Compile Data Set for Download or QSAR
maximum 50k data
Found 138 with Last Name = 'khedkar' and Initial = 'vm'
TargetEnoyl-acyl carrier reductase(Plasmodium falciparum)
Bombay College Of Pharmacy

LigandPNGBDBM8726(5-chloro-2-(2,4-dichlorophenoxy)phenol | CHEMBL849...)
Affinity DataIC50:  49nMpH: 7.4Assay Description:Inhibition assay using pfENR.More data for this Ligand-Target Pair
TargetRetinoblastoma-associated protein(Homo sapiens (Human))
Padmashri Vikhe Patil College Of Arts

Curated by ChEMBL
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)
Affinity DataIC50:  66nMAssay Description:Inhibition of retinoblastoma protein phosphorylation in human MDA-MB-231 cells after 16 hrs by Hoechst 33342 staining based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTumor necrosis factor(Homo sapiens (Human))
Padmashri Vikhe Patil College Of Arts

Curated by ChEMBL
LigandPNGBDBM14361((R,S)-Rolipram | 4-(3-cyclopentyloxy-4-methoxy-phe...)
Affinity DataIC50:  200nMAssay Description:Inhibition of LPS-induced TNF-alpha production in human MNC suspension after 20 hrs by radioimmunoassayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTumor necrosis factor(Homo sapiens (Human))
Padmashri Vikhe Patil College Of Arts

Curated by ChEMBL
LigandPNGBDBM50454030(CHEMBL4214663)
Affinity DataIC50:  300nMAssay Description:Inhibition of LPS-induced TNF-alpha production in human PBMC preincubated for 30 mins followed by LPS addition measured after 5 hrs by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTumor necrosis factor(Homo sapiens (Human))
Padmashri Vikhe Patil College Of Arts

Curated by ChEMBL
LigandPNGBDBM50453983(CHEMBL4215614)
Affinity DataIC50:  500nMAssay Description:Inhibition of LPS-induced TNF-alpha production in human PBMC preincubated for 30 mins followed by LPS addition measured after 5 hrs by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTumor necrosis factor(Homo sapiens (Human))
Padmashri Vikhe Patil College Of Arts

Curated by ChEMBL
LigandPNGBDBM14361((R,S)-Rolipram | 4-(3-cyclopentyloxy-4-methoxy-phe...)
Affinity DataIC50:  500nMAssay Description:Inhibition of LPS-induced TNF-alpha production in human PBMC preincubated for 30 mins followed by LPS addition measured after 5 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM93191(Src SH2 inhibitor, 1f)
Affinity DataIC50:  900nMAssay Description:Compounds were tested for binding to Src SH2 using a fluorescence polarization binding assay according to methods previously described. IC50 values ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM93186(Src SH2 inhibitor, 1a)
Affinity DataIC50:  1.90E+3nMAssay Description:Compounds were tested for binding to Src SH2 using a fluorescence polarization binding assay according to methods previously described. IC50 values ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoblastoma-associated protein(Homo sapiens (Human))
Padmashri Vikhe Patil College Of Arts

Curated by ChEMBL
LigandPNGBDBM50251835(CHEMBL4092194)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of FITC-Bak-BH3 binding to recombinant MBP-fused MCL1 (172 to 318 residues) (unknown origin) in presence of BSA by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoblastoma-associated protein(Homo sapiens (Human))
Padmashri Vikhe Patil College Of Arts

Curated by ChEMBL
LigandPNGBDBM50251835(CHEMBL4092194)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of retinoblastoma protein phosphorylation in human MDA-MB-231 cells after 16 hrs by Hoechst 33342 staining based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoblastoma-associated protein(Homo sapiens (Human))
Padmashri Vikhe Patil College Of Arts

Curated by ChEMBL
LigandPNGBDBM50251836(CHEMBL4070561)
Affinity DataIC50:  2.20E+3nMAssay Description:Inhibition of retinoblastoma protein phosphorylation in human MDA-MB-231 cells after 16 hrs by Hoechst 33342 staining based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM93190(Src SH2 inhibitor, 1e)
Affinity DataIC50:  2.60E+3nMAssay Description:Compounds were tested for binding to Src SH2 using a fluorescence polarization binding assay according to methods previously described. IC50 values ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoblastoma-associated protein(Homo sapiens (Human))
Padmashri Vikhe Patil College Of Arts

Curated by ChEMBL
LigandPNGBDBM50251866(CHEMBL4070208)
Affinity DataIC50:  2.90E+3nMAssay Description:Inhibition of retinoblastoma protein phosphorylation in human MDA-MB-231 cells after 16 hrs by Hoechst 33342 staining based fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetRetinoblastoma-associated protein(Homo sapiens (Human))
Padmashri Vikhe Patil College Of Arts

Curated by ChEMBL
LigandPNGBDBM50251841(CHEMBL4068198)
Affinity DataIC50:  3.50E+3nMAssay Description:Inhibition of retinoblastoma protein phosphorylation in human MDA-MB-231 cells after 16 hrs by Hoechst 33342 staining based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTumor necrosis factor(Homo sapiens (Human))
Padmashri Vikhe Patil College Of Arts

Curated by ChEMBL
LigandPNGBDBM50453998(CHEMBL4206211)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of LPS-induced TNF-alpha production in human PBMC preincubated for 30 mins followed by LPS addition measured after 5 hrs by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTumor necrosis factor(Homo sapiens (Human))
Padmashri Vikhe Patil College Of Arts

Curated by ChEMBL
LigandPNGBDBM50453997(CHEMBL4204861)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of LPS-induced TNF-alpha production in human PBMC preincubated for 30 mins followed by LPS addition measured after 5 hrs by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTumor necrosis factor(Homo sapiens (Human))
Padmashri Vikhe Patil College Of Arts

Curated by ChEMBL
LigandPNGBDBM50454026(CHEMBL4216705)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of LPS-induced TNF-alpha production in human PBMC preincubated for 30 mins followed by LPS addition measured after 5 hrs by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTumor necrosis factor(Homo sapiens (Human))
Padmashri Vikhe Patil College Of Arts

Curated by ChEMBL
LigandPNGBDBM50454032(CHEMBL4209925)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of LPS-induced TNF-alpha production in human PBMC preincubated for 30 mins followed by LPS addition measured after 5 hrs by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetRetinoblastoma-associated protein(Homo sapiens (Human))
Padmashri Vikhe Patil College Of Arts

Curated by ChEMBL
LigandPNGBDBM50251850(CHEMBL4077816)
Affinity DataIC50:  4.10E+3nMAssay Description:Inhibition of retinoblastoma protein phosphorylation in human MDA-MB-231 cells after 16 hrs by Hoechst 33342 staining based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoblastoma-associated protein(Homo sapiens (Human))
Padmashri Vikhe Patil College Of Arts

Curated by ChEMBL
LigandPNGBDBM50251837(CHEMBL4068744)
Affinity DataIC50:  4.81E+3nMAssay Description:Inhibition of retinoblastoma protein phosphorylation in human MDA-MB-231 cells after 16 hrs by Hoechst 33342 staining based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTumor necrosis factor(Homo sapiens (Human))
Padmashri Vikhe Patil College Of Arts

Curated by ChEMBL
LigandPNGBDBM50453995(CHEMBL4212779)
Affinity DataIC50:  6.00E+3nMAssay Description:Inhibition of LPS-induced TNF-alpha production in human PBMC preincubated for 30 mins followed by LPS addition measured after 5 hrs by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50080177((S)-4-{(S)-2-[(S)-2-Acetylamino-3-(4-phosphonooxy-...)
Affinity DataIC50:  6.00E+3nMAssay Description:Binding affinity against Src-homology 2 (SRC SH2).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTumor necrosis factor(Homo sapiens (Human))
Padmashri Vikhe Patil College Of Arts

Curated by ChEMBL
LigandPNGBDBM50454033(CHEMBL4211218)
Affinity DataIC50:  6.00E+3nMAssay Description:Inhibition of LPS-induced TNF-alpha production in human PBMC preincubated for 30 mins followed by LPS addition measured after 5 hrs by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM93192(Src SH2 inhibitor, 1g)
Affinity DataIC50:  6.50E+3nMAssay Description:Compounds were tested for binding to Src SH2 using a fluorescence polarization binding assay according to methods previously described. IC50 values ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM93194(Src SH2 inhibitor, 3)
Affinity DataIC50:  6.50E+3nMAssay Description:Compounds were tested for binding to Src SH2 using a fluorescence polarization binding assay according to methods previously described. IC50 values ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoblastoma-associated protein(Homo sapiens (Human))
Padmashri Vikhe Patil College Of Arts

