Compile Data Set for Download or QSAR
maximum 50k data
Found 215 with Last Name = 'katayama' and Initial = 'n'
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Yamanouchi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50095997(3',4',7-trihydroxyisoflavone | CHEMBL13486)
Affinity DataKi:  38nMAssay Description:Inhibitory activity against tautomerase macrophage migration inhibitory factor (MIF)More data for this Ligand-Target Pair
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Yamanouchi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50096004(7-Hydroxy-3-[4-(2-oxo-2H-chromen-3-yl)-thiazol-2-y...)
Affinity DataKi:  280nMAssay Description:Inhibitory activity against tautomerase macrophage migration inhibitory factor (MIF)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Yamanouchi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50096003(7-Hydroxy-3-phenyl-chromen-2-one | 7-hydroxy-3-phe...)
Affinity DataKi:  470nMAssay Description:Inhibitory activity against tautomerase macrophage migration inhibitory factor (MIF)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Yamanouchi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50096001(7-Hydroxy-3-pyrazolo[1,5-a]pyridin-2-yl-chromen-2-...)
Affinity DataKi:  500nMAssay Description:Inhibitory activity against tautomerase macrophage migration inhibitory factor (MIF)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Yamanouchi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50095993(7-Hydroxy-2-oxo-2H-chromene-3-carbothioic acid ami...)
Affinity DataKi:  550nMAssay Description:Inhibitory activity against tautomerase macrophage migration inhibitory factor (MIF)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Yamanouchi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50096002(3-(4-Benzo[1,3]dioxol-5-yl-thiazol-2-yl)-7-hydroxy...)
Affinity DataKi:  1.50E+3nMAssay Description:Inhibitory activity against tautomerase macrophage migration inhibitory factor (MIF)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Yamanouchi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50096007(2-Oxo-2H-chromene-3-carboxylic acid 2-oxo-2-phenyl...)
Affinity DataKi:  1.60E+3nMAssay Description:Inhibitory activity against tautomerase macrophage migration inhibitory factor (MIF)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Yamanouchi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50096006(7-Hydroxy-3-(2-methyl-thiazol-4-yl)-chromen-2-one ...)
Affinity DataKi:  2.10E+3nMAssay Description:Inhibitory activity against tautomerase macrophage migration inhibitory factor (MIF)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Yamanouchi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50096000(3-(2-Fluoro-4-hydroxy-phenyl)-acrylic acid anion)
Affinity DataKi:  2.60E+3nMAssay Description:Inhibitory activity against tautomerase macrophage migration inhibitory factor (MIF)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Yamanouchi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50095994(3-Cyano-7-hydroxycoumarin (2) | 7-Hydroxy-2-oxo-2H...)
Affinity DataKi:  2.90E+3nMAssay Description:Inhibitory activity against tautomerase macrophage migration inhibitory factor (MIF)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Yamanouchi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50096005(7-Hydroxy-3-(4-methyl-thiazol-2-yl)-chromen-2-one ...)
Affinity DataKi:  3.10E+3nMAssay Description:Inhibitory activity against tautomerase macrophage migration inhibitory factor (MIF)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Yamanouchi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50096008(3-Acetyl-7-hydroxy-chromen-2-one | 3-acetyl-7-hydr...)
Affinity DataKi:  4.30E+3nMAssay Description:Inhibitory activity against tautomerase macrophage migration inhibitory factor (MIF)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Yamanouchi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50095996(3-(7-Hydroxy-2-oxo-2H-chromen-3-yl)-3-oxo-propioni...)
Affinity DataKi:  5.80E+3nMAssay Description:Inhibitory activity against tautomerase macrophage migration inhibitory factor (MIF)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Yamanouchi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50096009(3-(4-Dimethylamino-benzylidene)-chroman-2,4-dione ...)
Affinity DataKi:  6.20E+3nMAssay Description:Inhibitory activity against tautomerase macrophage migration inhibitory factor (MIF)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Yamanouchi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50095995(7-HYDROXY-2-OXO-CHROMENE-3-CARBOXYLIC ACID ETHYL E...)
Affinity DataKi:  7.40E+3nMAssay Description:Inhibitory activity against tautomerase macrophage migration inhibitory factor (MIF)More data for this Ligand-Target Pair
TargetGlycogen phosphorylase, liver form(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50246785((2E,2'E)-N,N'-(Thiodiethane-2,1-diyl)bis[3-(3,4-di...)
Affinity DataIC50:  12nMAssay Description:Inhibition of human liver glycogen phosphorylase a in presence of glucoseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50361337(CHEMBL1933845)
Affinity DataIC50:  12nMAssay Description:Displacement of [3H]-AD-5061 from human GST-tagged PPARgammaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50361338(CHEMBL1933842)
Affinity DataIC50:  15nMAssay Description:Displacement of [3H]-AD-5061 from human GST-tagged PPARgammaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen phosphorylase, liver form(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM35353(indole-2-carboxamide derivative, 25e (R-isomer))
Affinity DataIC50:  20nMpH: 6.8 T: 2°CAssay Description:The activity of recombinant human liver GPa in the forward direction was measured by monitoring the production of NADPH. Enzyme activity was assayed...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50361340(CHEMBL1933822)
Affinity DataIC50:  21nMAssay Description:Displacement of [3H]-AD-5061 from human GST-tagged PPARgammaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50361339(CHEMBL1933841)
Affinity DataIC50:  23nMAssay Description:Displacement of [3H]-AD-5061 from human GST-tagged PPARgammaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen phosphorylase, liver form(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50246632((2E,2'E)-N,N'-Pentane-1,5-diylbis[3-(3,4-dichlorop...)
Affinity DataIC50:  23nMAssay Description:Inhibition of human liver glycogen phosphorylase a in presence of glucoseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen phosphorylase, liver form(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50246752((2E,2'E)-N,N'-(Oxydiethane-2,1-diyl)bis[3-(3,4-dic...)
Affinity DataIC50:  26nMAssay Description:Inhibition of human liver glycogen phosphorylase a in presence of glucoseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen phosphorylase, liver form(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50246786((2E,2'E)-N,N'-(Sulfinyldiethane-2,1-diyl)bis[3-(3,...)
Affinity DataIC50:  26nMAssay Description:Inhibition of human liver glycogen phosphorylase a in presence of glucoseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen phosphorylase, liver form(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM35351(indole-2-carboxamide derivative, 25e)
Affinity DataIC50:  36nMpH: 6.8 T: 2°CAssay Description:The activity of recombinant human liver GPa in the forward direction was measured by monitoring the production of NADPH. Enzyme activity was assayed...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen phosphorylase, liver form(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50246788((2E,2'E)-N,N'-Butane-1,4-diylbis[3-(3,4-dichloroph...)
Affinity DataIC50:  43nMAssay Description:Inhibition of human liver glycogen phosphorylase a in presence of glucoseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50106720(CHEMBL3600880)
Affinity DataIC50:  44nMAssay Description:Inhibition of CYP2D6 (unknown origin) by fluorescence-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen phosphorylase, liver form(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM35350(indole-2-carboxamide derivative, 25d)
Affinity DataIC50:  48nMpH: 6.8 T: 2°CAssay Description:The activity of recombinant human liver GPa in the forward direction was measured by monitoring the production of NADPH. Enzyme activity was assayed...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen phosphorylase, liver form(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM35349(indole-2-carboxamide derivative, 25c)
Affinity DataIC50:  63nMpH: 6.8 T: 2°CAssay Description:The activity of recombinant human liver GPa in the forward direction was measured by monitoring the production of NADPH. Enzyme activity was assayed...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen phosphorylase, liver form(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM35345(indole-2-carboxamide derivative, 15)
Affinity DataIC50:  68nMpH: 6.8 T: 2°CAssay Description:The activity of recombinant human liver GPa in the forward direction was measured by monitoring the production of NADPH. Enzyme activity was assayed...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50106719(CHEMBL3600879)
Affinity DataIC50:  68nMAssay Description:Inhibition of CYP2D6 (unknown origin) by fluorescence-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen phosphorylase, liver form(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM35352(indole-2-carboxamide derivative, 25e (S-isomer))
Affinity DataIC50:  160nMpH: 6.8 T: 2°CAssay Description:The activity of recombinant human liver GPa in the forward direction was measured by monitoring the production of NADPH. Enzyme activity was assayed...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen phosphorylase, liver form(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM35636(5-chloroindolecarboxamide, 13a)
Affinity DataIC50:  250nMpH: 6.8 T: 2°CAssay Description:The activity of recombinant human liver GPa in the forward direction was measured by monitoring the production of NADPH. Enzyme activity was assayed...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlycogen phosphorylase, liver form(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50246632((2E,2'E)-N,N'-Pentane-1,5-diylbis[3-(3,4-dichlorop...)
Affinity DataIC50:  260nMAssay Description:Inhibition of human liver glycogen phosphorylase a in absence of glucoseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50106714(CHEMBL3600876)
Affinity DataIC50: <300nMAssay Description:Inhibition of CYP2D6 (unknown origin) by fluorescence-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen phosphorylase, liver form(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50246786((2E,2'E)-N,N'-(Sulfinyldiethane-2,1-diyl)bis[3-(3,...)
Affinity DataIC50:  310nMAssay Description:Inhibition of human liver glycogen phosphorylase a in absence of glucoseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen phosphorylase, liver form(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM35339(indole-2-carboxamide derivative, 5b)
Affinity DataIC50:  320nMpH: 6.8 T: 2°CAssay Description:The activity of recombinant human liver GPa in the forward direction was measured by monitoring the production of NADPH. Enzyme activity was assayed...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50382055(CHEMBL2024606)
Affinity DataIC50:  330nMAssay Description:Displacement of [3H]-AD-5061 from human GST-tagged PPARgammaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen phosphorylase, liver form(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM35633(5-chloroindolecarboxamide, 9h)
Affinity DataIC50:  340nMpH: 6.8 T: 2°CAssay Description:The activity of recombinant human liver GPa in the forward direction was measured by monitoring the production of NADPH. Enzyme activity was assayed...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50095969(CHEMBL3593436)
Affinity DataIC50: <390nMAssay Description:Inhibition of CYP2D6 (unknown origin) by fluorescence-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50106722(CHEMBL3600882)
Affinity DataIC50: <390nMAssay Description:Inhibition of CYP2D6 (unknown origin) by fluorescence-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen phosphorylase, liver form(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50246788((2E,2'E)-N,N'-Butane-1,4-diylbis[3-(3,4-dichloroph...)
Affinity DataIC50:  420nMAssay Description:Inhibition of human liver glycogen phosphorylase a in absence of glucoseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen phosphorylase, liver form(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM35628(5-chloroindolecarboxamide, 9c)
Affinity DataIC50:  420nMpH: 6.8 T: 2°CAssay Description:The activity of recombinant human liver GPa in the forward direction was measured by monitoring the production of NADPH. Enzyme activity was assayed...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen phosphorylase, liver form(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50246752((2E,2'E)-N,N'-(Oxydiethane-2,1-diyl)bis[3-(3,4-dic...)
Affinity DataIC50:  430nMAssay Description:Inhibition of human liver glycogen phosphorylase a in absence of glucoseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen phosphorylase, liver form(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM35638(5-chloroindolecarboxamide, 13c)
Affinity DataIC50:  440nMpH: 6.8 T: 2°CAssay Description:The activity of recombinant human liver GPa in the forward direction was measured by monitoring the production of NADPH. Enzyme activity was assayed...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlycogen phosphorylase, liver form(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM35338(indole-2-carboxamide derivative, 3)
Affinity DataIC50:  440nMpH: 6.8 T: 2°CAssay Description:The activity of recombinant human liver GPa in the forward direction was measured by monitoring the production of NADPH. Enzyme activity was assayed...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen phosphorylase, liver form(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50246785((2E,2'E)-N,N'-(Thiodiethane-2,1-diyl)bis[3-(3,4-di...)
Affinity DataIC50:  450nMAssay Description:Inhibition of human liver glycogen phosphorylase a in absence of glucoseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen phosphorylase, liver form(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM35348(indole-2-carboxamide derivative, 25b)
Affinity DataIC50:  590nMpH: 6.8 T: 2°CAssay Description:The activity of recombinant human liver GPa in the forward direction was measured by monitoring the production of NADPH. Enzyme activity was assayed...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50037212(CHEMBL3356251)
Affinity DataIC50:  600nMAssay Description:Inhibition of CYP2D6 (unknown origin) by fluorescence-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50037209(CHEMBL3356247)
Affinity DataIC50:  780nMAssay Description:Inhibition of CYP2D6 (unknown origin) by fluorescence-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Displayed 1 to 50 (of 215 total ) | Next | Last >>
Jump to: