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Found 6873 with Last Name = 'langgård' and Initial = 'm'
TargetAdenosine receptor A2a(Homo sapiens (Human))
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50202986(2-furan-2-yl-7-(2-{4-[4-(2-methoxy-ethoxy)-phenyl]...)
Affinity DataKi:  5nMAssay Description:Displacement of [3H]-ZM241385 from human adenosine A2A receptor expressed in high five cells after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50336715(4-(3,3-Dimethyl-butyrylamino)-3,5-difluoro-N-thiaz...)
Affinity DataKi:  5.90nMAssay Description:Displacement of [3H]-ZM241385 from human adenosine A2A receptor expressed in high five cells after 30 mins by scintillation countingMore data for this Ligand-Target Pair
TargetAdenosine receptor A2a(Homo sapiens (Human))
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50336712(4-(3,3-Dimethyl-butyrylamino)-3-fluoro-N-thiazol-2...)
Affinity DataKi:  9.20nMAssay Description:Displacement of [3H]-ZM241385 from human adenosine A2A receptor expressed in high five cells after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50336719(4-(3,3-Dimethyl-butyrylamino)-5-fluoro-2-methoxy-N...)
Affinity DataKi:  12nMAssay Description:Displacement of [3H]-ZM241385 from human adenosine A2A receptor expressed in high five cells after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50336717(4-(3,3-Dimethyl-butyrylamino)-3-methoxy-N-thiazol-...)
Affinity DataKi:  17nMAssay Description:Displacement of [3H]-ZM241385 from human adenosine A2A receptor expressed in high five cells after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50336714(4-(3,3-Dimethyl-butyrylamino)-3-methyl-N-thiazol-2...)
Affinity DataKi:  19nMAssay Description:Displacement of [3H]-ZM241385 from human adenosine A2A receptor expressed in high five cells after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50336723(3-Chloro-4-(3,3-dimethyl-butyrylamino)-N-thiazol-2...)
Affinity DataKi:  22nMAssay Description:Displacement of [3H]-ZM241385 from human adenosine A2A receptor expressed in high five cells after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50336720(CHEMBL1671923 | N-(5-Chloro-thiazol-2-yl)-4-(3,3-d...)
Affinity DataKi:  28nMAssay Description:Displacement of [3H]-ZM241385 from human adenosine A2A receptor expressed in high five cells after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50336713(3-Chloro-4-(3,3-dimethyl-butyrylamino)-5-methyl-N-...)
Affinity DataKi:  32nMAssay Description:Displacement of [3H]-ZM241385 from human adenosine A2A receptor expressed in high five cells after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50336729(4-(3,3-Dimethyl-butyrylamino)-N-thiazol-2-yl-benza...)
Affinity DataKi:  36nMAssay Description:Displacement of [3H]-ZM241385 from human adenosine A2A receptor expressed in high five cells after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50336709(4-(3,3-Dimethyl-butyrylamino)-2-methoxy-N-thiazol-...)
Affinity DataKi:  50nMAssay Description:Displacement of [3H]-ZM241385 from human adenosine A2A receptor expressed in high five cells after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50176050(8-(3,4-dimethoxystyryl)-1,3-diethyl-7-methyl-1H-pu...)
Affinity DataKi:  72nMAssay Description:Displacement of [3H]-ZM241385 from human adenosine A2A receptor expressed in high five cells after 30 mins by scintillation countingMore data for this Ligand-Target Pair
TargetSortilin(Homo sapiens (Human))
H. Lundbeck

US Patent
LigandPNGBDBM159226(US10195186, Example 46 | US9682967, 44)
Affinity DataKi:  84nMAssay Description:The Sortilin assay was performed in total volume of 40 ul in 50 mM HEPES pH 7.4 assay buffer containing 100 mM NaCl, 2.0 mM CaCl2, 0.1% BSA and 0.1% ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenosine receptor A2a(Homo sapiens (Human))
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50336728(4-(3-Methyl-butyrylamino)-N-thiazol-2-yl-benzamide...)
Affinity DataKi:  90nMAssay Description:Displacement of [3H]-ZM241385 from human adenosine A2A receptor expressed in high five cells after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50336727(CHEMBL1671928 | N-(2,2-Dimethyl-propyl)-N'-thiazol...)
Affinity DataKi:  110nMAssay Description:Displacement of [3H]-ZM241385 from human adenosine A2A receptor expressed in high five cells after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50336710(4-(3,3-Dimethyl-butyrylamino)-N-(5-methyl-thiazol-...)
Affinity DataKi:  120nMAssay Description:Displacement of [3H]-ZM241385 from human adenosine A2A receptor expressed in high five cells after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSortilin(Homo sapiens (Human))
H. Lundbeck

US Patent
LigandPNGBDBM50445042(CHEMBL3098767 | US10195186, Example 7 | US9682967,...)
Affinity DataKi:  162nMAssay Description:The Sortilin assay was performed in total volume of 40 ul in 50 mM HEPES pH 7.4 assay buffer containing 100 mM NaCl, 2.0 mM CaCl2, 0.1% BSA and 0.1% ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAdenosine receptor A2a(Homo sapiens (Human))
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50336726(2-Chloro-4-(3,3-dimethyl-butyrylamino)-N-thiazol-2...)
Affinity DataKi:  180nMAssay Description:Displacement of [3H]-ZM241385 from human adenosine A2A receptor expressed in high five cells after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50336725(4-pentanamido-N-(thiazol-2-yl)benzamide | CHEMBL16...)
Affinity DataKi:  190nMAssay Description:Displacement of [3H]-ZM241385 from human adenosine A2A receptor expressed in high five cells after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSortilin(Homo sapiens (Human))
H. Lundbeck

US Patent
LigandPNGBDBM50445055(CHEMBL3098744 | US10195186, Example 45 | US9682967...)
Affinity DataKi:  190nMAssay Description:The Sortilin assay was performed in total volume of 40 ul in 50 mM HEPES pH 7.4 assay buffer containing 100 mM NaCl, 2.0 mM CaCl2, 0.1% BSA and 0.1% ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAdenosine receptor A2a(Homo sapiens (Human))
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50336724(4-(3,3-Dimethyl-butyrylamino)-2-methyl-N-thiazol-2...)
Affinity DataKi:  200nMAssay Description:Displacement of [3H]-ZM241385 from human adenosine A2A receptor expressed in high five cells after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSortilin(Mouse)
H. Lundbeck

US Patent
LigandPNGBDBM50445054(CHEMBL3098745 | US10195186, Example 1 | US9682967,...)
Affinity DataKi:  210nMAssay Description:The Sortilin assay was performed in total volume of 40 μl in 50 mM HEPES pH 7.4 assay buffer containing 100 mM NaCl, 2.0 mM CaCl2, 0.1% BSA and ...More data for this Ligand-Target Pair
TargetAdenosine receptor A1(Homo sapiens (Human))
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50336723(3-Chloro-4-(3,3-dimethyl-butyrylamino)-N-thiazol-2...)
Affinity DataKi:  210nMAssay Description:Displacement of [3H]-DPCPX from human adenosine A1 receptor expressed in CHO cells after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50336722(2-methyl-N-(4-(thiazol-2-ylcarbamoyl)phenyl)benzam...)
Affinity DataKi:  220nMAssay Description:Displacement of [3H]-ZM241385 from human adenosine A2A receptor expressed in high five cells after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50336721(4-(3,3-Dimethyl-butyrylamino)-N-(4,5-dimethyl-thia...)
Affinity DataKi:  220nMAssay Description:Displacement of [3H]-ZM241385 from human adenosine A2A receptor expressed in high five cells after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50336719(4-(3,3-Dimethyl-butyrylamino)-5-fluoro-2-methoxy-N...)
Affinity DataKi:  220nMAssay Description:Displacement of [3H]-DPCPX from human adenosine A1 receptor expressed in CHO cells after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50336720(CHEMBL1671923 | N-(5-Chloro-thiazol-2-yl)-4-(3,3-d...)
Affinity DataKi:  220nMAssay Description:Displacement of [3H]-DPCPX from human adenosine A1 receptor expressed in CHO cells after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSortilin(Homo sapiens (Human))
H. Lundbeck

US Patent
LigandPNGBDBM159140(US10195186, Example 18 | US9682967, 18)
Affinity DataKi:  229nMAssay Description:The Sortilin assay was performed in total volume of 40 ul in 50 mM HEPES pH 7.4 assay buffer containing 100 mM NaCl, 2.0 mM CaCl2, 0.1% BSA and 0.1% ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenosine receptor A2b(Homo sapiens (Human))
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50336715(4-(3,3-Dimethyl-butyrylamino)-3,5-difluoro-N-thiaz...)
Affinity DataKi:  260nMAssay Description:Displacement of [3H]-MRS1754 from human recombinant adenosine A2B receptor expressed in HEK293 cells after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSortilin(Homo sapiens (Human))
H. Lundbeck

US Patent
LigandPNGBDBM159213(US10195186, Example 44 | US9682967, 42)
Affinity DataKi:  286nMAssay Description:The Sortilin assay was performed in total volume of 40 ul in 50 mM HEPES pH 7.4 assay buffer containing 100 mM NaCl, 2.0 mM CaCl2, 0.1% BSA and 0.1% ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenosine receptor A2a(Homo sapiens (Human))
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50336718(4-Isobutyrylamino-N-thiazol-2-yl-benzamide | CHEMB...)
Affinity DataKi:  300nMAssay Description:Displacement of [3H]-ZM241385 from human adenosine A2A receptor expressed in high five cells after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50336717(4-(3,3-Dimethyl-butyrylamino)-3-methoxy-N-thiazol-...)
Affinity DataKi:  340nMAssay Description:Displacement of [3H]-DPCPX from human adenosine A1 receptor expressed in CHO cells after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSortilin(Homo sapiens (Human))
H. Lundbeck

US Patent
LigandPNGBDBM159138(US10195186, Example 16 | US9682967, 16)
Affinity DataKi:  343nMAssay Description:The Sortilin assay was performed in total volume of 40 ul in 50 mM HEPES pH 7.4 assay buffer containing 100 mM NaCl, 2.0 mM CaCl2, 0.1% BSA and 0.1% ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSortilin(Homo sapiens (Human))
H. Lundbeck

US Patent
LigandPNGBDBM159139(US10195186, Example 17 | US9682967, 17)
Affinity DataKi:  343nMAssay Description:The Sortilin assay was performed in total volume of 40 ul in 50 mM HEPES pH 7.4 assay buffer containing 100 mM NaCl, 2.0 mM CaCl2, 0.1% BSA and 0.1% ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenosine receptor A2a(Homo sapiens (Human))
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50336716(4-Butyrylamino-N-thiazol-2-yl-benzamide | CHEMBL16...)
Affinity DataKi:  350nMAssay Description:Displacement of [3H]-ZM241385 from human adenosine A2A receptor expressed in high five cells after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50336715(4-(3,3-Dimethyl-butyrylamino)-3,5-difluoro-N-thiaz...)
Affinity DataKi:  410nMAssay Description:Displacement of [3H]-DPCPX from human adenosine A1 receptor expressed in CHO cells after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSortilin(Homo sapiens (Human))
H. Lundbeck

US Patent
LigandPNGBDBM50445054(CHEMBL3098745 | US10195186, Example 1 | US9682967,...)
Affinity DataKi:  429nMAssay Description:The Sortilin assay was performed in total volume of 40 ul in 50 mM HEPES pH 7.4 assay buffer containing 100 mM NaCl, 2.0 mM CaCl2, 0.1% BSA and 0.1% ...More data for this Ligand-Target Pair
TargetSortilin(Homo sapiens (Human))
H. Lundbeck

US Patent
LigandPNGBDBM159123(US10195186, Example 11 | US9682967, 11)
Affinity DataKi:  457nMAssay Description:The Sortilin assay was performed in total volume of 40 ul in 50 mM HEPES pH 7.4 assay buffer containing 100 mM NaCl, 2.0 mM CaCl2, 0.1% BSA and 0.1% ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSortilin(Homo sapiens (Human))
H. Lundbeck

US Patent
LigandPNGBDBM159129(US10195186, Example 13 | US9682967, 13)
Affinity DataKi:  457nMAssay Description:The Sortilin assay was performed in total volume of 40 ul in 50 mM HEPES pH 7.4 assay buffer containing 100 mM NaCl, 2.0 mM CaCl2, 0.1% BSA and 0.1% ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenosine receptor A1(Homo sapiens (Human))
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50336714(4-(3,3-Dimethyl-butyrylamino)-3-methyl-N-thiazol-2...)
Affinity DataKi:  460nMAssay Description:Displacement of [3H]-DPCPX from human adenosine A1 receptor expressed in CHO cells after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSortilin(Homo sapiens (Human))
H. Lundbeck

US Patent
LigandPNGBDBM159178(US10195186, Example 34 | US9682967, 32)
Affinity DataKi:  467nMAssay Description:The Sortilin assay was performed in total volume of 40 ul in 50 mM HEPES pH 7.4 assay buffer containing 100 mM NaCl, 2.0 mM CaCl2, 0.1% BSA and 0.1% ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSortilin(Homo sapiens (Human))
H. Lundbeck

US Patent
LigandPNGBDBM159154(US10195186, Example 23 | US9682967, 23)
Affinity DataKi:  543nMAssay Description:The Sortilin assay was performed in total volume of 40 ul in 50 mM HEPES pH 7.4 assay buffer containing 100 mM NaCl, 2.0 mM CaCl2, 0.1% BSA and 0.1% ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenosine receptor A1(Homo sapiens (Human))
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50336713(3-Chloro-4-(3,3-dimethyl-butyrylamino)-5-methyl-N-...)
Affinity DataKi:  580nMAssay Description:Displacement of [3H]-DPCPX from human adenosine A1 receptor expressed in CHO cells after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSortilin(Homo sapiens (Human))
H. Lundbeck

US Patent
LigandPNGBDBM159272(US10195186, Example 50 | US9682967, 48)
Affinity DataKi:  599nMAssay Description:The Sortilin assay was performed in total volume of 40 ul in 50 mM HEPES pH 7.4 assay buffer containing 100 mM NaCl, 2.0 mM CaCl2, 0.1% BSA and 0.1% ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSortilin(Homo sapiens (Human))
H. Lundbeck

US Patent
LigandPNGBDBM159273(US10195186, Example 51 | US9682967, 49)
Affinity DataKi:  614nMAssay Description:The Sortilin assay was performed in total volume of 40 ul in 50 mM HEPES pH 7.4 assay buffer containing 100 mM NaCl, 2.0 mM CaCl2, 0.1% BSA and 0.1% ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenosine receptor A1(Homo sapiens (Human))
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50336712(4-(3,3-Dimethyl-butyrylamino)-3-fluoro-N-thiazol-2...)
Affinity DataKi:  650nMAssay Description:Displacement of [3H]-DPCPX from human adenosine A1 receptor expressed in CHO cells after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSortilin(Homo sapiens (Human))
H. Lundbeck

US Patent
LigandPNGBDBM159121(US10195186, Example 9 | US9682967, 9)
Affinity DataKi:  667nMAssay Description:The Sortilin assay was performed in total volume of 40 ul in 50 mM HEPES pH 7.4 assay buffer containing 100 mM NaCl, 2.0 mM CaCl2, 0.1% BSA and 0.1% ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSortilin(Homo sapiens (Human))
H. Lundbeck

US Patent
LigandPNGBDBM50445044(CHEMBL3098765 | US10195186, Example 36 | US9682967...)
Affinity DataKi:  714nMAssay Description:The Sortilin assay was performed in total volume of 40 ul in 50 mM HEPES pH 7.4 assay buffer containing 100 mM NaCl, 2.0 mM CaCl2, 0.1% BSA and 0.1% ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSortilin(Homo sapiens (Human))
H. Lundbeck

US Patent
LigandPNGBDBM50445041(CHEMBL3098768 | US10195186, Example 48 | US9682967...)
Affinity DataKi:  721nMAssay Description:The Sortilin assay was performed in total volume of 40 ul in 50 mM HEPES pH 7.4 assay buffer containing 100 mM NaCl, 2.0 mM CaCl2, 0.1% BSA and 0.1% ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSortilin(Homo sapiens (Human))
H. Lundbeck

US Patent
LigandPNGBDBM159271(US10195186, Example 49 | US9682967, 47)
Affinity DataKi:  734nMAssay Description:The Sortilin assay was performed in total volume of 40 ul in 50 mM HEPES pH 7.4 assay buffer containing 100 mM NaCl, 2.0 mM CaCl2, 0.1% BSA and 0.1% ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
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