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Found 150 with Last Name = 'loiseau' and Initial = 'pm'
TargetTrypanothione reductase(Trypanosoma brucei brucei)TBA
LigandPNGBDBM50096500(CHEMBL86281 | N,N'-Bis-(3-phenyl-propyl)-N,N'-bis-...)
Affinity DataKi:  600nMAssay Description:Inhibition of Trypanosoma brucei TryR assessed as inhibition constantMore data for this Ligand-Target Pair
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TargetTrypanothione reductase(Crithidia fasciculata)TBA
LigandPNGBDBM50240622(3-(3,4-Dihydroxy-phenyl)-N-[3-(4-{3-[3-(3,4-dihydr...)
Affinity DataKi:  1.80E+3nMAssay Description:Inhibition of Crithidia fasciculata TryR overexpressed in escherichia coli assessed as inhibition constantMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetTrypanothione reductase(Trypanosoma cruzi)TBA
LigandPNGBDBM50615394(CHEMBL5266592)
Affinity DataKi:  2.00E+3nMAssay Description:Inhibition of Trypanosoma cruzi TryR assessed as inhibition constantMore data for this Ligand-Target Pair
Ligand Info
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TargetTrypanothione reductase(Trypanosoma brucei brucei)TBA
LigandPNGBDBM50096496(CHEMBL62048 | N,N'-Bis-(3-amino-propyl)-N,N'-bis-(...)
Affinity DataKi:  3.00E+3nMAssay Description:Inhibition of Trypanosoma brucei TryR assessed as inhibition constantMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetTrypanothione reductase(Trypanosoma cruzi)TBA
LigandPNGBDBM50096493(CHEMBL82641 | N,N'-Bis-(3-phenyl-propyl)-N-[3-(3-p...)
Affinity DataKi:  3.50E+3nMAssay Description:Inhibition of Trypanosoma cruzi TryR assessed as inhibition constantMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetTrypanothione reductase(Trypanosoma cruzi)TBA
LigandPNGBDBM50408797(CHEMBL151228)
Affinity DataKi:  5.50E+3nMAssay Description:Inhibition of Trypanosoma cruzi TryR assessed as inhibition constantMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetTrypanothione reductase(Trypanosoma brucei brucei)TBA
LigandPNGBDBM50462235(CHEMBL4244566)
Affinity DataKi:  7.50E+3nMAssay Description:Mixed-type inhibition of Trypanosoma brucei trypanothione reductase assessed as enzyme-inhibitor complex using varying levels of TS2 as substrate in ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTrypanothione reductase(Trypanosoma brucei brucei)TBA
LigandPNGBDBM50096498(CHEMBL86096 | N,N'-Bis-[3-(3-phenyl-propylamino)-p...)
Affinity DataKi:  1.20E+4nMAssay Description:Inhibition of Trypanosoma brucei TryR assessed as inhibition constantMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetTrypanothione reductase(Trypanosoma cruzi)TBA
LigandPNGBDBM50615395(CHEMBL5280891)
Affinity DataKi:  1.59E+4nMAssay Description:Inhibition of Trypanosoma cruzi TryR assessed as inhibition constantMore data for this Ligand-Target Pair
Ligand Info
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TargetTrypanothione reductase(Trypanosoma brucei brucei)TBA
LigandPNGBDBM50009371(1, 12-DB-3-4-3 | CHEMBL81614 | N,N'-Bis-(3-benzyla...)
Affinity DataKi:  1.90E+4nMAssay Description:Inhibition of Trypanosoma brucei TryR assessed as inhibition constantMore data for this Ligand-Target Pair
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TargetTrypanothione reductase(Trypanosoma cruzi)TBA
LigandPNGBDBM50015214(6-chloro-2-methoxy-9-acridinyl(4-diethylamino-1-me...)
Affinity DataKi:  1.90E+4nMAssay Description:Inhibition of Trypanosoma cruzi TryR assessed as inhibition constantMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetTrypanothione reductase(Trypanosoma brucei brucei)TBA
LigandPNGBDBM50462235(CHEMBL4244566)
Affinity DataKi:  2.00E+4nMAssay Description:Mixed-type inhibition of Trypanosoma brucei trypanothione reductase assessed as enzyme-inhibitor-substrate complex using varying levels of TS2 as sub...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTrypanothione reductase(Trypanosoma cruzi)TBA
LigandPNGBDBM50615396(CHEMBL311566)
Affinity DataKi:  2.70E+4nMAssay Description:Inhibition of Trypanosoma cruzi TryR assessed as inhibition constantMore data for this Ligand-Target Pair
Ligand Info
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TargetTrypanothione reductase(Trypanosoma cruzi)TBA
LigandPNGBDBM50096497(CHEMBL85779 | N-(3-Amino-propyl)-N'-[3-(3-phenyl-p...)
Affinity DataKi:  3.70E+4nMAssay Description:Inhibition of Trypanosoma cruzi TryR assessed as inhibition constantMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetTrypanothione reductase(Crithidia fasciculata)TBA
LigandPNGBDBM50615384(CHEMBL80264)
Affinity DataKi:  8.50E+4nMAssay Description:Inhibition of Crithidia fasciculata TryR overexpressed in escherichia coli assessed as inhibition constantMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetTrypanothione reductase(Trypanosoma cruzi)TBA
LigandPNGBDBM50615399(CHEMBL82315)
Affinity DataKi:  8.60E+4nMAssay Description:Inhibition of Trypanosoma cruzi TryR assessed as inhibition constant by TR assayMore data for this Ligand-Target Pair
Ligand Info
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TargetTrypanothione reductase(Trypanosoma cruzi)TBA
LigandPNGBDBM50615398(CHEMBL77450)
Affinity DataKi:  9.00E+4nMAssay Description:Inhibition of Trypanosoma cruzi TryR assessed as inhibition constant by TR assayMore data for this Ligand-Target Pair
Ligand Info
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TargetTrypanothione reductase(Trypanosoma brucei brucei)TBA
LigandPNGBDBM50615382(CHEMBL211029)
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of Trypanosoma brucei TryR assessed as inhibition constantMore data for this Ligand-Target Pair
Ligand Info
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TargetTrypanothione reductase(Trypanosoma cruzi)TBA
LigandPNGBDBM50184783(CHEMBL298628 | N*1*-(3-Amino-propyl)-N*1*-naphthal...)
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of Trypanosoma cruzi TryR assessed as inhibition constantMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetTrypanothione reductase(Trypanosoma cruzi)TBA
LigandPNGBDBM50615397(CHEMBL210576)
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of Trypanosoma cruzi TryR assessed as inhibition constantMore data for this Ligand-Target Pair
Ligand Info
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TargetTrypanothione reductase(Trypanosoma cruzi)TBA
LigandPNGBDBM50184788((4-Amino-butyl)-(3-amino-propyl)-carbamic acid ben...)
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of Trypanosoma cruzi TryR assessed as inhibition constantMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetTrypanothione reductase(Trypanosoma cruzi)TBA
LigandPNGBDBM50615392(CHEMBL2009956)
Affinity DataKi: >2.00E+6nMAssay Description:Inhibition of Trypanosoma cruzi TryR assessed as inhibition constant in presence of NADPHMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetTrypanothione reductase(Trypanosoma cruzi)TBA
LigandPNGBDBM50615391(CHEMBL5277812)
Affinity DataKi: >2.00E+6nMAssay Description:Inhibition of Trypanosoma cruzi TryR assessed as inhibition constant in presence of NADPHMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetTrypanothione reductase(Trypanosoma cruzi)TBA
LigandPNGBDBM50615390(CHEMBL210734)
Affinity DataKi: >2.00E+6nMAssay Description:Inhibition of Trypanosoma cruzi TryR assessed as inhibition constant in presence of NADPHMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetTrypanothione reductase(Trypanosoma cruzi)TBA
LigandPNGBDBM50615393(CHEMBL2008816)
Affinity DataKi: >2.00E+6nMAssay Description:Inhibition of Trypanosoma cruzi TryR assessed as inhibition constant in presence of NADPHMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
LigandPNGBDBM50139469(CHEMBL3763335)
Affinity DataIC50:  10nMAssay Description:Inhibition of human recombinant farnesyltransferase using farnesyl pyrophosphate and Dansyl-GCVLS peptide after 15 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50139637(CHEMBL3765675)
Affinity DataIC50:  13nMAssay Description:Inhibition of human recombinant farnesyltransferase using farnesyl pyrophosphate and Dansyl-GCVLS peptide after 15 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypanothione synthetase(Crithidia fasciculata)TBA
LigandPNGBDBM50615400(CHEMBL4092938)
Affinity DataIC50:  30nMAssay Description:Inhibition of Crithidia fasciculata His tagged TryS in presence of ATP by LDH/PK assayMore data for this Ligand-Target Pair
Ligand Info
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TargetDual specificity protein kinase CLK1(Mus musculus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50568546(CHEMBL4853288)
Affinity DataIC50:  35nMAssay Description:Inhibition of recombinant mouse CLK1 expressed in bacteria using GRSRSRSRSRSR as substrate in presence of [gamma-33P]ATP by radiometric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50139457(CHEMBL3765006)
Affinity DataIC50:  130nMAssay Description:Inhibition of human recombinant farnesyltransferase using farnesyl pyrophosphate and Dansyl-GCVLS peptide after 15 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50139466(CHEMBL3765154)
Affinity DataIC50:  150nMAssay Description:Inhibition of human recombinant farnesyltransferase using farnesyl pyrophosphate and Dansyl-GCVLS peptide after 15 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCasein kinase I isoform epsilon(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50568544(CHEMBL4870529)
Affinity DataIC50:  160nMAssay Description:Inhibition of recombinant human CK1 epsilon expressed in baculovirus infected Sf9 cells using RRKHAAIGSpAYSITA as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDual specificity protein kinase CLK1(Mus musculus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50568545(CHEMBL4877608)
Affinity DataIC50:  160nMAssay Description:Inhibition of recombinant mouse CLK1 expressed in bacteria using GRSRSRSRSRSR as substrate in presence of [gamma-33P]ATP by radiometric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCasein kinase I isoform epsilon(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50568545(CHEMBL4877608)
Affinity DataIC50:  180nMAssay Description:Inhibition of recombinant human CK1 epsilon expressed in baculovirus infected Sf9 cells using RRKHAAIGSpAYSITA as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50139468(CHEMBL3763857)
Affinity DataIC50:  190nMAssay Description:Inhibition of human recombinant farnesyltransferase using farnesyl pyrophosphate and Dansyl-GCVLS peptide after 15 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypanothione reductase(Trypanosoma cruzi)TBA
LigandPNGBDBM50615386(CHEMBL5283195)
Affinity DataIC50:  200nMAssay Description:Inhibition of Trypanosoma cruzi TryRMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetCasein kinase I isoform epsilon(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50568546(CHEMBL4853288)
Affinity DataIC50:  200nMAssay Description:Inhibition of recombinant human CK1 epsilon expressed in baculovirus infected Sf9 cells using RRKHAAIGSpAYSITA as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDual specificity protein kinase CLK1(Mus musculus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50568544(CHEMBL4870529)
Affinity DataIC50:  250nMAssay Description:Inhibition of recombinant mouse CLK1 expressed in bacteria using GRSRSRSRSRSR as substrate in presence of [gamma-33P]ATP by radiometric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50139472(CHEMBL3763746)
Affinity DataIC50:  290nMAssay Description:Inhibition of human recombinant farnesyltransferase using farnesyl pyrophosphate and Dansyl-GCVLS peptide after 15 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50139477(CHEMBL3765776)
Affinity DataIC50:  330nMAssay Description:Inhibition of human recombinant farnesyltransferase using farnesyl pyrophosphate and Dansyl-GCVLS peptide after 15 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50139458(CHEMBL3764994)
Affinity DataIC50:  370nMAssay Description:Inhibition of human recombinant farnesyltransferase using farnesyl pyrophosphate and Dansyl-GCVLS peptide after 15 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50139478(CHEMBL3764593)
Affinity DataIC50:  380nMAssay Description:Inhibition of human recombinant farnesyltransferase using farnesyl pyrophosphate and Dansyl-GCVLS peptide after 15 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-T1/Cyclin-dependent kinase 9(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50568546(CHEMBL4853288)
Affinity DataIC50:  500nMAssay Description:Inhibition of human recombinant CDK9/CyclinT expressed in baculovirus infected Sf9 cells using YSPTSPSYSPTSPSYSPTSPSKKK as substrate in presence of [...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTrypanothione reductase(Trypanosoma cruzi)TBA
LigandPNGBDBM50070270(CHEMBL279374 | Pentanedioic acid bis-[(3-{4-bromo-...)
Affinity DataIC50:  550nMAssay Description:Inhibition of Trypanosoma cruzi TryRMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetDual specificity protein kinase CLK1(Mus musculus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50568541(CHEMBL4860872)
Affinity DataIC50:  590nMAssay Description:Inhibition of recombinant mouse CLK1 expressed in bacteria using GRSRSRSRSRSR as substrate in presence of [gamma-33P]ATP by radiometric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTrypanothione reductase(Trypanosoma cruzi)TBA
LigandPNGBDBM50615388(CHEMBL5280255)
Affinity DataIC50:  600nMAssay Description:Inhibition of Trypanosoma cruzi TryRMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
LigandPNGBDBM50139473(CHEMBL3763689)
Affinity DataIC50:  640nMAssay Description:Inhibition of human recombinant farnesyltransferase using farnesyl pyrophosphate and Dansyl-GCVLS peptide after 15 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50139474(CHEMBL3765605)
Affinity DataIC50:  680nMAssay Description:Inhibition of human recombinant farnesyltransferase using farnesyl pyrophosphate and Dansyl-GCVLS peptide after 15 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypanothione reductase(Trypanosoma brucei brucei)TBA
LigandPNGBDBM50615401(CHEMBL5081809)
Affinity DataIC50:  750nMAssay Description:Inhibition of Trypanosoma brucei TryRMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetTrypanothione reductase(Trypanosoma cruzi)TBA
LigandPNGBDBM50615389(CHEMBL5283514)
Affinity DataIC50:  800nMAssay Description:Inhibition of Trypanosoma cruzi TryRMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
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