Affinity DataKi: 200nM IC50: 250nMAssay Description:The affinity of the compound A was evaluated in vitro on 8 cloned human serotoninergic receptors by measuring the specific binding of the ligands to ...More data for this Ligand-Target Pair
Affinity DataKi: 620nM IC50: 1.00E+3nMAssay Description:The affinity of the compound A was evaluated in vitro on 8 cloned human serotoninergic receptors by measuring the specific binding of the ligands to ...More data for this Ligand-Target Pair
Affinity DataKi: 720nM IC50: 1.40E+3nMAssay Description:The affinity of the compound A was evaluated in vitro on 8 cloned human serotoninergic receptors by measuring the specific binding of the ligands to ...More data for this Ligand-Target Pair
Affinity DataKi: 980nM IC50: 1.00E+3nMAssay Description:The affinity of the compound A was evaluated in vitro on 8 cloned human serotoninergic receptors by measuring the specific binding of the ligands to ...More data for this Ligand-Target Pair
TargetIsoform 5-HT4(E) of 5-hydroxytryptamine receptor 4 (H5-HT4(g))(Homo sapiens (Human))
Ixaltis
US Patent
Ixaltis
US Patent
Affinity DataKi: 1.60E+3nM IC50: 4.70E+3nMAssay Description:The affinity of the compound A was evaluated in vitro on 8 cloned human serotoninergic receptors by measuring the specific binding of the ligands to ...More data for this Ligand-Target Pair
Affinity DataKi: 2.60E+3nM IC50: 7.20E+3nMAssay Description:The affinity of the compound A was evaluated in vitro on 8 cloned human serotoninergic receptors by measuring the specific binding of the ligands to ...More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily KQT member 2/3(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataEC50: 200nMAssay Description:Activation of human Kv7.2/7.3 by patch clamp methodMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily KQT member 4(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataEC50: 4.00E+3nMAssay Description:Activation of human Kv7.4 by patch clamp methodMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily KQT member 4(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataEC50: >1.00E+4nMAssay Description:Activation of human Kv7.4 by patch clamp methodMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily KQT member 4(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataEC50: 1.60E+3nMAssay Description:Activation of human Kv7.4 by patch clamp methodMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily KQT member 4(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataEC50: >1.00E+4nMAssay Description:Activation of human Kv7.4 by patch clamp methodMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily KQT member 2/3(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataEC50: 460nMAssay Description:Activation of human Kv7.2/7.3 by patch clamp methodMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily KQT member 4(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataEC50: 20nMAssay Description:Activation of human Kv7.4 by patch clamp methodMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily KQT member 4(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataEC50: 100nMAssay Description:Activation of human Kv7.4 by patch clamp methodMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily KQT member 3/5(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataEC50: 200nMAssay Description:Activation of human Kv7.3/7.5 by patch clamp methodMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily KQT member 3/5(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataEC50: 360nMAssay Description:Activation of human Kv7.3/7.5 by patch clamp methodMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily KQT member 2/3(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataEC50: 40nMAssay Description:Activation of human Kv7.2/7.3 by patch clamp methodMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily KQT member 2/3(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataEC50: 80nMAssay Description:Activation of human Kv7.2/7.3 by patch clamp methodMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily KQT member 2/3(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataEC50: 20nMAssay Description:Activation of human Kv7.2/7.3 by patch clamp methodMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily KQT member 3/5(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataEC50: 80nMAssay Description:Activation of human Kv7.3/7.5 by patch clamp methodMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily KQT member 4(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataEC50: 160nMAssay Description:Activation of human Kv7.4 by patch clamp methodMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily KQT member 2/3(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataEC50: 250nMAssay Description:Activation of human Kv7.2/7.3 by patch clamp methodMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily KQT member 3/5(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataEC50: 400nMAssay Description:Activation of human Kv7.3/7.5 by patch clamp methodMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily KQT member 3/5(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataEC50: 250nMAssay Description:Activation of human Kv7.3/7.5 by patch clamp methodMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily KQT member 3/5(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataEC50: >1.00E+4nMAssay Description:Activation of human Kv7.3/7.5 by patch clamp methodMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily KQT member 3/5(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataEC50: 500nMAssay Description:Activation of human Kv7.3/7.5 by patch clamp methodMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily KQT member 2/3(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataEC50: 160nMAssay Description:Activation of human Kv7.2/7.3 by patch clamp methodMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily KQT member 2/3(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataEC50: 1.30E+3nMAssay Description:Activation of human Kv7.2/7.3 by patch clamp methodMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily KQT member 2/3(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataEC50: 130nMAssay Description:Activation of human Kv7.2/7.3 by patch clamp methodMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily KQT member 2/3(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataEC50: 200nMAssay Description:Activation of human Kv7.2/7.3 by patch clamp methodMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily KQT member 2/3(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataEC50: 40nMAssay Description:Activation of human Kv7.2/7.3 by patch clamp methodMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily KQT member 2/3(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataEC50: 100nMAssay Description:Activation of human Kv7.2/7.3 by patch clamp methodMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily KQT member 2/3(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataEC50: 50nMAssay Description:Activation of human Kv7.2/7.3 by patch clamp methodMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily KQT member 2/3(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataEC50: 80nMAssay Description:Activation of human Kv7.2/7.3 by patch clamp methodMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily KQT member 2/3(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataEC50: 790nMAssay Description:Activation of human Kv7.2/7.3 by patch clamp methodMore data for this Ligand-Target Pair