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Found 330 with Last Name = 'luo' and Initial = 'q'
TargetSerine protease 1(Bos taurus (bovine))
Nanyang Technological University

Curated by ChEMBL
LigandPNGBDBM50124947(CHEMBL453539)
Affinity DataKi:  0.100nMAssay Description:Inhibition of bovine beta-trypsin type-3 using L-BAPNA as substrate preincubated for 5 mins followed by substrate addition measured over 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Bos taurus (bovine))
Nanyang Technological University

Curated by ChEMBL
LigandPNGBDBM50124947(CHEMBL453539)
Affinity DataKi:  1nMAssay Description:Inhibition of bovine beta-trypsin using N-t-Boc Gln-Ala-Arg-AMC as substrate preincubated with enzyme followed by substrate addition by Dixon plot an...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Bos taurus (bovine))
Nanyang Technological University

Curated by ChEMBL
LigandPNGBDBM50124947(CHEMBL453539)
Affinity DataKi:  2.40nMAssay Description:Inhibition of bovine beta-trypsin using BAPNA as substrate preincubated for 15 mins followed by substrate addition measured over 60 mins by Dixon plo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Bos taurus (bovine))
Nanyang Technological University

Curated by ChEMBL
LigandPNGBDBM50233907(CHEMBL4102547)
Affinity DataKi:  5.10nMAssay Description:Inhibition of bovine beta-trypsin using BAPNA as substrate preincubated for 15 mins followed by substrate addition measured over 60 mins by Dixon plo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Bos taurus (bovine))
Nanyang Technological University

Curated by ChEMBL
LigandPNGBDBM50124947(CHEMBL453539)
Affinity DataKi:  13nMAssay Description:Inhibition of bovine beta-trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSalicylate synthetase, Irp9(Yersinia enterocolitica)
University Of Kansas

Curated by ChEMBL
LigandPNGBDBM50030314(CHEMBL3343825)
Affinity DataKi:  800nMAssay Description:Competitive inhibition of Yersinia enterocolitica Irp9 using chorismate as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional chorismate mutase/prephenate dehydratase(Escherichia coli (strain K12))
University Of Kansas

Curated by ChEMBL
LigandPNGBDBM96194(5-[(2-carboxyphenyl)sulfamoyl]-2-hydroxy-benzoic a...)
Affinity DataKi:  3.00E+4nMAssay Description:Competitive inhibition of Escherichia coli K-12 EcCM expressed in Escherichia coli BL21 Star (DE3) pLysS using chorismate as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional chorismate mutase/prephenate dehydratase(Escherichia coli (strain K12))
University Of Kansas

Curated by ChEMBL
LigandPNGBDBM50030314(CHEMBL3343825)
Affinity DataKi:  4.00E+4nMAssay Description:Competitive inhibition of Escherichia coli K-12 EcCM expressed in Escherichia coli BL21 Star (DE3) pLysS using chorismate as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
E-Nitiate Biopharmaceuticals (Hangzhou)

US Patent
LigandPNGBDBM570745(US11440886, Example 81 | US11440886, Example 87)
Affinity DataIC50:  1.15nMAssay Description:The inhibitory effect of the compounds on human PDE4B1 enzyme activity was determined by quantifying the 5′-adenosine monophosphate (5′-A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
E-Nitiate Biopharmaceuticals (Hangzhou)

US Patent
LigandPNGBDBM570694(US11440886, Example 41)
Affinity DataIC50:  1.22nMAssay Description:The inhibitory effect of the compounds on human PDE4B1 enzyme activity was determined by quantifying the 5′-adenosine monophosphate (5′-A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
E-Nitiate Biopharmaceuticals (Hangzhou)

US Patent
LigandPNGBDBM570762(US11440886, Example 100 | US11440886, Example 96)
Affinity DataIC50:  1.5nMAssay Description:The inhibitory effect of the compounds on human PDE4B1 enzyme activity was determined by quantifying the 5′-adenosine monophosphate (5′-A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
E-Nitiate Biopharmaceuticals (Hangzhou)

US Patent
LigandPNGBDBM570783(US11440886, Example 114)
Affinity DataIC50:  1.60nMAssay Description:The inhibitory effect of the compounds on human PDE4B1 enzyme activity was determined by quantifying the 5′-adenosine monophosphate (5′-A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
E-Nitiate Biopharmaceuticals (Hangzhou)

US Patent
LigandPNGBDBM570762(US11440886, Example 100 | US11440886, Example 96)
Affinity DataIC50:  2.40nMAssay Description:The inhibitory effect of the compounds on human PDE4B1 enzyme activity was determined by quantifying the 5′-adenosine monophosphate (5′-A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
E-Nitiate Biopharmaceuticals (Hangzhou)

US Patent
LigandPNGBDBM570775(US11440886, Example 106)
Affinity DataIC50:  2.70nMAssay Description:The inhibitory effect of the compounds on human PDE4B1 enzyme activity was determined by quantifying the 5′-adenosine monophosphate (5′-A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
E-Nitiate Biopharmaceuticals (Hangzhou)

US Patent
LigandPNGBDBM570754(US11440886, Example 88)
Affinity DataIC50:  2.80nMAssay Description:The inhibitory effect of the compounds on human PDE4B1 enzyme activity was determined by quantifying the 5′-adenosine monophosphate (5′-A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
E-Nitiate Biopharmaceuticals (Hangzhou)

US Patent
LigandPNGBDBM570708(US11440886, Example 49)
Affinity DataIC50:  2.90nMAssay Description:The inhibitory effect of the compounds on human PDE4B1 enzyme activity was determined by quantifying the 5′-adenosine monophosphate (5′-A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
E-Nitiate Biopharmaceuticals (Hangzhou)

US Patent
LigandPNGBDBM570774(US11440886, Example 105)
Affinity DataIC50:  3nMAssay Description:The inhibitory effect of the compounds on human PDE4B1 enzyme activity was determined by quantifying the 5′-adenosine monophosphate (5′-A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
E-Nitiate Biopharmaceuticals (Hangzhou)

US Patent
LigandPNGBDBM570763(US11440886, Example 97)
Affinity DataIC50:  3.70nMAssay Description:The inhibitory effect of the compounds on human PDE4B1 enzyme activity was determined by quantifying the 5′-adenosine monophosphate (5′-A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
E-Nitiate Biopharmaceuticals (Hangzhou)

US Patent
LigandPNGBDBM570744(US11440886, Example 80 | US11440886, Example 85)
Affinity DataIC50:  3.80nMAssay Description:The inhibitory effect of the compounds on human PDE4B1 enzyme activity was determined by quantifying the 5′-adenosine monophosphate (5′-A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM4626(Anilinoquinazoline deriv. 9 | CHEMBL301018 | N-(3-...)
Affinity DataIC50:  3.80nMAssay Description:Inhibition of EGFR (unknown origin) using biotinylated-PTP1B (Tyr66) as substrate incubated for 5 mins prior to substrate addition measured after 1 h...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
E-Nitiate Biopharmaceuticals (Hangzhou)

US Patent
LigandPNGBDBM570756(US11440886, Example 90)
Affinity DataIC50:  3.80nMAssay Description:The inhibitory effect of the compounds on human PDE4B1 enzyme activity was determined by quantifying the 5′-adenosine monophosphate (5′-A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
E-Nitiate Biopharmaceuticals (Hangzhou)

US Patent
LigandPNGBDBM570652(US11440886, Example 18)
Affinity DataIC50:  4.5nMAssay Description:The inhibitory effect of the compounds on human PDE4B1 enzyme activity was determined by quantifying the 5′-adenosine monophosphate (5′-A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
E-Nitiate Biopharmaceuticals (Hangzhou)

US Patent
LigandPNGBDBM570655(US11440886, Example 21)
Affinity DataIC50:  4.60nMAssay Description:The inhibitory effect of the compounds on human PDE4B1 enzyme activity was determined by quantifying the 5′-adenosine monophosphate (5′-A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
E-Nitiate Biopharmaceuticals (Hangzhou)

US Patent
LigandPNGBDBM570653(US11440886, Example 19)
Affinity DataIC50:  4.60nMAssay Description:The inhibitory effect of the compounds on human PDE4B1 enzyme activity was determined by quantifying the 5′-adenosine monophosphate (5′-A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
E-Nitiate Biopharmaceuticals (Hangzhou)

US Patent
LigandPNGBDBM570696(US11440886, Example 43)
Affinity DataIC50:  4.90nMAssay Description:The inhibitory effect of the compounds on human PDE4B1 enzyme activity was determined by quantifying the 5′-adenosine monophosphate (5′-A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
E-Nitiate Biopharmaceuticals (Hangzhou)

US Patent
LigandPNGBDBM570646(US11440886, Example 13)
Affinity DataIC50:  4.90nMAssay Description:The inhibitory effect of the compounds on human PDE4B1 enzyme activity was determined by quantifying the 5′-adenosine monophosphate (5′-A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
E-Nitiate Biopharmaceuticals (Hangzhou)

US Patent
LigandPNGBDBM570657(US11440886, Example 23)
Affinity DataIC50:  5nMAssay Description:The inhibitory effect of the compounds on human PDE4B1 enzyme activity was determined by quantifying the 5′-adenosine monophosphate (5′-A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
E-Nitiate Biopharmaceuticals (Hangzhou)

US Patent
LigandPNGBDBM570639(US11440886, Example 5)
Affinity DataIC50:  5nMAssay Description:The inhibitory effect of the compounds on human PDE4B1 enzyme activity was determined by quantifying the 5′-adenosine monophosphate (5′-A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
E-Nitiate Biopharmaceuticals (Hangzhou)

US Patent
LigandPNGBDBM570722(US11440886, Example 59)
Affinity DataIC50:  5.10nMAssay Description:The inhibitory effect of the compounds on human PDE4B1 enzyme activity was determined by quantifying the 5′-adenosine monophosphate (5′-A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
E-Nitiate Biopharmaceuticals (Hangzhou)

US Patent
LigandPNGBDBM570721(US11440886, Example 58)
Affinity DataIC50:  5.5nMAssay Description:The inhibitory effect of the compounds on human PDE4B1 enzyme activity was determined by quantifying the 5′-adenosine monophosphate (5′-A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
E-Nitiate Biopharmaceuticals (Hangzhou)

US Patent
LigandPNGBDBM570641(US11440886, Example 7)
Affinity DataIC50:  5.70nMAssay Description:The inhibitory effect of the compounds on human PDE4B1 enzyme activity was determined by quantifying the 5′-adenosine monophosphate (5′-A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
E-Nitiate Biopharmaceuticals (Hangzhou)

US Patent
LigandPNGBDBM570725(US11440886, Example 61)
Affinity DataIC50:  6.20nMAssay Description:The inhibitory effect of the compounds on human PDE4B1 enzyme activity was determined by quantifying the 5′-adenosine monophosphate (5′-A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
E-Nitiate Biopharmaceuticals (Hangzhou)

US Patent
LigandPNGBDBM570693(US11440886, Example 40)
Affinity DataIC50:  6.80nMAssay Description:The inhibitory effect of the compounds on human PDE4B1 enzyme activity was determined by quantifying the 5′-adenosine monophosphate (5′-A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
E-Nitiate Biopharmaceuticals (Hangzhou)

US Patent
LigandPNGBDBM570755(US11440886, Example 89)
Affinity DataIC50:  6.90nMAssay Description:The inhibitory effect of the compounds on human PDE4B1 enzyme activity was determined by quantifying the 5′-adenosine monophosphate (5′-A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
E-Nitiate Biopharmaceuticals (Hangzhou)

US Patent
LigandPNGBDBM570744(US11440886, Example 80 | US11440886, Example 85)
Affinity DataIC50:  7nMAssay Description:The inhibitory effect of the compounds on human PDE4B1 enzyme activity was determined by quantifying the 5′-adenosine monophosphate (5′-A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
E-Nitiate Biopharmaceuticals (Hangzhou)

US Patent
LigandPNGBDBM570706(US11440886, Example 47)
Affinity DataIC50:  7.10nMAssay Description:The inhibitory effect of the compounds on human PDE4B1 enzyme activity was determined by quantifying the 5′-adenosine monophosphate (5′-A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
E-Nitiate Biopharmaceuticals (Hangzhou)

US Patent
LigandPNGBDBM570746(US11440886, Example 82)
Affinity DataIC50:  7.5nMAssay Description:The inhibitory effect of the compounds on human PDE4B1 enzyme activity was determined by quantifying the 5′-adenosine monophosphate (5′-A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
E-Nitiate Biopharmaceuticals (Hangzhou)

US Patent
LigandPNGBDBM570734(US11440886, Example 70)
Affinity DataIC50:  8.10nMAssay Description:The inhibitory effect of the compounds on human PDE4B1 enzyme activity was determined by quantifying the 5′-adenosine monophosphate (5′-A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
E-Nitiate Biopharmaceuticals (Hangzhou)

US Patent
LigandPNGBDBM570695(US11440886, Example 42)
Affinity DataIC50:  8.20nMAssay Description:The inhibitory effect of the compounds on human PDE4B1 enzyme activity was determined by quantifying the 5′-adenosine monophosphate (5′-A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM4626(Anilinoquinazoline deriv. 9 | CHEMBL301018 | N-(3-...)
Affinity DataIC50:  9nMAssay Description:Inhibition of EGFR in human A431 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
E-Nitiate Biopharmaceuticals (Hangzhou)

US Patent
LigandPNGBDBM570784(US11440886, Example 115)
Affinity DataIC50:  9.90nMAssay Description:The inhibitory effect of the compounds on human PDE4B1 enzyme activity was determined by quantifying the 5′-adenosine monophosphate (5′-A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
E-Nitiate Biopharmaceuticals (Hangzhou)

US Patent
LigandPNGBDBM570726(US11440886, Example 62)
Affinity DataIC50:  10.2nMAssay Description:The inhibitory effect of the compounds on human PDE4B1 enzyme activity was determined by quantifying the 5′-adenosine monophosphate (5′-A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
E-Nitiate Biopharmaceuticals (Hangzhou)

US Patent
LigandPNGBDBM570649(US11440886, Example 16)
Affinity DataIC50:  10.3nMAssay Description:The inhibitory effect of the compounds on human PDE4B1 enzyme activity was determined by quantifying the 5′-adenosine monophosphate (5′-A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
E-Nitiate Biopharmaceuticals (Hangzhou)

US Patent
LigandPNGBDBM570727(US11440886, Example 63)
Affinity DataIC50:  11.1nMAssay Description:The inhibitory effect of the compounds on human PDE4B1 enzyme activity was determined by quantifying the 5′-adenosine monophosphate (5′-A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
E-Nitiate Biopharmaceuticals (Hangzhou)

US Patent
LigandPNGBDBM570659(US11440886, Example 25)
Affinity DataIC50:  11.5nMAssay Description:The inhibitory effect of the compounds on human PDE4B1 enzyme activity was determined by quantifying the 5′-adenosine monophosphate (5′-A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50428416(CHEMBL2334002)
Affinity DataIC50:  12nMAssay Description:Inhibition of EGFR (unknown origin) using biotinylated-PTP1B (Tyr66) as substrate incubated for 5 mins prior to substrate addition measured after 1 h...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
E-Nitiate Biopharmaceuticals (Hangzhou)

US Patent
LigandPNGBDBM570765(US11440886, Example 101-2 | US11440886, Example 98...)
Affinity DataIC50:  12.5nMAssay Description:The inhibitory effect of the compounds on human PDE4B1 enzyme activity was determined by quantifying the 5′-adenosine monophosphate (5′-A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
E-Nitiate Biopharmaceuticals (Hangzhou)

US Patent
LigandPNGBDBM570759(US11440886, Example 93)
Affinity DataIC50:  12.9nMAssay Description:The inhibitory effect of the compounds on human PDE4B1 enzyme activity was determined by quantifying the 5′-adenosine monophosphate (5′-A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
E-Nitiate Biopharmaceuticals (Hangzhou)

US Patent
LigandPNGBDBM570654(US11440886, Example 20)
Affinity DataIC50:  13nMAssay Description:The inhibitory effect of the compounds on human PDE4B1 enzyme activity was determined by quantifying the 5′-adenosine monophosphate (5′-A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
E-Nitiate Biopharmaceuticals (Hangzhou)

US Patent
LigandPNGBDBM570667(US11440886, Example 32)
Affinity DataIC50:  13.9nMAssay Description:The inhibitory effect of the compounds on human PDE4B1 enzyme activity was determined by quantifying the 5′-adenosine monophosphate (5′-A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
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