Compile Data Set for Download or QSAR
maximum 50k data
Found 1431 with Last Name = 'kramer' and Initial = 'j'
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Cayman Chemical

US Patent
LigandPNGBDBM190273(US9180116, 21C)
Affinity DataKi:  0.0820nM IC50:  0.220nMpH: 6.0Assay Description:Assay Volume and Format:200 μl in 96-well plateCell membrane homogenates (20 μg protein) are incubated for 120 min at 22° C. with 0.5 nM [3...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Cayman Chemical

US Patent
LigandPNGBDBM190282(US9180116, 33C)
Affinity DataKi:  0.100nM IC50:  0.280nMpH: 6.0Assay Description:Assay Volume and Format:200 μl in 96-well plateCell membrane homogenates (20 μg protein) are incubated for 120 min at 22° C. with 0.5 nM [3...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Cayman Chemical

US Patent
LigandPNGBDBM35847((15S)-prostaglandin E2 | (5Z,11alpha,13E,15S)-11,1...)
Affinity DataKi:  0.110nMAssay Description:Displacement of [3H]PGE2 from human recombinant EP4 receptor expressed in HEK293 cell membranes after 120 mins by liquid scintillation counting metho...More data for this Ligand-Target Pair
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Cayman Chemical

US Patent
LigandPNGBDBM190272(US9180116, 12D)
Affinity DataKi:  0.120nM IC50:  0.320nMpH: 6.0Assay Description:Assay Volume and Format:200 μl in 96-well plateCell membrane homogenates (20 μg protein) are incubated for 120 min at 22° C. with 0.5 nM [3...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Cayman Chemical

US Patent
LigandPNGBDBM50101822((Z)-7-[(1R,2R,3R)-3-Hydroxy-2-((E)-(R)-3-hydroxy-o...)
Affinity DataKi:  0.140nM IC50:  0.380nMpH: 6.0Assay Description:Assay Volume and Format:200 μl in 96-well plateCell membrane homogenates (20 μg protein) are incubated for 120 min at 22° C. with 0.5 nM [3...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Cayman Chemical

US Patent
LigandPNGBDBM190270(US9180116, 9C)
Affinity DataKi:  0.200nMAssay Description:Displacement of [3H]PGE2 from human recombinant EP4 receptor expressed in HEK293 cell membranes after 120 mins by liquid scintillation counting metho...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Cayman Chemical

US Patent
LigandPNGBDBM190270(US9180116, 9C)
Affinity DataKi:  0.210nM IC50:  0.570nMpH: 6.0Assay Description:Assay Volume and Format:200 μl in 96-well plateCell membrane homogenates (20 μg protein) are incubated for 120 min at 22° C. with 0.5 nM [3...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Cayman Chemical

US Patent
LigandPNGBDBM190275(US9180116, 28C | US9180116, 28H)
Affinity DataKi:  0.280nM IC50:  0.740nMpH: 6.0Assay Description:Assay Volume and Format:200 μl in 96-well plateCell membrane homogenates (20 μg protein) are incubated for 120 min at 22° C. with 0.5 nM [3...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Cayman Chemical

US Patent
LigandPNGBDBM190268(US9180116, 2C)
Affinity DataKi:  0.378nMAssay Description:Displacement of [3H]PGE2 from human recombinant EP4 receptor expressed in HEK293 cell membranes after 120 mins by liquid scintillation counting metho...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Cayman Chemical

US Patent
LigandPNGBDBM50101858(4-(2-((1R,2R,3R)-3-hydroxy-2-((S,E)-3-hydroxy-4-(3...)
Affinity DataKi:  0.396nMAssay Description:Displacement of [3H]PGE2 from human recombinant EP4 receptor expressed in HEK293 cell membranes after 120 mins by liquid scintillation counting metho...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Cayman Chemical

US Patent
LigandPNGBDBM190267(US9180116, 1F)
Affinity DataKi:  0.440nM IC50:  1.20nMpH: 6.0Assay Description:Assay Volume and Format:200 μl in 96-well plateCell membrane homogenates (20 μg protein) are incubated for 120 min at 22° C. with 0.5 nM [3...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Cayman Chemical

US Patent
LigandPNGBDBM190268(US9180116, 2C)
Affinity DataKi:  0.490nM IC50:  1.30nMpH: 6.0Assay Description:Assay Volume and Format:200 μl in 96-well plateCell membrane homogenates (20 μg protein) are incubated for 120 min at 22° C. with 0.5 nM [3...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Cayman Chemical

US Patent
LigandPNGBDBM190269(US9180116, 6D)
Affinity DataKi:  0.890nM IC50:  2.40nMpH: 6.0Assay Description:Assay Volume and Format:200 μl in 96-well plateCell membrane homogenates (20 μg protein) are incubated for 120 min at 22° C. with 0.5 nM [3...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Cayman Chemical

Curated by ChEMBL
LigandPNGBDBM35847((15S)-prostaglandin E2 | (5Z,11alpha,13E,15S)-11,1...)
Affinity DataKi:  1nMAssay Description:Displacement of [3H]PGE2 from human recombinant EP2 receptor expressed in HEK293 cell membranes after 120 mins by liquid scintillation counting metho...More data for this Ligand-Target Pair
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Cayman Chemical

US Patent
LigandPNGBDBM190274(US9180116, 24D)
Affinity DataKi:  1.20nM IC50:  3.30nMpH: 6.0Assay Description:Assay Volume and Format:200 μl in 96-well plateCell membrane homogenates (20 μg protein) are incubated for 120 min at 22° C. with 0.5 nM [3...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Cayman Chemical

US Patent
LigandPNGBDBM50142481(7-[(R)-2-((E)-(S)-3-Hydroxy-oct-1-enyl)-5-oxo-pyrr...)
Affinity DataKi:  1.60nMAssay Description:Displacement of [3H]PGE2 from human recombinant EP4 receptor expressed in HEK293 cell membranes after 120 mins by liquid scintillation counting metho...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Cayman Chemical

US Patent
LigandPNGBDBM190271(US9180116, 10C)
Affinity DataKi:  1.80nM IC50:  4.90nMpH: 6.0Assay Description:Assay Volume and Format:200 μl in 96-well plateCell membrane homogenates (20 μg protein) are incubated for 120 min at 22° C. with 0.5 nM [3...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Cayman Chemical

Curated by ChEMBL
LigandPNGBDBM35847((15S)-prostaglandin E2 | (5Z,11alpha,13E,15S)-11,1...)
Affinity DataKi:  2.20nMAssay Description:Displacement of [3H]PGE2 from human recombinant EP3 receptor expressed in HEK293 cell membranes after 120 mins by liquid scintillation counting metho...More data for this Ligand-Target Pair
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Cayman Chemical

US Patent
LigandPNGBDBM50521600(CHEMBL4558749)
Affinity DataKi:  2.30nMAssay Description:Displacement of [3H]PGE2 from human recombinant EP4 receptor expressed in HEK293 cell membranes after 120 mins by liquid scintillation counting metho...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50116538(3-{[3-(4-Benzyl-phenoxy)-propyl]-methyl-amino}-pro...)
Affinity DataKi:  3nMAssay Description:Non-competitive inhibition of human C-terminal his6-tagged/N-terminal T7 gene leader sequence-tagged LTA4H using varying levels of L-arginine-7-amino...More data for this Ligand-Target Pair
TargetAdenosine receptor A1(Rattus norvegicus (rat))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50368197(CHEMBL2235597 | CHEMBL603935)
Affinity DataKi:  3.60nMAssay Description:Binding affinity towards adenosine A1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Rattus norvegicus (rat))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50368192(CHEMBL2235605 | CHEMBL604358)
Affinity DataKi:  5nMAssay Description:Binding affinity towards adenosine A1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Rattus norvegicus (rat))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50368179(CHEMBL2236001 | CHEMBL604974)
Affinity DataKi:  5.20nMAssay Description:Binding affinity towards adenosine A1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Rattus norvegicus (rat))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50368183(CHEMBL604141)
Affinity DataKi:  8.40nMAssay Description:Binding affinity towards adenosine A1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a/A2b(Rattus norvegicus)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50085667((2R,3S,4R,5R)-2-Hydroxymethyl-5-{6-[(naphthalen-1-...)
Affinity DataKi:  9.40nMAssay Description:Binding affinity towards adenosine A2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Homo sapiens (Human))
Vanderbilt University Department Of Chemistry

Curated by ChEMBL
LigandPNGBDBM50010477(CHEMBL1233799)
Affinity DataKi:  11nMAssay Description:Inhibition of human ACE N-terminal domain using Cbz-Phe-His-Leu-OH substrateMore data for this Ligand-Target Pair
TargetAngiotensin-converting enzyme(Homo sapiens (Human))
Vanderbilt University Department Of Chemistry

Curated by ChEMBL
LigandPNGBDBM50010479(CHEMBL3264010)
Affinity DataKi:  12nMAssay Description:Inhibition of human ACE N-terminal domain using Cbz-Phe-His-Leu-OH substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Rattus norvegicus (rat))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50453036(CHEMBL2092768)
Affinity DataKi:  12.1nMAssay Description:Binding affinity towards adenosine A1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Rattus norvegicus (rat))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50368190(CHEMBL2235595 | CHEMBL604142)
Affinity DataKi:  14nMAssay Description:Binding affinity towards adenosine A1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Rattus norvegicus (rat))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50368180(CHEMBL2235589 | CHEMBL604764)
Affinity DataKi:  17nMAssay Description:Binding affinity towards adenosine A1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Rattus norvegicus (rat))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50368178(CHEMBL2234029 | CHEMBL604763)
Affinity DataKi:  18nMAssay Description:Binding affinity towards adenosine A1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Rattus norvegicus (rat))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50368211(CHEMBL2236011 | CHEMBL604145)
Affinity DataKi:  20nMAssay Description:Binding affinity towards adenosine A1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Homo sapiens (Human))
Vanderbilt University Department Of Chemistry

Curated by ChEMBL
LigandPNGBDBM50010478(CHEMBL3264009)
Affinity DataKi:  21nMAssay Description:Inhibition of human ACE N-terminal domain using Cbz-Phe-His-Leu-OH substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Rattus norvegicus (rat))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50368215(CHEMBL2235600 | CHEMBL604558)
Affinity DataKi:  22nMAssay Description:Binding affinity towards adenosine A1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Rattus norvegicus (rat))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50229184(CHEMBL2236003)
Affinity DataKi:  23nMAssay Description:Binding affinity towards adenosine A1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Rattus norvegicus (rat))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50368189(CHEMBL2235604 | CHEMBL603926)
Affinity DataKi:  24nMAssay Description:Binding affinity towards adenosine A1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Rattus norvegicus (rat))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50085667((2R,3S,4R,5R)-2-Hydroxymethyl-5-{6-[(naphthalen-1-...)
Affinity DataKi:  24nMAssay Description:Binding affinity towards adenosine A1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Rattus norvegicus (rat))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50368186(CHEMBL2236012 | CHEMBL604148)
Affinity DataKi:  24nMAssay Description:Binding affinity towards adenosine A1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Rattus norvegicus (rat))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50368212(CHEMBL2235590 | CHEMBL604147)
Affinity DataKi:  25nMAssay Description:Binding affinity towards adenosine A1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Rattus norvegicus (rat))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50368217(CHEMBL2235608 | CHEMBL604976)
Affinity DataKi:  28nMAssay Description:Binding affinity towards adenosine A1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Rattus norvegicus (rat))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50368222(CHEMBL2235609 | CHEMBL604767)
Affinity DataKi:  28nMAssay Description:Binding affinity towards adenosine A1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Rattus norvegicus (rat))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50368204(CHEMBL2235596 | CHEMBL603397)
Affinity DataKi:  32nMAssay Description:Binding affinity towards adenosine A1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Rattus norvegicus (rat))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50368207(CHEMBL605165)
Affinity DataKi:  32nMAssay Description:Binding affinity towards adenosine A1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Rattus norvegicus (rat))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50368218(CHEMBL2235607 | CHEMBL603403)
Affinity DataKi:  33nMAssay Description:Binding affinity towards adenosine A1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Homo sapiens (Human))
Vanderbilt University Department Of Chemistry

Curated by ChEMBL
LigandPNGBDBM50010478(CHEMBL3264009)
Affinity DataKi:  33nMAssay Description:Inhibition of human ACE C-terminal domain using Cbz-Phe-His-Leu-OH substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Rattus norvegicus (rat))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50368219(CHEMBL3350060 | CHEMBL604351)
Affinity DataKi:  34nMAssay Description:Binding affinity towards adenosine A1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Rattus norvegicus (rat))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50368209(CHEMBL2236006 | CHEMBL604768)
Affinity DataKi:  40nMAssay Description:Binding affinity towards adenosine A1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Rattus norvegicus (rat))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50368193(CHEMBL2235611 | CHEMBL604769)
Affinity DataKi:  41nMAssay Description:Binding affinity towards adenosine A1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Rattus norvegicus (rat))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50368221(CHEMBL2235583 | CHEMBL603936)
Affinity DataKi:  41nMAssay Description:Binding affinity towards adenosine A1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Rattus norvegicus (rat))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50368191(CHEMBL2235999 | CHEMBL604352)
Affinity DataKi:  41nMAssay Description:Binding affinity towards adenosine A1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Displayed 1 to 50 (of 1431 total ) | Next | Last >>
Jump to: