as substrate by UV-visible spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50011732(CHEMBL3262905)
Affinity DataIC50:  3.60E+3nMAssay Description:Inhibition of recombinant N-terminal His6-tagged human reticulocyte 12/15-lipoxygenase using arachidonic acid as substrate by UV-vis spectrometric an...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50011742(CHEMBL3262915)
Affinity DataIC50:  3.90E+3nMAssay Description:Inhibition of recombinant N-terminal His6-tagged human reticulocyte 12/15-lipoxygenase using arachidonic acid as substrate by UV-vis spectrometric an...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM49247((6Z)-6-[5-(2-chlorophenyl)-1,2-dihydropyrazol-3-yl...)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of N-terminal His6-tagged human 12/15-LOX using arachidonic acid as substrate by UV-visible spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50011786(CHEMBL3262927)
Affinity DataIC50:  5.40E+3nMAssay Description:Inhibition of recombinant N-terminal His6-tagged human reticulocyte 12/15-lipoxygenase using arachidonic acid as substrate by UV-vis spectrometric an...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50148015(CHEMBL1540577)
Affinity DataIC50:  6.00E+3nMAssay Description:Inhibition of N-terminal His6-tagged human 12/15-LOX using arachidonic acid as substrate by UV-visible spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50011744(CHEMBL3262916)
Affinity DataIC50:  6.30E+3nMAssay Description:Inhibition of recombinant N-terminal His6-tagged human reticulocyte 12/15-lipoxygenase using arachidonic acid as substrate by UV-vis spectrometric an...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50187067(2-(5-(2-chlorophenyl)-1H-pyrazol-3-yl)-4-methoxyph...)
Affinity DataIC50:  6.60E+3nMAssay Description:Inhibition of N-terminal His6-tagged human 12/15-LOX using arachidonic acid as substrate by UV-visible spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM57040((6E)-6-[5-(3-bromophenyl)-1,2-dihydropyrazol-3-yli...)
Affinity DataIC50:  7.00E+3nMAssay Description:Inhibition of N-terminal His6-tagged human 12/15-LOX using arachidonic acid as substrate by UV-visible spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50148017(CHEMBL1353771)
Affinity DataIC50:  7.00E+3nMAssay Description:Inhibition of N-terminal His6-tagged human 12/15-LOX using arachidonic acid as substrate by UV-visible spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50148019(CHEMBL1604272)
Affinity DataIC50:  7.00E+3nMAssay Description:Inhibition of N-terminal His6-tagged human 12/15-LOX using arachidonic acid as substrate by UV-visible spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50609354(CHEMBL5270128)
Affinity DataIC50:  7.46E+3nMAssay Description:Inhibition of ENPP1 (unknown origin)More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50011738(CHEMBL3262911)
Affinity DataIC50:  7.60E+3nMAssay Description:Inhibition of recombinant N-terminal His6-tagged human reticulocyte 12/15-lipoxygenase using arachidonic acid as substrate by UV-vis spectrometric an...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50148023(CHEMBL1448722)
Affinity DataIC50:  9.10E+3nMAssay Description:Inhibition of N-terminal His6-tagged human 12/15-LOX using arachidonic acid as substrate by UV-visible spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM78048((6E)-6-[5-(3-fluorophenyl)-1,2-dihydropyrazol-3-yl...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of N-terminal His6-tagged human 12/15-LOX using arachidonic acid as substrate by UV-visible spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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