Compile Data Set for Download or QSAR
maximum 50k data
Found 502 with Last Name = 'kaneko' and Initial = 'm'
TargetcAMP-dependent protein kinase(Oryctolagus cuniculus (Rabbit))
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM6760((+)-K-252a | CHEMBL281948 | K-252a | methyl (15S,1...)
Affinity DataIC50:  0.0160nMAssay Description:Inhibition of cAMP dependent Protein kinase A of rabbit Skeletal Muscle.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMyosin light chain kinase, smooth muscle(Gallus gallus (chicken))
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM6760((+)-K-252a | CHEMBL281948 | K-252a | methyl (15S,1...)
Affinity DataIC50:  0.0200nMAssay Description:Inhibition of Smooth muscle myosin light chain kinase of chicken gizzardMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-adrenergic receptor kinase 2(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50257340(CHEMBL4072828)
Affinity DataIC50:  0.650nMAssay Description:Inhibition of recombinant human full length GST-tagged GRK3 expressed in baculovirus using ulight topo2alpha as substrate preincubated for 60 mins fo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-adrenergic receptor kinase 1(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50173313(CHEMBL1738878)
Affinity DataIC50:  1.20nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged GRK2 expressed in baculovirus expression system using ulight topo2alpha as substrate preincubat...More data for this Ligand-Target Pair
TargetBeta-adrenergic receptor kinase 1(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50257447(CHEMBL4073882)
Affinity DataIC50:  1.70nMAssay Description:Inhibition of human GRK2 expressed in HEK-B2 cells assessed as isoproterenol-stimulated cAMP accumulation preincubation for 20 mins followed by isopr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-adrenergic receptor kinase 2(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50257328(CHEMBL4082775)
Affinity DataIC50:  1.80nMAssay Description:Inhibition of recombinant human full length GST-tagged GRK3 expressed in baculovirus using ulight topo2alpha as substrate preincubated for 60 mins fo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-adrenergic receptor kinase 1(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50257340(CHEMBL4072828)
Affinity DataIC50:  1.80nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged GRK2 expressed in baculovirus expression system using ulight topo2alpha as substrate preincubat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-adrenergic receptor kinase 1(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50257343(CHEMBL4086046)
Affinity DataIC50:  1.90nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged GRK2 expressed in baculovirus expression system using ulight topo2alpha as substrate preincubat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM6760((+)-K-252a | CHEMBL281948 | K-252a | methyl (15S,1...)
Affinity DataIC50:  2.40nMAssay Description:Ability to inhibit human trk A tyrosine kinase expressed in baculovirus using ELISA based enzyme assay was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-adrenergic receptor kinase 1(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50257445(CHEMBL4095659)
Affinity DataIC50:  3nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged GRK2 expressed in baculovirus expression system using ulight topo2alpha as substrate preincubat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C alpha/beta/delta/epsilon/eta/gamma/theta/zeta type(Rattus norvegicus)
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50108296(CHEMBL289772 | Indolocarbazole analogue)
Affinity DataIC50:  3nMAssay Description:Binding affinity towards 5-hydroxytryptamine 3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-adrenergic receptor kinase 2(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50257365(CHEMBL4083276)
Affinity DataIC50:  3.30nMAssay Description:Inhibition of recombinant human full length GST-tagged GRK3 expressed in baculovirus using ulight topo2alpha as substrate preincubated for 60 mins fo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-adrenergic receptor kinase 1(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50257426(CHEMBL4077447)
Affinity DataIC50:  3.90nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged GRK2 expressed in baculovirus expression system using ulight topo2alpha as substrate preincubat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-adrenergic receptor kinase 2(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50257344(CHEMBL4065690)
Affinity DataIC50:  4.30nMAssay Description:Inhibition of recombinant human full length GST-tagged GRK3 expressed in baculovirus using ulight topo2alpha as substrate preincubated for 60 mins fo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-adrenergic receptor kinase 2(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50257350(CHEMBL1738877)
Affinity DataIC50:  5.40nMAssay Description:Inhibition of recombinant human full length GST-tagged GRK3 expressed in baculovirus using ulight topo2alpha as substrate preincubated for 60 mins fo...More data for this Ligand-Target Pair
TargetBeta-adrenergic receptor kinase 1(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50257330(CHEMBL4071398)
Affinity DataIC50:  5.5nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged GRK2 expressed in baculovirus expression system using ulight topo2alpha as substrate preincubat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-adrenergic receptor kinase 1(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50257328(CHEMBL4082775)
Affinity DataIC50:  6.10nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged GRK2 expressed in baculovirus expression system using ulight topo2alpha as substrate preincubat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50376111(CHEMBL258618)
Affinity DataIC50:  6.40nMAssay Description:Inhibition of human JNK1 by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50376119(CHEMBL259484)
Affinity DataIC50:  6.80nMAssay Description:Inhibition of human JNK1 by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-adrenergic receptor kinase 1(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50257342(CHEMBL4103972)
Affinity DataIC50:  6.80nMAssay Description:Inhibition of human GRK2 expressed in HEK-B2 cells assessed as isoproterenol-stimulated cAMP accumulation preincubation for 20 mins followed by isopr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50376115(CHEMBL437107)
Affinity DataIC50:  7.30nMAssay Description:Inhibition of human JNK1 by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50257503(CHEMBL4067877)
Affinity DataIC50:  7.30nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged ROCK2 catalytic domain (1 to 553 residues) expressed in baculovirus expression system using STK...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-adrenergic receptor kinase 1(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50257365(CHEMBL4083276)
Affinity DataIC50:  7.5nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged GRK2 expressed in baculovirus expression system using ulight topo2alpha as substrate preincubat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50376123(CHEMBL260064)
Affinity DataIC50:  7.60nMAssay Description:Inhibition of human JNK1 by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-adrenergic receptor kinase 1(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50257341(CHEMBL4094447)
Affinity DataIC50:  7.80nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged GRK2 expressed in baculovirus expression system using ulight topo2alpha as substrate preincubat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50376122(CHEMBL260065)
Affinity DataIC50:  8.20nMAssay Description:Inhibition of human JNK1 by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50376118(CHEMBL258705)
Affinity DataIC50:  8.60nMAssay Description:Inhibition of human JNK1 by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50376114(CHEMBL259720)
Affinity DataIC50:  9.40nMAssay Description:Inhibition of human JNK1 by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50376120(CHEMBL259554)
Affinity DataIC50:  9.60nMAssay Description:Inhibition of human JNK1 by radiometric assayMore data for this Ligand-Target Pair
TargetBeta-adrenergic receptor kinase 1(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50257344(CHEMBL4065690)
Affinity DataIC50:  9.90nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged GRK2 expressed in baculovirus expression system using ulight topo2alpha as substrate preincubat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50376110(CHEMBL409350)
Affinity DataIC50:  10nMAssay Description:Inhibition of human JNK1 by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50376124(CHEMBL261413)
Affinity DataIC50:  10nMAssay Description:Inhibition of human JNK1 by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-dependent protein kinase(Oryctolagus cuniculus (Rabbit))
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50058332(CHEMBL299496 | methyl 10,23-di(ethylsulfanylmethyl...)
Affinity DataIC50: >10nMAssay Description:Inhibition of cAMP dependent Protein kinase A of rabbit Skeletal Muscle.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMyosin light chain kinase, smooth muscle(Gallus gallus (chicken))
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50058332(CHEMBL299496 | methyl 10,23-di(ethylsulfanylmethyl...)
Affinity DataIC50: >10nMAssay Description:Inhibition of Smooth muscle myosin light chain kinase of chicken gizzardMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50376125(CHEMBL411083)
Affinity DataIC50:  10nMAssay Description:Inhibition of human JNK1 by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase kinase kinase 11(Homo sapiens (Human))
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50108295(CHEMBL288817 | Indolocarbazole analogue)
Affinity DataIC50:  11nMAssay Description:Inhibition of Mixed lineage kinase 3 (MLK3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50376112(CHEMBL258845)
Affinity DataIC50:  11nMAssay Description:Inhibition of human JNK1 by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase kinase kinase 11(Homo sapiens (Human))
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50108296(CHEMBL289772 | Indolocarbazole analogue)
Affinity DataIC50:  11nMAssay Description:Inhibition of Mixed lineage kinase 3 (MLK3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase kinase kinase 11(Homo sapiens (Human))
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50108293(CHEMBL277817 | Indolocarbazole analogue)
Affinity DataIC50:  11nMAssay Description:Inhibition of Mixed lineage kinase 3 (MLK3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50376113(CHEMBL258631)
Affinity DataIC50:  11nMAssay Description:Inhibition of human JNK1 by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-adrenergic receptor kinase 1(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50257389(CHEMBL4093075)
Affinity DataIC50:  12nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged GRK2 expressed in baculovirus expression system using ulight topo2alpha as substrate preincubat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-adrenergic receptor kinase 1(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50257425(CHEMBL4060973)
Affinity DataIC50:  12nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged GRK2 expressed in baculovirus expression system using ulight topo2alpha as substrate preincubat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-adrenergic receptor kinase 1(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50257429(CHEMBL4061438)
Affinity DataIC50:  12nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged GRK2 expressed in baculovirus expression system using ulight topo2alpha as substrate preincubat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPhospho-N-acetylmuramoyl-pentapeptide-transferase(Escherichia coli (strain K12))
Sankyo

