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Found 46 with Last Name = 'kirkpatrick' and Initial = 'j'
TargetComplement C1s subcomponent(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50233679(CHEMBL399284 | N-[3'-(5-carbamimidoyl-2-methylsulf...)
Affinity DataKi:  14nMAssay Description:Inhibition of Complement C1s subcomponentMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetComplement C1s subcomponent(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50233691(4-(2'-amino-6'-methyl-biphenyl-3-sulfonyl)-5-methy...)
Affinity DataKi:  20nMAssay Description:Inhibition of Complement C1s subcomponentMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetComplement C1s subcomponent(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50233674(6-{3-[3'-(5-carbamimidoyl-2-methylsulfanyl-thiophe...)
Affinity DataKi:  22nMAssay Description:Inhibition of Complement C1s subcomponentMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetComplement C1s subcomponent(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50233686(4-(2'-methyl-biphenyl-3-sulfonyl)-5-methylsulfanyl...)
Affinity DataKi:  30nMAssay Description:Inhibition of Complement C1s subcomponentMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetComplement C1s subcomponent(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50233692(4-[3-(6-methyl-pyridin-2-yl)-benzenesulfonyl]-5-me...)
Affinity DataKi:  40nMAssay Description:Inhibition of Complement C1s subcomponentMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetComplement C1s subcomponent(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50233688(4-(2'-chloro-biphenyl-3-sulfonyl)-5-methylsulfanyl...)
Affinity DataKi:  40nMAssay Description:Inhibition of Complement C1s subcomponentMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetComplement C1s subcomponent(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50233694(5-[3'-(5-carbamimidoyl-2-methylsulfanyl-thiophene-...)
Affinity DataKi:  42nMAssay Description:Inhibition of Complement C1s subcomponentMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetComplement C1s subcomponent(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50233677(4-(2'-hydroxymethyl-6'-methyl-biphenyl-3-sulfonyl)...)
Affinity DataKi:  50nMAssay Description:Inhibition of Complement C1s subcomponentMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetComplement C1s subcomponent(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50233689(5-methylsulfanyl-4-(6'-methyl-2'-{3-[2-(2H-tetrazo...)
Affinity DataKi:  64nMAssay Description:Inhibition of Complement C1s subcomponentMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetComplement C1s subcomponent(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50233680(4-(2'-hydroxymethyl-biphenyl-3-sulfonyl)-5-methyls...)
Affinity DataKi:  120nMAssay Description:Inhibition of Complement C1s subcomponentMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetComplement C1s subcomponent(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50233693(CHEMBL252619 | N-[3'-(5-carbamimidoyl-2-methylsulf...)
Affinity DataKi:  120nMAssay Description:Inhibition of Complement C1s subcomponentMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetComplement C1s subcomponent(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50233681(5-methylsulfanyl-4-(2'-vinyl-biphenyl-3-sulfonyl)-...)
Affinity DataKi:  140nMAssay Description:Inhibition of Complement C1s subcomponentMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetComplement C1s subcomponent(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50233676(3'-(5-carbamimidoyl-2-methylsulfanyl-thiophene-3-s...)
Affinity DataKi:  150nMAssay Description:Inhibition of Complement C1s subcomponentMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetComplement C1s subcomponent(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50233683(4-(3'-hydroxy-biphenyl-3-sulfonyl)-5-methylsulfany...)
Affinity DataKi:  150nMAssay Description:Inhibition of Complement C1s subcomponentMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetComplement C1s subcomponent(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50233678(4-(4'-hydroxy-biphenyl-3-sulfonyl)-5-methylsulfany...)
Affinity DataKi:  190nMAssay Description:Inhibition of Complement C1s subcomponentMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetComplement C1s subcomponent(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50233687(4-(4'-methyl-biphenyl-3-sulfonyl)-5-methylsulfanyl...)
Affinity DataKi:  250nMAssay Description:Inhibition of Complement C1s subcomponentMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetComplement C1s subcomponent(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50233675(4-(biphenyl-3-sulfonyl)-5-methylsulfanyl-thiophene...)
Affinity DataKi:  260nMAssay Description:Inhibition of Complement C1s subcomponentMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetComplement C1s subcomponent(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50233695(4-(4-methoxy-biphenyl-3-sulfonyl)-5-methylsulfanyl...)
Affinity DataKi:  350nMAssay Description:Inhibition of Complement C1s subcomponentMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetComplement C1s subcomponent(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50233690(4-(3-bromo-benzenesulfonyl)-5-methylsulfanyl-thiop...)
Affinity DataKi:  360nMAssay Description:Inhibition of Complement C1s subcomponentMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetComplement C1s subcomponent(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50233685(4-(2'-hydroxy-biphenyl-3-sulfonyl)-5-methylsulfany...)
Affinity DataKi:  460nMAssay Description:Inhibition of Complement C1s subcomponentMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetComplement C1s subcomponent(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50233682(4-(3-methoxy-biphenyl-3-sulfonyl)-5-methylsulfanyl...)
Affinity DataKi:  490nMAssay Description:Inhibition of Complement C1s subcomponentMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetComplement C1s subcomponent(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50233684(4-(2'-methoxy-biphenyl-3-sulfonyl)-5-methylsulfany...)
Affinity DataKi:  610nMAssay Description:Inhibition of Complement C1s subcomponentMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetComplement C1s subcomponent(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50233696(4-(3'-methyl-biphenyl-3-sulfonyl)-5-methylsulfanyl...)
Affinity DataKi:  1.85E+3nMAssay Description:Inhibition of Complement C1s subcomponentMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Johnson And Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50217358(4-(6-amino-5-((methoxyimino)methyl)pyrimidin-4-yl)...)
Affinity DataIC50:  1nMAssay Description:Inhibition of human FLT3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Johnson And Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50217367(4-(6-amino-5-((methoxyimino)methyl)pyrimidin-4-yl)...)
Affinity DataIC50:  3nMAssay Description:Inhibition of human FLT3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Johnson And Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50217357(4-(6-amino-5-((methoxyimino)methyl)pyrimidin-4-yl)...)
Affinity DataIC50:  14nMAssay Description:Inhibition of human FLT3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Johnson And Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50217366(4-(6-amino-5-((methoxyimino)methyl)pyrimidin-4-yl)...)
Affinity DataIC50:  15nMAssay Description:Inhibition of human FLT3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Johnson And Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50217350(4-(6-amino-5-((ethoxyimino)methyl)pyrimidin-4-yl)-...)
Affinity DataIC50:  18nMAssay Description:Inhibition of human FLT3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Johnson And Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50217362(4-(6-amino-5-((methoxyimino)methyl)pyrimidin-4-yl)...)
Affinity DataIC50:  18nMAssay Description:Inhibition of human FLT3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Johnson And Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50217348(4-(6-amino-5-((2-morpholinoethoxyimino)methyl)pyri...)
Affinity DataIC50:  36nMAssay Description:Inhibition of human FLT3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Johnson And Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50217349(4-(6-amino-5-((2-morpholino-2-oxoethoxyimino)methy...)
Affinity DataIC50:  41nMAssay Description:Inhibition of human FLT3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Johnson And Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50217361(4-(6-amino-5-((ethoxyimino)methyl)pyrimidin-4-yl)-...)
Affinity DataIC50:  49nMAssay Description:Inhibition of human FLT3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Johnson And Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50217360(4-(6-amino-5-((methoxyimino)methyl)pyrimidin-4-yl)...)
Affinity DataIC50:  50nMAssay Description:Inhibition of human FLT3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Johnson And Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50217359(4-(6-amino-5-((methoxyimino)methyl)pyrimidin-4-yl)...)
Affinity DataIC50:  50nMAssay Description:Inhibition of human FLT3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Johnson And Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50217352(4-(6-amino-5-((ethoxyimino)methyl)pyrimidin-4-yl)-...)
Affinity DataIC50:  58nMAssay Description:Inhibition of human FLT3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Johnson And Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50217353((E)-4-(6-amino-5-((2-morpholino-2-oxoethoxyimino)m...)
Affinity DataIC50:  62nMAssay Description:Inhibition of human FLT3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Johnson And Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50217347(4-(6-amino-5-((methoxyimino)methyl)pyrimidin-4-yl)...)
Affinity DataIC50:  75nMAssay Description:Inhibition of human FLT3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Johnson And Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50217365(4-(6-amino-5-((methoxyimino)methyl)pyrimidin-4-yl)...)
Affinity DataIC50:  99nMAssay Description:Inhibition of human FLT3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Johnson And Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50217356(4-(6-amino-5-((2-(methylsulfonamido)ethoxyimino)me...)
Affinity DataIC50:  146nMAssay Description:Inhibition of human FLT3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Johnson And Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50217355((E)-4-(6-amino-5-((2-(methylsulfonamido)ethoxyimin...)
Affinity DataIC50:  150nMAssay Description:Inhibition of human FLT3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Johnson And Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50217363((E)-4-(6-amino-5-((2-morpholinoethoxyimino)methyl)...)
Affinity DataIC50:  165nMAssay Description:Inhibition of human FLT3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Johnson And Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50217351(4-(6-amino-5-((3-hydroxypropoxyimino)methyl)pyrimi...)
Affinity DataIC50:  260nMAssay Description:Inhibition of human FLT3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Johnson And Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50217354(4-(6-amino-5-((methoxyimino)methyl)pyrimidin-4-yl)...)
Affinity DataIC50:  340nMAssay Description:Inhibition of human FLT3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Johnson And Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50217364(4-(6-amino-5-((methoxyimino)methyl)pyrimidin-4-yl)...)
Affinity DataIC50:  1.37E+3nMAssay Description:Inhibition of human FLT3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Johnson And Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50217360(4-(6-amino-5-((methoxyimino)methyl)pyrimidin-4-yl)...)
Affinity DataIC50:  1.05E+4nMAssay Description:Inhibition of c-kitMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Johnson And Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50217360(4-(6-amino-5-((methoxyimino)methyl)pyrimidin-4-yl)...)
Affinity DataIC50:  1.07E+4nMAssay Description:Inhibition of PDGFRbetaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed