Compile Data Set for Download or QSAR
maximum 50k data
Found 100 with Last Name = 'kim' and Initial = 'by'
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Silla University

Curated by ChEMBL
LigandPNGBDBM50311254(2-hydroxy-4-(2-hydroxy-6-pentadecyl-4-((2S,3R,4S,5...)
Affinity DataKi:  100nMAssay Description:Competitive inhibition of PTP1B mediated pNPP hydrolysis by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Silla University

Curated by ChEMBL
LigandPNGBDBM50104694((R)-4-hydroxy-5-(hydroxymethyl)-3-palmitoylfuran-2...)
Affinity DataIC50:  4.5nMAssay Description:Inhibition of human recombinant PTP1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Korea Basic Science Institute

Curated by ChEMBL
LigandPNGBDBM50433414(CHEMBL2380650)
Affinity DataIC50:  120nMAssay Description:Inhibition of HA-EGFP tagged Plk1 polo-box domain (unknown origin) expressed in 293A cells assessed as inhibition of biotin-p-T78 binding after 1 hr ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Silla University

Curated by ChEMBL
LigandPNGBDBM50311254(2-hydroxy-4-(2-hydroxy-6-pentadecyl-4-((2S,3R,4S,5...)
Affinity DataIC50:  190nMAssay Description:Inhibition of PTP1B mediated pNPP hydrolysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Silla University

Curated by ChEMBL
LigandPNGBDBM50311256(4-(2,4-dihydroxy-6-pentadecylbenzoyloxy)-2-hydroxy...)
Affinity DataIC50:  220nMAssay Description:Inhibition of PTP1B mediated pNPP hydrolysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Korea Basic Science Institute

Curated by ChEMBL
LigandPNGBDBM50554673(CHEMBL4760204)
Affinity DataIC50:  230nMAssay Description:Displacement of 5-carboxyfluorescein-labeled PBD-binding peptide from PLk1 PBD (unknown origin) expressed in bacterial expression system incubated fo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Korea Research Institute Of Bioscience And Biotechnology

Curated by ChEMBL
LigandPNGBDBM24778(2-methyl-1,4-dihydronaphthalene-1,4-dione | 2-meth...)
Affinity DataIC50:  370nMAssay Description:Inhibition of ascorbic acid/methylene blue activated recombinant human IDO expressed in Escherichia coli using L-Tryptophan as substrate after 60 min...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Korea Research Institute Of Bioscience And Biotechnology

Curated by ChEMBL
LigandPNGBDBM50269626(Naphthomycin A)
Affinity DataIC50:  440nMAssay Description:Inhibition of ascorbic acid/methylene blue activated recombinant human IDO expressed in Escherichia coli using L-Tryptophan as substrate after 60 min...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Homo sapiens (Human))
Silla University

Curated by ChEMBL
LigandPNGBDBM50311254(2-hydroxy-4-(2-hydroxy-6-pentadecyl-4-((2S,3R,4S,5...)
Affinity DataIC50:  510nMAssay Description:Inhibition of TCPTPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Korea Research Institute Of Bioscience And Biotechnology

Curated by ChEMBL
LigandPNGBDBM50269632(CHEMBL4126044)
Affinity DataIC50:  560nMAssay Description:Inhibition of ascorbic acid/methylene blue activated recombinant human IDO expressed in Escherichia coli using L-Tryptophan as substrate after 60 min...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Silla University

Curated by ChEMBL
LigandPNGBDBM50311257(2-hydroxy-6-pentadecyl-4-((2S,3R,4S,5S,6R)-3,4,5-t...)
Affinity DataIC50:  590nMAssay Description:Inhibition of PTP1B mediated pNPP hydrolysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Korea Basic Science Institute

Curated by ChEMBL
LigandPNGBDBM50433415(CHEMBL2380764)
Affinity DataIC50:  1.08E+3nMAssay Description:Inhibition of HA-EGFP tagged Plk1 polo-box domain (unknown origin) expressed in 293A cells assessed as inhibition of biotin-p-T78 binding after 1 hr ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Silla University

Curated by ChEMBL
LigandPNGBDBM50179012(CHEMBL382338 | Sanggenon G)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition of PTP1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Silla University

Curated by ChEMBL
LigandPNGBDBM50148911((3beta)-3-hydroxyurs-12-en-28-oic acid | 3beta-hyd...)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibition of PTP1B mediated pNPP hydrolysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Korea Basic Science Institute

Curated by ChEMBL
LigandPNGBDBM50433416(CHEMBL2380660)
Affinity DataIC50:  2.56E+3nMAssay Description:Inhibition of HA-EGFP tagged Plk1 polo-box domain (unknown origin) expressed in 293A cells assessed as inhibition of biotin-p-T78 binding after 1 hr ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Silla University

