TargetRAC-alpha serine/threonine-protein kinase [139-480,S378A,S381A,T450D,S473D](Homo sapiens (Human))
Abbott Laboratories
Abbott Laboratories
Affinity DataKi: 0.160nM ΔG°: -55.3kJ/molepH: 7.5 T: 2°CAssay Description:The kinase assay uses His-Akt1 and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidin-coated FLASH plat...More data for this Ligand-Target Pair
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataKi: 0.620nMAssay Description:Binding affinity towards Urokinase-type plasminogen activator (urokinase)More data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Inhibition of PARP1 using [3H]NAD+ by top count scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Inhibition of PARP2 by top count scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Inhibition of PARP1 using [3H]NAD+ by top count scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Inhibition of PARP2 by top count scintillation countingMore data for this Ligand-Target Pair
TargetRAC-alpha serine/threonine-protein kinase [139-480,S378A,S381A,T450D,S473D](Homo sapiens (Human))
Abbott Laboratories
Abbott Laboratories
Affinity DataKi: 1.10nM ΔG°: -50.6kJ/molepH: 7.5 T: 2°CAssay Description:The kinase assay uses His-Akt1 and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidin-coated FLASH plat...More data for this Ligand-Target Pair
Affinity DataKi: 1.5nMAssay Description:Inhibition of PARP2 by top count scintillation countingMore data for this Ligand-Target Pair
TargetRAC-alpha serine/threonine-protein kinase [139-480,S378A,S381A,T450D,S473D](Homo sapiens (Human))
Abbott Laboratories
Abbott Laboratories
Affinity DataKi: 2nM ΔG°: -49.2kJ/molepH: 7.5 T: 2°CAssay Description:The kinase assay uses His-Akt1 and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidin-coated FLASH plat...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PLK3(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataKi: 2nMAssay Description:Inhibition of recombinant PLK3 after 1 hr by scintillation counter analysis in presence of gamma-[33P]ATPMore data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Inhibition of PARP1 using [3H]NAD+ by top count scintillation countingMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PLK2(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataKi: 2nMAssay Description:Inhibition of recombinant PLK2 after 1 hr by scintillation counter analysis in presence of gamma-[33P]ATPMore data for this Ligand-Target Pair
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataKi: 2nMAssay Description:Binding affinity towards Urokinase-type plasminogen activator (urokinase)More data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Inhibition of PARP1 using [3H]NAD+ by top count scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Inhibition of PARP1 using [3H]NAD+ by top count scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Inhibition of PARP1 using [3H]NAD+ by top count scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Inhibition of PARP1 using [3H]NAD+ by top count scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Inhibition of PARP1 using [3H]NAD+ by top count scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Inhibition of PARP2 by top count scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Inhibition of PARP2 by top count scintillation countingMore data for this Ligand-Target Pair
TargetRAC-alpha serine/threonine-protein kinase [139-480,S378A,S381A,T450D,S473D](Homo sapiens (Human))
Abbott Laboratories
Abbott Laboratories
Affinity DataKi: 2.10nM ΔG°: -49.0kJ/molepH: 7.5 T: 2°CAssay Description:The kinase assay uses His-Akt1 and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidin-coated FLASH plat...More data for this Ligand-Target Pair
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataKi: 2.10nMAssay Description:Binding affinity towards Urokinase-type plasminogen activator (urokinase)More data for this Ligand-Target Pair
Affinity DataKi: 2.5nM ΔG°: -48.6kJ/molepH: 7.5 T: 2°CAssay Description:Assays were conducted in 384-well v-bottom polypropylene plates. Test compound was mixed with Pim and biotinylated peptide substrate, followed by imm...More data for this Ligand-Target Pair
Affinity DataKi: 3nMAssay Description:PARP assays utilizing SPA bead-based detection were carried out in 96-well plates. After reaction was terminated, the reaction mixtures were transfer...More data for this Ligand-Target Pair
Affinity DataKi: 3nMAssay Description:Inhibition of PARP2 by top count scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 3nMAssay Description:PARP assays utilizing SPA bead-based detection were carried out in 96-well plates. After reaction was terminated, the reaction mixtures were transfer...More data for this Ligand-Target Pair
Affinity DataKi: 3nM ΔG°: -48.2kJ/molepH: 8.0 T: 2°CAssay Description:PARP assays utilizing SPA bead-based detection were carried out in 96-well plates. After reaction was terminated, the reaction mixtures were transfer...More data for this Ligand-Target Pair
Affinity DataKi: 3nMAssay Description:Inhibition of PARP2 by top count scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 3nMAssay Description:Inhibition of PARP1 using [3H]NAD+ by top count scintillation countingMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataKi: 3nMAssay Description:Inhibition of recombinant GST-tagged PLK1 using biotin-ahx-AKMETTFYDDALNASFLPSEKKK-amide as substrate after 30 mins by scintillation counting analysi...More data for this Ligand-Target Pair
Affinity DataKi: 3nMAssay Description:Inhibition of PARP1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 3nMAssay Description:Inhibition of PARP1 using [3H]NAD+ by top count scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 3nMAssay Description:Inhibition of PARP1 using [3H]NAD+ by top count scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 3nMAssay Description:Binding affinity against trypsinMore data for this Ligand-Target Pair
Affinity DataKi: 3nMAssay Description:Inhibition of PARP2 by top count scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 3nMAssay Description:Inhibition of PARP1 using [3H]NAD+ by top count scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 3nMAssay Description:Inhibition of PARP1 using [3H]NAD+ by top count scintillation countingMore data for this Ligand-Target Pair
TargetRAC-alpha serine/threonine-protein kinase [139-480,S378A,S381A,T450D,S473D](Homo sapiens (Human))
Abbott Laboratories
Abbott Laboratories
Affinity DataKi: 3.20nM ΔG°: -48.0kJ/molepH: 7.5 T: 2°CAssay Description:The kinase assay uses His-Akt1 and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidin-coated FLASH plat...More data for this Ligand-Target Pair
Affinity DataKi: 3.5nMAssay Description:Binding affinity against trypsinMore data for this Ligand-Target Pair
TargetRAC-alpha serine/threonine-protein kinase [139-480,S378A,S381A,T450D,S473D](Homo sapiens (Human))
Abbott Laboratories
Abbott Laboratories
Affinity DataKi: 3.5nM ΔG°: -47.8kJ/molepH: 7.5 T: 2°CAssay Description:The kinase assay uses His-Akt1 and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidin-coated FLASH plat...More data for this Ligand-Target Pair
Affinity DataKi: 4nM ΔG°: -47.5kJ/molepH: 8.0 T: 2°CAssay Description:PARP assays utilizing SPA bead-based detection were carried out in 96-well plates. After reaction was terminated, the reaction mixtures were transfer...More data for this Ligand-Target Pair
Affinity DataKi: 4nMAssay Description:PARP assays utilizing SPA bead-based detection were carried out in 96-well plates. After reaction was terminated, the reaction mixtures were transfer...More data for this Ligand-Target Pair
Affinity DataKi: 4nM ΔG°: -47.5kJ/molepH: 8.0 T: 2°CAssay Description:PARP assays utilizing SPA bead-based detection were carried out in 96-well plates. After reaction was terminated, the reaction mixtures were transfer...More data for this Ligand-Target Pair
Affinity DataKi: 4nM ΔG°: -47.5kJ/molepH: 8.0 T: 2°CAssay Description:PARP assays utilizing SPA bead-based detection were carried out in 96-well plates. After reaction was terminated, the reaction mixtures were transfer...More data for this Ligand-Target Pair
Affinity DataKi: 4nM ΔG°: -47.5kJ/molepH: 8.0 T: 2°CAssay Description:PARP assays utilizing SPA bead-based detection were carried out in 96-well plates. After reaction was terminated, the reaction mixtures were transfer...More data for this Ligand-Target Pair
Affinity DataKi: 4nM ΔG°: -47.5kJ/molepH: 8.0 T: 2°CAssay Description:PARP assays utilizing SPA bead-based detection were carried out in 96-well plates. After reaction was terminated, the reaction mixtures were transfer...More data for this Ligand-Target Pair
Affinity DataKi: 4nMAssay Description:Inhibition of PARP1 using [3H]NAD+ by top count scintillation countingMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataKi: 4nMAssay Description:Inhibition of recombinant GST-tagged PLK1 using biotin-ahx-AKMETTFYDDALNASFLPSEKKK-amide as substrate after 30 mins by scintillation counting analysi...More data for this Ligand-Target Pair
Affinity DataKi: 4nMAssay Description:Inhibition of PARP1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 4nMAssay Description:Inhibition of PARP1 using [3H]NAD+ by top count scintillation countingMore data for this Ligand-Target Pair