TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
Academia Sinica
Academia Sinica
Affinity DataKi: 7.5nMpH: 7.5Assay Description:Inhibition assay against SARS-CoV 3CL protease, a fluorometric assay was utilized to determine the inhibition constants of the samples.More data for this Ligand-Target Pair
TargetGeranylgeranyl pyrophosphate synthase BTS1(Saccharomyces cerevisiae (Yeast))
Institute Of Biological Chemistry
Curated by ChEMBL
Institute Of Biological Chemistry
Curated by ChEMBL
Affinity DataKi: 10nMAssay Description:Binding affinity to Saccharomyces cerevisiae GGPPSMore data for this Ligand-Target Pair
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
Academia Sinica
Academia Sinica
Affinity DataKi: 11.1nMpH: 7.5Assay Description:Inhibition assay against SARS-CoV 3CL protease, a fluorometric assay was utilized to determine the inhibition constants of the samples.More data for this Ligand-Target Pair
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
Academia Sinica
Academia Sinica
Affinity DataKi: 12.1nMpH: 7.5Assay Description:Inhibition assay against SARS-CoV 3CL protease, a fluorometric assay was utilized to determine the inhibition constants of the samples.More data for this Ligand-Target Pair
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
Academia Sinica
Academia Sinica
Affinity DataKi: 12.3nMpH: 7.5Assay Description:Inhibition assay against SARS-CoV 3CL protease, a fluorometric assay was utilized to determine the inhibition constants of the samples.More data for this Ligand-Target Pair
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
Academia Sinica
Academia Sinica
Affinity DataKi: 13.8nMpH: 7.5Assay Description:Inhibition assay against SARS-CoV 3CL protease, a fluorometric assay was utilized to determine the inhibition constants of the samples.More data for this Ligand-Target Pair
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
Academia Sinica
Academia Sinica
Affinity DataKi: 17.4nMpH: 7.5Assay Description:Inhibition assay against SARS-CoV 3CL protease, a fluorometric assay was utilized to determine the inhibition constants of the samples.More data for this Ligand-Target Pair
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
Academia Sinica
Academia Sinica
Affinity DataKi: 19.5nMpH: 7.5Assay Description:Inhibition assay against SARS-CoV 3CL protease, a fluorometric assay was utilized to determine the inhibition constants of the samples.More data for this Ligand-Target Pair
TargetGeranylgeranyl pyrophosphate synthase(Homo sapiens (Human))
Institute Of Biological Chemistry
Curated by ChEMBL
Institute Of Biological Chemistry
Curated by ChEMBL
Affinity DataKi: 20nMAssay Description:Binding affinity to human GGPPSMore data for this Ligand-Target Pair
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
Academia Sinica
Academia Sinica
Affinity DataKi: 22.9nMpH: 7.5Assay Description:Inhibition assay against SARS-CoV 3CL protease, a fluorometric assay was utilized to determine the inhibition constants of the samples.More data for this Ligand-Target Pair
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
Academia Sinica
Academia Sinica
Affinity DataKi: 30nM ΔG°: -42.9kJ/mole IC50: 60nMpH: 7.0 T: 2°CAssay Description:The effects of compound on enzyme activity were measured by using a fluorogenic peptide cleavage assay. Enhanced fluorescence caused by cleavage of t...More data for this Ligand-Target Pair
TargetGeranylgeranyl pyrophosphate synthase BTS1(Saccharomyces cerevisiae (Yeast))
Institute Of Biological Chemistry
Curated by ChEMBL
Institute Of Biological Chemistry
Curated by ChEMBL
Affinity DataKi: 30nMAssay Description:Binding affinity to Saccharomyces cerevisiae GGPPSMore data for this Ligand-Target Pair
TargetGeranylgeranyl pyrophosphate synthase BTS1(Saccharomyces cerevisiae (Yeast))
Institute Of Biological Chemistry
Curated by ChEMBL
Institute Of Biological Chemistry
Curated by ChEMBL
Affinity DataKi: 30nMAssay Description:Binding affinity to Saccharomyces cerevisiae GGPPSMore data for this Ligand-Target Pair
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
Academia Sinica
Academia Sinica
Affinity DataKi: 38nM ΔG°: -42.4kJ/molepH: 6.5 T: 2°CAssay Description:Peptidomimetic inhibitors against CVB3 3Cpro and SARS-CoV 3CLpro. The inhibition constant of SARS 3CLpro was analyzed with reverse-phase HPLC using a...More data for this Ligand-Target Pair
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
Academia Sinica
Academia Sinica
Affinity DataKi: 54nM ΔG°: -41.5kJ/molepH: 6.5 T: 2°CAssay Description:Peptidomimetic inhibitors against CVB3 3Cpro and SARS-CoV 3CLpro. The inhibition constant of SARS 3CLpro was analyzed with reverse-phase HPLC using a...More data for this Ligand-Target Pair
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
Academia Sinica
Academia Sinica
Affinity DataKi: 58nM ΔG°: -41.3kJ/molepH: 6.5 T: 2°CAssay Description:Peptidomimetic inhibitors against CVB3 3Cpro and SARS-CoV 3CLpro. The inhibition constant of SARS 3CLpro was analyzed with reverse-phase HPLC using a...More data for this Ligand-Target Pair
TargetGeranylgeranyl pyrophosphate synthase(Homo sapiens (Human))
Institute Of Biological Chemistry
Curated by ChEMBL
Institute Of Biological Chemistry
Curated by ChEMBL
Affinity DataKi: 60nMAssay Description:Binding affinity to human GGPPSMore data for this Ligand-Target Pair
TargetGeranylgeranyl pyrophosphate synthase BTS1(Saccharomyces cerevisiae (Yeast))
Institute Of Biological Chemistry
Curated by ChEMBL
Institute Of Biological Chemistry
Curated by ChEMBL
Affinity DataKi: 60nMAssay Description:Binding affinity to Saccharomyces cerevisiae GGPPSMore data for this Ligand-Target Pair
TargetGeranylgeranyl pyrophosphate synthase(Homo sapiens (Human))
Institute Of Biological Chemistry
Curated by ChEMBL
Institute Of Biological Chemistry
Curated by ChEMBL
Affinity DataKi: 70nMAssay Description:Binding affinity to human GGPPSMore data for this Ligand-Target Pair
TargetGeranylgeranyl pyrophosphate synthase BTS1(Saccharomyces cerevisiae (Yeast))
Institute Of Biological Chemistry
Curated by ChEMBL
Institute Of Biological Chemistry
Curated by ChEMBL
Affinity DataKi: 80nMAssay Description:Binding affinity to Saccharomyces cerevisiae GGPPSMore data for this Ligand-Target Pair
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
Academia Sinica
Academia Sinica
Affinity DataKi: 99nM ΔG°: -40.0kJ/molepH: 6.5 T: 2°CAssay Description:Peptidomimetic inhibitors against CVB3 3Cpro and SARS-CoV 3CLpro. The inhibition constant of SARS 3CLpro was analyzed with reverse-phase HPLC using a...More data for this Ligand-Target Pair
TargetGeranylgeranyl pyrophosphate synthase(Homo sapiens (Human))
Institute Of Biological Chemistry
Curated by ChEMBL
Institute Of Biological Chemistry
Curated by ChEMBL
Affinity DataKi: 110nMAssay Description:Binding affinity to human GGPPSMore data for this Ligand-Target Pair
TargetGeranylgeranyl pyrophosphate synthase(Homo sapiens (Human))
Institute Of Biological Chemistry
Curated by ChEMBL
Institute Of Biological Chemistry
Curated by ChEMBL
Affinity DataKi: 110nMAssay Description:Binding affinity to human GGPPSMore data for this Ligand-Target Pair
TargetGeranylgeranyl pyrophosphate synthase BTS1(Saccharomyces cerevisiae (Yeast))
Institute Of Biological Chemistry
Curated by ChEMBL
Institute Of Biological Chemistry
Curated by ChEMBL
Affinity DataKi: 110nMAssay Description:Binding affinity to Saccharomyces cerevisiae GGPPSMore data for this Ligand-Target Pair
TargetGeranylgeranyl pyrophosphate synthase BTS1(Saccharomyces cerevisiae (Yeast))
Institute Of Biological Chemistry
Curated by ChEMBL
Institute Of Biological Chemistry
Curated by ChEMBL
Affinity DataKi: 130nMAssay Description:Binding affinity to Saccharomyces cerevisiae GGPPSMore data for this Ligand-Target Pair
TargetGeranylgeranyl pyrophosphate synthase(Homo sapiens (Human))
Institute Of Biological Chemistry
Curated by ChEMBL
Institute Of Biological Chemistry
Curated by ChEMBL
Affinity DataKi: 230nMAssay Description:Binding affinity to human GGPPSMore data for this Ligand-Target Pair
TargetGeranylgeranyl pyrophosphate synthase BTS1(Saccharomyces cerevisiae (Yeast))
Institute Of Biological Chemistry
Curated by ChEMBL
Institute Of Biological Chemistry
Curated by ChEMBL
Affinity DataKi: 260nMAssay Description:Binding affinity to Saccharomyces cerevisiae GGPPSMore data for this Ligand-Target Pair
Affinity DataKi: 400nM ΔG°: -36.5kJ/molepH: 6.5 T: 2°CAssay Description:Peptidomimetic inhibitors against CVB3 3Cpro and SARS-CoV 3CLpro. The inhibition constant of SARS 3CLpro was analyzed with reverse-phase HPLC using a...More data for this Ligand-Target Pair
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
Academia Sinica
Academia Sinica
Affinity DataKi: 520nM ΔG°: -35.9kJ/mole IC50: 1.00E+3nMpH: 7.0 T: 2°CAssay Description:The effects of compound on enzyme activity were measured by using a fluorogenic peptide cleavage assay. Enhanced fluorescence caused by cleavage of t...More data for this Ligand-Target Pair
Affinity DataKi: 800nM ΔG°: -34.8kJ/molepH: 6.5 T: 2°CAssay Description:Peptidomimetic inhibitors against CVB3 3Cpro and SARS-CoV 3CLpro. The inhibition constant of SARS 3CLpro was analyzed with reverse-phase HPLC using a...More data for this Ligand-Target Pair
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
Academia Sinica
Academia Sinica
Affinity DataKi: 1.00E+3nMpH: 7.5Assay Description:Inhibition assay against SARS-CoV 3CL protease, a fluorometric assay was utilized to determine the inhibition constants of the samples.More data for this Ligand-Target Pair
Affinity DataKi: 1.50E+3nM ΔG°: -33.2kJ/molepH: 6.5 T: 2°CAssay Description:Peptidomimetic inhibitors against CVB3 3Cpro and SARS-CoV 3CLpro. The inhibition constant of SARS 3CLpro was analyzed with reverse-phase HPLC using a...More data for this Ligand-Target Pair
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
Academia Sinica
Academia Sinica
Affinity DataKi: 1.51E+3nM ΔG°: -33.2kJ/mole IC50: 6.00E+3nMpH: 7.0 T: 2°CAssay Description:The effects of compound on enzyme activity were measured by using a fluorogenic peptide cleavage assay. Enhanced fluorescence caused by cleavage of t...More data for this Ligand-Target Pair
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
Academia Sinica
Academia Sinica
Affinity DataKi: 1.61E+3nM ΔG°: -33.1kJ/mole IC50: 5.00E+3nMpH: 7.0 T: 2°CAssay Description:The effects of compound on enzyme activity were measured by using a fluorogenic peptide cleavage assay. Enhanced fluorescence caused by cleavage of t...More data for this Ligand-Target Pair
TargetGeranylgeranyl pyrophosphate synthase(Homo sapiens (Human))
Institute Of Biological Chemistry
Curated by ChEMBL
Institute Of Biological Chemistry
Curated by ChEMBL
Affinity DataKi: 1.80E+3nMAssay Description:Binding affinity to human GGPPSMore data for this Ligand-Target Pair
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
Academia Sinica
Academia Sinica
Affinity DataKi: 2.29E+3nM ΔG°: -32.2kJ/mole IC50: 5.00E+3nMpH: 7.0 T: 2°CAssay Description:The effects of compound on enzyme activity were measured by using a fluorogenic peptide cleavage assay. Enhanced fluorescence caused by cleavage of t...More data for this Ligand-Target Pair
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
Academia Sinica
Academia Sinica
Affinity DataKi: 2.48E+3nM ΔG°: -32.0kJ/mole IC50: 5.00E+3nMpH: 7.0 T: 2°CAssay Description:The effects of compound on enzyme activity were measured by using a fluorogenic peptide cleavage assay. Enhanced fluorescence caused by cleavage of t...More data for this Ligand-Target Pair
Affinity DataKi: 2.50E+3nM ΔG°: -32.0kJ/molepH: 6.5 T: 2°CAssay Description:Peptidomimetic inhibitors against CVB3 3Cpro and SARS-CoV 3CLpro. The inhibition constant of SARS 3CLpro was analyzed with reverse-phase HPLC using a...More data for this Ligand-Target Pair
TargetGeranylgeranyl pyrophosphate synthase(Homo sapiens (Human))
Institute Of Biological Chemistry
Curated by ChEMBL
Institute Of Biological Chemistry
Curated by ChEMBL
Affinity DataKi: 2.70E+3nMAssay Description:Binding affinity to human GGPPSMore data for this Ligand-Target Pair
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
Academia Sinica
Academia Sinica
Affinity DataKi: 2.90E+3nM ΔG°: -31.6kJ/mole IC50: 7.00E+3nMpH: 7.0 T: 2°CAssay Description:The effects of compound on enzyme activity were measured by using a fluorogenic peptide cleavage assay. Enhanced fluorescence caused by cleavage of t...More data for this Ligand-Target Pair
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
Academia Sinica
Academia Sinica
Affinity DataKi: 3.05E+3nM ΔG°: -31.5kJ/mole IC50: 7.00E+3nMpH: 7.0 T: 2°CAssay Description:The effects of compound on enzyme activity were measured by using a fluorogenic peptide cleavage assay. Enhanced fluorescence caused by cleavage of t...More data for this Ligand-Target Pair
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
Academia Sinica
Academia Sinica
Affinity DataKi: 3.10E+3nM ΔG°: -31.4kJ/mole IC50: 4.00E+3nMpH: 7.0 T: 2°CAssay Description:The effects of compound on enzyme activity were measured by using a fluorogenic peptide cleavage assay. Enhanced fluorescence caused by cleavage of t...More data for this Ligand-Target Pair
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
Academia Sinica
Academia Sinica
Affinity DataKi: 4.30E+3nM ΔG°: -30.6kJ/mole IC50: 5.00E+3nMpH: 7.0 T: 2°CAssay Description:The effects of compound on enzyme activity were measured by using a fluorogenic peptide cleavage assay. Enhanced fluorescence caused by cleavage of t...More data for this Ligand-Target Pair
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
Academia Sinica
Academia Sinica
Affinity DataKi: 4.50E+3nMpH: 7.5Assay Description:Inhibition assay against SARS-CoV 3CL protease, a fluorometric assay was utilized to determine the inhibition constants of the samples.More data for this Ligand-Target Pair
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
Academia Sinica
Academia Sinica
Affinity DataKi: 6.44E+3nM ΔG°: -29.6kJ/mole IC50: 1.00E+4nMpH: 7.0 T: 2°CAssay Description:The effects of compound on enzyme activity were measured by using a fluorogenic peptide cleavage assay. Enhanced fluorescence caused by cleavage of t...More data for this Ligand-Target Pair
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
Academia Sinica
Academia Sinica
Affinity DataKi: 6.70E+3nMpH: 7.5Assay Description:Inhibition assay against SARS-CoV 3CL protease, a fluorometric assay was utilized to determine the inhibition constants of the samples.More data for this Ligand-Target Pair
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
Academia Sinica
Academia Sinica
Affinity DataKi: 9.05E+3nM ΔG°: -28.8kJ/mole IC50: 1.00E+4nMpH: 7.0 T: 2°CAssay Description:The effects of compound on enzyme activity were measured by using a fluorogenic peptide cleavage assay. Enhanced fluorescence caused by cleavage of t...More data for this Ligand-Target Pair
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
Academia Sinica
Academia Sinica
Affinity DataKi: >5.00E+4nMpH: 7.5Assay Description:Inhibition assay against SARS-CoV 3CL protease, a fluorometric assay was utilized to determine the inhibition constants of the samples.More data for this Ligand-Target Pair
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
Academia Sinica
Academia Sinica
Affinity DataKi: >5.00E+4nMpH: 7.5Assay Description:Inhibition assay against SARS-CoV 3CL protease, a fluorometric assay was utilized to determine the inhibition constants of the samples.More data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:To measure the kinetic constants by radioactive assays, 0.2 μM wild-type E. coli OPPS and the wild-type or mutant S. cerevisiae GGPPS and human ...More data for this Ligand-Target Pair