Curated by ChEMBL
LigandPNGBDBM50179008(CHEMBL204813 | sanggenon C)
Affinity DataIC50:  2.60E+3nMAssay Description:Inhibition of PTP1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Silla University

Curated by ChEMBL
LigandPNGBDBM50148911((3beta)-3-hydroxyurs-12-en-28-oic acid | 3beta-hyd...)
Affinity DataIC50:  3.60E+3nMAssay Description:Inhibition of human recombinant PTP1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Silla University

Curated by ChEMBL
LigandPNGBDBM50346601(NSC-114945 | OLEANOLIC_ACID | Oleanolic acid | Ole...)
Affinity DataIC50:  3.90E+3nMAssay Description:Inhibition of human recombinant PTP1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Silla University

Curated by ChEMBL
LigandPNGBDBM50104694((R)-4-hydroxy-5-(hydroxymethyl)-3-palmitoylfuran-2...)
Affinity DataIC50:  4.50E+3nMAssay Description:Inhibition of PTP1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Silla University

Curated by ChEMBL
LigandPNGBDBM50104694((R)-4-hydroxy-5-(hydroxymethyl)-3-palmitoylfuran-2...)
Affinity DataIC50:  4.50E+3nMAssay Description:Inhibition of human recombinant PTP1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Silla University

Curated by ChEMBL
LigandPNGBDBM50104694((R)-4-hydroxy-5-(hydroxymethyl)-3-palmitoylfuran-2...)
Affinity DataIC50:  4.50E+3nMAssay Description:Inhibition of human recombinant PTP1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Korea Basic Science Institute

Curated by ChEMBL
LigandPNGBDBM50433413(CHEMBL2380651)
Affinity DataIC50:  4.75E+3nMAssay Description:Inhibition of HA-EGFP tagged Plk1 polo-box domain (unknown origin) expressed in 293A cells assessed as inhibition of biotin-p-T78 binding after 1 hr ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Silla University

Curated by ChEMBL
LigandPNGBDBM50179010(CHEMBL378806 | CVD-0019900 | Mulberrofuran C)
Affinity DataIC50:  4.90E+3nMAssay Description:Inhibition of PTP1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Silla University

Curated by ChEMBL
LigandPNGBDBM50185123(3beta-hydroxyurs-12-en-27-oic acid | CHEMBL380467)
Affinity DataIC50:  4.90E+3nMAssay Description:Inhibition of human recombinant PTP1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Silla University

Curated by ChEMBL
LigandPNGBDBM50185131(3beta-hydroxyolean-12-en-27-oic acid | CHEMBL21097...)
Affinity DataIC50:  5.20E+3nMAssay Description:Inhibition of human recombinant PTP1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Silla University

Curated by ChEMBL
LigandPNGBDBM50370716(CHEMBL1081157)
Affinity DataIC50:  6.80E+3nMAssay Description:Inhibition of human recombinant PTP1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Silla University

Curated by ChEMBL
LigandPNGBDBM50184543(16-alphaH,17-isovaleryloxy-ent-kauran-19-oic acid ...)
Affinity DataIC50:  7.10E+3nMAssay Description:Inhibition of human recombinant PTP1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Silla University

Curated by ChEMBL
LigandPNGBDBM50185122(3beta-acetoxyolean-12-en-27-oic acid | CHEMBL20863...)
Affinity DataIC50:  8.50E+3nMAssay Description:Inhibition of human recombinant PTP1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Korea Basic Science Institute

Curated by ChEMBL
LigandPNGBDBM50433417(CHEMBL2380653)
Affinity DataIC50:  8.50E+3nMAssay Description:Inhibition of HA-EGFP tagged Plk1 polo-box domain (unknown origin) expressed in 293A cells assessed as inhibition of biotin-p-T78 binding after 1 hr ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50269158(3-beta-hydroxy-27-p-(E)-coumaroyloxyurs-12-en-28-o...)
Affinity DataIC50:  9.50E+3nMAssay Description:Inhibition of PLCgamma1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Korea Basic Science Institute

Curated by ChEMBL
LigandPNGBDBM50433418(CHEMBL2380765)
Affinity DataIC50:  9.80E+3nMAssay Description:Inhibition of HA-EGFP tagged Plk1 polo-box domain (unknown origin) expressed in 293A cells assessed as inhibition of biotin-p-T78 binding after 1 hr ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein phosphatase 3(Homo sapiens (Human))
Korea Research Institute Of Bioscience And Biotechnology (Kribb)

Curated by ChEMBL
LigandPNGBDBM50104694((R)-4-hydroxy-5-(hydroxymethyl)-3-palmitoylfuran-2...)
Affinity DataIC50:  1.02E+4nMAssay Description:Inhibition of VHR DS-PTPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Silla University

Curated by ChEMBL
LigandPNGBDBM50185120(3alpha,24-dihydroxyolean-12-en-27-oic acid | CHEMB...)
Affinity DataIC50:  1.17E+4nMAssay Description:Inhibition of human recombinant PTP1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Silla University

Curated by ChEMBL
LigandPNGBDBM50185125(3beta,6beta-dihydroxyolean-12-en-27-oic acid | CHE...)
Affinity DataIC50:  1.28E+4nMAssay Description:Inhibition of human recombinant PTP1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty acid synthase(Homo sapiens (Human))
Korea Research Institute Of Bioscience And Biotechnology

Curated by ChEMBL
LigandPNGBDBM50009248((2R,3S)-3-((4E,7E)-Nona-4,7-dienoyl)-oxirane-2-car...)
Affinity DataIC50:  1.30E+4nMAssay Description:Inhibition of FASMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Silla University

Curated by ChEMBL
LigandPNGBDBM23195((2S,4aS,6aS,6bR,10S,12aS,12bR,14bR)-10-hydroxy-2,4...)
Affinity DataIC50:  1.38E+4nMAssay Description:Inhibition of human recombinant PTP1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Silla University

Curated by ChEMBL
LigandPNGBDBM50185124(CHEMBL381707 | methyl 3beta-hydroxyolean-12-en-28-...)
Affinity DataIC50:  1.42E+4nMAssay Description:Inhibition of human recombinant PTP1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50269154(3-beta-hydroxy-27-(E)-feruloyloxyurs-12-en-28-oic ...)
Affinity DataIC50:  1.43E+4nMAssay Description:Inhibition of PLCgamma1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Silla University

Curated by ChEMBL
LigandPNGBDBM50241807(CHEMBL470865 | abyssinone-VI-4-O-methyl ether)
Affinity DataIC50:  1.48E+4nMAssay Description:Inhibition of human recombinant PTP1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Silla University

Curated by ChEMBL
LigandPNGBDBM50185128(18alpha-Glycyrrhetic acid | CHEMBL378653)
Affinity DataIC50:  1.56E+4nMAssay Description:Inhibition of human recombinant PTP1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Silla University

Curated by ChEMBL
LigandPNGBDBM50241806(CHEMBL470454 | abyssinone IV | abyssinone-IV)
Affinity DataIC50:  1.60E+4nMAssay Description:Inhibition of human recombinant PTP1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Silla University

Curated by ChEMBL
LigandPNGBDBM50185130(CHEMBL207494 | methyl3beta-hydroxyolean-12-en-27-o...)
Affinity DataIC50:  1.60E+4nMAssay Description:Inhibition of human recombinant PTP1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Korea Basic Science Institute

Curated by ChEMBL
LigandPNGBDBM50554676(CHEMBL4788427)
Affinity DataIC50:  1.64E+4nMAssay Description:Displacement of 5-carboxyfluorescein-labeled PBD-binding peptide from PLk1 PBD (unknown origin) expressed in bacterial expression system incubated fo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Silla University

Curated by ChEMBL
LigandPNGBDBM50179009(CHEMBL377937 | Kuwanon L)
Affinity DataIC50:  1.69E+4nMAssay Description:Inhibition of PTP1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Silla University

Curated by ChEMBL
LigandPNGBDBM50311255(3-hydroxy-4-(methoxycarbonyl)-5-methylphenyl 2-hyd...)
Affinity DataIC50:  1.70E+4nMAssay Description:Inhibition of PTP1B mediated pNPP hydrolysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Silla University

Curated by ChEMBL
LigandPNGBDBM50370742(KAURENOIC ACID)
Affinity DataIC50:  2.02E+4nMAssay Description:Inhibition of human recombinant PTP1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Silla University

Curated by ChEMBL
LigandPNGBDBM50241797(CHEMBL470452 | abyssinone-IV-4'-O-methyl ether)
Affinity DataIC50:  2.12E+4nMAssay Description:Inhibition of human recombinant PTP1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50269156(3-beta-hydroxy-27-p-(E)-coumaroyloxyolean-12-en-28...)
Affinity DataIC50:  2.20E+4nMAssay Description:Inhibition of PLCgamma1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty acid synthase(Homo sapiens (Human))
Korea Research Institute Of Bioscience And Biotechnology

Curated by ChEMBL
LigandPNGBDBM50191684(CHEMBL213433 | flavaspidic acid-PB)
Affinity DataIC50:  2.31E+4nMAssay Description:Inhibition of FASMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Silla University

Curated by ChEMBL
LigandPNGBDBM50097211((1R,4aR,7S)-1,4a,7-Trimethyl-7-vinyl-1,2,3,4,4a,6,...)
Affinity DataIC50:  2.35E+4nMAssay Description:Inhibition of human recombinant PTP1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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