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Found 50 with Last Name = 'lei' and Initial = 'hj'
TargetAndrogen receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50220643(6-((cyclopropylmethyl)(propyl)amino)-4-(trifluorom...)
Affinity DataIC50:  0.800nMAssay Description:Displacement of [3H]dihydrotestosterone from human androgen receptor expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50220635(6-(butyl(methyl)amino)-4-(trifluoromethyl)nicotino...)
Affinity DataIC50:  3.80nMAssay Description:Displacement of [3H]dihydrotestosterone from human androgen receptor expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50220642(6-(sec-butyl(methyl)amino)-4-(trifluoromethyl)nico...)
Affinity DataIC50:  7nMAssay Description:Displacement of [3H]dihydrotestosterone from human androgen receptor expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM25437((trifluoromethyl)benzonitrile, 14 | 4-{[(1R,2S)-2-...)
Affinity DataIC50:  12nMAssay Description:Antagonist activity at androgen receptor expressed in MDA-MB-453 cells assessed as inhibition of dihydrotestosterone-induced response in reporter gen...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50221436(4-(2-cyano-cyclohexyl-oxy)-2-trifluoromethyl-benzo...)
Affinity DataIC50:  13nMAssay Description:Antagonist activity at androgen receptor expressed in MDA-MB-453 cells assessed as inhibition of dihydrotestosterone-induced response in reporter gen...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM25428(4-[3-(4-hydroxybutyl)-4,4-dimethyl-2,5-dioxoimidaz...)
Affinity DataIC50:  15.9nMAssay Description:Displacement of [3H]dihydrotestosterone from human androgen receptor expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM25432(6-{methyl[(1R)-1-phenylethyl]amino}-4-(trifluorome...)
Affinity DataIC50:  20nMAssay Description:Displacement of [3H]dihydrotestosterone from human androgen receptor expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM25428(4-[3-(4-hydroxybutyl)-4,4-dimethyl-2,5-dioxoimidaz...)
Affinity DataIC50:  31.1nMAssay Description:Antagonist activity at human androgen receptor expressed in MDA-MB-453 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50221435(4-((trans)-2-cyanocyclohexyloxy)-2-(trifluoromethy...)
Affinity DataIC50:  43nMAssay Description:Displacement of [3H]DHT from androgen receptor expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM25432(6-{methyl[(1R)-1-phenylethyl]amino}-4-(trifluorome...)
Affinity DataIC50:  45nMAssay Description:Antagonist activity at human androgen receptor expressed in MDA-MB-453 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50221436(4-(2-cyano-cyclohexyl-oxy)-2-trifluoromethyl-benzo...)
Affinity DataIC50:  58nMAssay Description:Displacement of [3H]DHT from androgen receptor expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM25437((trifluoromethyl)benzonitrile, 14 | 4-{[(1R,2S)-2-...)
Affinity DataIC50:  60nMAssay Description:Displacement of [3H]DHT from androgen receptor expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50220640(6-(4-methylpiperidin-1-yl)-4-(trifluoromethyl)nico...)
Affinity DataIC50:  73nMAssay Description:Displacement of [3H]dihydrotestosterone from human androgen receptor expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50220644(6-(dipropylamino)-4-(trifluoromethyl)nicotinonitri...)
Affinity DataIC50:  78nMAssay Description:Displacement of [3H]dihydrotestosterone from human androgen receptor expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50220639(6-(methyl(1-phenylethyl)amino)-4-(trifluoromethyl)...)
Affinity DataIC50:  123nMAssay Description:Displacement of [3H]dihydrotestosterone from human androgen receptor expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50220640(6-(4-methylpiperidin-1-yl)-4-(trifluoromethyl)nico...)
Affinity DataIC50:  136nMAssay Description:Antagonist activity at human androgen receptor expressed in MDA-MB-453 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50220638(6-(octahydroisoquinolin-2(1H)-yl)-4-(trifluorometh...)
Affinity DataIC50:  169nMAssay Description:Displacement of [3H]dihydrotestosterone from human androgen receptor expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50221435(4-((trans)-2-cyanocyclohexyloxy)-2-(trifluoromethy...)
Affinity DataIC50:  196nMAssay Description:Antagonist activity at androgen receptor expressed in MDA-MB-453 cells assessed as inhibition of dihydrotestosterone-induced response in reporter gen...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBranched-chain-amino-acid aminotransferase, cytosolic(Rattus norvegicus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50172933(5-chloro-N'-(2-(trifluoromethyl)phenylsulfonyl)-1H...)
Affinity DataIC50:  200nMAssay Description:Inhibition of rat BCATcMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50220641(6-(piperidin-1-yl)-4-(trifluoromethyl)nicotinonitr...)
Affinity DataIC50:  209nMAssay Description:Displacement of [3H]dihydrotestosterone from human androgen receptor expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50220639(6-(methyl(1-phenylethyl)amino)-4-(trifluoromethyl)...)
Affinity DataIC50:  229nMAssay Description:Antagonist activity at human androgen receptor expressed in MDA-MB-453 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50220638(6-(octahydroisoquinolin-2(1H)-yl)-4-(trifluorometh...)
Affinity DataIC50:  260nMAssay Description:Antagonist activity at human androgen receptor expressed in MDA-MB-453 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50220641(6-(piperidin-1-yl)-4-(trifluoromethyl)nicotinonitr...)
Affinity DataIC50:  422nMAssay Description:Antagonist activity at human androgen receptor expressed in MDA-MB-453 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBranched-chain-amino-acid aminotransferase, cytosolic(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50172933(5-chloro-N'-(2-(trifluoromethyl)phenylsulfonyl)-1H...)
Affinity DataIC50:  800nMAssay Description:Inhibition of human BCATcMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50220635(6-(butyl(methyl)amino)-4-(trifluoromethyl)nicotino...)
Affinity DataIC50: >1.00E+3nMAssay Description:Antagonist activity at human androgen receptor expressed in MDA-MB-453 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50220643(6-((cyclopropylmethyl)(propyl)amino)-4-(trifluorom...)
Affinity DataIC50: >1.00E+3nMAssay Description:Antagonist activity at human androgen receptor expressed in MDA-MB-453 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50220644(6-(dipropylamino)-4-(trifluoromethyl)nicotinonitri...)
Affinity DataIC50: >1.00E+3nMAssay Description:Antagonist activity at human androgen receptor expressed in MDA-MB-453 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50220642(6-(sec-butyl(methyl)amino)-4-(trifluoromethyl)nico...)
Affinity DataIC50: >1.00E+3nMAssay Description:Antagonist activity at human androgen receptor expressed in MDA-MB-453 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBranched-chain-amino-acid aminotransferase, cytosolic(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50172943(5-chloro-N'-(o-tolylsulfonyl)-1H-indole-2-carbohyd...)
Affinity DataIC50:  1.16E+3nMAssay Description:Inhibition of human BCATcMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBranched-chain-amino-acid aminotransferase, cytosolic(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50172934(5-chloro-N'-(m-tolylsulfonyl)-1H-indole-2-carbohyd...)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of human BCATcMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50220637((S)-6-(methyl(1-phenylethyl)amino)-4-(trifluoromet...)
Affinity DataIC50:  1.70E+3nMAssay Description:Displacement of [3H]dihydrotestosterone from human androgen receptor expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBranched-chain-amino-acid aminotransferase, cytosolic(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50172945(CHEMBL205902 | N'-(phenylsulfonyl)dibenzo[b,d]fura...)
Affinity DataIC50:  2.35E+3nMAssay Description:Inhibition of human BCATcMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBranched-chain-amino-acid aminotransferase, cytosolic(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50172944(5-bromo-N'-(phenylsulfonyl)benzofuran-2-carbohydra...)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibition of human BCATcMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBranched-chain-amino-acid aminotransferase, cytosolic(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50172940(CHEMBL437702 | N'-[(3-methylphenyl)sulfonyl]dibenz...)
Affinity DataIC50:  2.80E+3nMAssay Description:Inhibition of human BCATcMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBranched-chain-amino-acid aminotransferase, mitochondrial(Rattus norvegicus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50172933(5-chloro-N'-(2-(trifluoromethyl)phenylsulfonyl)-1H...)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of rat BCATmMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBranched-chain-amino-acid aminotransferase, cytosolic(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50172931(CHEMBL205475 | N'-[(2-methylphenyl)sulfonyl]dibenz...)
Affinity DataIC50:  3.20E+3nMAssay Description:Inhibition of human BCATcMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBranched-chain-amino-acid aminotransferase, cytosolic(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50172942(5-chloro-N'-(phenylsulfonyl)benzofuran-2-carbohydr...)
Affinity DataIC50:  4.20E+3nMAssay Description:Inhibition of human BCATcMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50220636((R)-6-(1-phenylethylamino)-4-(trifluoromethyl)nico...)
Affinity DataIC50:  4.93E+3nMAssay Description:Displacement of [3H]dihydrotestosterone from human androgen receptor expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBranched-chain-amino-acid aminotransferase, cytosolic(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50172932(5-chloro-N'-(2-chlorophenylsulfonyl)-1H-indole-2-c...)
Affinity DataIC50:  5.70E+3nMAssay Description:Inhibition of human BCATcMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBranched-chain-amino-acid aminotransferase, cytosolic(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50172947(5-methoxy-N'-(phenylsulfonyl)benzofuran-2-carbohyd...)
Affinity DataIC50:  1.28E+4nMAssay Description:Inhibition of human BCATcMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBranched-chain-amino-acid aminotransferase, cytosolic(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50172930(CHEMBL379025 | N'-[(2-chlorophenyl)sulfonyl]dibenz...)
Affinity DataIC50:  1.29E+4nMAssay Description:Inhibition of human BCATcMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBranched-chain-amino-acid aminotransferase, cytosolic(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50172936(CHEMBL437697 | N'-(phenylsulfonyl)quinoline-6-carb...)
Affinity DataIC50:  1.33E+4nMAssay Description:Inhibition of human BCATcMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBranched-chain-amino-acid aminotransferase, cytosolic(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50172937(5-bromo-N'-(phenylsulfonyl)-1H-indole-2-carbohydra...)
Affinity DataIC50:  1.50E+4nMAssay Description:Inhibition of human BCATcMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBranched-chain-amino-acid aminotransferase, cytosolic(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50172929(CHEMBL205220 | N'-(phenylsulfonyl)benzofuran-2-car...)
Affinity DataIC50:  1.83E+4nMAssay Description:Inhibition of human BCATcMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBranched-chain-amino-acid aminotransferase, cytosolic(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50172928(CHEMBL382232 | N'-(phenylsulfonyl)quinoline-3-carb...)
Affinity DataIC50:  3.33E+4nMAssay Description:Inhibition of human BCATcMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBranched-chain-amino-acid aminotransferase, cytosolic(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50172941(CHEMBL205274 | N'-[(3-chlorophenyl)sulfonyl]dibenz...)
Affinity DataIC50: >3.50E+4nMAssay Description:Inhibition of human BCATcMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBranched-chain-amino-acid aminotransferase, cytosolic(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50172935(CHEMBL207686 | N'-(phenylsulfonyl)-1H-indole-2-car...)
Affinity DataIC50:  3.60E+4nMAssay Description:Inhibition of human BCATcMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBranched-chain-amino-acid aminotransferase, cytosolic(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50172946(CHEMBL205044 | N'-[(4-chlorophenyl)sulfonyl]dibenz...)
Affinity DataIC50:  3.72E+4nMAssay Description:Inhibition of human BCATcMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBranched-chain-amino-acid aminotransferase, cytosolic(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50172938(CHEMBL380652 | N'-[(4-methylphenyl)sulfonyl]dibenz...)
Affinity DataIC50:  5.10E+4nMAssay Description:Inhibition of human BCATcMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBranched-chain-amino-acid aminotransferase, cytosolic(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50172939(5-methoxy-N'-(phenylsulfonyl)-1H-indole-2-carbohyd...)
Affinity DataIC50:  5.68E+4nMAssay Description:Inhibition of human BCATcMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed