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Found 353 with Last Name = 'konkar' and Initial = 'a'
TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
University Of Tennessee-Memphis

Curated by ChEMBL
LigandPNGBDBM50470923(CHEMBL122757)
Affinity DataKi:  0.302nMAssay Description:Binding affinity for human Beta-2 adrenergic receptor expressed in CHO cells by radioligand competition binding assays using [125I]iodocyanopindolol ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetB1 bradykinin receptor(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM140558(US8912221, 31)
Affinity DataKi:  0.600nMpH: 7.4Assay Description:For binding, Bradykinin-1 receptor antagonist compounds were added in various concentrations in 50 mM Tris pH 7.4, 5 mM MgCl2 together with 6 nM Kall...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetB1 bradykinin receptor(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM140539(US8912221, 12)
Affinity DataKi:  0.800nMpH: 7.4Assay Description:For binding, Bradykinin-1 receptor antagonist compounds were added in various concentrations in 50 mM Tris pH 7.4, 5 mM MgCl2 together with 6 nM Kall...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetB1 bradykinin receptor(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM140552(US8912221, 25)
Affinity DataKi:  1nMpH: 7.4Assay Description:For binding, Bradykinin-1 receptor antagonist compounds were added in various concentrations in 50 mM Tris pH 7.4, 5 mM MgCl2 together with 6 nM Kall...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetB1 bradykinin receptor(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM140540(US8912221, 13)
Affinity DataKi:  1nMpH: 7.4Assay Description:For binding, Bradykinin-1 receptor antagonist compounds were added in various concentrations in 50 mM Tris pH 7.4, 5 mM MgCl2 together with 6 nM Kall...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetB1 bradykinin receptor(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM140550(US8912221, 23)
Affinity DataKi:  1nMpH: 7.4Assay Description:For binding, Bradykinin-1 receptor antagonist compounds were added in various concentrations in 50 mM Tris pH 7.4, 5 mM MgCl2 together with 6 nM Kall...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetB1 bradykinin receptor(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM140542(US8912221, 15)
Affinity DataKi:  1.10nMpH: 7.4Assay Description:For binding, Bradykinin-1 receptor antagonist compounds were added in various concentrations in 50 mM Tris pH 7.4, 5 mM MgCl2 together with 6 nM Kall...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetB1 bradykinin receptor(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM140567(US8912221, 40)
Affinity DataKi:  1.10nMpH: 7.4Assay Description:For binding, Bradykinin-1 receptor antagonist compounds were added in various concentrations in 50 mM Tris pH 7.4, 5 mM MgCl2 together with 6 nM Kall...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetB1 bradykinin receptor(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM140532(US8912221, 5)
Affinity DataKi:  1.10nMpH: 7.4Assay Description:For binding, Bradykinin-1 receptor antagonist compounds were added in various concentrations in 50 mM Tris pH 7.4, 5 mM MgCl2 together with 6 nM Kall...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetB1 bradykinin receptor(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM140571(US8912221, 44)
Affinity DataKi:  1.10nMpH: 7.4Assay Description:For binding, Bradykinin-1 receptor antagonist compounds were added in various concentrations in 50 mM Tris pH 7.4, 5 mM MgCl2 together with 6 nM Kall...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCannabinoid receptor 1(Homo sapiens (Human))
Bayer Healthcare

Curated by ChEMBL
LigandPNGBDBM21278(5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl...)
Affinity DataKi:  1.10nMAssay Description:Displacement of [3H]CP559440 from human CB1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetB1 bradykinin receptor(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM140563(US8912221, 36)
Affinity DataKi:  1.20nMpH: 7.4Assay Description:For binding, Bradykinin-1 receptor antagonist compounds were added in various concentrations in 50 mM Tris pH 7.4, 5 mM MgCl2 together with 6 nM Kall...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetB1 bradykinin receptor(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM140551(US8912221, 24)
Affinity DataKi:  1.20nMpH: 7.4Assay Description:For binding, Bradykinin-1 receptor antagonist compounds were added in various concentrations in 50 mM Tris pH 7.4, 5 mM MgCl2 together with 6 nM Kall...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetB1 bradykinin receptor(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM140557(US8912221, 30)
Affinity DataKi:  1.30nMpH: 7.4Assay Description:For binding, Bradykinin-1 receptor antagonist compounds were added in various concentrations in 50 mM Tris pH 7.4, 5 mM MgCl2 together with 6 nM Kall...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetB1 bradykinin receptor(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM140570(US8912221, 43)
Affinity DataKi:  1.40nMpH: 7.4Assay Description:For binding, Bradykinin-1 receptor antagonist compounds were added in various concentrations in 50 mM Tris pH 7.4, 5 mM MgCl2 together with 6 nM Kall...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetB1 bradykinin receptor(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM140541(US8912221, 14)
Affinity DataKi:  1.40nMpH: 7.4Assay Description:For binding, Bradykinin-1 receptor antagonist compounds were added in various concentrations in 50 mM Tris pH 7.4, 5 mM MgCl2 together with 6 nM Kall...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetB1 bradykinin receptor(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM140555(US8912221, 28)
Affinity DataKi:  1.40nMpH: 7.4Assay Description:For binding, Bradykinin-1 receptor antagonist compounds were added in various concentrations in 50 mM Tris pH 7.4, 5 mM MgCl2 together with 6 nM Kall...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
University Of Tennessee-Memphis

Curated by ChEMBL
LigandPNGBDBM50470918(CHEMBL123596)
Affinity DataKi:  1.5nMAssay Description:Binding affinity for human Beta-2 adrenergic receptor expressed in CHO cells by radioligand competition binding assays using [125I]iodocyanopindolol ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
University Of Tennessee-Memphis

Curated by ChEMBL
LigandPNGBDBM50470917(CHEMBL120278)
Affinity DataKi:  1.5nMAssay Description:Binding affinity for human Beta-2 adrenergic receptor expressed in CHO cells by radioligand competition binding assays using [125I]iodocyanopindolol ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetB1 bradykinin receptor(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM140547(US8912221, 20)
Affinity DataKi:  1.60nMpH: 7.4Assay Description:For binding, Bradykinin-1 receptor antagonist compounds were added in various concentrations in 50 mM Tris pH 7.4, 5 mM MgCl2 together with 6 nM Kall...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetB1 bradykinin receptor(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM140543(US8912221, 16)
Affinity DataKi:  1.60nMpH: 7.4Assay Description:For binding, Bradykinin-1 receptor antagonist compounds were added in various concentrations in 50 mM Tris pH 7.4, 5 mM MgCl2 together with 6 nM Kall...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetB1 bradykinin receptor(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM140534(US8912221, 7)
Affinity DataKi:  1.60nMpH: 7.4Assay Description:For binding, Bradykinin-1 receptor antagonist compounds were added in various concentrations in 50 mM Tris pH 7.4, 5 mM MgCl2 together with 6 nM Kall...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetB1 bradykinin receptor(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM140549(US8912221, 22)
Affinity DataKi:  1.70nMpH: 7.4Assay Description:For binding, Bradykinin-1 receptor antagonist compounds were added in various concentrations in 50 mM Tris pH 7.4, 5 mM MgCl2 together with 6 nM Kall...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCannabinoid receptor 1(Homo sapiens (Human))
Bayer Healthcare

Curated by ChEMBL
LigandPNGBDBM50208974(CHEMBL390543 | N-cyclohexyl-2-(2,4-dichlorophenyl)...)
Affinity DataKi:  1.90nMAssay Description:Displacement of [3H]CP559440 from human CB1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
University Of Tennessee-Memphis

Curated by ChEMBL
LigandPNGBDBM82487(TMQ, 3',5'-Diiodo)
Affinity DataKi:  2nMAssay Description:Binding affinity for human Beta-2 adrenergic receptor expressed in CHO cells by radioligand competition binding assays using [125I]iodocyanopindolol ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
University Of Tennessee-Memphis

Curated by ChEMBL
LigandPNGBDBM82487(TMQ, 3',5'-Diiodo)
Affinity DataKi:  2nMAssay Description:Binding Affinity against human beta-2 adrenergic receptor expressed in Chinese hamster ovary(CHO) cells was measured by using [125I]ICYP radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
University Of Tennessee-Memphis

Curated by ChEMBL
LigandPNGBDBM50470916(CHEMBL121704)
Affinity DataKi:  2nMAssay Description:Binding affinity for human Beta-2 adrenergic receptor expressed in CHO cells by radioligand competition binding assays using [125I]iodocyanopindolol ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Bayer Healthcare

Curated by ChEMBL
LigandPNGBDBM50198507(2-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-3-methyl...)
Affinity DataKi:  2.20nMAssay Description:Displacement of [3H]CP-55940 from human CB1 receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetB1 bradykinin receptor(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM140561(US8912221, 34)
Affinity DataKi:  2.20nMpH: 7.4Assay Description:For binding, Bradykinin-1 receptor antagonist compounds were added in various concentrations in 50 mM Tris pH 7.4, 5 mM MgCl2 together with 6 nM Kall...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCannabinoid receptor 1(Homo sapiens (Human))
Bayer Healthcare

Curated by ChEMBL
LigandPNGBDBM50208948(2-(2-chlorophenyl)-1-(4-chlorophenyl)-N-cyclohexyl...)
Affinity DataKi:  2.20nMAssay Description:Displacement of [3H]CP559440 from human CB1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetB1 bradykinin receptor(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM140559(US8912221, 32)
Affinity DataKi:  2.30nMpH: 7.4Assay Description:For binding, Bradykinin-1 receptor antagonist compounds were added in various concentrations in 50 mM Tris pH 7.4, 5 mM MgCl2 together with 6 nM Kall...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetB1 bradykinin receptor(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM140530(US8912221, 3)
Affinity DataKi:  2.40nMpH: 7.4Assay Description:For binding, Bradykinin-1 receptor antagonist compounds were added in various concentrations in 50 mM Tris pH 7.4, 5 mM MgCl2 together with 6 nM Kall...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetB1 bradykinin receptor(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM140531(US8912221, 4)
Affinity DataKi:  2.5nMpH: 7.4Assay Description:For binding, Bradykinin-1 receptor antagonist compounds were added in various concentrations in 50 mM Tris pH 7.4, 5 mM MgCl2 together with 6 nM Kall...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetB1 bradykinin receptor(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM140538(US8912221, 11)
Affinity DataKi:  2.60nMpH: 7.4Assay Description:For binding, Bradykinin-1 receptor antagonist compounds were added in various concentrations in 50 mM Tris pH 7.4, 5 mM MgCl2 together with 6 nM Kall...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetKininogen-1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM107177(US8592426, 26)
Affinity DataKi:  2.60nMAssay Description:Binding assay using Bradykinin-1 receptor.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetB1 bradykinin receptor(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM140528(US8912221, 1)
Affinity DataKi:  2.60nMpH: 7.4Assay Description:For binding, Bradykinin-1 receptor antagonist compounds were added in various concentrations in 50 mM Tris pH 7.4, 5 mM MgCl2 together with 6 nM Kall...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCannabinoid receptor 1(Homo sapiens (Human))
Bayer Healthcare

Curated by ChEMBL
LigandPNGBDBM50198532(1-(2-chlorophenyl)-2-(4-chlorophenyl)-5-cyclohexyl...)
Affinity DataKi:  2.80nMAssay Description:Displacement of [3H]CP-55940 from human CB1 receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKininogen-1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM107189(US8592426, 38)
Affinity DataKi:  3nMAssay Description:Binding assay using Bradykinin-1 receptor.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetB1 bradykinin receptor(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM140545(US8912221, 18)
Affinity DataKi:  3nMpH: 7.4Assay Description:For binding, Bradykinin-1 receptor antagonist compounds were added in various concentrations in 50 mM Tris pH 7.4, 5 mM MgCl2 together with 6 nM Kall...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetKininogen-1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM107176(US8592426, 25)
Affinity DataKi:  3.10nMAssay Description:Binding assay using Bradykinin-1 receptor.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetB1 bradykinin receptor(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM140562(US8912221, 35)
Affinity DataKi:  3.30nMpH: 7.4Assay Description:For binding, Bradykinin-1 receptor antagonist compounds were added in various concentrations in 50 mM Tris pH 7.4, 5 mM MgCl2 together with 6 nM Kall...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetKininogen-1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM107209(US8592426, 59)
Affinity DataKi:  3.5nMAssay Description:Binding assay using Bradykinin-1 receptor.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCannabinoid receptor 1(Homo sapiens (Human))
Bayer Healthcare

Curated by ChEMBL
LigandPNGBDBM50198519(1-(2-chlorophenyl)-2-(4-chlorophenyl)-3-methyl-5-(...)
Affinity DataKi:  3.5nMAssay Description:Displacement of [3H]CP-55940 from human CB1 receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetB1 bradykinin receptor(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM140564(US8912221, 37)
Affinity DataKi:  3.5nMpH: 7.4Assay Description:For binding, Bradykinin-1 receptor antagonist compounds were added in various concentrations in 50 mM Tris pH 7.4, 5 mM MgCl2 together with 6 nM Kall...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetKininogen-1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM107178(US8592426, 27)
Affinity DataKi:  3.60nMAssay Description:Binding assay using Bradykinin-1 receptor.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetKininogen-1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM107203(US8592426, 53)
Affinity DataKi:  3.60nMAssay Description:Binding assay using Bradykinin-1 receptor.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCannabinoid receptor 1(Homo sapiens (Human))
Bayer Healthcare

Curated by ChEMBL
LigandPNGBDBM50208975(1-(4-bromophenyl)-2-(2-chlorophenyl)-5-ethyl-N-((1...)
Affinity DataKi:  3.70nMAssay Description:Displacement of [3H]CP559440 from human CB1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Bayer Healthcare

Curated by ChEMBL
LigandPNGBDBM50140237(1-(4-Chloro-phenyl)-2-(2,4-dichloro-phenyl)-1H-imi...)
Affinity DataKi:  3.90nMAssay Description:Displacement of [3H]CP559440 from human CB1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKininogen-1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM107181(US8592426, 30)
Affinity DataKi:  3.90nMAssay Description:Binding assay using Bradykinin-1 receptor.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetKininogen-1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM107190(US8592426, 116 | US8592426, 117 | US8592426, 39/40...)
Affinity DataKi:  4nMAssay Description:Binding assay using Bradykinin-1 receptor.More data for this Ligand-Target Pair
In DepthDetails US Patent
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