Found 943 with Last Name = 'knust' and Initial = 'h' TargetGamma-aminobutyric acid receptor subunit alpha-5(Homo sapiens (Human))
Roche Palo Alto
US Patent
Roche Palo Alto
US Patent
Affinity DataKi: 0.100nM ΔG°: -53.1kJ/molepH: 7.5 T: 2°CAssay Description:Radioligand binding assays were carried out in a volume of 200 mL (96-well plates) which contained 100 mL of cell memebranes, [3H]flumazenil at a con...More data for this Ligand-Target Pair
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Homo sapiens (Human))
F. Hoffmann-La Roche
Curated by ChEMBL
F. Hoffmann-La Roche
Curated by ChEMBL
Affinity DataKi: 0.200nMAssay Description:Binding affinity to GABAA alpha-5-beta-3-gamma-2 receptorMore data for this Ligand-Target Pair
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Homo sapiens (Human))
F. Hoffmann-La Roche
Curated by ChEMBL
F. Hoffmann-La Roche
Curated by ChEMBL
Affinity DataKi: 0.200nMAssay Description:Binding affinity to GABAA alpha-5-beta-3-gamma-2 receptorMore data for this Ligand-Target Pair
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Homo sapiens (Human))
F. Hoffmann-La Roche
Curated by ChEMBL
F. Hoffmann-La Roche
Curated by ChEMBL
Affinity DataKi: 0.200nMAssay Description:Binding affinity to GABAA alpha-5-beta-3-gamma-2 receptorMore data for this Ligand-Target Pair
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Homo sapiens (Human))
F. Hoffmann-La Roche
Curated by ChEMBL
F. Hoffmann-La Roche
Curated by ChEMBL
Affinity DataKi: 0.200nMAssay Description:Binding affinity to GABAA alpha-5-beta-3-gamma-2 receptorMore data for this Ligand-Target Pair
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Homo sapiens (Human))
F. Hoffmann-La Roche
Curated by ChEMBL
F. Hoffmann-La Roche
Curated by ChEMBL
Affinity DataKi: 0.200nMAssay Description:Displacement of [3H]Flumazenil from cloned human GABAalpha5beta3gamma2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Homo sapiens (Human))
F. Hoffmann-La Roche
Curated by ChEMBL
F. Hoffmann-La Roche
Curated by ChEMBL
Affinity DataKi: 0.200nMAssay Description:Displacement of [3H]Flumazenil from human GABAalpha5beta3gamma2 receptor expressed in insect SF9 cellsMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-5(Homo sapiens (Human))
Roche Palo Alto
US Patent
Roche Palo Alto
US Patent
Affinity DataKi: 0.200nM ΔG°: -51.5kJ/molepH: 7.5 T: 2°CAssay Description:Radioligand binding assays were carried out in a volume of 200 mL (96-well plates) which contained 100 mL of cell memebranes, [3H]flumazenil at a con...More data for this Ligand-Target Pair
Affinity DataKi: 0.200nMAssay Description:Electrophysiological experiments were performed on days 3 to 5 after the micro-injection of mRNA. During the experiment the oocytes were constantly s...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-5(Homo sapiens (Human))
Roche Palo Alto
US Patent
Roche Palo Alto
US Patent
Affinity DataKi: 0.300nM ΔG°: -50.5kJ/molepH: 7.5 T: 2°CAssay Description:Radioligand binding assays were carried out in a volume of 200 mL (96-well plates) which contained 100 mL of cell memebranes, [3H]flumazenil at a con...More data for this Ligand-Target Pair
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Homo sapiens (Human))
F. Hoffmann-La Roche
Curated by ChEMBL
F. Hoffmann-La Roche
Curated by ChEMBL
Affinity DataKi: 0.300nMAssay Description:Binding affinity to GABAA alpha-5-beta-3-gamma-2 receptorMore data for this Ligand-Target Pair
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Homo sapiens (Human))
F. Hoffmann-La Roche
Curated by ChEMBL
F. Hoffmann-La Roche
Curated by ChEMBL
Affinity DataKi: 0.300nMAssay Description:Displacement of [3H]Flumazenil from human GABAalpha5beta3gamma2 receptor expressed in insect SF9 cellsMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-5(Homo sapiens (Human))
Roche Palo Alto
US Patent
Roche Palo Alto
US Patent
Affinity DataKi: 0.300nM ΔG°: -50.5kJ/molepH: 7.5 T: 2°CAssay Description:Radioligand binding assays were carried out in a volume of 200 mL (96-well plates) which contained 100 mL of cell memebranes, [3H]flumazenil at a con...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-5(Homo sapiens (Human))
Roche Palo Alto
US Patent
Roche Palo Alto
US Patent
Affinity DataKi: 0.300nM ΔG°: -50.5kJ/molepH: 7.5 T: 2°CAssay Description:Radioligand binding assays were carried out in a volume of 200 mL (96-well plates) which contained 100 mL of cell memebranes, [3H]flumazenil at a con...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-5(Homo sapiens (Human))
Roche Palo Alto
US Patent
Roche Palo Alto
US Patent
Affinity DataKi: 0.300nM ΔG°: -50.5kJ/molepH: 7.5 T: 2°CAssay Description:Radioligand binding assays were carried out in a volume of 200 mL (96-well plates) which contained 100 mL of cell memebranes, [3H]flumazenil at a con...More data for this Ligand-Target Pair
Affinity DataKi: 0.300nM ΔG°: -50.5kJ/molepH: 7.4 T: 2°CAssay Description:hNK3 receptor binding experiment were performed using [3H]SR142801 (Catalog No. TRK1035, specific activity: 74.0 Ci/mmol, Amersham, GE Healthcare UK ...More data for this Ligand-Target Pair
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Homo sapiens (Human))
F. Hoffmann-La Roche
Curated by ChEMBL
F. Hoffmann-La Roche
Curated by ChEMBL
Affinity DataKi: 0.300nMAssay Description:Displacement of [3H]Flumazenil from cloned human GABAalpha5beta3gamma2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-5(Homo sapiens (Human))
Roche Palo Alto
US Patent
Roche Palo Alto
US Patent
Affinity DataKi: 0.300nM ΔG°: -50.5kJ/molepH: 7.5 T: 2°CAssay Description:Radioligand binding assays were carried out in a volume of 200 mL (96-well plates) which contained 100 mL of cell memebranes, [3H]flumazenil at a con...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-5(Homo sapiens (Human))
Roche Palo Alto
US Patent
Roche Palo Alto
US Patent
Affinity DataKi: 0.300nM ΔG°: -50.5kJ/molepH: 7.5 T: 2°CAssay Description:Radioligand binding assays were carried out in a volume of 200 mL (96-well plates) which contained 100 mL of cell memebranes, [3H]flumazenil at a con...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-5(Homo sapiens (Human))
Roche Palo Alto
US Patent
Roche Palo Alto
US Patent
Affinity DataKi: 0.400nM ΔG°: -49.9kJ/molepH: 7.5 T: 2°CAssay Description:Radioligand binding assays were carried out in a volume of 200 mL (96-well plates) which contained 100 mL of cell memebranes, [3H]flumazenil at a con...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-5(Homo sapiens (Human))
Roche Palo Alto
US Patent
Roche Palo Alto
US Patent
Affinity DataKi: 0.400nM ΔG°: -49.9kJ/molepH: 7.5 T: 2°CAssay Description:Radioligand binding assays were carried out in a volume of 200 mL (96-well plates) which contained 100 mL of cell memebranes, [3H]flumazenil at a con...More data for this Ligand-Target Pair
Affinity DataKi: 0.400nMAssay Description:Electrophysiological experiments were performed on days 3 to 5 after the micro-injection of mRNA. During the experiment the oocytes were constantly s...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-5(Homo sapiens (Human))
Roche Palo Alto
US Patent
Roche Palo Alto
US Patent
Affinity DataKi: 0.400nM ΔG°: -49.9kJ/molepH: 7.5 T: 2°CAssay Description:Radioligand binding assays were carried out in a volume of 200 mL (96-well plates) which contained 100 mL of cell memebranes, [3H]flumazenil at a con...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-5(Homo sapiens (Human))
Roche Palo Alto
US Patent
Roche Palo Alto
US Patent
Affinity DataKi: 0.400nM ΔG°: -49.9kJ/molepH: 7.5 T: 2°CAssay Description:Radioligand binding assays were carried out in a volume of 200 mL (96-well plates) which contained 100 mL of cell memebranes, [3H]flumazenil at a con...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1(Homo sapiens (Human))
Hoffmann-La Roche
US Patent
Hoffmann-La Roche
US Patent
Affinity DataKi: 0.400nMAssay Description:Electrophysiological experiments were performed on days 3 to 5 after the micro-injection of mRNA. During the experiment the oocytes were constantly s...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-5(Homo sapiens (Human))
Roche Palo Alto
US Patent
Roche Palo Alto
US Patent
Affinity DataKi: 0.400nM ΔG°: -49.9kJ/molepH: 7.5 T: 2°CAssay Description:Radioligand binding assays were carried out in a volume of 200 mL (96-well plates) which contained 100 mL of cell memebranes, [3H]flumazenil at a con...More data for this Ligand-Target Pair
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Homo sapiens (Human))
F. Hoffmann-La Roche
Curated by ChEMBL
F. Hoffmann-La Roche
Curated by ChEMBL
Affinity DataKi: 0.5nMAssay Description:Binding affinity to GABAA alpha-5-beta-3-gamma-2 receptorMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-5(Homo sapiens (Human))
Roche Palo Alto
US Patent
Roche Palo Alto
US Patent
Affinity DataKi: 0.5nM ΔG°: -49.3kJ/molepH: 7.5 T: 2°CAssay Description:Radioligand binding assays were carried out in a volume of 200 mL (96-well plates) which contained 100 mL of cell memebranes, [3H]flumazenil at a con...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-5(Homo sapiens (Human))
Roche Palo Alto
US Patent
Roche Palo Alto
US Patent
Affinity DataKi: 0.5nM ΔG°: -49.3kJ/molepH: 7.5 T: 2°CAssay Description:Radioligand binding assays were carried out in a volume of 200 mL (96-well plates) which contained 100 mL of cell memebranes, [3H]flumazenil at a con...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-5(Homo sapiens (Human))
Roche Palo Alto
US Patent
Roche Palo Alto
US Patent
Affinity DataKi: 0.5nM ΔG°: -49.3kJ/molepH: 7.5 T: 2°CAssay Description:Radioligand binding assays were carried out in a volume of 200 mL (96-well plates) which contained 100 mL of cell memebranes, [3H]flumazenil at a con...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-5(Homo sapiens (Human))
Roche Palo Alto
US Patent
Roche Palo Alto
US Patent
Affinity DataKi: 0.5nM ΔG°: -49.3kJ/molepH: 7.5 T: 2°CAssay Description:Radioligand binding assays were carried out in a volume of 200 mL (96-well plates) which contained 100 mL of cell memebranes, [3H]flumazenil at a con...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-5(Homo sapiens (Human))
Roche Palo Alto
US Patent
Roche Palo Alto
US Patent
Affinity DataKi: 0.5nM ΔG°: -49.3kJ/molepH: 7.5 T: 2°CAssay Description:Radioligand binding assays were carried out in a volume of 200 mL (96-well plates) which contained 100 mL of cell memebranes, [3H]flumazenil at a con...More data for this Ligand-Target Pair
Affinity DataKi: 0.5nM ΔG°: -49.3kJ/molepH: 7.4 T: 2°CAssay Description:hNK3 receptor binding experiment were performed using [3H]SR142801 (Catalog No. TRK1035, specific activity: 74.0 Ci/mmol, Amersham, GE Healthcare UK ...More data for this Ligand-Target Pair
Affinity DataKi: 0.5nM ΔG°: -49.3kJ/molepH: 7.4 T: 2°CAssay Description:hNK3 receptor binding experiment were performed using [3H]SR142801 (Catalog No. TRK1035, specific activity: 74.0 Ci/mmol, Amersham, GE Healthcare UK ...More data for this Ligand-Target Pair
Affinity DataKi: 0.5nM ΔG°: -49.3kJ/molepH: 7.4 T: 2°CAssay Description:hNK3 receptor binding experiment were performed using [3H]SR142801 (Catalog No. TRK1035, specific activity: 74.0 Ci/mmol, Amersham, GE Healthcare UK ...More data for this Ligand-Target Pair
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Homo sapiens (Human))
F. Hoffmann-La Roche
Curated by ChEMBL
F. Hoffmann-La Roche
Curated by ChEMBL
Affinity DataKi: 0.5nMAssay Description:Binding affinity to GABAA alpha-5-beta-3-gamma-2 receptorMore data for this Ligand-Target Pair
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Homo sapiens (Human))
F. Hoffmann-La Roche
Curated by ChEMBL
F. Hoffmann-La Roche
Curated by ChEMBL
Affinity DataKi: 0.600nMAssay Description:Binding affinity to GABAA alpha-5-beta-3-gamma-2 receptorMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-5(Homo sapiens (Human))
Roche Palo Alto
US Patent
Roche Palo Alto
US Patent
Affinity DataKi: 0.600nM ΔG°: -48.9kJ/molepH: 7.5 T: 2°CAssay Description:Radioligand binding assays were carried out in a volume of 200 mL (96-well plates) which contained 100 mL of cell memebranes, [3H]flumazenil at a con...More data for this Ligand-Target Pair
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Homo sapiens (Human))
F. Hoffmann-La Roche
Curated by ChEMBL
F. Hoffmann-La Roche
Curated by ChEMBL
Affinity DataKi: 0.600nMAssay Description:Binding affinity to GABAA alpha-5-beta-3-gamma-2 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.600nMAssay Description:Displacement of [3H]substance P from human neurokinin NK1 receptor expressed in CHO cellMore data for this Ligand-Target Pair
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Homo sapiens (Human))
F. Hoffmann-La Roche
Curated by ChEMBL
F. Hoffmann-La Roche
Curated by ChEMBL
Affinity DataKi: 0.600nMAssay Description:Displacement of [3H]flumazenil from GABAAalpha5beta3gamma2 receptorMore data for this Ligand-Target Pair
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Homo sapiens (Human))
F. Hoffmann-La Roche
Curated by ChEMBL
F. Hoffmann-La Roche
Curated by ChEMBL
Affinity DataKi: 0.600nMAssay Description:Displacement of [3H]flumazenil from GABAAalpha5beta3gamma2 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.600nM ΔG°: -48.9kJ/molepH: 7.4 T: 2°CAssay Description:hNK3 receptor binding experiment were performed using [3H]SR142801 (Catalog No. TRK1035, specific activity: 74.0 Ci/mmol, Amersham, GE Healthcare UK ...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-5(Homo sapiens (Human))
Roche Palo Alto
US Patent
Roche Palo Alto
US Patent
Affinity DataKi: 0.600nM ΔG°: -48.9kJ/molepH: 7.5 T: 2°CAssay Description:Radioligand binding assays were carried out in a volume of 200 mL (96-well plates) which contained 100 mL of cell memebranes, [3H]flumazenil at a con...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-5(Homo sapiens (Human))
Roche Palo Alto
US Patent
Roche Palo Alto
US Patent
Affinity DataKi: 0.600nM ΔG°: -48.9kJ/molepH: 7.5 T: 2°CAssay Description:Radioligand binding assays were carried out in a volume of 200 mL (96-well plates) which contained 100 mL of cell memebranes, [3H]flumazenil at a con...More data for this Ligand-Target Pair
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Homo sapiens (Human))
F. Hoffmann-La Roche
Curated by ChEMBL
F. Hoffmann-La Roche
Curated by ChEMBL
Affinity DataKi: 0.600nMAssay Description:Binding affinity to GABAA alpha-5-beta-3-gamma-2 receptorMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-5(Homo sapiens (Human))
Roche Palo Alto
US Patent
Roche Palo Alto
US Patent
Affinity DataKi: 0.600nM ΔG°: -48.9kJ/molepH: 7.5 T: 2°CAssay Description:Radioligand binding assays were carried out in a volume of 200 mL (96-well plates) which contained 100 mL of cell memebranes, [3H]flumazenil at a con...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-5(Homo sapiens (Human))
Roche Palo Alto
US Patent
Roche Palo Alto
US Patent
Affinity DataKi: 0.600nM ΔG°: -48.9kJ/molepH: 7.5 T: 2°CAssay Description:Radioligand binding assays were carried out in a volume of 200 mL (96-well plates) which contained 100 mL of cell memebranes, [3H]flumazenil at a con...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-5(Homo sapiens (Human))
Roche Palo Alto
US Patent
Roche Palo Alto
US Patent
Affinity DataKi: 0.600nM ΔG°: -48.9kJ/molepH: 7.5 T: 2°CAssay Description:Radioligand binding assays were carried out in a volume of 200 mL (96-well plates) which contained 100 mL of cell memebranes, [3H]flumazenil at a con...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-5(Homo sapiens (Human))
Roche Palo Alto
US Patent
Roche Palo Alto
US Patent
Affinity DataKi: 0.600nM ΔG°: -48.9kJ/molepH: 7.5 T: 2°CAssay Description:Radioligand binding assays were carried out in a volume of 200 mL (96-well plates) which contained 100 mL of cell memebranes, [3H]flumazenil at a con...More data for this Ligand-Target Pair
