Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Korea Research Institute of Chemical Technology
US Patent
Korea Research Institute of Chemical Technology
US Patent
Affinity DataIC50: 0.100nMAssay Description:The in vitro inhibitory activities of the novel compounds to human 11β-HSD1 were evaluated in accordance with homogenous time-resolved fluoresce...More data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Korea Research Institute of Chemical Technology
US Patent
Korea Research Institute of Chemical Technology
US Patent
Affinity DataIC50: 0.200nMAssay Description:The in vitro inhibitory activities of the novel compounds to human 11β-HSD1 were evaluated in accordance with homogenous time-resolved fluoresce...More data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Korea Research Institute of Chemical Technology
US Patent
Korea Research Institute of Chemical Technology
US Patent
Affinity DataIC50: 0.400nMAssay Description:The in vitro inhibitory activities of the novel compounds to human 11β-HSD1 were evaluated in accordance with homogenous time-resolved fluoresce...More data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Korea Research Institute of Chemical Technology
US Patent
Korea Research Institute of Chemical Technology
US Patent
Affinity DataIC50: 0.800nMAssay Description:The in vitro inhibitory activities of the novel compounds to human 11β-HSD1 were evaluated in accordance with homogenous time-resolved fluoresce...More data for this Ligand-Target Pair
TargetTRAF2 and NCK-interacting protein kinase(Homo sapiens (Human))
Korea Research Institute of Chemical Technology
US Patent
Korea Research Institute of Chemical Technology
US Patent
Affinity DataIC50: 1nMAssay Description:The inhibitory properties of compounds were evaluated with TNIK kinase enzyme system and luminescent ADP-GloFigure US11485711-20221101-P00001 Kinase ...More data for this Ligand-Target Pair
TargetTRAF2 and NCK-interacting protein kinase(Homo sapiens (Human))
Korea Research Institute of Chemical Technology
US Patent
Korea Research Institute of Chemical Technology
US Patent
Affinity DataIC50: 1nMAssay Description:The inhibitory properties of compounds were evaluated with TNIK kinase enzyme system and luminescent ADP-GloFigure US11485711-20221101-P00001 Kinase ...More data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Korea Research Institute of Chemical Technology
US Patent
Korea Research Institute of Chemical Technology
US Patent
Affinity DataIC50: 1nMAssay Description:The in vitro inhibitory activities of the novel compounds to human 11β-HSD1 were evaluated in accordance with homogenous time-resolved fluoresce...More data for this Ligand-Target Pair
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of human recombinant DPP4 after 60 mins by fluorescence plate readerMore data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Korea Research Institute of Chemical Technology
US Patent
Korea Research Institute of Chemical Technology
US Patent
Affinity DataIC50: 1nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHO-K1 cells using cortisone as substrate after 3 hrs by HTRF assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in CHO-K1 cells using cortisone as substrate after 3 hrs by HTRF assayMore data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Korea Research Institute of Chemical Technology
US Patent
Korea Research Institute of Chemical Technology
US Patent
Affinity DataIC50: 1nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHO-K1 cells using cortisone as substrate after 3 hrs by HTRF assayMore data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Korea Research Institute of Chemical Technology
US Patent
Korea Research Institute of Chemical Technology
US Patent
Affinity DataIC50: 1nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHO-K1 cells using cortisone as substrate after 3 hrs by HTRF assayMore data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Korea Research Institute of Chemical Technology
US Patent
Korea Research Institute of Chemical Technology
US Patent
Affinity DataIC50: 1nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHO-K1 cells using cortisone as substrate after 3 hrs by HTRF assayMore data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Korea Research Institute of Chemical Technology
US Patent
Korea Research Institute of Chemical Technology
US Patent
Affinity DataIC50: 1nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHO-K1 cells using cortisone as substrate after 3 hrs by HTRF assayMore data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Korea Research Institute of Chemical Technology
US Patent
Korea Research Institute of Chemical Technology
US Patent
Affinity DataIC50: 1nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHOK1 cells using XL665-labeled cortisol as substrate measured after 24 hrs by HTRF assayMore data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Korea Research Institute of Chemical Technology
US Patent
Korea Research Institute of Chemical Technology
US Patent
Affinity DataIC50: 1nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHOK1 cells using XL665-labeled cortisol as substrate measured after 24 hrs by HTRF assayMore data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Korea Research Institute of Chemical Technology
US Patent
Korea Research Institute of Chemical Technology
US Patent
Affinity DataIC50: 1nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHOK1 cells using XL665-labeled cortisol as substrate measured after 24 hrs by HTRF assayMore data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Korea Research Institute of Chemical Technology
US Patent
Korea Research Institute of Chemical Technology
US Patent
Affinity DataIC50: 1nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHOK1 cells using XL665-labeled cortisol as substrate measured after 24 hrs by HTRF assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in CHOK1 cells using XL665-labeled cortisol as substrate measured after 24 hrs by HTRF assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in CHOK1 cells using XL665-labeled cortisol as substrate measured after 24 hrs by HTRF assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in CHOK1 cells using XL665-labeled cortisol as substrate measured after 24 hrs by HTRF assayMore data for this Ligand-Target Pair
TargetTRAF2 and NCK-interacting protein kinase(Homo sapiens (Human))
Korea Research Institute of Chemical Technology
US Patent
Korea Research Institute of Chemical Technology
US Patent
Affinity DataIC50: 1nMAssay Description:The inhibitory properties of compounds were evaluated with TNIK kinase enzyme system and luminescent ADP-GloFigure US11447469-20220920-P00001 Kinase ...More data for this Ligand-Target Pair
TargetTRAF2 and NCK-interacting protein kinase(Homo sapiens (Human))
Korea Research Institute of Chemical Technology
US Patent
Korea Research Institute of Chemical Technology
US Patent
Affinity DataIC50: 1nMAssay Description:The inhibitory properties of compounds were evaluated with TNIK kinase enzyme system and luminescent ADP-GloFigure US11447469-20220920-P00001 Kinase ...More data for this Ligand-Target Pair
TargetTRAF2 and NCK-interacting protein kinase(Homo sapiens (Human))
Korea Research Institute of Chemical Technology
US Patent
Korea Research Institute of Chemical Technology
US Patent
Affinity DataIC50: 1nMAssay Description:The inhibitory properties of compounds were evaluated with TNIK kinase enzyme system and luminescent ADP-GloFigure US11447469-20220920-P00001 Kinase ...More data for this Ligand-Target Pair
TargetTRAF2 and NCK-interacting protein kinase(Homo sapiens (Human))
Korea Research Institute of Chemical Technology
US Patent
Korea Research Institute of Chemical Technology
US Patent
Affinity DataIC50: 1nMAssay Description:The inhibitory properties of compounds were evaluated with TNIK kinase enzyme system and luminescent ADP-GloFigure US11485711-20221101-P00001 Kinase ...More data for this Ligand-Target Pair
TargetTRAF2 and NCK-interacting protein kinase(Homo sapiens (Human))
Korea Research Institute of Chemical Technology
US Patent
Korea Research Institute of Chemical Technology
US Patent
Affinity DataIC50: 1nMAssay Description:The inhibitory properties of compounds were evaluated with TNIK kinase enzyme system and luminescent ADP-GloFigure US11485711-20221101-P00001 Kinase ...More data for this Ligand-Target Pair
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Affinity DataIC50: 1.20nMAssay Description:Inhibition of human recombinant DPP4 after 60 mins by fluorescence plate readerMore data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Korea Research Institute of Chemical Technology
US Patent
Korea Research Institute of Chemical Technology
US Patent
Affinity DataIC50: 1.30nMAssay Description:The in vitro inhibitory activities of the novel compounds to human 11β-HSD1 were evaluated in accordance with homogenous time-resolved fluoresce...More data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Korea Research Institute of Chemical Technology
US Patent
Korea Research Institute of Chemical Technology
US Patent
Affinity DataIC50: 1.70nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHOK1 cells using XL665-labeled cortisol as substrate measured after 24 hrs by HTRF assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in CHO-K1 cells using cortisone as substrate after 3 hrs by HTRF assayMore data for this Ligand-Target Pair
TargetTRAF2 and NCK-interacting protein kinase(Homo sapiens (Human))
Korea Research Institute of Chemical Technology
US Patent
Korea Research Institute of Chemical Technology
US Patent
Affinity DataIC50: 2nMAssay Description:The inhibitory properties of compounds were evaluated with TNIK kinase enzyme system and luminescent ADP-GloFigure US11485711-20221101-P00001 Kinase ...More data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Korea Research Institute of Chemical Technology
US Patent
Korea Research Institute of Chemical Technology
US Patent
Affinity DataIC50: 2nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHO cells after 3 hrs by HTRF cortisol assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in CHOK1 cells using XL665-labeled cortisol as substrate measured after 24 hrs by HTRF assayMore data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Korea Research Institute of Chemical Technology
US Patent
Korea Research Institute of Chemical Technology
US Patent
Affinity DataIC50: 2nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHO cells after 3 hrs by HTRF cortisol assayMore data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1B(Homo sapiens (Human))
Yonsei University
Curated by ChEMBL
Yonsei University
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibition of DYRK1B (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in CHO-K1 cells using cortisone as substrate after 3 hrs by HTRF assayMore data for this Ligand-Target Pair
TargetDiacylglycerol O-acyltransferase 1(Mus musculus (mouse))
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibition of mouse DGAT1 incubated for 60 mins using didecanoyl glycerol and [14C]decanoyl-CoA substrate by liquid scintillation counting and lumino...More data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Korea Research Institute of Chemical Technology
US Patent
Korea Research Institute of Chemical Technology
US Patent
Affinity DataIC50: 3nMAssay Description:The in vitro inhibitory activities of the novel compounds to human 11β-HSD1 were evaluated in accordance with homogenous time-resolved fluoresce...More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1B(Homo sapiens (Human))
Yonsei University
Curated by ChEMBL
Yonsei University
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of DYRK1B (unknown origin)More data for this Ligand-Target Pair
TargetTRAF2 and NCK-interacting protein kinase(Homo sapiens (Human))
Korea Research Institute of Chemical Technology
US Patent
Korea Research Institute of Chemical Technology
US Patent
Affinity DataIC50: 3nMAssay Description:The inhibitory properties of compounds were evaluated with TNIK kinase enzyme system and luminescent ADP-GloFigure US11485711-20221101-P00001 Kinase ...More data for this Ligand-Target Pair
TargetTRAF2 and NCK-interacting protein kinase(Homo sapiens (Human))
Korea Research Institute of Chemical Technology
US Patent
Korea Research Institute of Chemical Technology
US Patent
Affinity DataIC50: 3nMAssay Description:The inhibitory properties of compounds were evaluated with TNIK kinase enzyme system and luminescent ADP-GloFigure US11485711-20221101-P00001 Kinase ...More data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Korea Research Institute of Chemical Technology
US Patent
Korea Research Institute of Chemical Technology
US Patent
Affinity DataIC50: 3nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHO cells after 3 hrs by HTRF cortisol assayMore data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1B(Homo sapiens (Human))
Yonsei University
Curated by ChEMBL
Yonsei University
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of DYRK1B (unknown origin)More data for this Ligand-Target Pair
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of human recombinant DPP4 after 60 mins by fluorescence plate readerMore data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Korea Research Institute of Chemical Technology
US Patent
Korea Research Institute of Chemical Technology
US Patent
Affinity DataIC50: 3nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHO cells after 3 hrs by HTRF cortisol assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.70nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in CHOK1 cells using XL665-labeled cortisol as substrate measured after 24 hrs by HTRF assayMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in CHO-K1 cells using cortisone as substrate after 3 hrs by HTRF assayMore data for this Ligand-Target Pair
TargetTRAF2 and NCK-interacting protein kinase(Homo sapiens (Human))
Korea Research Institute of Chemical Technology
US Patent
Korea Research Institute of Chemical Technology
US Patent
Affinity DataIC50: 4nMAssay Description:The inhibitory properties of compounds were evaluated with TNIK kinase enzyme system and luminescent ADP-GloFigure US11485711-20221101-P00001 Kinase ...More data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in CHO cells after 3 hrs by HTRF cortisol assayMore data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Korea Research Institute of Chemical Technology
US Patent
Korea Research Institute of Chemical Technology
US Patent
Affinity DataIC50: 4.80nMAssay Description:The in vitro inhibitory activities of the novel compounds to human 11β-HSD1 were evaluated in accordance with homogenous time-resolved fluoresce...More data for this Ligand-Target Pair