Compile Data Set for Download or QSAR
maximum 50k data
Found 796 with Last Name = 'lydon' and Initial = 'n'
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50040929(4,5-dianilinophthalimide | 5,6-bis(phenylamino)-1H...)
Affinity DataKi:  160nMAssay Description:Competitive inhibition of ATP binding to EGF-RMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM3014(3-((3-Hydroxyphenyl)amino)-4-((3-chlorophenyl)amin...)
Affinity DataIC50:  1nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Novartis Pharmaceuticals

LigandPNGBDBM3023(3-{4-[(3-chlorophenyl)amino]-1H-pyrazolo[3,4-d]pyr...)
Affinity DataIC50:  2nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM3029(3-(4-Aminophenyl)-4-((3-chlorophenyl)amino)-1H-pyr...)
Affinity DataIC50:  2nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM3032(CHEMBL1204168 | CHEMBL29197 | N-(3-bromophenyl)-6,...)
Affinity DataIC50:  4nMAssay Description:In vitro inhibitory activity against epidermal growth factor receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM3016(3-((4-Aminophenyl)amino)-4-((3-chlorophenyl)amino)...)
Affinity DataIC50:  5nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM3027(3-(3-Aminophenyl)-4-((3-chlorophenyl)amino)-1H-pyr...)
Affinity DataIC50:  5nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM3032(CHEMBL1204168 | CHEMBL29197 | N-(3-bromophenyl)-6,...)
Affinity DataIC50:  6nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM3025(3-(4-Hydroxyphenyl)-4-((3-chlorophenyl)amino)pyraz...)
Affinity DataIC50:  6nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50051308((3-Chloro-phenyl)-(9H-pyrimido[4,5-b]indol-4-yl)-a...)
Affinity DataIC50:  6nMAssay Description:In vitro inhibitory activity against epidermal growth factor receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM3018(3-(Benzylamino)-4-((3-chlorophenyl)amino)-1H-pyraz...)
Affinity DataIC50:  7nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM3021(3-((4-Methoxybenzyl)amino)-4-((3-chlorophenyl)amin...)
Affinity DataIC50:  7nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM3020(3-((3-Methoxybenzyl)amino)-4-((3-chlorophenyl)amin...)
Affinity DataIC50:  8nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM3013(3-((3-Methoxyphenyl)amino)-4-((3-chlorophenyl)amin...)
Affinity DataIC50:  8nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM3012(3-((4-Hydroxyphenyl)amino)-4-((3-chlorophenyl)amin...)
Affinity DataIC50:  8nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287090(4-Chloro-N-[4-methyl-3-(4-pyridin-3-yl-pyrimidin-2...)
Affinity DataIC50:  10nMAssay Description:Inhibition of tyrosine kinase(PDGF-R)More data for this Ligand-Target Pair
In DepthDetails Article
TargetPlatelet-derived growth factor receptor alpha/beta(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50175491(4-Methyl-N-[4-methyl-3-(4-pyridin-3-yl-pyrimidin-2...)
Affinity DataIC50:  10nMAssay Description:Inhibition of tyrosine kinase(PDGF-R)More data for this Ligand-Target Pair
In DepthDetails Article
TargetPlatelet-derived growth factor receptor alpha/beta(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287090(4-Chloro-N-[4-methyl-3-(4-pyridin-3-yl-pyrimidin-2...)
Affinity DataIC50:  10nMAssay Description:Inhibition of the platelet-derived growth factor receptor.More data for this Ligand-Target Pair
In DepthDetails Article
TargetPlatelet-derived growth factor receptor alpha/beta(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50175491(4-Methyl-N-[4-methyl-3-(4-pyridin-3-yl-pyrimidin-2...)
Affinity DataIC50:  10nMAssay Description:Inhibition of the platelet-derived growth factor receptor.More data for this Ligand-Target Pair
In DepthDetails Article
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50051302((3-Chloro-phenyl)-(5-methyl-6-phenyl-7H-pyrrolo[2,...)
Affinity DataIC50:  10nMAssay Description:In vitro inhibitory activity against epidermal growth factor receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM3022(4-(Phenylamino)pyrazolo[3,4-d]pyrimidine deriv. 23...)
Affinity DataIC50:  19nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50051312((3-Bromo-phenyl)-(5,6-dimethyl-7H-pyrrolo[2,3-d]py...)
Affinity DataIC50:  25nMAssay Description:In vitro inhibitory activity against epidermal growth factor receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM3023(3-{4-[(3-chlorophenyl)amino]-1H-pyrazolo[3,4-d]pyr...)
Affinity DataIC50:  26nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM3019(3-((3-Chlorobenzyl)amino)-4-((3-chlorophenyl)amino...)
Affinity DataIC50:  26nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50051317((3-Chloro-phenyl)-(5,6-dimethyl-7H-pyrrolo[2,3-d]p...)
Affinity DataIC50:  27nMAssay Description:In vitro inhibitory activity against epidermal growth factor receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM3017(3-((4-(Dimethylamino)phenyl)amino)-4-((3-chlorophe...)
Affinity DataIC50:  29nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50051297((3-Chloro-phenyl)-(6,7,8,9-tetrahydro-5H-pyrimido[...)
Affinity DataIC50:  29nMAssay Description:In vitro inhibitory activity against epidermal growth factor receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM3011(3-((4-Methoxyphenyl)-amino)-4-((3-chlorophenyl)ami...)
Affinity DataIC50:  30nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase transforming protein Abl(Abelson murine leukemia virus)
Novartis Pharmaceuticals

LigandPNGBDBM3032(CHEMBL1204168 | CHEMBL29197 | N-(3-bromophenyl)-6,...)
Affinity DataIC50:  30nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM3008(3,4-Bis((3-chlorophenyl)amino)-1H-pyrazolo[3,4-d]p...)
Affinity DataIC50:  33nMpH: 7.5 T: 2°CAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM3026(3-(3-Nitrophenyl)-4-((3-chlorophenyl)amino)-1H-pyr...)
Affinity DataIC50:  37nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM13530(4-[(4-methylpiperazin-1-yl)methyl]-N-[4-methyl-3-[...)
Affinity DataIC50:  38nMAssay Description:Inhibition of v-Abl tyrosine kinase.More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50051306((3-Bromo-phenyl)-(6,7,8,9-tetrahydro-5H-pyrimido[4...)
Affinity DataIC50:  46nMAssay Description:In vitro inhibitory activity against epidermal growth factor receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287091(CHEMBL20252 | Naphthalene-2-carboxylic acid [4-met...)
Affinity DataIC50:  50nMAssay Description:Inhibition of the platelet-derived growth factor receptor.More data for this Ligand-Target Pair
In DepthDetails Article
TargetPlatelet-derived growth factor receptor alpha/beta(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM13530(4-[(4-methylpiperazin-1-yl)methyl]-N-[4-methyl-3-[...)
Affinity DataIC50:  50nMAssay Description:Inhibition of the platelet-derived growth factor receptor.More data for this Ligand-Target Pair
In DepthDetails Article
TargetPlatelet-derived growth factor receptor alpha/beta(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287091(CHEMBL20252 | Naphthalene-2-carboxylic acid [4-met...)
Affinity DataIC50:  50nMAssay Description:Inhibition of tyrosine kinase(PDGF-R)More data for this Ligand-Target Pair
In DepthDetails Article
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50007064(2-Hydroxy-4-[4-(2-nitro-vinyl)-phenoxysulfonyl]-be...)
Affinity DataIC50:  54nMAssay Description:Inhibition of the epidermal growth factor receptor expressed in A431 cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM3006(3,4-Di-(phenylamino)-1H-pyrazolo[3,4-d]pyrimidine ...)
Affinity DataIC50:  58nMpH: 7.5 T: 2°CAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM3007(3-((3-Chlorophenyl)amino)-4-(phenylamino)-1H-pyraz...)
Affinity DataIC50:  84nMpH: 7.5 T: 2°CAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50051305((3-Chloro-phenyl)-(5,6-diphenyl-7H-pyrrolo[2,3-d]p...)
Affinity DataIC50:  96nMAssay Description:In vitro inhibitory activity against epidermal growth factor receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM3024(3-(4-Methoxyphenyl)-4-((3-chlorophenyl)amino)-1H-p...)
Affinity DataIC50:  96nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50240407(CHEMBL20926 | N-(4-methyl-3-(4-(pyridin-3-yl)pyrim...)
Affinity DataIC50:  100nMAssay Description:Inhibition of tyrosine kinase(PDGF-R)More data for this Ligand-Target Pair
In DepthDetails Article
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290422(4-(4-Methyl-piperazin-1-ylmethyl)-N-[3-(4-pyridin-...)
Affinity DataIC50:  100nMAssay Description:Inhibition of v-Abl tyrosine kinase.More data for this Ligand-Target Pair
In DepthDetails Article
TargetPlatelet-derived growth factor receptor alpha/beta(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50240407(CHEMBL20926 | N-(4-methyl-3-(4-(pyridin-3-yl)pyrim...)
Affinity DataIC50:  100nMAssay Description:Inhibition of the platelet-derived growth factor receptor.More data for this Ligand-Target Pair
In DepthDetails Article
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50051320((6,7,8,9-Tetrahydro-5H-pyrimido[4,5-b]indol-4-yl)-...)
Affinity DataIC50:  110nMAssay Description:In vitro inhibitory activity against epidermal growth factor receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50051297((3-Chloro-phenyl)-(6,7,8,9-tetrahydro-5H-pyrimido[...)
Affinity DataIC50:  120nMAssay Description:Inhibition of EGF-stimulated tyrosine phosphorylation in A431 cells expressing EGF-RMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50051308((3-Chloro-phenyl)-(9H-pyrimido[4,5-b]indol-4-yl)-a...)
Affinity DataIC50:  120nMAssay Description:Inhibition of EGF-stimulated tyrosine phosphorylation in A431 cells expressing EGF-RMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM3010(3-((3-Chlorophenyl)amino)-4-((3-methylphenyl)amino...)
Affinity DataIC50:  130nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM3009(3-((3-Chlorophenyl)amino)-4-((3-bromophenyl)amino)...)
Affinity DataIC50:  130nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase transforming protein Abl(Abelson murine leukemia virus)
Novartis Pharmaceuticals

LigandPNGBDBM3012(3-((4-Hydroxyphenyl)amino)-4-((3-chlorophenyl)amin...)
Affinity DataIC50:  150nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Displayed 1 to 50 (of 796 total ) | Next | Last >>
Jump to: