TargetMu-type opioid receptor(Rattus norvegicus (rat))
National Institute On Drug Abuse and The National Institute On Alcohol Abuse
Curated by ChEMBL
National Institute On Drug Abuse and The National Institute On Alcohol Abuse
Curated by ChEMBL
Affinity DataKi: 0.0730nMAssay Description:Non-competitive inhibition of recombinant human MAO-B expressed in baculovirus infected BTI insect cells using varying levels of tyramine as substrat...More data for this Ligand-Target Pair
TargetMu-type opioid receptor(Rattus norvegicus (rat))
National Institute On Drug Abuse and The National Institute On Alcohol Abuse
Curated by ChEMBL
National Institute On Drug Abuse and The National Institute On Alcohol Abuse
Curated by ChEMBL
Affinity DataKi: 0.265nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in rat brain after 60 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Rattus norvegicus (rat))
National Institute On Drug Abuse and The National Institute On Alcohol Abuse
Curated by ChEMBL
National Institute On Drug Abuse and The National Institute On Alcohol Abuse
Curated by ChEMBL
Affinity DataKi: 0.741nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in rat brain after 60 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Drew University
Curated by ChEMBL
Drew University
Curated by ChEMBL
Affinity DataKi: 0.900nMAssay Description:Displacement of [125I]RTI-55 from human Norepinephrine transporter expressed in HEK cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1.05nMAssay Description:Displacement of [125I]- RTI-55 from Dopamine transporter expressed in HEK cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1.70nMAssay Description:Inhibition of [125I]- RTI -55 binding at the Dopamine transporter sites on HEK-hDAT cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1.70nMAssay Description:Ability to displace [125I]- RTI-55 binding at the Dopamine transporter site on HEK cells expressing cDNA for the human transporter (hDAT)More data for this Ligand-Target Pair
TargetMu-type opioid receptor(Rattus norvegicus (rat))
National Institute On Drug Abuse and The National Institute On Alcohol Abuse
Curated by ChEMBL
National Institute On Drug Abuse and The National Institute On Alcohol Abuse
Curated by ChEMBL
Affinity DataKi: 2nMAssay Description:Displacement of [3H]DADLE from delta opioid receptor in rat brain after 60 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 2.01nMAssay Description:Inhibition of [125I]- RTI -55 binding at the Dopamine transporter sites on HEK-hDAT cellsMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Rattus norvegicus (rat))
National Institute On Drug Abuse and The National Institute On Alcohol Abuse
Curated by ChEMBL
National Institute On Drug Abuse and The National Institute On Alcohol Abuse
Curated by ChEMBL
Affinity DataKi: 2.30nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in rat brain after 60 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 2.30nMAssay Description:Inhibition of [125I]- RTI -55 binding at the Serotonin transporter sites on HEK-hSERT cellsMore data for this Ligand-Target Pair
Affinity DataKi: 2.55nMAssay Description:Displacement of [125I]- RTI-55 from Dopamine transporter expressed in HEK cellsMore data for this Ligand-Target Pair
Affinity DataKi: 2.83nMAssay Description:Inhibition of [125I]- RTI -55 binding at the Dopamine transporter sites on HEK-hDAT cellsMore data for this Ligand-Target Pair
Affinity DataKi: 2.90nMAssay Description:Displacement of [125I]- RTI-55 from Dopamine transporter expressed in HEK cellsMore data for this Ligand-Target Pair
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
National Institute On Drug Abuse and The National Institute On Alcohol Abuse
Curated by ChEMBL
National Institute On Drug Abuse and The National Institute On Alcohol Abuse
Curated by ChEMBL
Affinity DataKi: 3.5nMAssay Description:Displacement of [3H]DADLE from delta opioid receptor in rat brain after 60 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Rattus norvegicus (rat))
National Institute On Drug Abuse and The National Institute On Alcohol Abuse
Curated by ChEMBL
National Institute On Drug Abuse and The National Institute On Alcohol Abuse
Curated by ChEMBL
Affinity DataKi: 4nMAssay Description:Displacement of [3H]U-69,593 from kappa opioid receptor in rat brain after 60 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Institute On Drug Abuse-Intramural Research Program
Curated by ChEMBL
National Institute On Drug Abuse-Intramural Research Program
Curated by ChEMBL
Affinity DataKi: 4.10nMAssay Description:Displacement of [3H]WIN-35428 from dopamine transporter of rat brain membraneMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Institute On Drug Abuse-Intramural Research Program
Curated by ChEMBL
National Institute On Drug Abuse-Intramural Research Program
Curated by ChEMBL
Affinity DataKi: 4.11nMAssay Description:Displacement of [3H]WIN-from DAT in rat brain membraneMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Institute On Drug Abuse-Intramural Research Program
Curated by ChEMBL
National Institute On Drug Abuse-Intramural Research Program
Curated by ChEMBL
Affinity DataKi: 4.61nMAssay Description:Displacement of [3H]WIN-from DAT in rat brain membraneMore data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Drew University
Curated by ChEMBL
Drew University
Curated by ChEMBL
Affinity DataKi: 5.20nMAssay Description:Inhibition of [125I]- RTI -55 binding at the Norepinephrin transpoter sites on HEK-hNET cellsMore data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Drew University
Curated by ChEMBL
Drew University
Curated by ChEMBL
Affinity DataKi: 5.30nMAssay Description:Inhibition of [125I]- RTI -55 binding at the Norepinephrin transpoter sites on HEK-hNET cellsMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Institute On Drug Abuse-Intramural Research Program
Curated by ChEMBL
National Institute On Drug Abuse-Intramural Research Program
Curated by ChEMBL
Affinity DataKi: 5.35nMAssay Description:Displacement of [3H]WIN-from DAT in rat brain membraneMore data for this Ligand-Target Pair
Affinity DataKi: 5.5nMAssay Description:Inhibition of [125I]- RTI -55 binding at the Serotonin transporter sites on HEK-hSERT cellsMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Institute On Drug Abuse-Intramural Research Program
Curated by ChEMBL
National Institute On Drug Abuse-Intramural Research Program
Curated by ChEMBL
Affinity DataKi: 5.59nMAssay Description:Displacement of [3H]WIN-from DAT in rat brain membraneMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Institute On Drug Abuse-Intramural Research Program
Curated by ChEMBL
National Institute On Drug Abuse-Intramural Research Program
Curated by ChEMBL
Affinity DataKi: 5.80nMAssay Description:Displacement of [3H]WIN-35428 from dopamine transporter of rat brain membraneMore data for this Ligand-Target Pair
Affinity DataKi: 6nMAssay Description:Displacement of [125I]- RTI-55 from Dopamine transporter expressed in HEK cellsMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Institute On Drug Abuse-Intramural Research Program
Curated by ChEMBL
National Institute On Drug Abuse-Intramural Research Program
Curated by ChEMBL
Affinity DataKi: 6.22nMAssay Description:Displacement of [3H]WIN-from DAT in rat brain membraneMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Institute On Drug Abuse-Intramural Research Program
Curated by ChEMBL
National Institute On Drug Abuse-Intramural Research Program
Curated by ChEMBL
Affinity DataKi: 6.30nMAssay Description:Displacement of [3H]WIN-35428 from dopamine transporter of rat brain membraneMore data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Drew University
Curated by ChEMBL
Drew University
Curated by ChEMBL
Affinity DataKi: 6.80nMAssay Description:Displacement of [125I]RTI-55 from human Norepinephrine transporter expressed in HEK cellsMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
National Institute On Drug Abuse-Intramural Research Program
Curated by ChEMBL
National Institute On Drug Abuse-Intramural Research Program
Curated by ChEMBL
Affinity DataKi: 7.81nMAssay Description:Displacement of [3H]pirenzepine from Muscarinic receptor M1More data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Institute On Drug Abuse-Intramural Research Program
Curated by ChEMBL
National Institute On Drug Abuse-Intramural Research Program
Curated by ChEMBL
Affinity DataKi: 8.45nMAssay Description:Displacement of [3H]WIN-from DAT in rat brain membraneMore data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Drew University
Curated by ChEMBL
Drew University
Curated by ChEMBL
Affinity DataKi: 8.80nMAssay Description:Ability to displace [125I]- RTI-55 binding at the Norepinephrine transporter site on HEK cells expressing cDNA for the human transporter (hNET)More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
National Institute On Drug Abuse-Intramural Research Program
Curated by ChEMBL
National Institute On Drug Abuse-Intramural Research Program
Curated by ChEMBL
Affinity DataKi: 9.30nMAssay Description:Displacement of [3H]pirenzepine from Muscarinic receptor M1More data for this Ligand-Target Pair
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
National Institute On Drug Abuse and The National Institute On Alcohol Abuse
Curated by ChEMBL
National Institute On Drug Abuse and The National Institute On Alcohol Abuse
Curated by ChEMBL
Affinity DataKi: 9.80nMAssay Description:Displacement of [3H]DADLE from delta opioid receptor in rat brain after 60 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 10.3nMAssay Description:Displacement of [125I]- RTI-55 from Dopamine transporter expressed in HEK cellsMore data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Drew University
Curated by ChEMBL
Drew University
Curated by ChEMBL
Affinity DataKi: 11nMAssay Description:Inhibition of [125I]- RTI -55 binding at the Norepinephrin transpoter sites on HEK-hNET cellsMore data for this Ligand-Target Pair
Affinity DataKi: 11nMAssay Description:Inhibition of [125I]- RTI -55 binding at the Serotonin transporter sites on HEK-hSERT cellsMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Institute On Drug Abuse-Intramural Research Program
Curated by ChEMBL
National Institute On Drug Abuse-Intramural Research Program
Curated by ChEMBL
Affinity DataKi: 11.3nMAssay Description:Displacement of [3H]WIN-from DAT in rat brain membraneMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
National Institute On Drug Abuse-Intramural Research Program
Curated by ChEMBL
National Institute On Drug Abuse-Intramural Research Program
Curated by ChEMBL
Affinity DataKi: 11.6nMAssay Description:Displacement of [3H]pirenzepine from Muscarinic receptor M1More data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Institute On Drug Abuse-Intramural Research Program
Curated by ChEMBL
National Institute On Drug Abuse-Intramural Research Program
Curated by ChEMBL
Affinity DataKi: 11.7nMAssay Description:Displacement of [3H]WIN-from DAT in rat brain membraneMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Rattus norvegicus (rat))
National Institute On Drug Abuse and The National Institute On Alcohol Abuse
Curated by ChEMBL
National Institute On Drug Abuse and The National Institute On Alcohol Abuse
Curated by ChEMBL
Affinity DataKi: 12nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in rat brain after 60 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M1(RAT)
National Institute On Drug Abuse-Intramural Research Program
Curated by ChEMBL
National Institute On Drug Abuse-Intramural Research Program
Curated by ChEMBL
Affinity DataKi: 12nMAssay Description:Displacement of [3H]pirenzepine from muscarinic acetylcholine receptor M1 of rat brain membraneMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Institute On Drug Abuse-Intramural Research Program
Curated by ChEMBL
National Institute On Drug Abuse-Intramural Research Program
Curated by ChEMBL
Affinity DataKi: 12.5nMAssay Description:Displacement of [3H]WIN-from DAT in rat brain membraneMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
National Institute On Drug Abuse-Intramural Research Program
Curated by ChEMBL
National Institute On Drug Abuse-Intramural Research Program
Curated by ChEMBL
Affinity DataKi: 17.8nMAssay Description:Displacement of [3H]pirenzepine from Muscarinic receptor M1More data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Drew University
Curated by ChEMBL
Drew University
Curated by ChEMBL
Affinity DataKi: 18nMAssay Description:Displacement of [125I]RTI-55 from human Norepinephrine transporter expressed in HEK cellsMore data for this Ligand-Target Pair
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
National Institute On Drug Abuse and The National Institute On Alcohol Abuse
Curated by ChEMBL
National Institute On Drug Abuse and The National Institute On Alcohol Abuse
Curated by ChEMBL
Affinity DataKi: 18nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in rat brain after 60 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Drew University
Curated by ChEMBL
Drew University
Curated by ChEMBL
Affinity DataKi: 18nMAssay Description:Displacement of [125I]RTI-55 from human Norepinephrine transporter expressed in HEK cellsMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Institute On Drug Abuse-Intramural Research Program
Curated by ChEMBL
National Institute On Drug Abuse-Intramural Research Program
Curated by ChEMBL
Affinity DataKi: 18nMAssay Description:Ability to displace [3H]- WIN 35,428 from dopamine transporter on rat striatal membrane.More data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Drew University
Curated by ChEMBL
Drew University
Curated by ChEMBL
Affinity DataKi: 18nMAssay Description:Inhibition of [125I]- RTI -55 binding at the Norepinephrin transpoter sites on HEK-hNET cellsMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
National Institute On Drug Abuse-Intramural Research Program
Curated by ChEMBL
National Institute On Drug Abuse-Intramural Research Program
Curated by ChEMBL
Affinity DataKi: 18.6nMAssay Description:Displacement of [3H]pirenzepine from Muscarinic receptor M1More data for this Ligand-Target Pair