TargetMucosa-associated lymphoid tissue lymphoma translocation protein 1(Homo sapiens (Human))
Ku Leuven
Curated by ChEMBL
Ku Leuven
Curated by ChEMBL
Affinity DataKi: 170nMAssay Description:Inhibition of full length wild type human N-terminal GST-tagged MALT1 catalytic domain (325 to 760 residues) expressed in Escherichia coli BL21 (DE3)...More data for this Ligand-Target Pair
TargetMucosa-associated lymphoid tissue lymphoma translocation protein 1(Homo sapiens (Human))
Ku Leuven
Curated by ChEMBL
Ku Leuven
Curated by ChEMBL
Affinity DataKi: 210nMAssay Description:Inhibition of full length wild type human N-terminal GST-tagged MALT1 catalytic domain (325 to 760 residues) expressed in Escherichia coli BL21 (DE3)...More data for this Ligand-Target Pair
Affinity DataKi: 210nMAssay Description:Inhibition of recombinant human cathepsin B expressed in Escherichia coli BL21 (DE3) using zRR-AMC as substrate measured after 2 hrs by fluorescence ...More data for this Ligand-Target Pair
Affinity DataKi: 230nMAssay Description:Inhibition of human liver cathepsin B using Cbz-RR-AMC as substrate by fluorometric assayMore data for this Ligand-Target Pair
TargetMucosa-associated lymphoid tissue lymphoma translocation protein 1(Homo sapiens (Human))
Ku Leuven
Curated by ChEMBL
Ku Leuven
Curated by ChEMBL
Affinity DataKi: 340nMAssay Description:Inhibition of full length wild type human N-terminal GST-tagged MALT1 catalytic domain (325 to 760 residues) expressed in Escherichia coli BL21 (DE3)...More data for this Ligand-Target Pair
Affinity DataKi: 630nMAssay Description:Inhibition of recombinant human cathepsin B expressed in Escherichia coli BL21 (DE3) using zRR-AMC as substrate measured after 2 hrs by fluorescence ...More data for this Ligand-Target Pair
Affinity DataKi: 653nMAssay Description:Inhibition of m-calpain (unknown origin) using Suc-LY-AMC as substrate by fluorometric assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.71E+3nMAssay Description:Inhibition of m-calpain (unknown origin) using Suc-LY-AMC as substrate by fluorometric assayMore data for this Ligand-Target Pair
Affinity DataKi: 2.03E+3nMAssay Description:Inhibition of m-calpain (unknown origin) using Suc-LY-AMC as substrate by fluorometric assayMore data for this Ligand-Target Pair
Affinity DataKi: 2.29E+3nMAssay Description:Inhibition of human liver cathepsin B using Cbz-RR-AMC as substrate by fluorometric assayMore data for this Ligand-Target Pair
Affinity DataKi: 2.98E+3nMAssay Description:Inhibition of m-calpain (unknown origin) using Suc-LY-AMC as substrate by fluorometric assayMore data for this Ligand-Target Pair
Affinity DataKi: 3.05E+3nMAssay Description:Inhibition of human liver cathepsin B using Cbz-RR-AMC as substrate by fluorometric assayMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of recombinant human cathepsin B expressed in Escherichia coli BL21 (DE3) using zRR-AMC as substrate measured after 2 hrs by fluorescence ...More data for this Ligand-Target Pair
Affinity DataKi: 3.03E+4nMAssay Description:Inhibition of human liver cathepsin B using Cbz-RR-AMC as substrate by fluorometric assayMore data for this Ligand-Target Pair
TargetMucosa-associated lymphoid tissue lymphoma translocation protein 1(Homo sapiens (Human))
Ku Leuven
Curated by ChEMBL
Ku Leuven
Curated by ChEMBL
Affinity DataIC50: 420nMAssay Description:Inhibition of GST-MALT1 (325 to 760 residues) (unknown origin) using Ac-LRSR-AMC as substrate by fluorescence analysisMore data for this Ligand-Target Pair
TargetGlutathione S-transferase P/Mucosa-associated lymphoid tissue lymphoma translocation protein 1(Homo sapiens (Human))
Helmholtz Munich
US Patent
Helmholtz Munich
US Patent
Affinity DataIC50: 690nMT: 2°CAssay Description:To screen for small molecular weight compounds that can inhibit MALT1 protease activity, recombinant GSTMALT1 was purified from E. coli to establish ...More data for this Ligand-Target Pair
TargetMucosa-associated lymphoid tissue lymphoma translocation protein 1(Homo sapiens (Human))
Ku Leuven
Curated by ChEMBL
Ku Leuven
Curated by ChEMBL
Affinity DataIC50: 830nMAssay Description:Inhibition of recombinant full length GST-MALT1 (unknown origin) expressed in Escherichia coli using Ac-LRSR-AMC as substrate by fluorescence analysi...More data for this Ligand-Target Pair
TargetGlutathione S-transferase P/Mucosa-associated lymphoid tissue lymphoma translocation protein 1(Homo sapiens (Human))
Helmholtz Munich
US Patent
Helmholtz Munich
US Patent
Affinity DataIC50: 850nMT: 2°CAssay Description:To screen for small molecular weight compounds that can inhibit MALT1 protease activity, recombinant GSTMALT1 was purified from E. coli to establish ...More data for this Ligand-Target Pair
TargetGlutathione S-transferase P/Mucosa-associated lymphoid tissue lymphoma translocation protein 1(Homo sapiens (Human))
Helmholtz Munich
US Patent
Helmholtz Munich
US Patent
Affinity DataIC50: 970nMT: 2°CAssay Description:To screen for small molecular weight compounds that can inhibit MALT1 protease activity, recombinant GSTMALT1 was purified from E. coli to establish ...More data for this Ligand-Target Pair
TargetGlutathione S-transferase P/Mucosa-associated lymphoid tissue lymphoma translocation protein 1(Homo sapiens (Human))
Helmholtz Munich
US Patent
Helmholtz Munich
US Patent
Affinity DataIC50: 973nMT: 2°CAssay Description:To screen for small molecular weight compounds that can inhibit MALT1 protease activity, recombinant GSTMALT1 was purified from E. coli to establish ...More data for this Ligand-Target Pair
TargetGlutathione S-transferase P/Mucosa-associated lymphoid tissue lymphoma translocation protein 1(Homo sapiens (Human))
Helmholtz Munich
US Patent
Helmholtz Munich
US Patent
Affinity DataIC50: 1.18E+3nMT: 2°CAssay Description:To screen for small molecular weight compounds that can inhibit MALT1 protease activity, recombinant GSTMALT1 was purified from E. coli to establish ...More data for this Ligand-Target Pair
TargetGlutathione S-transferase P/Mucosa-associated lymphoid tissue lymphoma translocation protein 1(Homo sapiens (Human))
Helmholtz Munich
US Patent
Helmholtz Munich
US Patent
Affinity DataIC50: 1.42E+3nMT: 2°CAssay Description:To screen for small molecular weight compounds that can inhibit MALT1 protease activity, recombinant GSTMALT1 was purified from E. coli to establish ...More data for this Ligand-Target Pair
TargetMucosa-associated lymphoid tissue lymphoma translocation protein 1(Homo sapiens (Human))
Ku Leuven
Curated by ChEMBL
Ku Leuven
Curated by ChEMBL
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of recombinant Malt1 (unknown origin) at 10 to 1000 uM preincubated for 1 hr followed by (S)-1-((6-(4-(4-(5,5-Difluoro-3,7-bis(4-methoxyph...More data for this Ligand-Target Pair
TargetMucosa-associated lymphoid tissue lymphoma translocation protein 1(Homo sapiens (Human))
Ku Leuven
Curated by ChEMBL
Ku Leuven
Curated by ChEMBL
Affinity DataIC50: 1.51E+3nMAssay Description:Inhibition of recombinant Malt1 (unknown origin) at 10 to 1000 uM preincubated for 1 hr followed by (S)-1-((6-(4-(4-(5,5-Difluoro-3,7-bis(4-methoxyph...More data for this Ligand-Target Pair
TargetMucosa-associated lymphoid tissue lymphoma translocation protein 1(Homo sapiens (Human))
Ku Leuven
Curated by ChEMBL
Ku Leuven
Curated by ChEMBL
Affinity DataIC50: 1.55E+3nMAssay Description:Inhibition of recombinant Malt1 (unknown origin) at 10 to 1000 uM preincubated for 1 hr followed by (S)-1-((6-(4-(4-(5,5-Difluoro-3,7-bis(4-methoxyph...More data for this Ligand-Target Pair
TargetMucosa-associated lymphoid tissue lymphoma translocation protein 1(Homo sapiens (Human))
Ku Leuven
Curated by ChEMBL
Ku Leuven
Curated by ChEMBL
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of recombinant Malt1 (unknown origin) at 10 to 1000 uM preincubated for 1 hr followed by (S)-1-((6-(4-(4-(5,5-Difluoro-3,7-bis(4-methoxyph...More data for this Ligand-Target Pair
TargetGlutathione S-transferase P/Mucosa-associated lymphoid tissue lymphoma translocation protein 1(Homo sapiens (Human))
Helmholtz Munich
US Patent
Helmholtz Munich
US Patent
Affinity DataIC50: 1.75E+3nMT: 2°CAssay Description:To screen for small molecular weight compounds that can inhibit MALT1 protease activity, recombinant GSTMALT1 was purified from E. coli to establish ...More data for this Ligand-Target Pair
TargetGlutathione S-transferase P/Mucosa-associated lymphoid tissue lymphoma translocation protein 1(Homo sapiens (Human))
Helmholtz Munich
US Patent
Helmholtz Munich
US Patent
Affinity DataIC50: 1.85E+3nMT: 2°CAssay Description:To screen for small molecular weight compounds that can inhibit MALT1 protease activity, recombinant GSTMALT1 was purified from E. coli to establish ...More data for this Ligand-Target Pair
TargetGlutathione S-transferase P/Mucosa-associated lymphoid tissue lymphoma translocation protein 1(Homo sapiens (Human))
Helmholtz Munich
US Patent
Helmholtz Munich
US Patent
Affinity DataIC50: 1.85E+3nMT: 2°CAssay Description:To screen for small molecular weight compounds that can inhibit MALT1 protease activity, recombinant GSTMALT1 was purified from E. coli to establish ...More data for this Ligand-Target Pair
TargetGlutathione S-transferase P/Mucosa-associated lymphoid tissue lymphoma translocation protein 1(Homo sapiens (Human))
Helmholtz Munich
US Patent
Helmholtz Munich
US Patent
Affinity DataIC50: 2.00E+3nMT: 2°CAssay Description:To screen for small molecular weight compounds that can inhibit MALT1 protease activity, recombinant GSTMALT1 was purified from E. coli to establish ...More data for this Ligand-Target Pair
TargetMucosa-associated lymphoid tissue lymphoma translocation protein 1(Homo sapiens (Human))
Ku Leuven
Curated by ChEMBL
Ku Leuven
Curated by ChEMBL
Affinity DataIC50: 2.09E+3nMAssay Description:Inhibition of recombinant Malt1 (unknown origin) at 1 to 100 uM preincubated for 1 hr followed by (S)-1-((6-(4-(4-(5,5-Difluoro-3,7-bis(4-methoxyphen...More data for this Ligand-Target Pair
TargetMucosa-associated lymphoid tissue lymphoma translocation protein 1(Homo sapiens (Human))
Ku Leuven
Curated by ChEMBL
Ku Leuven
Curated by ChEMBL
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of recombinant Malt1 (unknown origin) at 1 to 100 uM preincubated for 1 hr followed by (S)-1-((6-(4-(4-(5,5-Difluoro-3,7-bis(4-methoxyphen...More data for this Ligand-Target Pair
TargetGlutathione S-transferase P/Mucosa-associated lymphoid tissue lymphoma translocation protein 1(Homo sapiens (Human))
Helmholtz Munich
US Patent
Helmholtz Munich
US Patent
Affinity DataIC50: 2.40E+3nMT: 2°CAssay Description:To screen for small molecular weight compounds that can inhibit MALT1 protease activity, recombinant GSTMALT1 was purified from E. coli to establish ...More data for this Ligand-Target Pair
TargetGlutathione S-transferase P/Mucosa-associated lymphoid tissue lymphoma translocation protein 1(Homo sapiens (Human))
Helmholtz Munich
US Patent
Helmholtz Munich
US Patent
Affinity DataIC50: 2.41E+3nMT: 2°CAssay Description:To screen for small molecular weight compounds that can inhibit MALT1 protease activity, recombinant GSTMALT1 was purified from E. coli to establish ...More data for this Ligand-Target Pair
TargetGlutathione S-transferase P/Mucosa-associated lymphoid tissue lymphoma translocation protein 1(Homo sapiens (Human))
Helmholtz Munich
US Patent
Helmholtz Munich
US Patent
Affinity DataIC50: 2.50E+3nMT: 2°CAssay Description:To screen for small molecular weight compounds that can inhibit MALT1 protease activity, recombinant GSTMALT1 was purified from E. coli to establish ...More data for this Ligand-Target Pair
TargetGlutathione S-transferase P/Mucosa-associated lymphoid tissue lymphoma translocation protein 1(Homo sapiens (Human))
Helmholtz Munich
US Patent
Helmholtz Munich
US Patent
Affinity DataIC50: 2.67E+3nMT: 2°CAssay Description:To screen for small molecular weight compounds that can inhibit MALT1 protease activity, recombinant GSTMALT1 was purified from E. coli to establish ...More data for this Ligand-Target Pair
TargetGlutathione S-transferase P/Mucosa-associated lymphoid tissue lymphoma translocation protein 1(Homo sapiens (Human))
Helmholtz Munich
US Patent
Helmholtz Munich
US Patent
Affinity DataIC50: 2.67E+3nMT: 2°CAssay Description:To screen for small molecular weight compounds that can inhibit MALT1 protease activity, recombinant GSTMALT1 was purified from E. coli to establish ...More data for this Ligand-Target Pair
TargetGlutathione S-transferase P/Mucosa-associated lymphoid tissue lymphoma translocation protein 1(Homo sapiens (Human))
Helmholtz Munich
US Patent
Helmholtz Munich
US Patent
Affinity DataIC50: 2.77E+3nMT: 2°CAssay Description:To screen for small molecular weight compounds that can inhibit MALT1 protease activity, recombinant GSTMALT1 was purified from E. coli to establish ...More data for this Ligand-Target Pair
TargetMucosa-associated lymphoid tissue lymphoma translocation protein 1(Homo sapiens (Human))
Ku Leuven
Curated by ChEMBL
Ku Leuven
Curated by ChEMBL
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of recombinant Malt1 (unknown origin) at 1 to 100 uM preincubated for 1 hr followed by (S)-1-((6-(4-(4-(5,5-Difluoro-3,7-bis(4-methoxyphen...More data for this Ligand-Target Pair
TargetMucosa-associated lymphoid tissue lymphoma translocation protein 1(Homo sapiens (Human))
Ku Leuven
Curated by ChEMBL
Ku Leuven
Curated by ChEMBL
Affinity DataIC50: 3.02E+3nMAssay Description:Inhibition of recombinant Malt1 (unknown origin) at 1 to 100 uM preincubated for 1 hr followed by (S)-1-((6-(4-(4-(5,5-Difluoro-3,7-bis(4-methoxyphen...More data for this Ligand-Target Pair
TargetGlutathione S-transferase P/Mucosa-associated lymphoid tissue lymphoma translocation protein 1(Homo sapiens (Human))
Helmholtz Munich
US Patent
Helmholtz Munich
US Patent
Affinity DataIC50: 3.43E+3nMT: 2°CAssay Description:To screen for small molecular weight compounds that can inhibit MALT1 protease activity, recombinant GSTMALT1 was purified from E. coli to establish ...More data for this Ligand-Target Pair
TargetGlutathione S-transferase P/Mucosa-associated lymphoid tissue lymphoma translocation protein 1(Homo sapiens (Human))
Helmholtz Munich
US Patent
Helmholtz Munich
US Patent
Affinity DataIC50: 3.86E+3nMT: 2°CAssay Description:To screen for small molecular weight compounds that can inhibit MALT1 protease activity, recombinant GSTMALT1 was purified from E. coli to establish ...More data for this Ligand-Target Pair
TargetGlutathione S-transferase P/Mucosa-associated lymphoid tissue lymphoma translocation protein 1(Homo sapiens (Human))
Helmholtz Munich
US Patent
Helmholtz Munich
US Patent
Affinity DataIC50: 3.88E+3nMT: 2°CAssay Description:To screen for small molecular weight compounds that can inhibit MALT1 protease activity, recombinant GSTMALT1 was purified from E. coli to establish ...More data for this Ligand-Target Pair
TargetGlutathione S-transferase P/Mucosa-associated lymphoid tissue lymphoma translocation protein 1(Homo sapiens (Human))
Helmholtz Munich
US Patent
Helmholtz Munich
US Patent
Affinity DataIC50: 4.00E+3nMT: 2°CAssay Description:To screen for small molecular weight compounds that can inhibit MALT1 protease activity, recombinant GSTMALT1 was purified from E. coli to establish ...More data for this Ligand-Target Pair
TargetGlutathione S-transferase P/Mucosa-associated lymphoid tissue lymphoma translocation protein 1(Homo sapiens (Human))
Helmholtz Munich
US Patent
Helmholtz Munich
US Patent
Affinity DataIC50: 4.17E+3nMT: 2°CAssay Description:To screen for small molecular weight compounds that can inhibit MALT1 protease activity, recombinant GSTMALT1 was purified from E. coli to establish ...More data for this Ligand-Target Pair
TargetGlutathione S-transferase P/Mucosa-associated lymphoid tissue lymphoma translocation protein 1(Homo sapiens (Human))
Helmholtz Munich
US Patent
Helmholtz Munich
US Patent
Affinity DataIC50: 4.22E+3nMT: 2°CAssay Description:To screen for small molecular weight compounds that can inhibit MALT1 protease activity, recombinant GSTMALT1 was purified from E. coli to establish ...More data for this Ligand-Target Pair
TargetGlutathione S-transferase P/Mucosa-associated lymphoid tissue lymphoma translocation protein 1(Homo sapiens (Human))
Helmholtz Munich
US Patent
Helmholtz Munich
US Patent
Affinity DataIC50: 5.70E+3nMT: 2°CAssay Description:To screen for small molecular weight compounds that can inhibit MALT1 protease activity, recombinant GSTMALT1 was purified from E. coli to establish ...More data for this Ligand-Target Pair
TargetGlutathione S-transferase P/Mucosa-associated lymphoid tissue lymphoma translocation protein 1(Homo sapiens (Human))
Helmholtz Munich
US Patent
Helmholtz Munich
US Patent
Affinity DataIC50: 5.75E+3nMT: 2°CAssay Description:To screen for small molecular weight compounds that can inhibit MALT1 protease activity, recombinant GSTMALT1 was purified from E. coli to establish ...More data for this Ligand-Target Pair
TargetGlutathione S-transferase P/Mucosa-associated lymphoid tissue lymphoma translocation protein 1(Homo sapiens (Human))
Helmholtz Munich
US Patent
Helmholtz Munich
US Patent
Affinity DataIC50: 5.80E+3nMT: 2°CAssay Description:To screen for small molecular weight compounds that can inhibit MALT1 protease activity, recombinant GSTMALT1 was purified from E. coli to establish ...More data for this Ligand-Target Pair
TargetGlutathione S-transferase P/Mucosa-associated lymphoid tissue lymphoma translocation protein 1(Homo sapiens (Human))
Helmholtz Munich
US Patent
Helmholtz Munich
US Patent
Affinity DataIC50: 6.25E+3nMT: 2°CAssay Description:To screen for small molecular weight compounds that can inhibit MALT1 protease activity, recombinant GSTMALT1 was purified from E. coli to establish ...More data for this Ligand-Target Pair