Affinity DataIC50: 49nMpH: 7.4Assay Description:Inhibition assay using pfENR.More data for this Ligand-Target Pair
TargetRetinoblastoma-associated protein(Homo sapiens (Human))
Padmashri Vikhe Patil College Of Arts
Curated by ChEMBL
Padmashri Vikhe Patil College Of Arts
Curated by ChEMBL
Affinity DataIC50: 66nMAssay Description:Inhibition of retinoblastoma protein phosphorylation in human MDA-MB-231 cells after 16 hrs by Hoechst 33342 staining based fluorescence assayMore data for this Ligand-Target Pair
TargetTumor necrosis factor(Homo sapiens (Human))
Padmashri Vikhe Patil College Of Arts
Curated by ChEMBL
Padmashri Vikhe Patil College Of Arts
Curated by ChEMBL
Affinity DataIC50: 200nMAssay Description:Inhibition of LPS-induced TNF-alpha production in human MNC suspension after 20 hrs by radioimmunoassayMore data for this Ligand-Target Pair
TargetTumor necrosis factor(Homo sapiens (Human))
Padmashri Vikhe Patil College Of Arts
Curated by ChEMBL
Padmashri Vikhe Patil College Of Arts
Curated by ChEMBL
Affinity DataIC50: 300nMAssay Description:Inhibition of LPS-induced TNF-alpha production in human PBMC preincubated for 30 mins followed by LPS addition measured after 5 hrs by ELISAMore data for this Ligand-Target Pair
TargetTumor necrosis factor(Homo sapiens (Human))
Padmashri Vikhe Patil College Of Arts
Curated by ChEMBL
Padmashri Vikhe Patil College Of Arts
Curated by ChEMBL
Affinity DataIC50: 500nMAssay Description:Inhibition of LPS-induced TNF-alpha production in human PBMC preincubated for 30 mins followed by LPS addition measured after 5 hrs by ELISAMore data for this Ligand-Target Pair
TargetTumor necrosis factor(Homo sapiens (Human))
Padmashri Vikhe Patil College Of Arts
Curated by ChEMBL
Padmashri Vikhe Patil College Of Arts
Curated by ChEMBL
Affinity DataIC50: 500nMAssay Description:Inhibition of LPS-induced TNF-alpha production in human PBMC preincubated for 30 mins followed by LPS addition measured after 5 hrs by ELISAMore data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src/SH2 domain-containing adapter protein B(Homo sapiens (Human))
Ariad Pharmaceuticals
Ariad Pharmaceuticals
Affinity DataIC50: 900nMAssay Description:Compounds were tested for binding to Src SH2 using a fluorescence polarization binding assay according to methods previously described. IC50 values ...More data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src/SH2 domain-containing adapter protein B(Homo sapiens (Human))
Ariad Pharmaceuticals
Ariad Pharmaceuticals
Affinity DataIC50: 1.90E+3nMAssay Description:Compounds were tested for binding to Src SH2 using a fluorescence polarization binding assay according to methods previously described. IC50 values ...More data for this Ligand-Target Pair
TargetRetinoblastoma-associated protein(Homo sapiens (Human))
Padmashri Vikhe Patil College Of Arts
Curated by ChEMBL
Padmashri Vikhe Patil College Of Arts
Curated by ChEMBL
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of FITC-Bak-BH3 binding to recombinant MBP-fused MCL1 (172 to 318 residues) (unknown origin) in presence of BSA by TR-FRET assayMore data for this Ligand-Target Pair
TargetRetinoblastoma-associated protein(Homo sapiens (Human))
Padmashri Vikhe Patil College Of Arts
Curated by ChEMBL
Padmashri Vikhe Patil College Of Arts
Curated by ChEMBL
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of retinoblastoma protein phosphorylation in human MDA-MB-231 cells after 16 hrs by Hoechst 33342 staining based fluorescence assayMore data for this Ligand-Target Pair
TargetRetinoblastoma-associated protein(Homo sapiens (Human))
Padmashri Vikhe Patil College Of Arts
Curated by ChEMBL
Padmashri Vikhe Patil College Of Arts
Curated by ChEMBL
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of retinoblastoma protein phosphorylation in human MDA-MB-231 cells after 16 hrs by Hoechst 33342 staining based fluorescence assayMore data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src/SH2 domain-containing adapter protein B(Homo sapiens (Human))
Ariad Pharmaceuticals
Ariad Pharmaceuticals
Affinity DataIC50: 2.60E+3nMAssay Description:Compounds were tested for binding to Src SH2 using a fluorescence polarization binding assay according to methods previously described. IC50 values ...More data for this Ligand-Target Pair
TargetRetinoblastoma-associated protein(Homo sapiens (Human))
Padmashri Vikhe Patil College Of Arts
Curated by ChEMBL
Padmashri Vikhe Patil College Of Arts
Curated by ChEMBL
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition of retinoblastoma protein phosphorylation in human MDA-MB-231 cells after 16 hrs by Hoechst 33342 staining based fluorescence assayMore data for this Ligand-Target Pair
TargetRetinoblastoma-associated protein(Homo sapiens (Human))
Padmashri Vikhe Patil College Of Arts
Curated by ChEMBL
Padmashri Vikhe Patil College Of Arts
Curated by ChEMBL
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of retinoblastoma protein phosphorylation in human MDA-MB-231 cells after 16 hrs by Hoechst 33342 staining based fluorescence assayMore data for this Ligand-Target Pair
TargetTumor necrosis factor(Homo sapiens (Human))
Padmashri Vikhe Patil College Of Arts
Curated by ChEMBL
Padmashri Vikhe Patil College Of Arts
Curated by ChEMBL
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of LPS-induced TNF-alpha production in human PBMC preincubated for 30 mins followed by LPS addition measured after 5 hrs by ELISAMore data for this Ligand-Target Pair
TargetTumor necrosis factor(Homo sapiens (Human))
Padmashri Vikhe Patil College Of Arts
Curated by ChEMBL
Padmashri Vikhe Patil College Of Arts
Curated by ChEMBL
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of LPS-induced TNF-alpha production in human PBMC preincubated for 30 mins followed by LPS addition measured after 5 hrs by ELISAMore data for this Ligand-Target Pair
TargetTumor necrosis factor(Homo sapiens (Human))
Padmashri Vikhe Patil College Of Arts
Curated by ChEMBL
Padmashri Vikhe Patil College Of Arts
Curated by ChEMBL
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of LPS-induced TNF-alpha production in human PBMC preincubated for 30 mins followed by LPS addition measured after 5 hrs by ELISAMore data for this Ligand-Target Pair
TargetTumor necrosis factor(Homo sapiens (Human))
Padmashri Vikhe Patil College Of Arts
Curated by ChEMBL
Padmashri Vikhe Patil College Of Arts
Curated by ChEMBL
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of LPS-induced TNF-alpha production in human PBMC preincubated for 30 mins followed by LPS addition measured after 5 hrs by ELISAMore data for this Ligand-Target Pair
TargetRetinoblastoma-associated protein(Homo sapiens (Human))
Padmashri Vikhe Patil College Of Arts
Curated by ChEMBL
Padmashri Vikhe Patil College Of Arts
Curated by ChEMBL
Affinity DataIC50: 4.10E+3nMAssay Description:Inhibition of retinoblastoma protein phosphorylation in human MDA-MB-231 cells after 16 hrs by Hoechst 33342 staining based fluorescence assayMore data for this Ligand-Target Pair
TargetRetinoblastoma-associated protein(Homo sapiens (Human))
Padmashri Vikhe Patil College Of Arts
Curated by ChEMBL
Padmashri Vikhe Patil College Of Arts
Curated by ChEMBL
Affinity DataIC50: 4.81E+3nMAssay Description:Inhibition of retinoblastoma protein phosphorylation in human MDA-MB-231 cells after 16 hrs by Hoechst 33342 staining based fluorescence assayMore data for this Ligand-Target Pair
TargetTumor necrosis factor(Homo sapiens (Human))
Padmashri Vikhe Patil College Of Arts
Curated by ChEMBL
Padmashri Vikhe Patil College Of Arts
Curated by ChEMBL
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of LPS-induced TNF-alpha production in human PBMC preincubated for 30 mins followed by LPS addition measured after 5 hrs by ELISAMore data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Ariad Pharmaceuticals
Curated by ChEMBL
Ariad Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 6.00E+3nMAssay Description:Binding affinity against Src-homology 2 (SRC SH2).More data for this Ligand-Target Pair
TargetTumor necrosis factor(Homo sapiens (Human))
Padmashri Vikhe Patil College Of Arts
Curated by ChEMBL
Padmashri Vikhe Patil College Of Arts
Curated by ChEMBL
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of LPS-induced TNF-alpha production in human PBMC preincubated for 30 mins followed by LPS addition measured after 5 hrs by ELISAMore data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src/SH2 domain-containing adapter protein B(Homo sapiens (Human))
Ariad Pharmaceuticals
Ariad Pharmaceuticals
Affinity DataIC50: 6.50E+3nMAssay Description:Compounds were tested for binding to Src SH2 using a fluorescence polarization binding assay according to methods previously described. IC50 values ...More data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src/SH2 domain-containing adapter protein B(Homo sapiens (Human))
Ariad Pharmaceuticals
Ariad Pharmaceuticals
Affinity DataIC50: 6.50E+3nMAssay Description:Compounds were tested for binding to Src SH2 using a fluorescence polarization binding assay according to methods previously described. IC50 values ...More data for this Ligand-Target Pair
TargetRetinoblastoma-associated protein(Homo sapiens (Human))
Padmashri Vikhe Patil College Of Arts
Curated by ChEMBL
Padmashri Vikhe Patil College Of Arts
Curated by ChEMBL
Affinity DataIC50: 6.92E+3nMAssay Description:Inhibition of retinoblastoma protein phosphorylation in human MDA-MB-231 cells after 16 hrs by Hoechst 33342 staining based fluorescence assayMore data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Ariad Pharmaceuticals
Curated by ChEMBL
Ariad Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 7.00E+3nMAssay Description:Binding affinity against Src-homology 2 (SRC SH2).More data for this Ligand-Target Pair
TargetTumor necrosis factor(Homo sapiens (Human))
Padmashri Vikhe Patil College Of Arts
Curated by ChEMBL
Padmashri Vikhe Patil College Of Arts
Curated by ChEMBL
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of LPS-induced TNF-alpha production in human PBMC preincubated for 30 mins followed by LPS addition measured after 5 hrs by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 7.00E+3nMpH: 7.4Assay Description:Inhibition assay using pfENR.More data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src/SH2 domain-containing adapter protein B(Homo sapiens (Human))
Ariad Pharmaceuticals
Ariad Pharmaceuticals
Affinity DataIC50: 7.50E+3nMAssay Description:Compounds were tested for binding to Src SH2 using a fluorescence polarization binding assay according to methods previously described. IC50 values ...More data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Ariad Pharmaceuticals
Curated by ChEMBL
Ariad Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 8.00E+3nMAssay Description:Binding affinity against Src-homology 2 (SRC SH2).More data for this Ligand-Target Pair
TargetTumor necrosis factor(Homo sapiens (Human))
Padmashri Vikhe Patil College Of Arts
Curated by ChEMBL
Padmashri Vikhe Patil College Of Arts
Curated by ChEMBL
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of LPS-induced TNF-alpha production in human PBMC preincubated for 30 mins followed by LPS addition measured after 5 hrs by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 8.00E+3nMpH: 7.4Assay Description:Inhibition assay using pfENR.More data for this Ligand-Target Pair
TargetTumor necrosis factor(Homo sapiens (Human))
Padmashri Vikhe Patil College Of Arts
Curated by ChEMBL
Padmashri Vikhe Patil College Of Arts
Curated by ChEMBL
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of LPS-induced TNF-alpha production in human PBMC preincubated for 30 mins followed by LPS addition measured after 5 hrs by ELISAMore data for this Ligand-Target Pair
TargetRetinoblastoma-associated protein(Homo sapiens (Human))
Padmashri Vikhe Patil College Of Arts
Curated by ChEMBL
Padmashri Vikhe Patil College Of Arts
Curated by ChEMBL
Affinity DataIC50: 9.20E+3nMAssay Description:Inhibition of retinoblastoma protein phosphorylation in human MDA-MB-231 cells after 16 hrs by Hoechst 33342 staining based fluorescence assayMore data for this Ligand-Target Pair
TargetRetinoblastoma-associated protein(Homo sapiens (Human))
Padmashri Vikhe Patil College Of Arts
Curated by ChEMBL
Padmashri Vikhe Patil College Of Arts
Curated by ChEMBL
Affinity DataIC50: 9.50E+3nMAssay Description:Inhibition of retinoblastoma protein phosphorylation in human MDA-MB-231 cells after 16 hrs by Hoechst 33342 staining based fluorescence assayMore data for this Ligand-Target Pair
TargetRetinoblastoma-associated protein(Homo sapiens (Human))
Padmashri Vikhe Patil College Of Arts
Curated by ChEMBL
Padmashri Vikhe Patil College Of Arts
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of FITC-Bak-BH3 binding to recombinant MBP-fused MCL1 (172 to 318 residues) (unknown origin) in presence of 1% FBS by TR-FRET assayMore data for this Ligand-Target Pair
TargetRetinoblastoma-associated protein(Homo sapiens (Human))
Padmashri Vikhe Patil College Of Arts
Curated by ChEMBL
Padmashri Vikhe Patil College Of Arts
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of retinoblastoma protein phosphorylation in human MDA-MB-231 cells after 16 hrs by Hoechst 33342 staining based fluorescence assayMore data for this Ligand-Target Pair
TargetRetinoblastoma-associated protein(Homo sapiens (Human))
Padmashri Vikhe Patil College Of Arts
Curated by ChEMBL
Padmashri Vikhe Patil College Of Arts
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of retinoblastoma protein phosphorylation in human MDA-MB-231 cells after 16 hrs by Hoechst 33342 staining based fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMpH: 7.4Assay Description:Inhibition assay using pfENR.More data for this Ligand-Target Pair
TargetRetinoblastoma-associated protein(Homo sapiens (Human))
Padmashri Vikhe Patil College Of Arts
Curated by ChEMBL
Padmashri Vikhe Patil College Of Arts
Curated by ChEMBL
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of retinoblastoma protein phosphorylation in human MDA-MB-231 cells after 16 hrs by Hoechst 33342 staining based fluorescence assayMore data for this Ligand-Target Pair
TargetTumor necrosis factor(Homo sapiens (Human))
Padmashri Vikhe Patil College Of Arts
Curated by ChEMBL
Padmashri Vikhe Patil College Of Arts
Curated by ChEMBL
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of LPS-induced TNF-alpha production in human PBMC preincubated for 30 mins followed by LPS addition measured after 5 hrs by ELISAMore data for this Ligand-Target Pair
TargetTumor necrosis factor(Homo sapiens (Human))
Padmashri Vikhe Patil College Of Arts
Curated by ChEMBL
Padmashri Vikhe Patil College Of Arts
Curated by ChEMBL
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of LPS-induced TNF-alpha production in human PBMC preincubated for 30 mins followed by LPS addition measured after 5 hrs by ELISAMore data for this Ligand-Target Pair
TargetTumor necrosis factor(Homo sapiens (Human))
Padmashri Vikhe Patil College Of Arts
Curated by ChEMBL
Padmashri Vikhe Patil College Of Arts
Curated by ChEMBL
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of LPS-induced TNF-alpha production in human PBMC preincubated for 30 mins followed by LPS addition measured after 5 hrs by ELISAMore data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Ariad Pharmaceuticals
Curated by ChEMBL
Ariad Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 1.20E+4nMAssay Description:Binding affinity against Src-homology 2 (SRC SH2).More data for this Ligand-Target Pair
TargetTumor necrosis factor(Homo sapiens (Human))
Padmashri Vikhe Patil College Of Arts
Curated by ChEMBL
Padmashri Vikhe Patil College Of Arts
Curated by ChEMBL
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of LPS-induced TNF-alpha production in human PBMC preincubated for 30 mins followed by LPS addition measured after 5 hrs by ELISAMore data for this Ligand-Target Pair
TargetTumor necrosis factor(Homo sapiens (Human))
Padmashri Vikhe Patil College Of Arts
Curated by ChEMBL
Padmashri Vikhe Patil College Of Arts
Curated by ChEMBL
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of LPS-induced TNF-alpha production in human PBMC preincubated for 30 mins followed by LPS addition measured after 5 hrs by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 1.20E+4nMpH: 7.4Assay Description:Inhibition assay using pfENR.More data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Ariad Pharmaceuticals
Curated by ChEMBL
Ariad Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 1.40E+4nMAssay Description:Binding affinity against Src-homology 2 (SRC SH2).More data for this Ligand-Target Pair
TargetRetinoblastoma-associated protein(Homo sapiens (Human))
Padmashri Vikhe Patil College Of Arts
Curated by ChEMBL
Padmashri Vikhe Patil College Of Arts
Curated by ChEMBL
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of retinoblastoma protein phosphorylation in human MDA-MB-231 cells after 16 hrs by Hoechst 33342 staining based fluorescence assayMore data for this Ligand-Target Pair