TargetAdenosylhomocysteinase(Homo sapiens (Human))
Affiliated Hospital Of Guangdong Medical University
Curated by ChEMBL
Affiliated Hospital Of Guangdong Medical University
Curated by ChEMBL
Affinity DataKi: 0.0100nMAssay Description:Inhibition of SAH hydrolase (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))
Affiliated Hospital Of Guangdong Medical University
Curated by ChEMBL
Affiliated Hospital Of Guangdong Medical University
Curated by ChEMBL
Affinity DataKi: <3nMAssay Description:Inhibition of EZH2 (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
Affinity DataKi: 145nMAssay Description:Displacement of [3H]HU243 from rat brain membrane CB1 receptor assessed as inhibition constant incubated for 90 minsMore data for this Ligand-Target Pair
Ligand Info
Affinity DataKi: 5.90E+3nMAssay Description:Binding affinity to recombinant His-tagged full length human PDI-b' x domain substrate binding pocket expressed in Escherichia coli BL21 (DE3) cells ...More data for this Ligand-Target Pair
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]CP55940 from rat brain membrane CB1 receptor assessed as inhibition constant incubated for 90 minsMore data for this Ligand-Target Pair
Affinity DataKi: 3.61E+4nMAssay Description:Binding affinity to recombinant His-tagged full length human PDI-b' x domain substrate binding pocket expressed in Escherichia coli BL21 (DE3) cells ...More data for this Ligand-Target Pair
Affinity DataKi: 5.30E+4nMAssay Description:Inhibition of human recombinant MAOAMore data for this Ligand-Target Pair
Affinity DataKi: 5.80E+4nMAssay Description:Inhibition of human recombinant MAOAMore data for this Ligand-Target Pair
Affinity DataKi: 6.30E+4nMAssay Description:Inhibition of human recombinant MAOAMore data for this Ligand-Target Pair
Affinity DataKi: 1.05E+5nMAssay Description:Inhibition of human recombinant MAOAMore data for this Ligand-Target Pair
Affinity DataKi: 1.46E+5nMAssay Description:Inhibition of human recombinant MAOAMore data for this Ligand-Target Pair
Affinity DataKi: 2.93E+5nMAssay Description:Inhibition of human recombinant MAOAMore data for this Ligand-Target Pair
Affinity DataKi: 3.09E+5nMAssay Description:Binding affinity to recombinant His-tagged full length human PDI-b' x domain substrate binding pocket expressed in Escherichia coli BL21 (DE3) cells ...More data for this Ligand-Target Pair
Affinity DataKi: 3.55E+5nMAssay Description:Inhibition of human recombinant MAOAMore data for this Ligand-Target Pair
TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))
Affiliated Hospital Of Guangdong Medical University
Curated by ChEMBL
Affiliated Hospital Of Guangdong Medical University
Curated by ChEMBL
Affinity DataIC50: 0.00970nMAssay Description:Inhibition of wild-type EZH2 (unknown origin)More data for this Ligand-Target Pair
TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))
Affiliated Hospital Of Guangdong Medical University
Curated by ChEMBL
Affiliated Hospital Of Guangdong Medical University
Curated by ChEMBL
Affinity DataIC50: 0.0100nMAssay Description:Inhibition of EZH2 (unknown origin)More data for this Ligand-Target Pair
TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))
Affiliated Hospital Of Guangdong Medical University
Curated by ChEMBL
Affiliated Hospital Of Guangdong Medical University
Curated by ChEMBL
Affinity DataIC50: 0.0280nMAssay Description:Inhibition of EZH2 (unknown origin)More data for this Ligand-Target Pair
TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))
Affiliated Hospital Of Guangdong Medical University
Curated by ChEMBL
Affiliated Hospital Of Guangdong Medical University
Curated by ChEMBL
Affinity DataIC50: 0.0380nMAssay Description:Inhibition of EZH2 (unknown origin)More data for this Ligand-Target Pair
TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))
Affiliated Hospital Of Guangdong Medical University
Curated by ChEMBL
Affiliated Hospital Of Guangdong Medical University
Curated by ChEMBL
Affinity DataIC50: 0.0390nMAssay Description:Inhibition of EZH2 (unknown origin)More data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Chinese Academy Of Medical Science And Peking Union Medical College
Curated by ChEMBL
Chinese Academy Of Medical Science And Peking Union Medical College
Curated by ChEMBL
Affinity DataIC50: 0.0530nMAssay Description:Inhibition of recombinant HIV1 protease measured assessed as hydrolysis of fluorogenic substrate by FRET assayMore data for this Ligand-Target Pair
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Chinese Academy Of Medical Science And Peking Union Medical College
Curated by ChEMBL
Chinese Academy Of Medical Science And Peking Union Medical College
Curated by ChEMBL
Affinity DataIC50: 0.0910nMAssay Description:Inhibition of HIV-1BH10 reverse transcriptase expressed in Escherichia coli assessed as polymerization by real time FRET assayMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
The People'S Hospital Of Xinjiang Uyghur Autonomous Region
Curated by ChEMBL
The People'S Hospital Of Xinjiang Uyghur Autonomous Region
Curated by ChEMBL
Affinity DataIC50: 0.100nMAssay Description:Inhibition of CDK4/Cyclin D1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 0.110nMAssay Description:Binding affinity towards alpha V/beta3 receptor by solid-phase receptor binding assays (SPRA)More data for this Ligand-Target Pair
Affinity DataIC50: 0.120nMAssay Description:Binding affinity towards alpha V-beta3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Chinese Academy Of Medical Science And Peking Union Medical College
Curated by ChEMBL
Chinese Academy Of Medical Science And Peking Union Medical College
Curated by ChEMBL
Affinity DataIC50: 0.120nMAssay Description:Inhibition of recombinant HIV1 protease measured assessed as hydrolysis of fluorogenic substrate by FRET assayMore data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Chinese Academy Of Medical Science And Peking Union Medical College
Curated by ChEMBL
Chinese Academy Of Medical Science And Peking Union Medical College
Curated by ChEMBL
Affinity DataIC50: 0.140nMAssay Description:Inhibition of recombinant HIV1 protease measured assessed as hydrolysis of fluorogenic substrate by FRET assayMore data for this Ligand-Target Pair
TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))
Affiliated Hospital Of Guangdong Medical University
Curated by ChEMBL
Affiliated Hospital Of Guangdong Medical University
Curated by ChEMBL
Affinity DataIC50: 0.153nMAssay Description:Inhibition of EZH2 Y641F mutant (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 0.160nMAssay Description:Binding affinity towards alpha V/beta3 receptor by solid-phase receptor binding assays (SPRA)More data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Chinese Academy Of Medical Science And Peking Union Medical College
Curated by ChEMBL
Chinese Academy Of Medical Science And Peking Union Medical College
Curated by ChEMBL
Affinity DataIC50: 0.160nMAssay Description:Inhibition of recombinant HIV1 protease measured assessed as hydrolysis of fluorogenic substrate by FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.200nMAssay Description:Binding affinity towards alpha V/beta3 receptor by solid-phase receptor binding assays (SPRA)More data for this Ligand-Target Pair
TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))
Affiliated Hospital Of Guangdong Medical University
Curated by ChEMBL
Affiliated Hospital Of Guangdong Medical University
Curated by ChEMBL
Affinity DataIC50: 0.210nMAssay Description:Inhibition of EZH2 Y641N mutant (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 0.270nMAssay Description:Binding affinity towards alpha V/beta3 receptor by solid-phase receptor binding assays (SPRA)More data for this Ligand-Target Pair
Affinity DataIC50: 0.310nMAssay Description:Binding affinity towards alpha V-beta1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 0.320nMAssay Description:Binding affinity towards alpha V/beta3 receptor by solid-phase receptor binding assays (SPRA)More data for this Ligand-Target Pair
TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))
Affiliated Hospital Of Guangdong Medical University
Curated by ChEMBL
Affiliated Hospital Of Guangdong Medical University
Curated by ChEMBL
Affinity DataIC50: 0.350nMAssay Description:Inhibition of EZH2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 0.350nMAssay Description:Binding affinity towards alpha V-beta1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 0.380nMAssay Description:Binding affinity towards alpha V-beta1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Chinese Academy Of Medical Science And Peking Union Medical College
Curated by ChEMBL
Chinese Academy Of Medical Science And Peking Union Medical College
Curated by ChEMBL
Affinity DataIC50: 0.400nMAssay Description:Inhibition of recombinant HIV1 protease measured assessed as hydrolysis of fluorogenic substrate by FRET assayMore data for this Ligand-Target Pair
TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))
Affiliated Hospital Of Guangdong Medical University
Curated by ChEMBL
Affiliated Hospital Of Guangdong Medical University
Curated by ChEMBL
Affinity DataIC50: 0.400nMAssay Description:Inhibition of EZH2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 0.410nMAssay Description:Binding affinity towards alpha V-beta5 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 0.430nMAssay Description:Binding affinity towards alpha V/beta3 receptor by solid-phase receptor binding assays (SPRA)More data for this Ligand-Target Pair
TargetHistone-lysine N-methyltransferase EZH1(Homo sapiens (Human))
Affiliated Hospital Of Guangdong Medical University
Curated by ChEMBL
Affiliated Hospital Of Guangdong Medical University
Curated by ChEMBL
Affinity DataIC50: 0.440nMAssay Description:Inhibition of EZH1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPurchase
Affinity DataIC50: 0.450nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of EGF-R or PDGFR-beta kinase autophosphorylation activity. The assay was performed in 96-well...More data for this Ligand-Target Pair
Affinity DataIC50: 0.450nMAssay Description:Binding affinity towards alpha V-beta5 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetCyclin-H/Cyclin-dependent kinase 7(Homo sapiens (Human))
The People'S Hospital Of Xinjiang Uyghur Autonomous Region
Curated by ChEMBL
The People'S Hospital Of Xinjiang Uyghur Autonomous Region
Curated by ChEMBL
Affinity DataIC50: 0.460nMAssay Description:Inhibition of CDK7/Cyclin H (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 0.460nMAssay Description:Binding affinity towards alpha V-beta3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetHistone-lysine N-methyltransferase EZH1(Homo sapiens (Human))
Affiliated Hospital Of Guangdong Medical University
Curated by ChEMBL
Affiliated Hospital Of Guangdong Medical University
Curated by ChEMBL
Affinity DataIC50: 0.470nMAssay Description:Inhibition of EZH1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 0.470nMAssay Description:Binding affinity towards alpha V-beta5 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))
Affiliated Hospital Of Guangdong Medical University
Curated by ChEMBL
Affiliated Hospital Of Guangdong Medical University
Curated by ChEMBL
Affinity DataIC50: 0.470nMAssay Description:Inhibition of EZH2 Y641F mutant (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 0.480nMAssay Description:Binding affinity towards alpha V-beta1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair