Affinity DataKi: 0.100nMAssay Description:Inhibition of bovine beta-trypsin type-3 using L-BAPNA as substrate preincubated for 5 mins followed by substrate addition measured over 60 minsMore data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Inhibition of bovine beta-trypsin using N-t-Boc Gln-Ala-Arg-AMC as substrate preincubated with enzyme followed by substrate addition by Dixon plot an...More data for this Ligand-Target Pair
Affinity DataKi: 2.40nMAssay Description:Inhibition of bovine beta-trypsin using BAPNA as substrate preincubated for 15 mins followed by substrate addition measured over 60 mins by Dixon plo...More data for this Ligand-Target Pair
Affinity DataKi: 5.10nMAssay Description:Inhibition of bovine beta-trypsin using BAPNA as substrate preincubated for 15 mins followed by substrate addition measured over 60 mins by Dixon plo...More data for this Ligand-Target Pair
Affinity DataKi: 13nMAssay Description:Inhibition of bovine beta-trypsinMore data for this Ligand-Target Pair
Affinity DataKi: 800nMAssay Description:Competitive inhibition of Yersinia enterocolitica Irp9 using chorismate as substrateMore data for this Ligand-Target Pair
TargetBifunctional chorismate mutase/prephenate dehydratase(Escherichia coli (strain K12))
University Of Kansas
Curated by ChEMBL
University Of Kansas
Curated by ChEMBL
Affinity DataKi: 3.00E+4nMAssay Description:Competitive inhibition of Escherichia coli K-12 EcCM expressed in Escherichia coli BL21 Star (DE3) pLysS using chorismate as substrateMore data for this Ligand-Target Pair
TargetBifunctional chorismate mutase/prephenate dehydratase(Escherichia coli (strain K12))
University Of Kansas
Curated by ChEMBL
University Of Kansas
Curated by ChEMBL
Affinity DataKi: 4.00E+4nMAssay Description:Competitive inhibition of Escherichia coli K-12 EcCM expressed in Escherichia coli BL21 Star (DE3) pLysS using chorismate as substrateMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
E-Nitiate Biopharmaceuticals (Hangzhou)
US Patent
E-Nitiate Biopharmaceuticals (Hangzhou)
US Patent
Affinity DataIC50: 1.15nMAssay Description:The inhibitory effect of the compounds on human PDE4B1 enzyme activity was determined by quantifying the 5′-adenosine monophosphate (5′-A...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
E-Nitiate Biopharmaceuticals (Hangzhou)
US Patent
E-Nitiate Biopharmaceuticals (Hangzhou)
US Patent
Affinity DataIC50: 1.22nMAssay Description:The inhibitory effect of the compounds on human PDE4B1 enzyme activity was determined by quantifying the 5′-adenosine monophosphate (5′-A...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
E-Nitiate Biopharmaceuticals (Hangzhou)
US Patent
E-Nitiate Biopharmaceuticals (Hangzhou)
US Patent
Affinity DataIC50: 1.5nMAssay Description:The inhibitory effect of the compounds on human PDE4B1 enzyme activity was determined by quantifying the 5′-adenosine monophosphate (5′-A...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
E-Nitiate Biopharmaceuticals (Hangzhou)
US Patent
E-Nitiate Biopharmaceuticals (Hangzhou)
US Patent
Affinity DataIC50: 1.60nMAssay Description:The inhibitory effect of the compounds on human PDE4B1 enzyme activity was determined by quantifying the 5′-adenosine monophosphate (5′-A...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
E-Nitiate Biopharmaceuticals (Hangzhou)
US Patent
E-Nitiate Biopharmaceuticals (Hangzhou)
US Patent
Affinity DataIC50: 2.40nMAssay Description:The inhibitory effect of the compounds on human PDE4B1 enzyme activity was determined by quantifying the 5′-adenosine monophosphate (5′-A...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
E-Nitiate Biopharmaceuticals (Hangzhou)
US Patent
E-Nitiate Biopharmaceuticals (Hangzhou)
US Patent
Affinity DataIC50: 2.70nMAssay Description:The inhibitory effect of the compounds on human PDE4B1 enzyme activity was determined by quantifying the 5′-adenosine monophosphate (5′-A...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
E-Nitiate Biopharmaceuticals (Hangzhou)
US Patent
E-Nitiate Biopharmaceuticals (Hangzhou)
US Patent
Affinity DataIC50: 2.80nMAssay Description:The inhibitory effect of the compounds on human PDE4B1 enzyme activity was determined by quantifying the 5′-adenosine monophosphate (5′-A...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
E-Nitiate Biopharmaceuticals (Hangzhou)
US Patent
E-Nitiate Biopharmaceuticals (Hangzhou)
US Patent
Affinity DataIC50: 2.90nMAssay Description:The inhibitory effect of the compounds on human PDE4B1 enzyme activity was determined by quantifying the 5′-adenosine monophosphate (5′-A...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
E-Nitiate Biopharmaceuticals (Hangzhou)
US Patent
E-Nitiate Biopharmaceuticals (Hangzhou)
US Patent
Affinity DataIC50: 3nMAssay Description:The inhibitory effect of the compounds on human PDE4B1 enzyme activity was determined by quantifying the 5′-adenosine monophosphate (5′-A...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
E-Nitiate Biopharmaceuticals (Hangzhou)
US Patent
E-Nitiate Biopharmaceuticals (Hangzhou)
US Patent
Affinity DataIC50: 3.70nMAssay Description:The inhibitory effect of the compounds on human PDE4B1 enzyme activity was determined by quantifying the 5′-adenosine monophosphate (5′-A...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
E-Nitiate Biopharmaceuticals (Hangzhou)
US Patent
E-Nitiate Biopharmaceuticals (Hangzhou)
US Patent
Affinity DataIC50: 3.80nMAssay Description:The inhibitory effect of the compounds on human PDE4B1 enzyme activity was determined by quantifying the 5′-adenosine monophosphate (5′-A...More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Chinese Academy Of Sciences
Curated by ChEMBL
Chinese Academy Of Sciences
Curated by ChEMBL
Affinity DataIC50: 3.80nMAssay Description:Inhibition of EGFR (unknown origin) using biotinylated-PTP1B (Tyr66) as substrate incubated for 5 mins prior to substrate addition measured after 1 h...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
E-Nitiate Biopharmaceuticals (Hangzhou)
US Patent
E-Nitiate Biopharmaceuticals (Hangzhou)
US Patent
Affinity DataIC50: 3.80nMAssay Description:The inhibitory effect of the compounds on human PDE4B1 enzyme activity was determined by quantifying the 5′-adenosine monophosphate (5′-A...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
E-Nitiate Biopharmaceuticals (Hangzhou)
US Patent
E-Nitiate Biopharmaceuticals (Hangzhou)
US Patent
Affinity DataIC50: 4.5nMAssay Description:The inhibitory effect of the compounds on human PDE4B1 enzyme activity was determined by quantifying the 5′-adenosine monophosphate (5′-A...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
E-Nitiate Biopharmaceuticals (Hangzhou)
US Patent
E-Nitiate Biopharmaceuticals (Hangzhou)
US Patent
Affinity DataIC50: 4.60nMAssay Description:The inhibitory effect of the compounds on human PDE4B1 enzyme activity was determined by quantifying the 5′-adenosine monophosphate (5′-A...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
E-Nitiate Biopharmaceuticals (Hangzhou)
US Patent
E-Nitiate Biopharmaceuticals (Hangzhou)
US Patent
Affinity DataIC50: 4.60nMAssay Description:The inhibitory effect of the compounds on human PDE4B1 enzyme activity was determined by quantifying the 5′-adenosine monophosphate (5′-A...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
E-Nitiate Biopharmaceuticals (Hangzhou)
US Patent
E-Nitiate Biopharmaceuticals (Hangzhou)
US Patent
Affinity DataIC50: 4.90nMAssay Description:The inhibitory effect of the compounds on human PDE4B1 enzyme activity was determined by quantifying the 5′-adenosine monophosphate (5′-A...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
E-Nitiate Biopharmaceuticals (Hangzhou)
US Patent
E-Nitiate Biopharmaceuticals (Hangzhou)
US Patent
Affinity DataIC50: 4.90nMAssay Description:The inhibitory effect of the compounds on human PDE4B1 enzyme activity was determined by quantifying the 5′-adenosine monophosphate (5′-A...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
E-Nitiate Biopharmaceuticals (Hangzhou)
US Patent
E-Nitiate Biopharmaceuticals (Hangzhou)
US Patent
Affinity DataIC50: 5nMAssay Description:The inhibitory effect of the compounds on human PDE4B1 enzyme activity was determined by quantifying the 5′-adenosine monophosphate (5′-A...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
E-Nitiate Biopharmaceuticals (Hangzhou)
US Patent
E-Nitiate Biopharmaceuticals (Hangzhou)
US Patent
Affinity DataIC50: 5nMAssay Description:The inhibitory effect of the compounds on human PDE4B1 enzyme activity was determined by quantifying the 5′-adenosine monophosphate (5′-A...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
E-Nitiate Biopharmaceuticals (Hangzhou)
US Patent
E-Nitiate Biopharmaceuticals (Hangzhou)
US Patent
Affinity DataIC50: 5.10nMAssay Description:The inhibitory effect of the compounds on human PDE4B1 enzyme activity was determined by quantifying the 5′-adenosine monophosphate (5′-A...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
E-Nitiate Biopharmaceuticals (Hangzhou)
US Patent
E-Nitiate Biopharmaceuticals (Hangzhou)
US Patent
Affinity DataIC50: 5.5nMAssay Description:The inhibitory effect of the compounds on human PDE4B1 enzyme activity was determined by quantifying the 5′-adenosine monophosphate (5′-A...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
E-Nitiate Biopharmaceuticals (Hangzhou)
US Patent
E-Nitiate Biopharmaceuticals (Hangzhou)
US Patent
Affinity DataIC50: 5.70nMAssay Description:The inhibitory effect of the compounds on human PDE4B1 enzyme activity was determined by quantifying the 5′-adenosine monophosphate (5′-A...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
E-Nitiate Biopharmaceuticals (Hangzhou)
US Patent
E-Nitiate Biopharmaceuticals (Hangzhou)
US Patent
Affinity DataIC50: 6.20nMAssay Description:The inhibitory effect of the compounds on human PDE4B1 enzyme activity was determined by quantifying the 5′-adenosine monophosphate (5′-A...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
E-Nitiate Biopharmaceuticals (Hangzhou)
US Patent
E-Nitiate Biopharmaceuticals (Hangzhou)
US Patent
Affinity DataIC50: 6.80nMAssay Description:The inhibitory effect of the compounds on human PDE4B1 enzyme activity was determined by quantifying the 5′-adenosine monophosphate (5′-A...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
E-Nitiate Biopharmaceuticals (Hangzhou)
US Patent
E-Nitiate Biopharmaceuticals (Hangzhou)
US Patent
Affinity DataIC50: 6.90nMAssay Description:The inhibitory effect of the compounds on human PDE4B1 enzyme activity was determined by quantifying the 5′-adenosine monophosphate (5′-A...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
E-Nitiate Biopharmaceuticals (Hangzhou)
US Patent
E-Nitiate Biopharmaceuticals (Hangzhou)
US Patent
Affinity DataIC50: 7nMAssay Description:The inhibitory effect of the compounds on human PDE4B1 enzyme activity was determined by quantifying the 5′-adenosine monophosphate (5′-A...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
E-Nitiate Biopharmaceuticals (Hangzhou)
US Patent
E-Nitiate Biopharmaceuticals (Hangzhou)
US Patent
Affinity DataIC50: 7.10nMAssay Description:The inhibitory effect of the compounds on human PDE4B1 enzyme activity was determined by quantifying the 5′-adenosine monophosphate (5′-A...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
E-Nitiate Biopharmaceuticals (Hangzhou)
US Patent
E-Nitiate Biopharmaceuticals (Hangzhou)
US Patent
Affinity DataIC50: 7.5nMAssay Description:The inhibitory effect of the compounds on human PDE4B1 enzyme activity was determined by quantifying the 5′-adenosine monophosphate (5′-A...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
E-Nitiate Biopharmaceuticals (Hangzhou)
US Patent
E-Nitiate Biopharmaceuticals (Hangzhou)
US Patent
Affinity DataIC50: 8.10nMAssay Description:The inhibitory effect of the compounds on human PDE4B1 enzyme activity was determined by quantifying the 5′-adenosine monophosphate (5′-A...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
E-Nitiate Biopharmaceuticals (Hangzhou)
US Patent
E-Nitiate Biopharmaceuticals (Hangzhou)
US Patent
Affinity DataIC50: 8.20nMAssay Description:The inhibitory effect of the compounds on human PDE4B1 enzyme activity was determined by quantifying the 5′-adenosine monophosphate (5′-A...More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Chinese Academy Of Sciences
Curated by ChEMBL
Chinese Academy Of Sciences
Curated by ChEMBL
Affinity DataIC50: 9nMAssay Description:Inhibition of EGFR in human A431 cellsMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
E-Nitiate Biopharmaceuticals (Hangzhou)
US Patent
E-Nitiate Biopharmaceuticals (Hangzhou)
US Patent
Affinity DataIC50: 9.90nMAssay Description:The inhibitory effect of the compounds on human PDE4B1 enzyme activity was determined by quantifying the 5′-adenosine monophosphate (5′-A...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
E-Nitiate Biopharmaceuticals (Hangzhou)
US Patent
E-Nitiate Biopharmaceuticals (Hangzhou)
US Patent
Affinity DataIC50: 10.2nMAssay Description:The inhibitory effect of the compounds on human PDE4B1 enzyme activity was determined by quantifying the 5′-adenosine monophosphate (5′-A...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
E-Nitiate Biopharmaceuticals (Hangzhou)
US Patent
E-Nitiate Biopharmaceuticals (Hangzhou)
US Patent
Affinity DataIC50: 10.3nMAssay Description:The inhibitory effect of the compounds on human PDE4B1 enzyme activity was determined by quantifying the 5′-adenosine monophosphate (5′-A...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
E-Nitiate Biopharmaceuticals (Hangzhou)
US Patent
E-Nitiate Biopharmaceuticals (Hangzhou)
US Patent
Affinity DataIC50: 11.1nMAssay Description:The inhibitory effect of the compounds on human PDE4B1 enzyme activity was determined by quantifying the 5′-adenosine monophosphate (5′-A...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
E-Nitiate Biopharmaceuticals (Hangzhou)
US Patent
E-Nitiate Biopharmaceuticals (Hangzhou)
US Patent
Affinity DataIC50: 11.5nMAssay Description:The inhibitory effect of the compounds on human PDE4B1 enzyme activity was determined by quantifying the 5′-adenosine monophosphate (5′-A...More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Chinese Academy Of Sciences
Curated by ChEMBL
Chinese Academy Of Sciences
Curated by ChEMBL
Affinity DataIC50: 12nMAssay Description:Inhibition of EGFR (unknown origin) using biotinylated-PTP1B (Tyr66) as substrate incubated for 5 mins prior to substrate addition measured after 1 h...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
E-Nitiate Biopharmaceuticals (Hangzhou)
US Patent
E-Nitiate Biopharmaceuticals (Hangzhou)
US Patent
Affinity DataIC50: 12.5nMAssay Description:The inhibitory effect of the compounds on human PDE4B1 enzyme activity was determined by quantifying the 5′-adenosine monophosphate (5′-A...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
E-Nitiate Biopharmaceuticals (Hangzhou)
US Patent
E-Nitiate Biopharmaceuticals (Hangzhou)
US Patent
Affinity DataIC50: 12.9nMAssay Description:The inhibitory effect of the compounds on human PDE4B1 enzyme activity was determined by quantifying the 5′-adenosine monophosphate (5′-A...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
E-Nitiate Biopharmaceuticals (Hangzhou)
US Patent
E-Nitiate Biopharmaceuticals (Hangzhou)
US Patent
Affinity DataIC50: 13nMAssay Description:The inhibitory effect of the compounds on human PDE4B1 enzyme activity was determined by quantifying the 5′-adenosine monophosphate (5′-A...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
E-Nitiate Biopharmaceuticals (Hangzhou)
US Patent
E-Nitiate Biopharmaceuticals (Hangzhou)
US Patent
Affinity DataIC50: 13.9nMAssay Description:The inhibitory effect of the compounds on human PDE4B1 enzyme activity was determined by quantifying the 5′-adenosine monophosphate (5′-A...More data for this Ligand-Target Pair