Affinity DataKi: 15nMAssay Description:Displacement of [3H]8-Trifluoromethyl-3-cyclopropylmethyl-7-[(4-phenyl-1-piperidinyl)methyl]-1,2,4-triazolo[4,3-a]pyridine from mGlu2 receptor (unkno...More data for this Ligand-Target Pair
Affinity DataKi: 150nMAssay Description:Displacement of [3H]8-Trifluoromethyl-3-cyclopropylmethyl-7-[(4-phenyl-1-piperidinyl)methyl]-1,2,4-triazolo[4,3-a]pyridine from mGlu2 receptor (unkno...More data for this Ligand-Target Pair
Affinity DataKi: 180nMAssay Description:Displacement of [3H]8-Trifluoromethyl-3-cyclopropylmethyl-7-[(4-phenyl-1-piperidinyl)methyl]-1,2,4-triazolo[4,3-a]pyridine from mGlu2 receptor (unkno...More data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Binding affinity to human mGlu2R expressed in CHO cells by radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 68nMAssay Description:Displacement of [3H]19 from human mGlu2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 790nMAssay Description:Displacement of [3H]RX 821002 from human recombinant adrenergic alpha-2B receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of CYP2C9More data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of CYP2C19More data for this Ligand-Target Pair
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of CYP2C19 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of CYP2C8 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of CYP1A2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of CYP1A2More data for this Ligand-Target Pair
Affinity DataEC50: 8.51E+3nMAssay Description:Positive allosteric modulation of human mGlu2 receptor expressed in CHO cells assessed as potentiation of glutamate-induced effect incubated for 30 m...More data for this Ligand-Target Pair
Affinity DataEC50: 361nMAssay Description:Positive allosteric modulation of human mGlu2 receptor expressed in CHO cells assessed as potentiation of glutamate-induced effect incubated for 30 m...More data for this Ligand-Target Pair
Affinity DataEC50: 2.95E+3nMAssay Description:Positive allosteric modulation of human mGlu2 receptor expressed in CHO cells assessed as potentiation of glutamate-induced effect incubated for 30 m...More data for this Ligand-Target Pair
Affinity DataEC50: 1.07E+4nMAssay Description:Positive allosteric modulation of human mGlu2 receptor expressed in CHO cells assessed as potentiation of glutamate-induced effect incubated for 30 m...More data for this Ligand-Target Pair
Affinity DataEC50: 871nMAssay Description:Positive allosteric modulation of human mGlu2 receptor expressed in CHO cells assessed as potentiation of glutamate-induced effect incubated for 30 m...More data for this Ligand-Target Pair
Affinity DataEC50: 102nMAssay Description:Positive allosteric modulation of human mGlu2 receptor expressed in CHO cells assessed as potentiation of glutamate-induced effect incubated for 30 m...More data for this Ligand-Target Pair
Affinity DataEC50: 3.31E+3nMAssay Description:Positive allosteric modulation of human mGlu2 receptor expressed in CHO cells assessed as potentiation of glutamate-induced effect incubated for 30 m...More data for this Ligand-Target Pair
Affinity DataEC50: 3.16E+4nMAssay Description:Positive allosteric modulation of human mGlu2 receptor expressed in CHO cells assessed as potentiation of glutamate-induced effect incubated for 30 m...More data for this Ligand-Target Pair
Affinity DataEC50: 661nMAssay Description:Positive allosteric modulation of human mGlu2 receptor expressed in CHO cells assessed as potentiation of glutamate-induced effect incubated for 30 m...More data for this Ligand-Target Pair
Affinity DataEC50: 3.09E+3nMAssay Description:Positive allosteric modulation of human mGlu2 receptor expressed in CHO cells assessed as potentiation of glutamate-induced effect incubated for 30 m...More data for this Ligand-Target Pair
Affinity DataEC50: 4.68E+3nMAssay Description:Positive allosteric modulation of human mGlu2 receptor expressed in CHO cells assessed as potentiation of glutamate-induced effect incubated for 30 m...More data for this Ligand-Target Pair
Affinity DataEC50: 95nMAssay Description:Positive allosteric modulation of human mGlu2 receptor expressed in CHO cells assessed as potentiation of glutamate-induced effect incubated for 30 m...More data for this Ligand-Target Pair
Affinity DataEC50: 282nMAssay Description:Positive allosteric modulation of human mGlu2 receptor expressed in CHO cells assessed as potentiation of glutamate-induced effect incubated for 30 m...More data for this Ligand-Target Pair
