TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
National Cancer Institute-Bethesda
National Cancer Institute-Bethesda
Affinity DataKi: 0.00230nM ΔG°: -69.1kJ/molepH: 6.2 T: 2°CAssay Description:Inhibition constants were determined by a fluorometric assay with the fluorogenic substrate Arg-Glu(EDANS)-Ser-Gln-Asn-Tyr-Pro-Ile-Val-Lys(DABCYL)-Ar...More data for this Ligand-Target Pair
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
National Cancer Institute-Bethesda
National Cancer Institute-Bethesda
Affinity DataKi: 0.00550nM ΔG°: -66.9kJ/molepH: 6.2 T: 2°CAssay Description:Inhibition constants were determined by a fluorometric assay with the fluorogenic substrate Arg-Glu(EDANS)-Ser-Gln-Asn-Tyr-Pro-Ile-Val-Lys(DABCYL)-Ar...More data for this Ligand-Target Pair
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
National Cancer Institute-Bethesda
National Cancer Institute-Bethesda
Affinity DataKi: 0.00680nM ΔG°: -66.3kJ/molepH: 6.2 T: 2°CAssay Description:Inhibition constants were determined by a fluorometric assay with the fluorogenic substrate Arg-Glu(EDANS)-Ser-Gln-Asn-Tyr-Pro-Ile-Val-Lys(DABCYL)-Ar...More data for this Ligand-Target Pair
TargetIntegrin alpha-4/Integrin beta-7/Mucosal addressin cell adhesion molecule 1(Mus musculus (Mouse))
Ea Pharma
US Patent
Ea Pharma
US Patent
Affinity DataIC50: 0.0600nMpH: 9.6 T: 2°CAssay Description:The ability of test substances to inhibit the binding of a human B cell line, RPMI-8866, which is known to express α4β7 integrin, to MAdCA...More data for this Ligand-Target Pair
TargetIntegrin alpha-4/Integrin beta-7/Mucosal addressin cell adhesion molecule 1(Mus musculus (Mouse))
Ea Pharma
US Patent
Ea Pharma
US Patent
Affinity DataIC50: 0.0770nMpH: 9.6 T: 2°CAssay Description:The ability of test substances to inhibit the binding of a human B cell line, RPMI-8866, which is known to express α4β7 integrin, to MAdCA...More data for this Ligand-Target Pair
TargetIntegrin alpha-4/Integrin beta-7/Mucosal addressin cell adhesion molecule 1(Mus musculus (Mouse))
Ea Pharma
US Patent
Ea Pharma
US Patent
Affinity DataIC50: 0.0980nMpH: 9.6 T: 2°CAssay Description:The ability of test substances to inhibit the binding of a human B cell line, RPMI-8866, which is known to express α4β7 integrin, to MAdCA...More data for this Ligand-Target Pair
TargetIntegrin alpha-4/Integrin beta-7/Mucosal addressin cell adhesion molecule 1(Mus musculus (Mouse))
Ea Pharma
US Patent
Ea Pharma
US Patent
Affinity DataIC50: 0.130nMpH: 9.6 T: 2°CAssay Description:The ability of test substances to inhibit the binding of a human B cell line, RPMI-8866, which is known to express α4β7 integrin, to MAdCA...More data for this Ligand-Target Pair
TargetIntegrin alpha-4/Integrin beta-7/Mucosal addressin cell adhesion molecule 1(Mus musculus (Mouse))
Ea Pharma
US Patent
Ea Pharma
US Patent
Affinity DataIC50: 0.170nMpH: 9.6 T: 2°CAssay Description:The ability of test substances to inhibit the binding of a human B cell line, RPMI-8866, which is known to express α4β7 integrin, to MAdCA...More data for this Ligand-Target Pair
TargetIntegrin alpha-4/Integrin beta-7/Mucosal addressin cell adhesion molecule 1(Mus musculus (Mouse))
Ea Pharma
US Patent
Ea Pharma
US Patent
Affinity DataIC50: 0.210nMpH: 9.6 T: 2°CAssay Description:The ability of test substances to inhibit the binding of a human B cell line, RPMI-8866, which is known to express α4β7 integrin, to MAdCA...More data for this Ligand-Target Pair
TargetIntegrin alpha-4/Integrin beta-7/Mucosal addressin cell adhesion molecule 1(Mus musculus (Mouse))
Ea Pharma
US Patent
Ea Pharma
US Patent
