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Found 583 with Last Name = 'klutchko' and Initial = 'sr'
LigandPNGBDBM50030815(CHEMBL404594)
Affinity DataIC50:  0.100nMAssay Description:Binding affinity for rat brain Angiotensin II receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Parke-Davis Pharmaceutical Research Division Of Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50006848(CHEMBL88091 | N-[2-(2-Amino-thiazol-4-yl)-1-(1-cyc...)
Affinity DataIC50:  0.160nMAssay Description:In vitro inhibition of monkey renin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM4566(4-anilinoquinazoline deriv. 1 | CHEMBL91867 | N-{4...)
Affinity DataIC50:  0.200nMAssay Description:Inhibition of erbB1 fusion protein expressed in baculovirus by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Parke-Davis Pharmaceutical Research Division Of Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50006850(CHEMBL313063 | N-[1-(1-Cyclohexylmethyl-2,3-dihydr...)
Affinity DataIC50:  0.200nMAssay Description:In vitro inhibition of monkey renin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Parke-Davis Pharmaceutical Research Division Of Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50006858(CHEMBL315380 | N-[1-(1-Cyclohexylmethyl-2,3-dihydr...)
Affinity DataIC50:  0.230nMAssay Description:In vitro inhibition of monkey renin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Parke-Davis Pharmaceutical Research Division Of Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50006854(CHEMBL88069 | N-[2-(2-Amino-thiazol-4-yl)-1-(1-cyc...)
Affinity DataIC50:  0.270nMAssay Description:In vitro inhibition of monkey renin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Parke-Davis Pharmaceutical Research Division Of Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50006853(CHEMBL315211 | N-(1-Cyclohexylmethyl-2,3-dihydroxy...)
Affinity DataIC50:  0.280nMAssay Description:In vitro inhibition of monkey renin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50182693(CHEMBL203644 | N-[4-[(3-chloro-4-fluorophenyl)amin...)
Affinity DataIC50:  0.300nMAssay Description:Inhibition of erbB1 fusion protein expressed in baculovirus by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Parke-Davis Pharmaceutical Research Division Of Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50006845(CHEMBL316208 | N-[2-(2-Amino-thiazol-4-yl)-1-(1-cy...)
Affinity DataIC50:  0.350nMAssay Description:In vitro inhibition of monkey renin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50030815(CHEMBL404594)
Affinity DataIC50:  0.350nMAssay Description:Binding affinity against Angiotensin II receptor, from rat adrenal glandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Parke-Davis Pharmaceutical Research Division Of Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50006844((S)-N-[(S)-2-(2-Amino-thiazol-4-yl)-1-((1S,2R,3S)-...)
Affinity DataIC50:  0.360nMAssay Description:In vitro inhibition of monkey renin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Parke-Davis Pharmaceutical Research Division Of Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50006844((S)-N-[(S)-2-(2-Amino-thiazol-4-yl)-1-((1S,2R,3S)-...)
Affinity DataIC50:  0.370nMAssay Description:Compound was evaluated for inhibition of plasma renin activity in monkeyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Parke-Davis Pharmaceutical Research Division Of Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50006851(CHEMBL263531 | N-[1-(1-Cyclohexylmethyl-2,3-dihydr...)
Affinity DataIC50:  0.480nMAssay Description:In vitro inhibition of monkey renin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Parke-Davis Pharmaceutical Research Division Of Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50006856(4-{3-(2-Amino-thiazol-4-yl)-2-[2-(morpholine-4-sul...)
Affinity DataIC50:  0.5nMAssay Description:In vitro inhibition of monkey renin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50182697(CHEMBL203599 | N-[4-[(3-chloro-4-fluorophenyl)amin...)
Affinity DataIC50:  0.5nMAssay Description:Inhibition of erbB1 fusion protein expressed in baculovirus by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-4(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50182693(CHEMBL203644 | N-[4-[(3-chloro-4-fluorophenyl)amin...)
Affinity DataIC50:  0.5nMAssay Description:Inhibition of erbB4 fusion protein expressed in baculovirus by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50182688(CHEMBL204638 | N-[4-[(3-bromo-4-fluorophenyl)amino...)
Affinity DataIC50:  0.5nMAssay Description:Inhibition of HER stimulated human erbB autophosphorylation in MDA-MB-453 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50182684(CHEMBL437890 | N-[4-[(3-bromo-4-fluorophenyl)amino...)
Affinity DataIC50:  0.5nMAssay Description:Inhibition of erbB2 fusion protein expressed in baculovirus by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Parke-Davis Pharmaceutical Research Division Of Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50006846(4-{3-(2-Amino-thiazol-4-yl)-2-[2-(morpholine-4-sul...)
Affinity DataIC50:  0.540nMAssay Description:In vitro inhibition of monkey renin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Parke-Davis Pharmaceutical Research Division Of Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50006844((S)-N-[(S)-2-(2-Amino-thiazol-4-yl)-1-((1S,2R,3S)-...)
Affinity DataIC50:  0.570nMAssay Description:Compound was evaluated for inhibition of plasma renin activity in humanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Parke-Davis Pharmaceutical Research Division Of Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50006843(CHEMBL314066 | N-[(2-Amino-thiazol-4-yl)-(1-cycloh...)
Affinity DataIC50:  0.581nMAssay Description:In vitro inhibition of monkey renin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Parke-Davis Pharmaceutical Research Division Of Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50006849(4-{3-(2-Amino-thiazol-4-yl)-2-[2-(morpholine-4-sul...)
Affinity DataIC50:  0.590nMAssay Description:In vitro inhibition of monkey renin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM5446(CHEMBL553 | ERLOTINIB HYDROCHLORIDE | Erlotinib | ...)
Affinity DataIC50:  0.600nMAssay Description:Inhibition of erbB1 fusion protein expressed in baculovirus by ELISAMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50182689(CHEMBL378144 | N-[4-[(3-bromophenyl)amino]pyrido[3...)
Affinity DataIC50:  0.600nMAssay Description:Inhibition of erbB1 fusion protein expressed in baculovirus by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50182688(CHEMBL204638 | N-[4-[(3-bromo-4-fluorophenyl)amino...)
Affinity DataIC50:  0.700nMAssay Description:Inhibition of erbB2 fusion protein expressed in baculovirus by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50182697(CHEMBL203599 | N-[4-[(3-chloro-4-fluorophenyl)amin...)
Affinity DataIC50:  0.700nMAssay Description:Inhibition of erbB2 fusion protein expressed in baculovirus by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Parke-Davis Pharmaceutical Research Division Of Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50006202(3-Amino-N-[1-[1-(1-cyclohexylmethyl-2,3-dihydroxy-...)
Affinity DataIC50:  0.760nMAssay Description:In vitro inhibition of monkey renin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50182682(CHEMBL203661 | N-[4-[(3-chloro-4-fluorophenyl)amin...)
Affinity DataIC50:  0.800nMAssay Description:Inhibition of erbB2 fusion protein expressed in baculovirus by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50182697(CHEMBL203599 | N-[4-[(3-chloro-4-fluorophenyl)amin...)
Affinity DataIC50:  0.800nMAssay Description:Inhibition of ligand stimulated erbB2 autophosphorylation in T24 NIH cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-4(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50182684(CHEMBL437890 | N-[4-[(3-bromo-4-fluorophenyl)amino...)
Affinity DataIC50:  0.800nMAssay Description:Inhibition of erbB4 fusion protein expressed in baculovirus by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Parke-Davis Pharmaceutical Research Division Of Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM17941((2S,4S,5S)-5-[(2S)-2-[(2S)-2-benzyl-3-[(2-methylpr...)
Affinity DataIC50:  0.830nMAssay Description:In vitro inhibition of monkey renin.More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50182678(CHEMBL205059 | N-[4-[(3-chloro-4-fluorophenyl)amin...)
Affinity DataIC50:  0.900nMAssay Description:Inhibition of erbB1 fusion protein expressed in baculovirus by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Parke-Davis Pharmaceutical Research Division Of Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50006860(CHEMBL85672 | {1-[2-(2-Amino-thiazol-4-yl)-1-(1-cy...)
Affinity DataIC50:  0.910nMAssay Description:In vitro inhibition of monkey renin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50182697(CHEMBL203599 | N-[4-[(3-chloro-4-fluorophenyl)amin...)
Affinity DataIC50:  1nMAssay Description:Inhibition of HER stimulated human erbB autophosphorylation in MDA-MB-453 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-4(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50182682(CHEMBL203661 | N-[4-[(3-chloro-4-fluorophenyl)amin...)
Affinity DataIC50:  1nMAssay Description:Inhibition of erbB4 fusion protein expressed in baculovirus by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-4(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50182688(CHEMBL204638 | N-[4-[(3-bromo-4-fluorophenyl)amino...)
Affinity DataIC50:  1nMAssay Description:Inhibition of erbB4 fusion protein expressed in baculovirus by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50182684(CHEMBL437890 | N-[4-[(3-bromo-4-fluorophenyl)amino...)
Affinity DataIC50:  1.10nMAssay Description:Inhibition of erbB1 fusion protein expressed in baculovirus by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50182693(CHEMBL203644 | N-[4-[(3-chloro-4-fluorophenyl)amin...)
Affinity DataIC50:  1.10nMAssay Description:Inhibition of erbB2 fusion protein expressed in baculovirus by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-4(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50182697(CHEMBL203599 | N-[4-[(3-chloro-4-fluorophenyl)amin...)
Affinity DataIC50:  1.20nMAssay Description:Inhibition of erbB4 fusion protein expressed in baculovirus by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50182682(CHEMBL203661 | N-[4-[(3-chloro-4-fluorophenyl)amin...)
Affinity DataIC50:  1.30nMAssay Description:Inhibition of erbB1 fusion protein expressed in baculovirus by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50228195(Angiotensin Ii | CHEBI:2719)
Affinity DataIC50:  1.30nMAssay Description:Binding affinity against Angiotensin II receptor, from rat adrenal glandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50182690(CHEMBL202411 | N-[4-[(3-Chloro-4-fluorophenyl)amin...)
Affinity DataIC50:  1.40nMAssay Description:Inhibition of erbB1 fusion protein expressed in baculovirus by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50182688(CHEMBL204638 | N-[4-[(3-bromo-4-fluorophenyl)amino...)
Affinity DataIC50:  1.5nMAssay Description:Inhibition of erbB1 fusion protein expressed in baculovirus by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50228894(CHEMBL312754)
Affinity DataIC50:  1.60nMAssay Description:Binding affinity against Angiotensin II receptor, from rat adrenal glandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50182695(CHEMBL202360 | N-[4-[(3-bromophenyl)amino]-6-quina...)
Affinity DataIC50:  1.60nMAssay Description:Inhibition of erbB1 fusion protein expressed in baculovirus by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50182687(CHEMBL203645 | N-[4-[(3-chloro-4-fluorophenyl)amin...)
Affinity DataIC50:  1.70nMAssay Description:Inhibition of erbB1 fusion protein expressed in baculovirus by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50182698(CHEMBL204085 | N-[4-[(3-chloro-4-fluorophenyl)amin...)
Affinity DataIC50:  1.70nMAssay Description:Inhibition of erbB1 fusion protein expressed in baculovirus by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-4(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50182695(CHEMBL202360 | N-[4-[(3-bromophenyl)amino]-6-quina...)
Affinity DataIC50:  1.70nMAssay Description:Inhibition of erbB4 fusion protein expressed in baculovirus by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM4779(CHEMBL31965 | CHEMBL545315 | CI-1033 | Canertinib ...)
Affinity DataIC50:  1.70nMAssay Description:Inhibition of EGF stimulated human erbB1 autophosphorylation in NIH3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-4(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50182678(CHEMBL205059 | N-[4-[(3-chloro-4-fluorophenyl)amin...)
Affinity DataIC50:  1.80nMAssay Description:Inhibition of erbB4 fusion protein expressed in baculovirus by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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