Curated by ChEMBL
LigandPNGBDBM50221211(CHEMBL97077)
Affinity DataIC50:  12.2nMAssay Description:Inhibitory activity against translocase IMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospho-N-acetylmuramoyl-pentapeptide-transferase(Escherichia coli (strain K12))
Sankyo

Curated by ChEMBL
LigandPNGBDBM50221211(CHEMBL97077)
Affinity DataIC50:  12.2nMAssay Description:Inhibitory concentration required against Translocase IMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospho-N-acetylmuramoyl-pentapeptide-transferase(Escherichia coli (strain K12))
Sankyo

Curated by ChEMBL
LigandPNGBDBM50221473(CHEMBL94424)
Affinity DataIC50:  13.9nMAssay Description:Inhibitory activity against translocase IMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-adrenergic receptor kinase 1(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50257366(CHEMBL4082559)
Affinity DataIC50:  14nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged GRK2 expressed in baculovirus expression system using ulight topo2alpha as substrate preincubat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-adrenergic receptor kinase 1(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50257409(CHEMBL4087117)
Affinity DataIC50:  14nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged GRK2 expressed in baculovirus expression system using ulight topo2alpha as substrate preincubat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase kinase kinase 9(Homo sapiens (Human))
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50108296(CHEMBL289772 | Indolocarbazole analogue)
Affinity DataIC50:  15nMAssay Description:Inhibition of Mixed lineage kinase 1 (MLK1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospho-N-acetylmuramoyl-pentapeptide-transferase(Escherichia coli (strain K12))
Sankyo

Curated by ChEMBL
LigandPNGBDBM50221201(CHEMBL97712)
Affinity DataIC50:  15.8nMAssay Description:Inhibitory activity against translocase IMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Displayed 1 to 50 (of 502 total ) | Next | Last >>
Jump to: