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Found 85 with Last Name = 'karumudi' and Initial = 'b'
TargetEstrogen receptor(Homo sapiens (Human))
University Of Illinois College Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50090462(CHEMBL3581693 | US20240043442, Example GDC-0810)
Affinity DataKi:  0.370nMAssay Description:Displacement of [3H]estradiol from full length recombinant human ESR1 expressed in insect cells by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
University Of Illinois College Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50233215(CHEMBL4070169)
Affinity DataKi:  0.5nMAssay Description:Displacement of [3H]estradiol from full length recombinant human ESR1 expressed in insect cells by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
University Of Illinois College Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50233216(CHEMBL4081807)
Affinity DataKi:  0.570nMAssay Description:Displacement of [3H]estradiol from full length recombinant human ESR1 expressed in insect cells by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
University Of Illinois College Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50233203(CHEMBL4098867)
Affinity DataKi:  0.650nMAssay Description:Displacement of [3H]estradiol from full length recombinant human ESR1 expressed in insect cells by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
University Of Illinois College Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50233205(CHEMBL4059888)
Affinity DataKi:  0.730nMAssay Description:Displacement of [3H]estradiol from full length recombinant human ESR1 expressed in insect cells by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
University Of Illinois College Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50233202(CHEMBL4092208)
Affinity DataKi:  1.30nMAssay Description:Displacement of [3H]estradiol from full length recombinant human ESR1 expressed in insect cells by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
University Of Illinois College Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50233204(CHEMBL4094499)
Affinity DataKi:  2nMAssay Description:Displacement of [3H]estradiol from full length recombinant human ESR1 expressed in insect cells by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
University Of Illinois College Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50233216(CHEMBL4081807)
Affinity DataIC50:  2.40nMAssay Description:Antagonist activity at ERalpha in tamoxifen-sensitive human MCF7:WS8 cells assessed as inhibition of estradiol-induced response after 18 hrs by lucif...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
University Of Illinois College Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50233205(CHEMBL4059888)
Affinity DataIC50:  3.10nMAssay Description:Antagonist activity at ERalpha in tamoxifen-sensitive human MCF7:WS8 cells assessed as inhibition of estradiol-induced response after 18 hrs by lucif...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
University Of Illinois College Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50233204(CHEMBL4094499)
Affinity DataIC50:  4.20nMAssay Description:Antagonist activity at ERalpha in tamoxifen-sensitive human MCF7:WS8 cells assessed as inhibition of estradiol-induced response after 18 hrs by lucif...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
University Of Illinois College Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50233215(CHEMBL4070169)
Affinity DataIC50:  4.5nMAssay Description:Antagonist activity at ERalpha in tamoxifen-sensitive human MCF7:WS8 cells assessed as inhibition of estradiol-induced response after 18 hrs by lucif...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
University Of Illinois College Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50233203(CHEMBL4098867)
Affinity DataIC50:  8.80nMAssay Description:Antagonist activity at ERalpha in tamoxifen-sensitive human MCF7:WS8 cells assessed as inhibition of estradiol-induced response after 18 hrs by lucif...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
University Of Illinois College Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50090462(CHEMBL3581693 | US20240043442, Example GDC-0810)
Affinity DataIC50:  11nMAssay Description:Antagonist activity at ERalpha in tamoxifen-sensitive human MCF7:WS8 cells assessed as inhibition of estradiol-induced response after 18 hrs by lucif...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
University Of Illinois College Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50233202(CHEMBL4092208)
Affinity DataIC50:  17nMAssay Description:Antagonist activity at ERalpha in tamoxifen-sensitive human MCF7:WS8 cells assessed as inhibition of estradiol-induced response after 18 hrs by lucif...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)
Affinity DataIC50:  29nMAssay Description:Inhibition of human recombinant HDAC1 using Boc-L-Lys (Ac)-AMC as substrate preincubated with compound for 5 mins measured after 35 mins by spectrofl...More data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)
Affinity DataIC50:  34nMAssay Description:Inhibition of human recombinant HDAC1 using Boc-L-Lys (Ac)-AMC as substrate preincubated with compound for 3 hrs measured after 35 mins by spectroflu...More data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50232053(CHEMBL271741 | N-(4-amino-biphenyl-3-yl)-benzamide...)
Affinity DataIC50:  52nMAssay Description:Inhibition of human recombinant HDAC1 using Boc-L-Lys (Ac)-AMC as substrate preincubated with compound for 3 hrs measured after 35 mins by spectroflu...More data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50387965(CHEMBL2057824)
Affinity DataIC50:  70nMAssay Description:Inhibition of human recombinant HDAC1 using Boc-L-Lys (Ac)-AMC as substrate preincubated with compound for 3 hrs measured after 35 mins by spectroflu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50387965(CHEMBL2057824)
Affinity DataIC50:  110nMAssay Description:Inhibition of human recombinant HDAC2 using Boc-L-Lys (Ac)-AMC as substrate preincubated with compound for 24 hrs measured after 35 mins by spectrofl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50232053(CHEMBL271741 | N-(4-amino-biphenyl-3-yl)-benzamide...)
Affinity DataIC50:  140nMAssay Description:Inhibition of human recombinant HDAC2 using Boc-L-Lys (Ac)-AMC as substrate preincubated with compound for 24 hrs measured after 35 mins by spectrofl...More data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50387967(CHEMBL2057823)
Affinity DataIC50:  140nMAssay Description:Inhibition of human recombinant HDAC1 using Boc-L-Lys (Ac)-AMC as substrate preincubated with compound for 3 hrs measured after 35 mins by spectroflu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)
Affinity DataIC50:  200nMAssay Description:Inhibition of human recombinant HDAC2 using Boc-L-Lys (Ac)-AMC as substrate preincubated with compound for 5 mins measured after 35 mins by spectrofl...More data for this Ligand-Target Pair
TargetHistone deacetylase 2(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50387967(CHEMBL2057823)
Affinity DataIC50:  210nMAssay Description:Inhibition of human recombinant HDAC2 using Boc-L-Lys (Ac)-AMC as substrate preincubated with compound for 24 hrs measured after 35 mins by spectrofl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)
Affinity DataIC50:  260nMAssay Description:Inhibition of human recombinant HDAC2 using Boc-L-Lys (Ac)-AMC as substrate preincubated with compound for 24 hrs measured after 35 mins by spectrofl...More data for this Ligand-Target Pair
TargetHistone deacetylase 2(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50387973(CHEMBL2057822)
Affinity DataIC50:  300nMAssay Description:Inhibition of human recombinant HDAC2 using Boc-L-Lys (Ac)-AMC as substrate preincubated with compound for 24 hrs measured after 35 mins by spectrofl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50387966(CHEMBL2057820)
Affinity DataIC50:  320nMAssay Description:Inhibition of human recombinant HDAC2 using Boc-L-Lys (Ac)-AMC as substrate preincubated with compound for 24 hrs measured after 35 mins by spectrofl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50232053(CHEMBL271741 | N-(4-amino-biphenyl-3-yl)-benzamide...)
Affinity DataIC50:  350nMAssay Description:Inhibition of human recombinant HDAC2 using Boc-L-Lys (Ac)-AMC as substrate preincubated with compound for 3 hrs measured after 35 mins by spectroflu...More data for this Ligand-Target Pair
TargetHistone deacetylase 2(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50387964(CHEMBL2057821)
Affinity DataIC50:  350nMAssay Description:Inhibition of human recombinant HDAC2 using Boc-L-Lys (Ac)-AMC as substrate preincubated with compound for 24 hrs measured after 35 mins by spectrofl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50232053(CHEMBL271741 | N-(4-amino-biphenyl-3-yl)-benzamide...)
Affinity DataIC50:  410nMAssay Description:Inhibition of human recombinant HDAC1 using Boc-L-Lys (Ac)-AMC as substrate preincubated with compound for 5 mins measured after 35 mins by spectrofl...More data for this Ligand-Target Pair
TargetHistone deacetylase 2(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50387965(CHEMBL2057824)
Affinity DataIC50:  690nMAssay Description:Inhibition of human recombinant HDAC2 using Boc-L-Lys (Ac)-AMC as substrate preincubated with compound for 3 hrs measured after 35 mins by spectroflu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50229191(CHEMBL252409 | US9096559, 15 | [4-(4-amino-bipheny...)
