TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Abbvie Deutschland
Curated by ChEMBL
Abbvie Deutschland
Curated by ChEMBL
Affinity DataKi: 0.800nMAssay Description:Displacement of [3H]N-Methyl-SSR504734 from human GlyT1c expressed in cell membranes incubated for 1 hr by liquid scintillation spectrometryMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Abbvie Deutschland
Curated by ChEMBL
Abbvie Deutschland
Curated by ChEMBL
Affinity DataKi: 0.800nMAssay Description:Displacement of [3H]N-Methyl-SSR504734 from human GlyT1c expressed in cell membranes incubated for 1 hr by liquid scintillation spectrometryMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Abbvie Deutschland
Curated by ChEMBL
Abbvie Deutschland
Curated by ChEMBL
Affinity DataKi: 0.900nMAssay Description:Displacement of [3H]N-Methyl-SSR504734 from human GlyT1c expressed in cell membranes incubated for 1 hr by liquid scintillation spectrometryMore data for this Ligand-Target Pair
TargetAlpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase(Homo sapiens (Human))
Abbvie
US Patent
Abbvie
US Patent
Affinity DataKi: <1nMAssay Description:Radioligand binding assays using recombinant CHO cell membranes expressing human GlyT1: Radioligand binding to human GlyT1c transporter-expressing me...More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Abbvie Deutschland
Curated by ChEMBL
Abbvie Deutschland
Curated by ChEMBL
Affinity DataKi: 1nMAssay Description:Inhibition of [3H]N-Methyl-SSR504734 binding to human recombinant GlyT1c expressed in CHO cell membranes incubated for 1 hr by liquid scintillation s...More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Abbvie Deutschland
Curated by ChEMBL
Abbvie Deutschland
Curated by ChEMBL
Affinity DataKi: 1.10nMAssay Description:Displacement of [3H]N-Methyl-SSR504734 from human GlyT1c expressed in cell membranes incubated for 1 hr by liquid scintillation spectrometryMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Abbvie Deutschland
Curated by ChEMBL
Abbvie Deutschland
Curated by ChEMBL
Affinity DataKi: 1.20nMAssay Description:Displacement of [3H]N-Methyl-SSR504734 from human GlyT1c expressed in cell membranes incubated for 1 hr by liquid scintillation spectrometryMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Abbvie Deutschland
Curated by ChEMBL
Abbvie Deutschland
Curated by ChEMBL
Affinity DataKi: 1.20nMAssay Description:Displacement of [3H]N-Methyl-SSR504734 from human GlyT1c expressed in cell membranes incubated for 1 hr by liquid scintillation spectrometryMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Abbvie Deutschland
Curated by ChEMBL
Abbvie Deutschland
Curated by ChEMBL
Affinity DataKi: 1.20nMAssay Description:Displacement of [3H]N-Methyl-SSR504734 from human GlyT1c expressed in cell membranes incubated for 1 hr by liquid scintillation spectrometryMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Abbvie Deutschland
Curated by ChEMBL
Abbvie Deutschland
Curated by ChEMBL
Affinity DataKi: 1.20nMAssay Description:Displacement of [3H]N-Methyl-SSR504734 from human GlyT1c expressed in cell membranes incubated for 1 hr by liquid scintillation spectrometryMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Abbvie Deutschland
Curated by ChEMBL
Abbvie Deutschland
Curated by ChEMBL
Affinity DataKi: 1.5nMAssay Description:Displacement of [3H]N-Methyl-SSR504734 from human GlyT1c expressed in cell membranes incubated for 1 hr by liquid scintillation spectrometryMore data for this Ligand-Target Pair
Affinity DataKi: 1.80nMAssay Description:Inhibition of human procathepsin K expressed in Escherichia coli using Z-Gly-Pro-Arg-AMC as substrate by kinetic fluorescence assayMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Abbvie Deutschland
Curated by ChEMBL
Abbvie Deutschland
Curated by ChEMBL
Affinity DataKi: 2nMAssay Description:Inhibition of [3H]N-Methyl-SSR504734 binding to human recombinant GlyT1c expressed in CHO cell membranes incubated for 1 hr by liquid scintillation s...More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Abbvie Deutschland
Curated by ChEMBL
Abbvie Deutschland
Curated by ChEMBL
Affinity DataKi: 2nMAssay Description:Inhibition of [3H]N-Methyl-SSR504734 binding to human recombinant GlyT1c expressed in CHO cell membranes incubated for 1 hr by liquid scintillation s...More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Abbvie Deutschland
Curated by ChEMBL
Abbvie Deutschland
Curated by ChEMBL
Affinity DataKi: 2nMAssay Description:Inhibition of [3H]N-Methyl-SSR504734 binding to human recombinant GlyT1c expressed in CHO cell membranes incubated for 1 hr by liquid scintillation s...More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Abbvie Deutschland
Curated by ChEMBL
Abbvie Deutschland
Curated by ChEMBL
Affinity DataKi: 2nMAssay Description:Inhibition of [3H]N-Methyl-SSR504734 binding to human recombinant GlyT1c expressed in CHO cell membranes incubated for 1 hr by liquid scintillation s...More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Abbvie Deutschland
Curated by ChEMBL
Abbvie Deutschland
Curated by ChEMBL
Affinity DataKi: 2.60nMAssay Description:Displacement of [3H]N-Methyl-SSR504734 from human GlyT1c expressed in cell membranes incubated for 1 hr by liquid scintillation spectrometryMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Abbvie Deutschland
Curated by ChEMBL
Abbvie Deutschland
Curated by ChEMBL
Affinity DataKi: 2.60nMAssay Description:Displacement of [3H]N-Methyl-SSR504734 from human GlyT1c expressed in cell membranes incubated for 1 hr by liquid scintillation spectrometryMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Abbvie Deutschland
Curated by ChEMBL
Abbvie Deutschland
Curated by ChEMBL
Affinity DataKi: 2.60nMAssay Description:Displacement of [3H]N-Methyl-SSR504734 from human GlyT1c expressed in cell membranes incubated for 1 hr by liquid scintillation spectrometryMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Abbvie Deutschland
Curated by ChEMBL
Abbvie Deutschland
Curated by ChEMBL
Affinity DataKi: 3nMAssay Description:Displacement of [3H]N-Methyl-SSR504734 from human GlyT1c expressed in cell membranes incubated for 1 hr by liquid scintillation spectrometryMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Abbvie Deutschland
Curated by ChEMBL
Abbvie Deutschland
Curated by ChEMBL
Affinity DataKi: 3nMAssay Description:Inhibition of [3H]N-Methyl-SSR504734 binding to human recombinant GlyT1c expressed in CHO cell membranes incubated for 1 hr by liquid scintillation s...More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Abbvie Deutschland
Curated by ChEMBL
Abbvie Deutschland
Curated by ChEMBL
Affinity DataKi: 3nMAssay Description:Inhibition of [3H]N-Methyl-SSR504734 binding to human recombinant GlyT1c expressed in CHO cell membranes incubated for 1 hr by liquid scintillation s...More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Abbvie Deutschland
Curated by ChEMBL
Abbvie Deutschland
Curated by ChEMBL
Affinity DataKi: 3nMAssay Description:Inhibition of [3H]N-Methyl-SSR504734 binding to human recombinant GlyT1c expressed in CHO cell membranes incubated for 1 hr by liquid scintillation s...More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Abbvie Deutschland
Curated by ChEMBL
Abbvie Deutschland
Curated by ChEMBL
Affinity DataKi: 3nMAssay Description:Inhibition of [3H]N-Methyl-SSR504734 binding to human recombinant GlyT1c expressed in CHO cell membranes incubated for 1 hr by liquid scintillation s...More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Abbvie Deutschland
Curated by ChEMBL
Abbvie Deutschland
Curated by ChEMBL
Affinity DataKi: 3nMAssay Description:Displacement of [3H]N-Methyl-SSR504734 from human GlyT1c expressed in cell membranes incubated for 1 hr by liquid scintillation spectrometryMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Abbvie Deutschland
Curated by ChEMBL
Abbvie Deutschland
Curated by ChEMBL
Affinity DataKi: 3.30nMAssay Description:Displacement of [3H]N-Methyl-SSR504734 from human GlyT1c expressed in cell membranes incubated for 1 hr by liquid scintillation spectrometryMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Abbvie Deutschland
Curated by ChEMBL
Abbvie Deutschland
Curated by ChEMBL
Affinity DataKi: 3.60nMAssay Description:Displacement of [3H]N-Methyl-SSR504734 from human GlyT1c expressed in cell membranes incubated for 1 hr by liquid scintillation spectrometryMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Abbvie Deutschland
Curated by ChEMBL
Abbvie Deutschland
Curated by ChEMBL
Affinity DataKi: 4nMAssay Description:Inhibition of [3H]N-Methyl-SSR504734 binding to human recombinant GlyT1c expressed in CHO cell membranes incubated for 1 hr by liquid scintillation s...More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Abbvie Deutschland
Curated by ChEMBL
Abbvie Deutschland
Curated by ChEMBL
Affinity DataKi: 5nMAssay Description:Inhibition of [3H]N-Methyl-SSR504734 binding to human recombinant GlyT1c expressed in CHO cell membranes incubated for 1 hr by liquid scintillation s...More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Abbvie Deutschland
Curated by ChEMBL
Abbvie Deutschland
Curated by ChEMBL
Affinity DataKi: 5nMAssay Description:Inhibition of [3H]N-Methyl-SSR504734 binding to human recombinant GlyT1c expressed in CHO cell membranes incubated for 1 hr by liquid scintillation s...More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Abbvie Deutschland
Curated by ChEMBL
Abbvie Deutschland
Curated by ChEMBL
Affinity DataKi: 5.70nMAssay Description:Displacement of [3H]N-Methyl-SSR504734 from human GlyT1c expressed in cell membranes incubated for 1 hr by liquid scintillation spectrometryMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Abbvie Deutschland
Curated by ChEMBL
Abbvie Deutschland
Curated by ChEMBL
Affinity DataKi: 7nMAssay Description:Inhibition of [3H]N-Methyl-SSR504734 binding to human recombinant GlyT1c expressed in CHO cell membranes incubated for 1 hr by liquid scintillation s...More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Abbvie Deutschland
Curated by ChEMBL
Abbvie Deutschland
Curated by ChEMBL
Affinity DataKi: 8nMAssay Description:Inhibition of [3H]N-Methyl-SSR504734 binding to human recombinant GlyT1c expressed in CHO cell membranes incubated for 1 hr by liquid scintillation s...More data for this Ligand-Target Pair
Affinity DataKi: 8nMAssay Description:Inhibition of human erythrocytes calpain-1 using Suc-Leu-Tyr-AMC as substrate by kinetic fluorescence assayMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Abbvie Deutschland
Curated by ChEMBL
Abbvie Deutschland
Curated by ChEMBL
Affinity DataKi: 8nMAssay Description:Inhibition of [3H]N-Methyl-SSR504734 binding to human recombinant GlyT1c expressed in CHO cell membranes incubated for 1 hr by liquid scintillation s...More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Abbvie Deutschland
Curated by ChEMBL
Abbvie Deutschland
Curated by ChEMBL
Affinity DataKi: 9.5nMAssay Description:Displacement of [3H]N-Methyl-SSR504734 from human GlyT1c expressed in cell membranes incubated for 1 hr by liquid scintillation spectrometryMore data for this Ligand-Target Pair
TargetAlpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase(Homo sapiens (Human))
Abbvie
US Patent
Abbvie
US Patent
Affinity DataKi: <10nMAssay Description:Radioligand binding assays using recombinant CHO cell membranes expressing human GlyT1: Radioligand binding to human GlyT1c transporter-expressing me...More data for this Ligand-Target Pair
TargetAlpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase(Homo sapiens (Human))
Abbvie
US Patent
Abbvie
US Patent
Affinity DataKi: <10nMAssay Description:Radioligand binding assays using recombinant CHO cell membranes expressing human GlyT1: Radioligand binding to human GlyT1c transporter-expressing me...More data for this Ligand-Target Pair
TargetAlpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase(Homo sapiens (Human))
Abbvie
US Patent
Abbvie
US Patent
Affinity DataKi: <10nMAssay Description:Radioligand binding assays using recombinant CHO cell membranes expressing human GlyT1: Radioligand binding to human GlyT1c transporter-expressing me...More data for this Ligand-Target Pair
TargetAlpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase(Homo sapiens (Human))
Abbvie
US Patent
Abbvie
US Patent
Affinity DataKi: <10nMAssay Description:Radioligand binding assays using recombinant CHO cell membranes expressing human GlyT1: Radioligand binding to human GlyT1c transporter-expressing me...More data for this Ligand-Target Pair
TargetAlpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase(Homo sapiens (Human))
Abbvie
US Patent
Abbvie
US Patent
Affinity DataKi: <10nMAssay Description:Radioligand binding assays using recombinant CHO cell membranes expressing human GlyT1: Radioligand binding to human GlyT1c transporter-expressing me...More data for this Ligand-Target Pair
TargetAlpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase(Homo sapiens (Human))
Abbvie
US Patent
Abbvie
US Patent
Affinity DataKi: <10nMAssay Description:Radioligand binding assays using recombinant CHO cell membranes expressing human GlyT1: Radioligand binding to human GlyT1c transporter-expressing me...More data for this Ligand-Target Pair
TargetAlpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase(Homo sapiens (Human))
Abbvie
US Patent
Abbvie
US Patent
Affinity DataKi: <10nMAssay Description:Radioligand binding assays using recombinant CHO cell membranes expressing human GlyT1: Radioligand binding to human GlyT1c transporter-expressing me...More data for this Ligand-Target Pair
TargetAlpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase(Homo sapiens (Human))
Abbvie
US Patent
Abbvie
US Patent
Affinity DataKi: <10nMAssay Description:Radioligand binding assays using recombinant CHO cell membranes expressing human GlyT1: Radioligand binding to human GlyT1c transporter-expressing me...More data for this Ligand-Target Pair
TargetAlpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase(Homo sapiens (Human))
Abbvie
US Patent
Abbvie
US Patent
Affinity DataKi: <10nMAssay Description:Radioligand binding assays using recombinant CHO cell membranes expressing human GlyT1: Radioligand binding to human GlyT1c transporter-expressing me...More data for this Ligand-Target Pair
TargetAlpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase(Homo sapiens (Human))
Abbvie
US Patent
Abbvie
US Patent
Affinity DataKi: <10nMAssay Description:Radioligand binding assays using recombinant CHO cell membranes expressing human GlyT1: Radioligand binding to human GlyT1c transporter-expressing me...More data for this Ligand-Target Pair
TargetAlpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase(Homo sapiens (Human))
Abbvie
US Patent
Abbvie
US Patent
Affinity DataKi: <10nMAssay Description:Radioligand binding assays using recombinant CHO cell membranes expressing human GlyT1: Radioligand binding to human GlyT1c transporter-expressing me...More data for this Ligand-Target Pair
TargetAlpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase(Homo sapiens (Human))
Abbvie
US Patent
Abbvie
US Patent
Affinity DataKi: <10nMAssay Description:Radioligand binding assays using recombinant CHO cell membranes expressing human GlyT1: Radioligand binding to human GlyT1c transporter-expressing me...More data for this Ligand-Target Pair
TargetAlpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase(Homo sapiens (Human))
Abbvie
US Patent
Abbvie
US Patent
Affinity DataKi: <10nMAssay Description:Radioligand binding assays using recombinant CHO cell membranes expressing human GlyT1: Radioligand binding to human GlyT1c transporter-expressing me...More data for this Ligand-Target Pair
TargetAlpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase(Homo sapiens (Human))
Abbvie
US Patent
Abbvie
US Patent
Affinity DataKi: <10nMAssay Description:Radioligand binding assays using recombinant CHO cell membranes expressing human GlyT1: Radioligand binding to human GlyT1c transporter-expressing me...More data for this Ligand-Target Pair