Curated by ChEMBL
LigandPNGBDBM50251834(CHEMBL4061653)
Affinity DataIC50:  6.92E+3nMAssay Description:Inhibition of retinoblastoma protein phosphorylation in human MDA-MB-231 cells after 16 hrs by Hoechst 33342 staining based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50080198((S)-4-[(S)-2-Acetylamino-3-(4-phosphonooxy-phenyl)...)
Affinity DataIC50:  7.00E+3nMAssay Description:Binding affinity against Src-homology 2 (SRC SH2).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTumor necrosis factor(Homo sapiens (Human))
Padmashri Vikhe Patil College Of Arts

Curated by ChEMBL
LigandPNGBDBM50453993(CHEMBL4206607)
Affinity DataIC50:  7.00E+3nMAssay Description:Inhibition of LPS-induced TNF-alpha production in human PBMC preincubated for 30 mins followed by LPS addition measured after 5 hrs by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEnoyl-acyl carrier reductase(Plasmodium falciparum)
Bombay College Of Pharmacy

LigandPNGBDBM97424(Phenylaminoacetic acid benzylidene hydrazine analo...)
Affinity DataIC50:  7.00E+3nMpH: 7.4Assay Description:Inhibition assay using pfENR.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM93189(Src SH2 inhibitor, 1d)
Affinity DataIC50:  7.50E+3nMAssay Description:Compounds were tested for binding to Src SH2 using a fluorescence polarization binding assay according to methods previously described. IC50 values ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50080193((S)-4-[(S)-2-Acetylamino-3-(4-phosphonooxy-phenyl)...)
Affinity DataIC50:  8.00E+3nMAssay Description:Binding affinity against Src-homology 2 (SRC SH2).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTumor necrosis factor(Homo sapiens (Human))
Padmashri Vikhe Patil College Of Arts

Curated by ChEMBL
LigandPNGBDBM50453988(CHEMBL4202770)
Affinity DataIC50:  8.00E+3nMAssay Description:Inhibition of LPS-induced TNF-alpha production in human PBMC preincubated for 30 mins followed by LPS addition measured after 5 hrs by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEnoyl-acyl carrier reductase(Plasmodium falciparum)
Bombay College Of Pharmacy

LigandPNGBDBM97414(Phenylaminoacetic acid benzylidene hydrazine analo...)
Affinity DataIC50:  8.00E+3nMpH: 7.4Assay Description:Inhibition assay using pfENR.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTumor necrosis factor(Homo sapiens (Human))
Padmashri Vikhe Patil College Of Arts

Curated by ChEMBL
LigandPNGBDBM50454006(CHEMBL4213788)
Affinity DataIC50:  9.00E+3nMAssay Description:Inhibition of LPS-induced TNF-alpha production in human PBMC preincubated for 30 mins followed by LPS addition measured after 5 hrs by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetRetinoblastoma-associated protein(Homo sapiens (Human))
Padmashri Vikhe Patil College Of Arts

Curated by ChEMBL
LigandPNGBDBM50251779(CHEMBL4076325)
Affinity DataIC50:  9.20E+3nMAssay Description:Inhibition of retinoblastoma protein phosphorylation in human MDA-MB-231 cells after 16 hrs by Hoechst 33342 staining based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoblastoma-associated protein(Homo sapiens (Human))
Padmashri Vikhe Patil College Of Arts

Curated by ChEMBL
LigandPNGBDBM50251809(CHEMBL4075949)
Affinity DataIC50:  9.50E+3nMAssay Description:Inhibition of retinoblastoma protein phosphorylation in human MDA-MB-231 cells after 16 hrs by Hoechst 33342 staining based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoblastoma-associated protein(Homo sapiens (Human))
Padmashri Vikhe Patil College Of Arts

Curated by ChEMBL
LigandPNGBDBM50251767(CHEMBL4092469)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of FITC-Bak-BH3 binding to recombinant MBP-fused MCL1 (172 to 318 residues) (unknown origin) in presence of 1% FBS by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetRetinoblastoma-associated protein(Homo sapiens (Human))
Padmashri Vikhe Patil College Of Arts

Curated by ChEMBL
LigandPNGBDBM50251781(CHEMBL4075814)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of retinoblastoma protein phosphorylation in human MDA-MB-231 cells after 16 hrs by Hoechst 33342 staining based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoblastoma-associated protein(Homo sapiens (Human))
Padmashri Vikhe Patil College Of Arts

Curated by ChEMBL
LigandPNGBDBM50251767(CHEMBL4092469)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of retinoblastoma protein phosphorylation in human MDA-MB-231 cells after 16 hrs by Hoechst 33342 staining based fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEnoyl-acyl carrier reductase(Plasmodium falciparum)
Bombay College Of Pharmacy

LigandPNGBDBM97412(Phenylaminoacetic acid benzylidene hydrazine analo...)
Affinity DataIC50:  1.00E+4nMpH: 7.4Assay Description:Inhibition assay using pfENR.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoblastoma-associated protein(Homo sapiens (Human))
Padmashri Vikhe Patil College Of Arts

Curated by ChEMBL
LigandPNGBDBM50251843(CHEMBL4064772)
Affinity DataIC50:  1.10E+4nMAssay Description:Inhibition of retinoblastoma protein phosphorylation in human MDA-MB-231 cells after 16 hrs by Hoechst 33342 staining based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTumor necrosis factor(Homo sapiens (Human))
Padmashri Vikhe Patil College Of Arts

Curated by ChEMBL
LigandPNGBDBM50453991(CHEMBL4211883)
Affinity DataIC50:  1.10E+4nMAssay Description:Inhibition of LPS-induced TNF-alpha production in human PBMC preincubated for 30 mins followed by LPS addition measured after 5 hrs by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTumor necrosis factor(Homo sapiens (Human))
Padmashri Vikhe Patil College Of Arts

Curated by ChEMBL
LigandPNGBDBM50454000(CHEMBL4204753)
Affinity DataIC50:  1.10E+4nMAssay Description:Inhibition of LPS-induced TNF-alpha production in human PBMC preincubated for 30 mins followed by LPS addition measured after 5 hrs by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTumor necrosis factor(Homo sapiens (Human))
Padmashri Vikhe Patil College Of Arts

Curated by ChEMBL
LigandPNGBDBM50453990(CHEMBL4209097)
Affinity DataIC50:  1.10E+4nMAssay Description:Inhibition of LPS-induced TNF-alpha production in human PBMC preincubated for 30 mins followed by LPS addition measured after 5 hrs by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50080179(CHEMBL80765 | Phosphoric acid mono-(4-{(S)-2-acety...)
Affinity DataIC50:  1.20E+4nMAssay Description:Binding affinity against Src-homology 2 (SRC SH2).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTumor necrosis factor(Homo sapiens (Human))
Padmashri Vikhe Patil College Of Arts

Curated by ChEMBL
LigandPNGBDBM50454028(CHEMBL4216431)
Affinity DataIC50:  1.20E+4nMAssay Description:Inhibition of LPS-induced TNF-alpha production in human PBMC preincubated for 30 mins followed by LPS addition measured after 5 hrs by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTumor necrosis factor(Homo sapiens (Human))
Padmashri Vikhe Patil College Of Arts

Curated by ChEMBL
LigandPNGBDBM50453992(CHEMBL4216524)
Affinity DataIC50:  1.20E+4nMAssay Description:Inhibition of LPS-induced TNF-alpha production in human PBMC preincubated for 30 mins followed by LPS addition measured after 5 hrs by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEnoyl-acyl carrier reductase(Plasmodium falciparum)
Bombay College Of Pharmacy

LigandPNGBDBM97413(Phenylaminoacetic acid benzylidene hydrazine analo...)
Affinity DataIC50:  1.20E+4nMpH: 7.4Assay Description:Inhibition assay using pfENR.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50080186(CHEMBL77702 | Phosphoric acid mono-(4-{(S)-2-acety...)
Affinity DataIC50:  1.40E+4nMAssay Description:Binding affinity against Src-homology 2 (SRC SH2).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoblastoma-associated protein(Homo sapiens (Human))
Padmashri Vikhe Patil College Of Arts

Curated by ChEMBL
LigandPNGBDBM50251761(CHEMBL4071674)
Affinity DataIC50:  1.50E+4nMAssay Description:Inhibition of retinoblastoma protein phosphorylation in human MDA-MB-231 cells after 16 hrs by Hoechst 33342 staining based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Displayed 1 to 50 (of 138 total ) | Next | Last >>
Jump to: