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Found 72 with Last Name = 'kuper' and Initial = 'j'
TargetEnoyl-[acyl-carrier-protein] reductase [NADH](Yersinia pestis (Enterobacteria))
University Of Wurzburg

LigandPNGBDBM50373349(CHEMBL264417 | PT12)
Affinity DataKi:  100nM ΔG°:  -40.0kJ/molepH: 8.0 T: 2°CAssay Description:Steady-state kinetics were performed on a Cary 100 Bio (Varian) spectrometer at 25 °C using 30 mM PIPES, 150 mM NaCl, and 1.0 mM EDTA (pH 8.0) as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADH](Yersinia pestis (Enterobacteria))
University Of Wurzburg

LigandPNGBDBM190659(PT156)
Affinity DataKi:  200nM ΔG°:  -38.2kJ/molepH: 8.0 T: 2°CAssay Description:Steady-state kinetics were performed on a Cary 100 Bio (Varian) spectrometer at 25 °C using 30 mM PIPES, 150 mM NaCl, and 1.0 mM EDTA (pH 8.0) as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADH] [T276S](Yersinia pestis (Enterobacteria))
University Of Wurzburg

LigandPNGBDBM190659(PT156)
Affinity DataKi:  500nM ΔG°:  -36.0kJ/molepH: 8.0 T: 2°CAssay Description:Steady-state kinetics were performed on a Cary 100 Bio (Varian) spectrometer at 25 °C using 30 mM PIPES, 150 mM NaCl, and 1.0 mM EDTA (pH 8.0) as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADH] [T276S](Yersinia pestis (Enterobacteria))
University Of Wurzburg

LigandPNGBDBM190656(PT424)
Affinity DataKi:  3.00E+3nM ΔG°:  -31.5kJ/molepH: 8.0 T: 2°CAssay Description:Steady-state kinetics were performed on a Cary 100 Bio (Varian) spectrometer at 25 °C using 30 mM PIPES, 150 mM NaCl, and 1.0 mM EDTA (pH 8.0) as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADH] [T276S](Yersinia pestis (Enterobacteria))
University Of Wurzburg

LigandPNGBDBM50373349(CHEMBL264417 | PT12)
Affinity DataKi:  4.00E+3nM ΔG°:  -30.8kJ/molepH: 8.0 T: 2°CAssay Description:Steady-state kinetics were performed on a Cary 100 Bio (Varian) spectrometer at 25 °C using 30 mM PIPES, 150 mM NaCl, and 1.0 mM EDTA (pH 8.0) as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADH] [T276S](Yersinia pestis (Enterobacteria))
University Of Wurzburg

LigandPNGBDBM50373349(CHEMBL264417 | PT12)
Affinity DataKi:  8.00E+3nM ΔG°:  -29.1kJ/molepH: 8.0 T: 2°CAssay Description:Steady-state kinetics were performed on a Cary 100 Bio (Varian) spectrometer at 25 °C using 30 mM PIPES, 150 mM NaCl, and 1.0 mM EDTA (pH 8.0) as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADH](Yersinia pestis (Enterobacteria))
University Of Wurzburg

LigandPNGBDBM190656(PT424)
Affinity DataKi:  8.00E+3nM ΔG°:  -29.1kJ/molepH: 8.0 T: 2°CAssay Description:Steady-state kinetics were performed on a Cary 100 Bio (Varian) spectrometer at 25 °C using 30 mM PIPES, 150 mM NaCl, and 1.0 mM EDTA (pH 8.0) as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADH](Yersinia pestis (Enterobacteria))
University Of Wurzburg

LigandPNGBDBM190656(PT424)
Affinity DataKi:  1.60E+4nM ΔG°:  -27.4kJ/molepH: 8.0 T: 2°CAssay Description:Steady-state kinetics were performed on a Cary 100 Bio (Varian) spectrometer at 25 °C using 30 mM PIPES, 150 mM NaCl, and 1.0 mM EDTA (pH 8.0) as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFanconi anemia group J protein(Homo sapiens (Human))
National Institutes Of Health, National Institutes Of Health Biomedical Research Center

LigandPNGBDBM213234(Phen-DC6)
Affinity DataIC50:  0.130nMpH: 8.0Assay Description:Standard helicase reaction mixtures (20μl) containing 5 fmol of the indicated TP-G4 or OX-1-G2' DNA substrates or forked duplex DNA substrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetFanconi anemia group J protein(Homo sapiens (Human))
National Institutes Of Health, National Institutes Of Health Biomedical Research Center

LigandPNGBDBM50376748(CHEMBL259739 | Phen-DC3)
Affinity DataIC50:  0.370nMpH: 8.0Assay Description:Standard helicase reaction mixtures (20μl) containing 5 fmol of the indicated TP-G4 or OX-1-G2' DNA substrates or forked duplex DNA substrat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetATP-dependent DNA helicase DinG(Escherichia coli (Enterobacteria))
National Institutes Of Health, National Institutes Of Health Biomedical Research Center

LigandPNGBDBM213233(Telomestatin (TMS))
Affinity DataIC50:  1nMpH: 8.0Assay Description:Standard helicase reaction mixtures (20μl) containing 5 fmol of the indicated TP-G4 or OX-1-G2' DNA substrates or forked duplex DNA substrat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetATP-dependent DNA helicase DinG(Escherichia coli (Enterobacteria))
National Institutes Of Health, National Institutes Of Health Biomedical Research Center

LigandPNGBDBM213233(Telomestatin (TMS))
Affinity DataIC50:  1.5nMpH: 8.0Assay Description:Standard helicase reaction mixtures (20μl) containing 5 fmol of the indicated TP-G4 or OX-1-G2' DNA substrates or forked duplex DNA substrat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFanconi anemia group J protein(Homo sapiens (Human))
National Institutes Of Health, National Institutes Of Health Biomedical Research Center

LigandPNGBDBM213233(Telomestatin (TMS))
Affinity DataIC50:  1.90nMpH: 8.0Assay Description:Standard helicase reaction mixtures (20μl) containing 5 fmol of the indicated TP-G4 or OX-1-G2' DNA substrates or forked duplex DNA substrat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFanconi anemia group J protein(Homo sapiens (Human))
National Institutes Of Health, National Institutes Of Health Biomedical Research Center

LigandPNGBDBM213233(Telomestatin (TMS))
Affinity DataIC50:  2nMpH: 8.0Assay Description:Standard helicase reaction mixtures (20μl) containing 5 fmol of the indicated TP-G4 or OX-1-G2' DNA substrates or forked duplex DNA substrat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFanconi anemia group J protein(Homo sapiens (Human))
National Institutes Of Health, National Institutes Of Health Biomedical Research Center

LigandPNGBDBM213233(Telomestatin (TMS))
Affinity DataIC50:  2.20nMpH: 8.0Assay Description:Standard helicase reaction mixtures (20μl) containing 5 fmol of the indicated TP-G4 or OX-1-G2' DNA substrates or forked duplex DNA substrat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetATP-dependent DNA helicase DinG(Escherichia coli (Enterobacteria))
National Institutes Of Health, National Institutes Of Health Biomedical Research Center

LigandPNGBDBM50376748(CHEMBL259739 | Phen-DC3)
Affinity DataIC50:  50nMpH: 8.0Assay Description:Standard helicase reaction mixtures (20μl) containing 5 fmol of the indicated TP-G4 or OX-1-G2' DNA substrates or forked duplex DNA substrat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetATP-dependent DNA helicase DinG(Escherichia coli (Enterobacteria))
National Institutes Of Health, National Institutes Of Health Biomedical Research Center

LigandPNGBDBM213234(Phen-DC6)
Affinity DataIC50:  55nMpH: 8.0Assay Description:Standard helicase reaction mixtures (20μl) containing 5 fmol of the indicated TP-G4 or OX-1-G2' DNA substrates or forked duplex DNA substrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetATP-dependent DNA helicase DinG(Escherichia coli (Enterobacteria))
National Institutes Of Health, National Institutes Of Health Biomedical Research Center

LigandPNGBDBM213234(Phen-DC6)
Affinity DataIC50:  60nMpH: 8.0Assay Description:Standard helicase reaction mixtures (20μl) containing 5 fmol of the indicated TP-G4 or OX-1-G2' DNA substrates or forked duplex DNA substrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetFanconi anemia group J protein(Homo sapiens (Human))
National Institutes Of Health, National Institutes Of Health Biomedical Research Center

LigandPNGBDBM50376748(CHEMBL259739 | Phen-DC3)
Affinity DataIC50:  65nMpH: 8.0Assay Description:Standard helicase reaction mixtures (20μl) containing 5 fmol of the indicated TP-G4 or OX-1-G2' DNA substrates or forked duplex DNA substrat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADH](Yersinia pestis (Enterobacteria))
University Of Wurzburg

LigandPNGBDBM190651(LOX inhibitor, 5 | PT113)
Affinity DataIC50:  100nMAssay Description:IC50 values for the inhibition of wildtype and mutant forms of ypFabV were performed by adding varying concentrations of inhibitor dissolved in dimet...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADH](Yersinia pestis (Enterobacteria))
University Of Wurzburg

LigandPNGBDBM190660(PT157)
Affinity DataIC50:  100nMAssay Description:IC50 values for the inhibition of wildtype and mutant forms of ypFabV were performed by adding varying concentrations of inhibitor dissolved in dimet...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFanconi anemia group J protein(Homo sapiens (Human))
National Institutes Of Health, National Institutes Of Health Biomedical Research Center

LigandPNGBDBM213234(Phen-DC6)
Affinity DataIC50:  120nMpH: 8.0Assay Description:Standard helicase reaction mixtures (20μl) containing 5 fmol of the indicated TP-G4 or OX-1-G2' DNA substrates or forked duplex DNA substrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetATP-dependent DNA helicase DinG(Escherichia coli (Enterobacteria))
National Institutes Of Health, National Institutes Of Health Biomedical Research Center

LigandPNGBDBM50376748(CHEMBL259739 | Phen-DC3)
Affinity DataIC50:  130nMpH: 8.0Assay Description:Standard helicase reaction mixtures (20μl) containing 5 fmol of the indicated TP-G4 or OX-1-G2' DNA substrates or forked duplex DNA substrat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFanconi anemia group J protein(Homo sapiens (Human))
National Institutes Of Health, National Institutes Of Health Biomedical Research Center

LigandPNGBDBM213234(Phen-DC6)
Affinity DataIC50:  174nMpH: 8.0Assay Description:Standard helicase reaction mixtures (20μl) containing 5 fmol of the indicated TP-G4 or OX-1-G2' DNA substrates or forked duplex DNA substrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADH](Yersinia pestis (Enterobacteria))
University Of Wurzburg

LigandPNGBDBM190659(PT156)
Affinity DataIC50:  200nMAssay Description:IC50 values for the inhibition of wildtype and mutant forms of ypFabV were performed by adding varying concentrations of inhibitor dissolved in dimet...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADH](Yersinia pestis (Enterobacteria))
University Of Wurzburg

LigandPNGBDBM36543(5-propyl-2-phenoxyphenol | PT02)
Affinity DataIC50:  200nMAssay Description:IC50 values for the inhibition of wildtype and mutant forms of ypFabV were performed by adding varying concentrations of inhibitor dissolved in dimet...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADH](Yersinia pestis (Enterobacteria))
University Of Wurzburg

LigandPNGBDBM50373349(CHEMBL264417 | PT12)
Affinity DataIC50:  200nMAssay Description:IC50 values for the inhibition of wildtype and mutant forms of ypFabV were performed by adding varying concentrations of inhibitor dissolved in dimet...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADH] [T276S](Yersinia pestis (Enterobacteria))
University Of Wurzburg

LigandPNGBDBM190660(PT157)
Affinity DataIC50:  300nMAssay Description:IC50 values for the inhibition of wildtype and mutant forms of ypFabV were performed by adding varying concentrations of inhibitor dissolved in dimet...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFanconi anemia group J protein(Homo sapiens (Human))
National Institutes Of Health, National Institutes Of Health Biomedical Research Center

LigandPNGBDBM50376748(CHEMBL259739 | Phen-DC3)
Affinity DataIC50:  370nMpH: 8.0Assay Description:Standard helicase reaction mixtures (20μl) containing 5 fmol of the indicated TP-G4 or OX-1-G2' DNA substrates or forked duplex DNA substrat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADH](Yersinia pestis (Enterobacteria))
University Of Wurzburg

LigandPNGBDBM16296(5-Pentyl-2-phenoxy-phenol | 5-pentyl-2-phenoxylphe...)
Affinity DataIC50:  1.00E+3nMAssay Description:IC50 values for the inhibition of wildtype and mutant forms of ypFabV were performed by adding varying concentrations of inhibitor dissolved in dimet...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADH](Yersinia pestis (Enterobacteria))
University Of Wurzburg

LigandPNGBDBM50373355(CHEMBL264415 | PT10)
Affinity DataIC50:  1.00E+3nMAssay Description:IC50 values for the inhibition of wildtype and mutant forms of ypFabV were performed by adding varying concentrations of inhibitor dissolved in dimet...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADH] [T276S](Yersinia pestis (Enterobacteria))
University Of Wurzburg

LigandPNGBDBM190654(PT173)
Affinity DataIC50:  1.00E+3nMAssay Description:IC50 values for the inhibition of wildtype and mutant forms of ypFabV were performed by adding varying concentrations of inhibitor dissolved in dimet...More data for this Ligand-Target Pair
TargetEnoyl-[acyl-carrier-protein] reductase [NADH] [T276S](Yersinia pestis (Enterobacteria))
University Of Wurzburg

LigandPNGBDBM190658(PT155)
Affinity DataIC50:  1.00E+3nMAssay Description:IC50 values for the inhibition of wildtype and mutant forms of ypFabV were performed by adding varying concentrations of inhibitor dissolved in dimet...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADH] [T276S](Yersinia pestis (Enterobacteria))
University Of Wurzburg

LigandPNGBDBM190659(PT156)
Affinity DataIC50:  1.00E+3nMAssay Description:IC50 values for the inhibition of wildtype and mutant forms of ypFabV were performed by adding varying concentrations of inhibitor dissolved in dimet...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetATP-dependent DNA helicase DinG(Escherichia coli (Enterobacteria))
National Institutes Of Health, National Institutes Of Health Biomedical Research Center

LigandPNGBDBM50107609(5,10,15,20-tetra(1-methyl-4-pyridyl)-porphyrin | C...)
Affinity DataIC50:  1.10E+3nMpH: 8.0Assay Description:Standard helicase reaction mixtures (20μl) containing 5 fmol of the indicated TP-G4 or OX-1-G2' DNA substrates or forked duplex DNA substrat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetATP-dependent DNA helicase DinG(Escherichia coli (Enterobacteria))
National Institutes Of Health, National Institutes Of Health Biomedical Research Center

LigandPNGBDBM50107609(5,10,15,20-tetra(1-methyl-4-pyridyl)-porphyrin | C...)
Affinity DataIC50:  1.20E+3nMpH: 8.0Assay Description:Standard helicase reaction mixtures (20μl) containing 5 fmol of the indicated TP-G4 or OX-1-G2' DNA substrates or forked duplex DNA substrat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADH] [T276S](Yersinia pestis (Enterobacteria))
University Of Wurzburg

LigandPNGBDBM190653(PT172)
Affinity DataIC50:  2.00E+3nMAssay Description:IC50 values for the inhibition of wildtype and mutant forms of ypFabV were performed by adding varying concentrations of inhibitor dissolved in dimet...More data for this Ligand-Target Pair
TargetEnoyl-[acyl-carrier-protein] reductase [NADH](Yersinia pestis (Enterobacteria))
University Of Wurzburg

LigandPNGBDBM16298(5-Octyl-2-phenoxy-phenol | 5-heptyl-2-phenoxylphen...)
Affinity DataIC50:  2.00E+3nMAssay Description:IC50 values for the inhibition of wildtype and mutant forms of ypFabV were performed by adding varying concentrations of inhibitor dissolved in dimet...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADH](Yersinia pestis (Enterobacteria))
University Of Wurzburg

LigandPNGBDBM50373348(CHEMBL264434 | PT13)
Affinity DataIC50:  2.00E+3nMAssay Description:IC50 values for the inhibition of wildtype and mutant forms of ypFabV were performed by adding varying concentrations of inhibitor dissolved in dimet...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFanconi anemia group J protein(Homo sapiens (Human))
National Institutes Of Health, National Institutes Of Health Biomedical Research Center

LigandPNGBDBM50107609(5,10,15,20-tetra(1-methyl-4-pyridyl)-porphyrin | C...)
Affinity DataIC50:  2.30E+3nMpH: 8.0Assay Description:Standard helicase reaction mixtures (20μl) containing 5 fmol of the indicated TP-G4 or OX-1-G2' DNA substrates or forked duplex DNA substrat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFanconi anemia group J protein(Homo sapiens (Human))
National Institutes Of Health, National Institutes Of Health Biomedical Research Center

LigandPNGBDBM50107609(5,10,15,20-tetra(1-methyl-4-pyridyl)-porphyrin | C...)
Affinity DataIC50:  2.90E+3nMpH: 8.0Assay Description:Standard helicase reaction mixtures (20μl) containing 5 fmol of the indicated TP-G4 or OX-1-G2' DNA substrates or forked duplex DNA substrat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADH](Yersinia pestis (Enterobacteria))
University Of Wurzburg

LigandPNGBDBM50443007(CHEMBL1236225 | PT70)
Affinity DataIC50:  3.00E+3nMAssay Description:IC50 values for the inhibition of wildtype and mutant forms of ypFabV were performed by adding varying concentrations of inhibitor dissolved in dimet...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADH](Yersinia pestis (Enterobacteria))
University Of Wurzburg

LigandPNGBDBM50373347(CHEMBL264175 | PT15)
Affinity DataIC50:  3.00E+3nMAssay Description:IC50 values for the inhibition of wildtype and mutant forms of ypFabV were performed by adding varying concentrations of inhibitor dissolved in dimet...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADH](Yersinia pestis (Enterobacteria))
University Of Wurzburg

LigandPNGBDBM16297(5-Hexyl-2-phenoxy-phenol | 5-hexyl-2-phenoxylpheno...)
Affinity DataIC50:  3.00E+3nMAssay Description:IC50 values for the inhibition of wildtype and mutant forms of ypFabV were performed by adding varying concentrations of inhibitor dissolved in dimet...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADH] [T276S](Yersinia pestis (Enterobacteria))
University Of Wurzburg

LigandPNGBDBM190656(PT424)
Affinity DataIC50:  3.00E+3nMAssay Description:IC50 values for the inhibition of wildtype and mutant forms of ypFabV were performed by adding varying concentrations of inhibitor dissolved in dimet...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADH] [T276S](Yersinia pestis (Enterobacteria))
University Of Wurzburg

LigandPNGBDBM190655(PT179)
Affinity DataIC50:  3.00E+3nMAssay Description:IC50 values for the inhibition of wildtype and mutant forms of ypFabV were performed by adding varying concentrations of inhibitor dissolved in dimet...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADH](Yersinia pestis (Enterobacteria))
University Of Wurzburg

LigandPNGBDBM190650(LOX inhibitor, MLS000545091 | PT91)
Affinity DataIC50:  4.00E+3nMAssay Description:IC50 values for the inhibition of wildtype and mutant forms of ypFabV were performed by adding varying concentrations of inhibitor dissolved in dimet...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetFanconi anemia group J protein(Homo sapiens (Human))
National Institutes Of Health, National Institutes Of Health Biomedical Research Center

LigandPNGBDBM50107609(5,10,15,20-tetra(1-methyl-4-pyridyl)-porphyrin | C...)
Affinity DataIC50:  4.90E+3nMpH: 8.0Assay Description:Standard helicase reaction mixtures (20μl) containing 5 fmol of the indicated TP-G4 or OX-1-G2' DNA substrates or forked duplex DNA substrat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADH] [T276S](Yersinia pestis (Enterobacteria))
University Of Wurzburg

LigandPNGBDBM50373349(CHEMBL264417 | PT12)
Affinity DataIC50:  5.00E+3nMAssay Description:IC50 values for the inhibition of wildtype and mutant forms of ypFabV were performed by adding varying concentrations of inhibitor dissolved in dimet...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADH] [T276S](Yersinia pestis (Enterobacteria))
University Of Wurzburg

LigandPNGBDBM190657(PT425)
Affinity DataIC50:  6.00E+3nMAssay Description:IC50 values for the inhibition of wildtype and mutant forms of ypFabV were performed by adding varying concentrations of inhibitor dissolved in dimet...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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