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Found 304 with Last Name = 'lee' and Initial = 'jo'
TargetDipeptidyl peptidase 4(Sus scrofa (pig))
Korea Research Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50206821((R)-3-amino-1-(2-benzoylpiperazin-1-yl)-4-(2,4,5-t...)
Affinity DataKi:  44nMAssay Description:Inhibition of pig kidney DPP4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Sus scrofa (pig))
Korea Research Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50206820((R)-3-amino-1-(2-benzoyl-1,2-diazepan-1-yl)-4-(2,4...)
Affinity DataKi:  56.2nMAssay Description:Inhibition of pig kidney DPP4More data for this Ligand-Target Pair
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50337787((R)-2-(4-(((S)-3-((R)-3-amino-4-(2,4,5-trifluoroph...)
Affinity DataIC50:  1nMAssay Description:Inhibition of human recombinant DPP4 after 60 mins by fluorescence plate readerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50337789((S)-2-(4-(((S)-3-((R)-3-amino-4-(2,4,5-trifluoroph...)
Affinity DataIC50:  1.20nMAssay Description:Inhibition of human recombinant DPP4 after 60 mins by fluorescence plate readerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Yangji Chemicals

Curated by ChEMBL
LigandPNGBDBM50315021((R)-N-(2-(1-(2-(4-(2-chlorobenzoyl)piperazin-1-yl)...)
Affinity DataIC50:  1.70nMAssay Description:Antagonist activity at human CCR2B receptor expressed in HEK293 cells assessed as inhibition of MCP1-induced increase in intracellular calcium levelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Yangji Chemicals

Curated by ChEMBL
LigandPNGBDBM50315022((R)-N-(2-(1-(2-(4-(2-fluorobenzoyl)piperazin-1-yl)...)
Affinity DataIC50:  2.60nMAssay Description:Antagonist activity at human CCR2B receptor expressed in HEK293 cells assessed as inhibition of MCP1-induced increase in intracellular calcium levelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50337785(2-(4-((3-((R)-3-amino-4-(2,4,5-trifluorophenyl)but...)
Affinity DataIC50:  3nMAssay Description:Inhibition of human recombinant DPP4 after 60 mins by fluorescence plate readerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Yangji Chemicals

Curated by ChEMBL
LigandPNGBDBM50315023((R)-N-(2-(1-(2-(4-(2,5-difluorobenzoyl)piperazin-1...)
Affinity DataIC50:  3.70nMAssay Description:Antagonist activity at human CCR2B receptor expressed in HEK293 cells assessed as inhibition of MCP1-induced increase in intracellular calcium levelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50337779(2-(4-((3-((R)-3-amino-4-(2,4,5-trifluorophenyl)but...)
Affinity DataIC50:  6nMAssay Description:Inhibition of human recombinant DPP4 after 60 mins by fluorescence plate readerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Yangji Chemicals

Curated by ChEMBL
LigandPNGBDBM50315027((R)-N-(2-(1-(2-(1-(2-chlorobenzoyl)piperidin-4-yl)...)
Affinity DataIC50:  9nMAssay Description:Antagonist activity at CCR2 in human THP1 cells assessed as inhibition of MCP1-induced chemotaxis after 1 hr by crystal violet stainingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Yangji Chemicals

Curated by ChEMBL
LigandPNGBDBM50315020((R)-N-(2-(1-(2-(4-benzoylpiperazin-1-yl)ethyl)pyrr...)
Affinity DataIC50:  9nMAssay Description:Antagonist activity at CCR2 in human THP1 cells assessed as inhibition of MCP1-induced chemotaxis after 1 hr by crystal violet stainingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Yangji Chemicals

Curated by ChEMBL
LigandPNGBDBM50315023((R)-N-(2-(1-(2-(4-(2,5-difluorobenzoyl)piperazin-1...)
Affinity DataIC50:  10nMAssay Description:Antagonist activity at CCR2 in human THP1 cells assessed as inhibition of MCP1-induced chemotaxis after 1 hr by crystal violet stainingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50337791((R)-2-(4-(((R)-3-((R)-3-amino-4-(2,4,5-trifluoroph...)
Affinity DataIC50:  10nMAssay Description:Inhibition of human recombinant DPP4 after 60 mins by fluorescence plate readerMore data for this Ligand-Target Pair
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Yangji Chemicals

Curated by ChEMBL
LigandPNGBDBM50315026((R)-N-(2-(1-(2-(1-(2,5-difluorobenzoyl)piperidin-4...)
Affinity DataIC50:  11nMAssay Description:Antagonist activity at human CCR2B receptor expressed in HEK293 cells assessed as inhibition of MCP1-induced increase in intracellular calcium levelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Yangji Chemicals

Curated by ChEMBL
LigandPNGBDBM50315027((R)-N-(2-(1-(2-(1-(2-chlorobenzoyl)piperidin-4-yl)...)
Affinity DataIC50:  12nMAssay Description:Antagonist activity at human CCR2B receptor expressed in HEK293 cells assessed as inhibition of MCP1-induced increase in intracellular calcium levelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50337783(2-(4-((3-((R)-3-amino-4-(2,4,5-trifluorophenyl)but...)
Affinity DataIC50:  13nMAssay Description:Inhibition of human recombinant DPP4 after 60 mins by fluorescence plate readerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50337793((S)-2-(4-(((R)-3-((R)-3-amino-4-(2,4,5-trifluoroph...)
Affinity DataIC50:  13nMAssay Description:Inhibition of human recombinant DPP4 after 60 mins by fluorescence plate readerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50337788((R)-ethyl 2-(4-(((S)-3-((R)-3-amino-4-(2,4,5-trifl...)
Affinity DataIC50:  17nMAssay Description:Inhibition of human recombinant DPP4 after 60 mins by fluorescence plate readerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Yangji Chemicals

Curated by ChEMBL
LigandPNGBDBM50315020((R)-N-(2-(1-(2-(4-benzoylpiperazin-1-yl)ethyl)pyrr...)
Affinity DataIC50:  18nMAssay Description:Antagonist activity at human CCR2B receptor expressed in HEK293 cells assessed as inhibition of MCP1-induced increase in intracellular calcium levelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM11162((1R)-3-oxo-3-[3-(trifluoroethyl)-5,6-dihydro[1,2,4...)
Affinity DataIC50:  20nMAssay Description:Inhibition of human recombinant DPP4 after 60 mins by fluorescence plate readerMore data for this Ligand-Target Pair
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Yangji Chemicals

Curated by ChEMBL
LigandPNGBDBM50315021((R)-N-(2-(1-(2-(4-(2-chlorobenzoyl)piperazin-1-yl)...)
Affinity DataIC50:  23nMAssay Description:Antagonist activity at CCR2 in human THP1 cells assessed as inhibition of MCP1-induced chemotaxis after 1 hr by crystal violet stainingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Yangji Chemicals

Curated by ChEMBL
LigandPNGBDBM50315024((R)-N-(2-(1-(2-(1-benzoylpiperidin-4-yl)ethyl)pyrr...)
Affinity DataIC50:  23nMAssay Description:Antagonist activity at CCR2 in human THP1 cells assessed as inhibition of MCP1-induced chemotaxis after 1 hr by crystal violet stainingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50337790((S)-ethyl 2-(4-(((S)-3-((R)-3-amino-4-(2,4,5-trifl...)
Affinity DataIC50:  25nMAssay Description:Inhibition of human recombinant DPP4 after 60 mins by fluorescence plate readerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50337778(2-(4-((3-((R)-3-amino-4-(2,4,5-trifluorophenyl)but...)
Affinity DataIC50:  28nMAssay Description:Inhibition of human recombinant DPP4 after 60 mins by fluorescence plate readerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Yangji Chemicals

Curated by ChEMBL
LigandPNGBDBM50315025((R)-N-(2-(1-(2-(1-(2-fluorobenzoyl)piperidin-4-yl)...)
Affinity DataIC50:  29nMAssay Description:Antagonist activity at human CCR2B receptor expressed in HEK293 cells assessed as inhibition of MCP1-induced increase in intracellular calcium levelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Yangji Chemicals

Curated by ChEMBL
LigandPNGBDBM50315024((R)-N-(2-(1-(2-(1-benzoylpiperidin-4-yl)ethyl)pyrr...)
Affinity DataIC50:  30nMAssay Description:Antagonist activity at human CCR2B receptor expressed in HEK293 cells assessed as inhibition of MCP1-induced increase in intracellular calcium levelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50337768(CHEMBL1683487 | ethyl 2-(4-((3-((R)-3-amino-4-(2,4...)
Affinity DataIC50:  41nMAssay Description:Inhibition of human recombinant DPP4 after 60 mins by fluorescence plate readerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 2(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50256618((R)-3-(4-(3-amino-4-(2,4,5-trifluorophenyl)butanoy...)
Affinity DataIC50:  46.8nMAssay Description:Inhibition of DPP2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM11162((1R)-3-oxo-3-[3-(trifluoroethyl)-5,6-dihydro[1,2,4...)
Affinity DataIC50:  50nMAssay Description:Inhibition of DPP4More data for this Ligand-Target Pair
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50337786(CHEMBL1683505 | ethyl 2-(4-((3-((R)-3-amino-4-(2,4...)
Affinity DataIC50:  50nMAssay Description:Inhibition of human recombinant DPP4 after 60 mins by fluorescence plate readerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50256618((R)-3-(4-(3-amino-4-(2,4,5-trifluorophenyl)butanoy...)
Affinity DataIC50:  50nMAssay Description:Inhibition of DPP4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50206821((R)-3-amino-1-(2-benzoylpiperazin-1-yl)-4-(2,4,5-t...)
Affinity DataIC50:  50nMAssay Description:Inhibition of DPP4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50337769(2-(4-((3-((R)-3-amino-4-(2,4,5-trifluorophenyl)but...)
Affinity DataIC50:  51nMAssay Description:Inhibition of human recombinant DPP4 after 60 mins by fluorescence plate readerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50337777(2-(4-((3-((R)-3-amino-4-(2,4,5-trifluorophenyl)but...)
Affinity DataIC50:  56nMAssay Description:Inhibition of human recombinant DPP4 after 60 mins by fluorescence plate readerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50337774(CHEMBL1683493 | ethyl 5-((3-((R)-3-amino-4-(2,4,5-...)
Affinity DataIC50:  64nMAssay Description:Inhibition of human recombinant DPP4 after 60 mins by fluorescence plate readerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50337775(5-((3-((R)-3-amino-4-(2,4,5-trifluorophenyl)butano...)
Affinity DataIC50:  64nMAssay Description:Inhibition of human recombinant DPP4 after 60 mins by fluorescence plate readerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50256619((R)-5-(4-(3-amino-4-(2,4,5-trifluorophenyl)butanoy...)
Affinity DataIC50:  67nMAssay Description:Inhibition of DPP4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50337784(CHEMBL1683503 | ethyl 2-(4-((3-((R)-3-amino-4-(2,4...)
Affinity DataIC50:  68nMAssay Description:Inhibition of human recombinant DPP4 after 60 mins by fluorescence plate readerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50256266((2R)-4-(2-BENZOYL-1,2-DIAZEPAN-1-YL)-4-OXO-1-(2,4,...)
Affinity DataIC50:  70nMAssay Description:Inhibition of DPP4 (unknown origin)More data for this Ligand-Target Pair
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Yangji Chemicals

Curated by ChEMBL
LigandPNGBDBM50133112((R)-N-(2-(1-(2,4-dimethylbenzyl)pyrrolidin-3-ylami...)
Affinity DataIC50:  70nMAssay Description:Antagonist activity at CCR2 in human THP1 cells assessed as inhibition of MCP1-induced chemotaxis after 1 hr by crystal violet stainingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50206820((R)-3-amino-1-(2-benzoyl-1,2-diazepan-1-yl)-4-(2,4...)
Affinity DataIC50:  70nMAssay Description:Inhibition of DPP4More data for this Ligand-Target Pair
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50337764(3-((R)-3-amino-4-(2,4,5-trifluorophenyl)butanoyl)-...)
Affinity DataIC50:  77nMAssay Description:Inhibition of human recombinant DPP4 after 60 mins by fluorescence plate readerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50337780(CHEMBL1683499 | ethyl 2-(4-((3-((R)-3-amino-4-(2,4...)
Affinity DataIC50:  77nMAssay Description:Inhibition of human recombinant DPP4 after 60 mins by fluorescence plate readerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50337781(2-((4-((3-((R)-3-amino-4-(2,4,5-trifluorophenyl)bu...)
Affinity DataIC50:  80nMAssay Description:Inhibition of human recombinant DPP4 after 60 mins by fluorescence plate readerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50337782(CHEMBL1683501 | ethyl 2-((4-((3-((R)-3-amino-4-(2,...)
Affinity DataIC50:  80nMAssay Description:Inhibition of human recombinant DPP4 after 60 mins by fluorescence plate readerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM11162((1R)-3-oxo-3-[3-(trifluoroethyl)-5,6-dihydro[1,2,4...)
Affinity DataIC50:  87nMAssay Description:Inhibition of DPP4 (unknown origin)More data for this Ligand-Target Pair
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50337763(3-((R)-3-amino-4-(2,4,5-trifluorophenyl)butanoyl)-...)
Affinity DataIC50:  88nMAssay Description:Inhibition of human recombinant DPP4 after 60 mins by fluorescence plate readerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50337770(CHEMBL1683489 | ethyl 2-(3-((3-((R)-3-amino-4-(2,4...)
Affinity DataIC50:  95nMAssay Description:Inhibition of human recombinant DPP4 after 60 mins by fluorescence plate readerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 2(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50256619((R)-5-(4-(3-amino-4-(2,4,5-trifluorophenyl)butanoy...)
Affinity DataIC50:  99.4nMAssay Description:Inhibition of DPP2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Yangji Chemicals

Curated by ChEMBL
LigandPNGBDBM50315028((1S,3R)-N-(3,5-bis(trifluoromethyl)benzyl)-1-isopr...)
Affinity DataIC50:  100nMAssay Description:Antagonist activity at CCR2 in human THP1 cells assessed as inhibition of MCP1-induced chemotaxis after 1 hr by crystal violet stainingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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