Affinity DataIC50: 5nMAssay Description:Inhibition of porcine brain GSK3beta using YRRAAVPPSPSLSRHSSPHQSpEDEEE as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 28nMAssay Description:Inhibition of mammalian CDK5/p25More data for this Ligand-Target Pair
Affinity DataIC50: 70nMAssay Description:Inhibition of porcine brain GSK3beta using YRRAAVPPSPSLSRHSSPHQSpEDEEE as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 83nMAssay Description:Inhibition of mammalian CDK5/p25More data for this Ligand-Target Pair
Affinity DataIC50: 83nMAssay Description:Inhibition of human recombinant CDK5More data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Inhibition of porcine brain GSK3beta using YRRAAVPPSPSLSRHSSPHQSpEDEEE as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Inhibition of mammalian CDK5/p25More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(RAT)
University Of Athens
Curated by ChEMBL
University Of Athens
Curated by ChEMBL
Affinity DataIC50: 110nMAssay Description:Inhibition of rat recombinant GST-fused DYRK1A expressed in Escherichia coli using KKISGRLSPIMTEQ as substrate after 30 mins by scintillation countin...More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(RAT)
University Of Athens
Curated by ChEMBL
University Of Athens
Curated by ChEMBL
Affinity DataIC50: 130nMAssay Description:Inhibition of rat recombinant GST-fused DYRK1A expressed in Escherichia coli using KKISGRLSPIMTEQ as substrate after 30 mins by scintillation countin...More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 2(Homo sapiens (Human))
University Of Athens
Curated by ChEMBL
University Of Athens
Curated by ChEMBL
Affinity DataIC50: 130nMAssay Description:Inhibition of human recombinant GST-fused DYRK2 expressed in Escherichia coli using KKISGRLSPIMTEQ as substrate after 30 mins by scintillation counti...More data for this Ligand-Target Pair
Affinity DataIC50: 200nMAssay Description:Inhibition of human recombinant CDK5More data for this Ligand-Target Pair
Affinity DataIC50: 200nMAssay Description:Inhibition of human recombinant CDK5More data for this Ligand-Target Pair
Affinity DataIC50: 200nMAssay Description:Inhibition of porcine brain GSK3beta using YRRAAVPPSPSLSRHSSPHQSpEDEEE as substrateMore data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(RAT)
University Of Athens
Curated by ChEMBL
University Of Athens
Curated by ChEMBL
Affinity DataIC50: 210nMAssay Description:Inhibition of rat recombinant GST-fused DYRK1A expressed in Escherichia coli using KKISGRLSPIMTEQ as substrate after 30 mins by scintillation countin...More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 2(Homo sapiens (Human))
University Of Athens
Curated by ChEMBL
University Of Athens
Curated by ChEMBL
Affinity DataIC50: 220nMAssay Description:Inhibition of human recombinant GST-fused DYRK2 expressed in Escherichia coli using KKISGRLSPIMTEQ as substrate after 30 mins by scintillation counti...More data for this Ligand-Target Pair
Affinity DataIC50: 300nMAssay Description:Inhibition of porcine brain CK1 using RRKHAAIGpSAYSITA as substrateMore data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(RAT)
University Of Athens
Curated by ChEMBL
University Of Athens
Curated by ChEMBL
Affinity DataIC50: 310nMAssay Description:Inhibition of rat recombinant GST-fused DYRK1A expressed in Escherichia coli using KKISGRLSPIMTEQ as substrate after 30 mins by scintillation countin...More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 2(Homo sapiens (Human))
University Of Athens
Curated by ChEMBL
University Of Athens
Curated by ChEMBL
Affinity DataIC50: 350nMAssay Description:Inhibition of human recombinant GST-fused DYRK2 expressed in Escherichia coli using KKISGRLSPIMTEQ as substrate after 30 mins by scintillation counti...More data for this Ligand-Target Pair
Affinity DataIC50: 400nMAssay Description:Inhibition of human recombinant CDK5More data for this Ligand-Target Pair
Affinity DataIC50: 400nMAssay Description:Inhibition of mammalian CDK5/p25More data for this Ligand-Target Pair
Affinity DataIC50: 400nMAssay Description:Inhibition of porcine brain GSK3beta using YRRAAVPPSPSLSRHSSPHQSpEDEEE as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 400nMAssay Description:Inhibition of porcine brain GSK3beta using YRRAAVPPSPSLSRHSSPHQSpEDEEE as substrateMore data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(RAT)
University Of Athens
Curated by ChEMBL
University Of Athens
Curated by ChEMBL
Affinity DataIC50: 410nMAssay Description:Inhibition of rat recombinant GST-fused DYRK1A expressed in Escherichia coli using KKISGRLSPIMTEQ as substrate after 30 mins by scintillation countin...More data for this Ligand-Target Pair
Affinity DataIC50: 420nMAssay Description:Inhibition of porcine brain CK1 using RRKHAAIGpSAYSITA as substrateMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Friedrich-Schiller-University
Curated by ChEMBL
Friedrich-Schiller-University
Curated by ChEMBL
Affinity DataIC50: 500nMAssay Description:Inhibition of 5-LO in fMLP-stimulated human monocytes assessed as reduction in HETE formationMore data for this Ligand-Target Pair
Affinity DataIC50: 510nMAssay Description:Inhibition of mammalian CDK5/p25More data for this Ligand-Target Pair
Affinity DataIC50: 520nMAssay Description:Inhibition of human recombinant CDK5More data for this Ligand-Target Pair
Affinity DataIC50: 530nMAssay Description:Inhibition of human recombinant CDK5More data for this Ligand-Target Pair
Affinity DataIC50: 580nMAssay Description:Inhibition of porcine brain CK1 using RRKHAAIGpSAYSITA as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 600nMAssay Description:Inhibition of human recombinant CDK5More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Friedrich-Schiller-University
Curated by ChEMBL
Friedrich-Schiller-University
Curated by ChEMBL
Affinity DataIC50: 600nMAssay Description:Inhibition of human recombinant 5-LO assessed as product formation by cell-free assay relative to controlMore data for this Ligand-Target Pair
Affinity DataIC50: 600nMAssay Description:Inhibition of porcine brain GSK3beta using YRRAAVPPSPSLSRHSSPHQSpEDEEE as substrateMore data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(RAT)
University Of Athens
Curated by ChEMBL
University Of Athens
Curated by ChEMBL
Affinity DataIC50: 600nMAssay Description:Inhibition of rat recombinant GST-fused DYRK1A expressed in Escherichia coli using KKISGRLSPIMTEQ as substrate after 30 mins by scintillation countin...More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(RAT)
University Of Athens
Curated by ChEMBL
University Of Athens
Curated by ChEMBL
Affinity DataIC50: 630nMAssay Description:Inhibition of rat recombinant GST-fused DYRK1A expressed in Escherichia coli using KKISGRLSPIMTEQ as substrate after 30 mins by scintillation countin...More data for this Ligand-Target Pair
Affinity DataIC50: 700nMAssay Description:Inhibition of mammalian CDK5/p25More data for this Ligand-Target Pair
Affinity DataIC50: 800nMAssay Description:Inhibition of porcine brain CK1 using RRKHAAIGpSAYSITA as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 800nMAssay Description:Inhibition of porcine brain CK1 using RRKHAAIGpSAYSITA as substrateMore data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 2(Homo sapiens (Human))
University Of Athens
Curated by ChEMBL
University Of Athens
Curated by ChEMBL
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of human recombinant GST-fused DYRK2 expressed in Escherichia coli using KKISGRLSPIMTEQ as substrate after 30 mins by scintillation counti...More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 2(Homo sapiens (Human))
University Of Athens
Curated by ChEMBL
University Of Athens
Curated by ChEMBL
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of human recombinant GST-fused DYRK2 expressed in Escherichia coli using KKISGRLSPIMTEQ as substrate after 30 mins by scintillation counti...More data for this Ligand-Target Pair
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of porcine brain GSK3beta using YRRAAVPPSPSLSRHSSPHQSpEDEEE as substrateMore data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(RAT)
University Of Athens
Curated by ChEMBL
University Of Athens
Curated by ChEMBL
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of rat recombinant GST-fused DYRK1A expressed in Escherichia coli using KKISGRLSPIMTEQ as substrate after 30 mins by scintillation countin...More data for this Ligand-Target Pair
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of porcine brain GSK3beta using YRRAAVPPSPSLSRHSSPHQSpEDEEE as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of porcine brain CK1 using RRKHAAIGpSAYSITA as substrateMore data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 2(Homo sapiens (Human))
University Of Athens
Curated by ChEMBL
University Of Athens
Curated by ChEMBL
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of human recombinant GST-fused DYRK2 expressed in Escherichia coli using KKISGRLSPIMTEQ as substrate after 30 mins by scintillation counti...More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(RAT)
University Of Athens
Curated by ChEMBL
University Of Athens
Curated by ChEMBL
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of rat recombinant GST-fused DYRK1A expressed in Escherichia coli using KKISGRLSPIMTEQ as substrate after 30 mins by scintillation countin...More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 2(Homo sapiens (Human))
University Of Athens
Curated by ChEMBL
University Of Athens
Curated by ChEMBL
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of human recombinant GST-fused DYRK2 expressed in Escherichia coli using KKISGRLSPIMTEQ as substrate after 30 mins by scintillation counti...More data for this Ligand-Target Pair
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of porcine brain CK1 using RRKHAAIGpSAYSITA as substrateMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Friedrich-Schiller-University
Curated by ChEMBL
Friedrich-Schiller-University
Curated by ChEMBL
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of human recombinant 5-LO assessed as product formation by cell-free assay relative to controlMore data for this Ligand-Target Pair