Affinity DataIC50: 0.240nMpH: 9.6 T: 2°CAssay Description:The ability of test substances to inhibit the binding of a human B cell line, RPMI-8866, which is known to express α4β7 integrin, to MAdCA...More data for this Ligand-Target Pair
TargetIntegrin alpha-4/Integrin beta-7/Mucosal addressin cell adhesion molecule 1(Mus musculus (Mouse))
Ea Pharma
US Patent
Ea Pharma
US Patent
Affinity DataIC50: 0.260nMpH: 9.6 T: 2°CAssay Description:The ability of test substances to inhibit the binding of a human B cell line, RPMI-8866, which is known to express α4β7 integrin, to MAdCA...More data for this Ligand-Target Pair
TargetIntegrin alpha-4/Integrin beta-7/Mucosal addressin cell adhesion molecule 1(Mus musculus (Mouse))
Ea Pharma
US Patent
Ea Pharma
US Patent
Affinity DataIC50: 0.270nMpH: 9.6 T: 2°CAssay Description:The ability of test substances to inhibit the binding of a human B cell line, RPMI-8866, which is known to express α4β7 integrin, to MAdCA...More data for this Ligand-Target Pair
TargetIntegrin alpha-4/Integrin beta-7/Mucosal addressin cell adhesion molecule 1(Mus musculus (Mouse))
Ea Pharma
US Patent
Ea Pharma
US Patent
Affinity DataIC50: 0.270nMpH: 9.6 T: 2°CAssay Description:The ability of test substances to inhibit the binding of a human B cell line, RPMI-8866, which is known to express α4β7 integrin, to MAdCA...More data for this Ligand-Target Pair
TargetIntegrin alpha-4/Integrin beta-7/Mucosal addressin cell adhesion molecule 1(Mus musculus (Mouse))
Ea Pharma
US Patent
Ea Pharma
US Patent
Affinity DataIC50: 0.270nMpH: 9.6 T: 2°CAssay Description:The ability of test substances to inhibit the binding of a human B cell line, RPMI-8866, which is known to express α4β7 integrin, to MAdCA...More data for this Ligand-Target Pair
TargetIntegrin alpha-4/Integrin beta-7/Mucosal addressin cell adhesion molecule 1(Mus musculus (Mouse))
Ea Pharma
US Patent
Ea Pharma
US Patent
Affinity DataIC50: 0.320nMpH: 9.6 T: 2°CAssay Description:The ability of test substances to inhibit the binding of a human B cell line, RPMI-8866, which is known to express α4β7 integrin, to MAdCA...More data for this Ligand-Target Pair
TargetIntegrin alpha-4/Integrin beta-7/Mucosal addressin cell adhesion molecule 1(Mus musculus (Mouse))
Ea Pharma
US Patent
Ea Pharma
US Patent
Affinity DataIC50: 0.320nMpH: 9.6 T: 2°CAssay Description:The ability of test substances to inhibit the binding of a human B cell line, RPMI-8866, which is known to express α4β7 integrin, to MAdCA...More data for this Ligand-Target Pair
TargetIntegrin alpha-4/Integrin beta-7/Mucosal addressin cell adhesion molecule 1(Mus musculus (Mouse))
Ea Pharma
US Patent
Ea Pharma
US Patent
Affinity DataIC50: 0.380nMpH: 9.6 T: 2°CAssay Description:The ability of test substances to inhibit the binding of a human B cell line, RPMI-8866, which is known to express α4β7 integrin, to MAdCA...More data for this Ligand-Target Pair
TargetIntegrin alpha-4/Integrin beta-7/Mucosal addressin cell adhesion molecule 1(Mus musculus (Mouse))
Ea Pharma
US Patent
Ea Pharma
US Patent
Affinity DataIC50: 0.390nMpH: 9.6 T: 2°CAssay Description:The ability of test substances to inhibit the binding of a human B cell line, RPMI-8866, which is known to express α4β7 integrin, to MAdCA...More data for this Ligand-Target Pair
TargetIntegrin alpha-4/Integrin beta-7/Mucosal addressin cell adhesion molecule 1(Mus musculus (Mouse))
Ea Pharma
US Patent
Ea Pharma
US Patent
Affinity DataIC50: 0.410nMpH: 9.6 T: 2°CAssay Description:The ability of test substances to inhibit the binding of a human B cell line, RPMI-8866, which is known to express α4β7 integrin, to MAdCA...More data for this Ligand-Target Pair
TargetIntegrin alpha-4/Integrin beta-7/Mucosal addressin cell adhesion molecule 1(Mus musculus (Mouse))
Ea Pharma
US Patent
Ea Pharma
US Patent
Affinity DataIC50: 0.430nMpH: 9.6 T: 2°CAssay Description:The ability of test substances to inhibit the binding of a human B cell line, RPMI-8866, which is known to express α4β7 integrin, to MAdCA...More data for this Ligand-Target Pair
TargetIntegrin alpha-4/Integrin beta-7/Mucosal addressin cell adhesion molecule 1(Mus musculus (Mouse))
Ea Pharma
US Patent
Ea Pharma
US Patent
Affinity DataIC50: 0.460nMpH: 9.6 T: 2°CAssay Description:The ability of test substances to inhibit the binding of a human B cell line, RPMI-8866, which is known to express α4β7 integrin, to MAdCA...More data for this Ligand-Target Pair
TargetIntegrin alpha-4/Integrin beta-7/Mucosal addressin cell adhesion molecule 1(Mus musculus (Mouse))
Ea Pharma
US Patent
Ea Pharma
US Patent
Affinity DataIC50: 0.550nMpH: 9.6 T: 2°CAssay Description:The ability of test substances to inhibit the binding of a human B cell line, RPMI-8866, which is known to express α4β7 integrin, to MAdCA...More data for this Ligand-Target Pair
TargetIntegrin alpha-4/Integrin beta-7/Mucosal addressin cell adhesion molecule 1(Mus musculus (Mouse))
Ea Pharma
US Patent
Ea Pharma
US Patent
Affinity DataIC50: 0.560nMpH: 9.6 T: 2°CAssay Description:The ability of test substances to inhibit the binding of a human B cell line, RPMI-8866, which is known to express α4β7 integrin, to MAdCA...More data for this Ligand-Target Pair
TargetIntegrin alpha-4/Integrin beta-7/Mucosal addressin cell adhesion molecule 1(Mus musculus (Mouse))
Ea Pharma
US Patent
Ea Pharma
US Patent
Affinity DataIC50: 0.620nMpH: 9.6 T: 2°CAssay Description:The ability of test substances to inhibit the binding of a human B cell line, RPMI-8866, which is known to express α4β7 integrin, to MAdCA...More data for this Ligand-Target Pair
TargetIntegrin alpha-4/Integrin beta-7/Mucosal addressin cell adhesion molecule 1(Mus musculus (Mouse))
Ea Pharma
US Patent
Ea Pharma
US Patent
Affinity DataIC50: 0.640nMpH: 9.6 T: 2°CAssay Description:The ability of test substances to inhibit the binding of a human B cell line, RPMI-8866, which is known to express α4β7 integrin, to MAdCA...More data for this Ligand-Target Pair
TargetIntegrin alpha-4/Integrin beta-7/Mucosal addressin cell adhesion molecule 1(Mus musculus (Mouse))
Ea Pharma
US Patent
Ea Pharma
US Patent
Affinity DataIC50: 0.720nMpH: 9.6 T: 2°CAssay Description:The ability of test substances to inhibit the binding of a human B cell line, RPMI-8866, which is known to express α4β7 integrin, to MAdCA...More data for this Ligand-Target Pair
TargetIntegrin alpha-4/Integrin beta-7/Mucosal addressin cell adhesion molecule 1(Mus musculus (Mouse))
Ea Pharma
US Patent
Ea Pharma
US Patent
Affinity DataIC50: 0.730nMpH: 9.6 T: 2°CAssay Description:The ability of test substances to inhibit the binding of a human B cell line, RPMI-8866, which is known to express α4β7 integrin, to MAdCA...More data for this Ligand-Target Pair
TargetIntegrin alpha-4/Integrin beta-7/Mucosal addressin cell adhesion molecule 1(Mus musculus (Mouse))
Ea Pharma
US Patent
Ea Pharma
US Patent
Affinity DataIC50: 0.790nMpH: 9.6 T: 2°CAssay Description:The ability of test substances to inhibit the binding of a human B cell line, RPMI-8866, which is known to express α4β7 integrin, to MAdCA...More data for this Ligand-Target Pair
TargetIntegrin alpha-4/Integrin beta-7/Mucosal addressin cell adhesion molecule 1(Mus musculus (Mouse))
Ea Pharma
US Patent
Ea Pharma
US Patent
Affinity DataIC50: 0.800nMpH: 9.6 T: 2°CAssay Description:The ability of test substances to inhibit the binding of a human B cell line, RPMI-8866, which is known to express α4β7 integrin, to MAdCA...More data for this Ligand-Target Pair
TargetIntegrin alpha-4/Integrin beta-7/Mucosal addressin cell adhesion molecule 1(Mus musculus (Mouse))
Ea Pharma
US Patent
Ea Pharma
US Patent
Affinity DataIC50: 0.830nMpH: 9.6 T: 2°CAssay Description:The ability of test substances to inhibit the binding of a human B cell line, RPMI-8866, which is known to express α4β7 integrin, to MAdCA...More data for this Ligand-Target Pair
TargetIntegrin alpha-4/Integrin beta-7/Mucosal addressin cell adhesion molecule 1(Mus musculus (Mouse))
Ea Pharma
US Patent
Ea Pharma
US Patent
Affinity DataIC50: 0.900nMpH: 9.6 T: 2°CAssay Description:The ability of test substances to inhibit the binding of a human B cell line, RPMI-8866, which is known to express α4β7 integrin, to MAdCA...More data for this Ligand-Target Pair
TargetIntegrin alpha-4/Integrin beta-7/Mucosal addressin cell adhesion molecule 1(Mus musculus (Mouse))
Ea Pharma
US Patent
Ea Pharma
US Patent
Affinity DataIC50: 0.950nMpH: 9.6 T: 2°CAssay Description:The ability of test substances to inhibit the binding of a human B cell line, RPMI-8866, which is known to express α4β7 integrin, to MAdCA...More data for this Ligand-Target Pair
TargetIntegrin alpha-4/Integrin beta-7/Mucosal addressin cell adhesion molecule 1(Mus musculus (Mouse))
Ea Pharma
US Patent
Ea Pharma
US Patent
Affinity DataIC50: 0.970nMpH: 9.6 T: 2°CAssay Description:The ability of test substances to inhibit the binding of a human B cell line, RPMI-8866, which is known to express α4β7 integrin, to MAdCA...More data for this Ligand-Target Pair
TargetIntegrin alpha-4/Integrin beta-7/Mucosal addressin cell adhesion molecule 1(Mus musculus (Mouse))
Ea Pharma
US Patent
Ea Pharma
US Patent
Affinity DataIC50: 1nMpH: 9.6 T: 2°CAssay Description:The ability of test substances to inhibit the binding of a human B cell line, RPMI-8866, which is known to express α4β7 integrin, to MAdCA...More data for this Ligand-Target Pair
TargetIntegrin alpha-4/Integrin beta-7/Mucosal addressin cell adhesion molecule 1(Mus musculus (Mouse))
Ea Pharma
US Patent
Ea Pharma
US Patent
Affinity DataIC50: 1.10nMpH: 9.6 T: 2°CAssay Description:The ability of test substances to inhibit the binding of a human B cell line, RPMI-8866, which is known to express α4β7 integrin, to MAdCA...More data for this Ligand-Target Pair
TargetIntegrin alpha-4/Integrin beta-7/Mucosal addressin cell adhesion molecule 1(Mus musculus (Mouse))
Ea Pharma
US Patent
Ea Pharma
US Patent
Affinity DataIC50: 1.10nMpH: 9.6 T: 2°CAssay Description:The ability of test substances to inhibit the binding of a human B cell line, RPMI-8866, which is known to express α4β7 integrin, to MAdCA...More data for this Ligand-Target Pair
TargetIntegrin alpha-4/Integrin beta-7/Mucosal addressin cell adhesion molecule 1(Mus musculus (Mouse))
Ea Pharma
US Patent
Ea Pharma
US Patent
Affinity DataIC50: 1.30nMpH: 9.6 T: 2°CAssay Description:The ability of test substances to inhibit the binding of a human B cell line, RPMI-8866, which is known to express α4β7 integrin, to MAdCA...More data for this Ligand-Target Pair
TargetIntegrin alpha-4/Integrin beta-7/Mucosal addressin cell adhesion molecule 1(Mus musculus (Mouse))
Ea Pharma
US Patent
Ea Pharma
US Patent
Affinity DataIC50: 1.5nMpH: 9.6 T: 2°CAssay Description:The ability of test substances to inhibit the binding of a human B cell line, RPMI-8866, which is known to express α4β7 integrin, to MAdCA...More data for this Ligand-Target Pair
TargetIntegrin alpha-4/Integrin beta-7/Mucosal addressin cell adhesion molecule 1(Mus musculus (Mouse))
Ea Pharma
US Patent
Ea Pharma
US Patent
Affinity DataIC50: 1.60nMpH: 9.6 T: 2°CAssay Description:The ability of test substances to inhibit the binding of a human B cell line, RPMI-8866, which is known to express α4β7 integrin, to MAdCA...More data for this Ligand-Target Pair
TargetIntegrin alpha-4/Integrin beta-7/Mucosal addressin cell adhesion molecule 1(Mus musculus (Mouse))
Ea Pharma
US Patent
Ea Pharma
US Patent
Affinity DataIC50: 1.60nMpH: 9.6 T: 2°CAssay Description:The ability of test substances to inhibit the binding of a human B cell line, RPMI-8866, which is known to express α4β7 integrin, to MAdCA...More data for this Ligand-Target Pair
TargetIntegrin alpha-4/Integrin beta-7/Mucosal addressin cell adhesion molecule 1(Mus musculus (Mouse))
Ea Pharma
US Patent
Ea Pharma
US Patent
Affinity DataIC50: 1.60nMpH: 9.6 T: 2°CAssay Description:The ability of test substances to inhibit the binding of a human B cell line, RPMI-8866, which is known to express α4β7 integrin, to MAdCA...More data for this Ligand-Target Pair
TargetIntegrin alpha-4/Integrin beta-7/Mucosal addressin cell adhesion molecule 1(Mus musculus (Mouse))
Ea Pharma
US Patent
Ea Pharma
US Patent
Affinity DataIC50: 2nMpH: 9.6 T: 2°CAssay Description:The ability of test substances to inhibit the binding of a human B cell line, RPMI-8866, which is known to express α4β7 integrin, to MAdCA...More data for this Ligand-Target Pair
TargetIntegrin alpha-4/Integrin beta-7/Mucosal addressin cell adhesion molecule 1(Mus musculus (Mouse))
Ea Pharma
US Patent
Ea Pharma
US Patent
Affinity DataIC50: 2nMpH: 9.6 T: 2°CAssay Description:The ability of test substances to inhibit the binding of a human B cell line, RPMI-8866, which is known to express α4β7 integrin, to MAdCA...More data for this Ligand-Target Pair
TargetIntegrin alpha-4/Integrin beta-7/Mucosal addressin cell adhesion molecule 1(Mus musculus (Mouse))
Ea Pharma
US Patent
Ea Pharma
US Patent
Affinity DataIC50: 2.20nMpH: 9.6 T: 2°CAssay Description:The ability of test substances to inhibit the binding of a human B cell line, RPMI-8866, which is known to express α4β7 integrin, to MAdCA...More data for this Ligand-Target Pair
TargetIntegrin alpha-4/Integrin beta-7/Mucosal addressin cell adhesion molecule 1(Mus musculus (Mouse))
Ea Pharma
US Patent
Ea Pharma
US Patent
Affinity DataIC50: 2.60nMpH: 9.6 T: 2°CAssay Description:The ability of test substances to inhibit the binding of a human B cell line, RPMI-8866, which is known to express α4β7 integrin, to MAdCA...More data for this Ligand-Target Pair
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Yamanouchi Pharmaceutical
Yamanouchi Pharmaceutical
Affinity DataIC50: 2.60nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
TargetIntegrin alpha-4/Integrin beta-7/Mucosal addressin cell adhesion molecule 1(Mus musculus (Mouse))
Ea Pharma
US Patent
Ea Pharma
US Patent
Affinity DataIC50: 2.80nMpH: 9.6 T: 2°CAssay Description:The ability of test substances to inhibit the binding of a human B cell line, RPMI-8866, which is known to express α4β7 integrin, to MAdCA...More data for this Ligand-Target Pair
TargetGag-Pol polyprotein [588-1127,Y768C]/[588-1147,Y768C](Human immunodeficiency virus type 1)
Yamanouchi Pharmaceutical
Yamanouchi Pharmaceutical
Affinity DataIC50: 4nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
TargetGag-Pol polyprotein [588-1127,Y768C]/[588-1147,Y768C](Human immunodeficiency virus type 1)
Yamanouchi Pharmaceutical
Yamanouchi Pharmaceutical
Affinity DataIC50: 4nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
TargetIntegrin alpha-4/Integrin beta-7/Mucosal addressin cell adhesion molecule 1(Mus musculus (Mouse))
Ea Pharma
US Patent
Ea Pharma
US Patent
Affinity DataIC50: 4.10nMpH: 9.6 T: 2°CAssay Description:The ability of test substances to inhibit the binding of a human B cell line, RPMI-8866, which is known to express α4β7 integrin, to MAdCA...More data for this Ligand-Target Pair