Affinity DataIC50:  740nMAssay Description:Inhibition of human recombinant HDAC2 using Boc-L-Lys (Ac)-AMC as substrate preincubated with compound for 24 hrs measured after 35 mins by spectrofl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50387971(CHEMBL2057828)
Affinity DataIC50:  750nMAssay Description:Inhibition of human recombinant HDAC2 using Boc-L-Lys (Ac)-AMC as substrate preincubated with compound for 24 hrs measured after 35 mins by spectrofl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50387966(CHEMBL2057820)
Affinity DataIC50:  780nMAssay Description:Inhibition of human recombinant HDAC1 using Boc-L-Lys (Ac)-AMC as substrate preincubated with compound for 3 hrs measured after 35 mins by spectroflu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50387970(CHEMBL2057827)
Affinity DataIC50:  830nMAssay Description:Inhibition of human recombinant HDAC2 using Boc-L-Lys (Ac)-AMC as substrate preincubated with compound for 24 hrs measured after 35 mins by spectrofl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50387964(CHEMBL2057821)
Affinity DataIC50:  990nMAssay Description:Inhibition of human recombinant HDAC1 using Boc-L-Lys (Ac)-AMC as substrate preincubated with compound for 3 hrs measured after 35 mins by spectroflu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50387973(CHEMBL2057822)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of human recombinant HDAC2 using Boc-L-Lys (Ac)-AMC as substrate preincubated with compound for 3 hrs measured after 35 mins by spectroflu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50387966(CHEMBL2057820)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of human recombinant HDAC2 using Boc-L-Lys (Ac)-AMC as substrate preincubated with compound for 3 hrs measured after 35 mins by spectroflu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50387967(CHEMBL2057823)
Affinity DataIC50:  1.05E+3nMAssay Description:Inhibition of human recombinant HDAC2 using Boc-L-Lys (Ac)-AMC as substrate preincubated with compound for 3 hrs measured after 35 mins by spectroflu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50387964(CHEMBL2057821)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of human recombinant HDAC2 using Boc-L-Lys (Ac)-AMC as substrate preincubated with compound for 3 hrs measured after 35 mins by spectroflu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50387965(CHEMBL2057824)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of human recombinant HDAC1 using Boc-L-Lys (Ac)-AMC as substrate preincubated with compound for 5 mins measured after 35 mins by spectrofl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50232053(CHEMBL271741 | N-(4-amino-biphenyl-3-yl)-benzamide...)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of human recombinant HDAC2 using Boc-L-Lys (Ac)-AMC as substrate preincubated with compound for 5 mins measured after 35 mins by spectrofl...More data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50387973(CHEMBL2057822)
Affinity DataIC50:  1.21E+3nMAssay Description:Inhibition of human recombinant HDAC1 using Boc-L-Lys (Ac)-AMC as substrate preincubated with compound for 3 hrs measured after 35 mins by spectroflu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50387968(CHEMBL2057825)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of human recombinant HDAC1 using Boc-L-Lys (Ac)-AMC as substrate preincubated with compound for 3 hrs measured after 35 mins by spectroflu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50229191(CHEMBL252409 | US9096559, 15 | [4-(4-amino-bipheny...)
Affinity DataIC50:  1.88E+3nMAssay Description:Inhibition of human recombinant HDAC1 using Boc-L-Lys (Ac)-AMC as substrate preincubated with compound for 3 hrs measured after 35 mins by spectroflu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50387967(CHEMBL2057823)
Affinity DataIC50:  2.10E+3nMAssay Description:Inhibition of human recombinant HDAC1 using Boc-L-Lys (Ac)-AMC as substrate preincubated with compound for 5 mins measured after 35 mins by spectrofl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50387968(CHEMBL2057825)
Affinity DataIC50:  2.40E+3nMAssay Description:Inhibition of human recombinant HDAC2 using Boc-L-Lys (Ac)-AMC as substrate preincubated with compound for 24 hrs measured after 35 mins by spectrofl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50387964(CHEMBL2057821)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibition of human recombinant HDAC1 using Boc-L-Lys (Ac)-AMC as substrate preincubated with compound for 5 mins measured after 35 mins by spectrofl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50387970(CHEMBL2057827)
Affinity DataIC50:  2.70E+3nMAssay Description:Inhibition of human recombinant HDAC1 using Boc-L-Lys (Ac)-AMC as substrate preincubated with compound for 3 hrs measured after 35 mins by spectroflu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50387973(CHEMBL2057822)
Affinity DataIC50:  2.80E+3nMAssay Description:Inhibition of human recombinant HDAC1 using Boc-L-Lys (Ac)-AMC as substrate preincubated with compound for 5 mins measured after 35 mins by spectrofl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50387965(CHEMBL2057824)
Affinity DataIC50:  3.20E+3nMAssay Description:Inhibition of human recombinant HDAC2 using Boc-L-Lys (Ac)-AMC as substrate preincubated with compound for 5 mins measured after 35 mins by spectrofl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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