Affinity DataEC50: 55nMAssay Description:Positive allosteric modulation of human mGlu2 receptor expressed in CHO cells assessed as potentiation of glutamate-induced effect incubated for 30 m...More data for this Ligand-Target Pair
Affinity DataEC50: 151nMAssay Description:Positive allosteric modulation of human mGlu2 receptor expressed in CHO cells assessed as potentiation of glutamate-induced effect incubated for 30 m...More data for this Ligand-Target Pair
Affinity DataEC50: 178nMAssay Description:Positive allosteric modulation of human mGlu2 receptor expressed in CHO cells assessed as potentiation of glutamate-induced effect incubated for 30 m...More data for this Ligand-Target Pair
Affinity DataEC50: 355nMAssay Description:Positive allosteric modulation of human mGlu2 receptor expressed in CHO cells assessed as potentiation of glutamate-induced effect incubated for 30 m...More data for this Ligand-Target Pair
Affinity DataEC50: 81nMAssay Description:Positive allosteric modulation of human mGlu2 receptor expressed in CHO cells assessed as potentiation of glutamate-induced effect incubated for 30 m...More data for this Ligand-Target Pair
Affinity DataEC50: 141nMAssay Description:Positive allosteric modulation of human mGlu2 receptor expressed in CHO cells assessed as potentiation of glutamate-induced effect incubated for 30 m...More data for this Ligand-Target Pair
Affinity DataEC50: 89nMAssay Description:Positive allosteric modulation of human mGlu2 receptor expressed in CHO cells assessed as potentiation of glutamate-induced effect incubated for 30 m...More data for this Ligand-Target Pair
Affinity DataEC50: 49nMAssay Description:Positive allosteric modulation of human mGlu2 receptor expressed in CHO cells assessed as potentiation of glutamate-induced effect incubated for 30 m...More data for this Ligand-Target Pair
Affinity DataEC50: 48nMAssay Description:Positive allosteric modulation of human mGlu2 receptor expressed in CHO cells assessed as potentiation of glutamate-induced effect incubated for 30 m...More data for this Ligand-Target Pair
Affinity DataEC50: 46nMAssay Description:Positive allosteric modulation of human mGlu2 receptor expressed in CHO cells assessed as potentiation of glutamate-induced effect incubated for 30 m...More data for this Ligand-Target Pair
Affinity DataEC50: 35nMAssay Description:Positive allosteric modulation of human mGlu2 receptor expressed in CHO cells assessed as potentiation of glutamate-induced effect incubated for 30 m...More data for this Ligand-Target Pair
Affinity DataEC50: 98nMAssay Description:Positive allosteric modulation of human mGlu2 receptor expressed in CHO cells assessed as potentiation of glutamate-induced effect incubated for 30 m...More data for this Ligand-Target Pair
Affinity DataEC50: 68nMAssay Description:Positive allosteric modulation of human mGlu2 receptor expressed in CHO cells assessed as potentiation of glutamate-induced effect incubated for 30 m...More data for this Ligand-Target Pair
Affinity DataEC50: 31nMAssay Description:Positive allosteric modulation of human mGlu2 receptor expressed in CHO cells assessed as potentiation of glutamate-induced effect incubated for 30 m...More data for this Ligand-Target Pair
Affinity DataEC50: 151nMAssay Description:Positive allosteric modulation of human mGlu2 receptor expressed in CHO cells assessed as potentiation of glutamate-induced effect incubated for 30 m...More data for this Ligand-Target Pair
Affinity DataEC50: 170nMAssay Description:Positive allosteric modulation of human mGlu2 receptor expressed in CHO cells assessed as potentiation of glutamate-induced effect incubated for 30 m...More data for this Ligand-Target Pair
Affinity DataEC50: 251nMAssay Description:Positive allosteric modulation of human mGlu2 receptor expressed in CHO cells assessed as potentiation of glutamate-induced effect incubated for 30 m...More data for this Ligand-Target Pair
Affinity DataEC50: 195nMAssay Description:Positive allosteric modulation of human mGlu2 receptor expressed in CHO cells assessed as potentiation of glutamate-induced effect incubated for 30 m...More data for this Ligand-Target Pair
Affinity DataEC50: 147nMAssay Description:Positive allosteric modulation of human mGlu2 receptor expressed in CHO cells assessed as potentiation of glutamate-induced effect incubated for 30 m...More data for this Ligand-Target Pair
Affinity DataEC50: 8.51E+3nMAssay Description:Positive allosteric modulation of human mGlu2 receptor expressed in CHO cells assessed as glutamate-induced [35S]GTPgammaS binding after 30 mins by l...More data for this Ligand-Target Pair