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Found 47 with Last Name = 'mackenzie' and Initial = 'sj'
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
University Of Paisley

Curated by ChEMBL
LigandPNGBDBM50236083(5-[1-(3-Cyclopentyloxy-4-methoxy-phenyl)-meth-(Z)-...)
Affinity DataIC50:  310nMAssay Description:Inhibition of PDE4BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
University Of Paisley

Curated by ChEMBL
LigandPNGBDBM50372899(CHEMBL403367)
Affinity DataIC50:  740nMAssay Description:Inhibition of PDE4BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
University Of Paisley

Curated by ChEMBL
LigandPNGBDBM50236078(5-(3-(cyclopentyloxy)-4-methoxybenzylidene)-2-thio...)
Affinity DataIC50:  890nMAssay Description:Inhibition of PDE4BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
University Of Paisley

Curated by ChEMBL
LigandPNGBDBM50372908(CHEMBL404692)
Affinity DataIC50:  1.09E+3nMAssay Description:Inhibition of PDE4BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Heriot-Watt University

Curated by ChEMBL
LigandPNGBDBM50224551(CHEMBL400572 | difluoro(4-(2-oxo-1,2-diphenylethyl...)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of PTP1B expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
University Of Paisley

Curated by ChEMBL
LigandPNGBDBM50372904(CHEMBL404723)
Affinity DataIC50:  1.85E+3nMAssay Description:Inhibition of PDE4BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
University Of Paisley

Curated by ChEMBL
LigandPNGBDBM50372913(CHEMBL402997)
Affinity DataIC50:  1.94E+3nMAssay Description:Inhibition of PDE4BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
University Of Paisley

Curated by ChEMBL
LigandPNGBDBM14361((R,S)-Rolipram | 4-(3-cyclopentyloxy-4-methoxy-phe...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of PDE4BMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
University Of Paisley

Curated by ChEMBL
LigandPNGBDBM50372900(CHEMBL257521)
Affinity DataIC50:  2.87E+3nMAssay Description:Inhibition of PDE4BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Heriot-Watt University

Curated by ChEMBL
LigandPNGBDBM50224541(2-(4-(benzyloxy)-3-(2-(2-(4-chlorophenyl)-4-methyl...)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of PTP1B in a cell-free assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
University Of Paisley

Curated by ChEMBL
LigandPNGBDBM50372911(CHEMBL255610)
Affinity DataIC50:  3.07E+3nMAssay Description:Inhibition of PDE4BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
University Of Paisley

Curated by ChEMBL
LigandPNGBDBM50372914(CHEMBL403171)
Affinity DataIC50:  3.08E+3nMAssay Description:Inhibition of PDE4BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Heriot-Watt University

Curated by ChEMBL
LigandPNGBDBM50224541(2-(4-(benzyloxy)-3-(2-(2-(4-chlorophenyl)-4-methyl...)
Affinity DataIC50:  3.20E+3nMAssay Description:Inhibition of PTP1B expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
University Of Paisley

Curated by ChEMBL
LigandPNGBDBM50372907(CHEMBL255131)
Affinity DataIC50:  4.01E+3nMAssay Description:Inhibition of PDE4BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
University Of Paisley

Curated by ChEMBL
LigandPNGBDBM50372912(CHEMBL429680)
Affinity DataIC50:  4.13E+3nMAssay Description:Inhibition of PDE4BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
University Of Paisley

Curated by ChEMBL
LigandPNGBDBM50372905(CHEMBL270636)
Affinity DataIC50:  5.30E+3nMAssay Description:Inhibition of PDE4BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
University Of Paisley

Curated by ChEMBL
LigandPNGBDBM50372902(CHEMBL270637)
Affinity DataIC50:  6.51E+3nMAssay Description:Inhibition of PDE4BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
University Of Paisley

Curated by ChEMBL
LigandPNGBDBM50372906(CHEMBL270635)
Affinity DataIC50:  6.91E+3nMAssay Description:Inhibition of PDE4BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A(Homo sapiens (Human))
University Of Paisley

Curated by ChEMBL
LigandPNGBDBM50372906(CHEMBL270635)
Affinity DataIC50:  9.46E+3nMAssay Description:Inhibition of PDE3AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Heriot-Watt University

Curated by ChEMBL
LigandPNGBDBM50224537(2-(3-(2-(2-(4-chlorophenyl)-4-methylthiazol-5-yl)e...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of PTP1B expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A(Homo sapiens (Human))
University Of Paisley

Curated by ChEMBL
LigandPNGBDBM50372898(CHEMBL255130)
Affinity DataIC50:  1.05E+4nMAssay Description:Inhibition of PDE3AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A(Homo sapiens (Human))
University Of Paisley

Curated by ChEMBL
LigandPNGBDBM50236078(5-(3-(cyclopentyloxy)-4-methoxybenzylidene)-2-thio...)
Affinity DataIC50:  1.08E+4nMAssay Description:Inhibition of PDE3AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
University Of Paisley

Curated by ChEMBL
LigandPNGBDBM50372910(CHEMBL255611)
Affinity DataIC50:  1.12E+4nMAssay Description:Inhibition of PDE4BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Heriot-Watt University

Curated by ChEMBL
LigandPNGBDBM50224549(2-(4-(4-methoxybenzyloxy)-3-(2-(2-(4-chlorophenyl)...)
Affinity DataIC50:  1.20E+4nMAssay Description:Inhibition of PTP1B expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Heriot-Watt University

Curated by ChEMBL
LigandPNGBDBM50224546(2-(3-(2-(2-(4-chlorophenyl)-4-methylthiazol-5-yl)e...)
Affinity DataIC50:  1.20E+4nMAssay Description:Inhibition of PTP1B expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
University Of Paisley

Curated by ChEMBL
LigandPNGBDBM50372909(CHEMBL255421)
Affinity DataIC50:  1.41E+4nMAssay Description:Inhibition of PDE4BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
University Of Paisley

Curated by ChEMBL
LigandPNGBDBM50372898(CHEMBL255130)
Affinity DataIC50:  1.79E+4nMAssay Description:Inhibition of PDE4BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
University Of Paisley

Curated by ChEMBL
LigandPNGBDBM50372898(CHEMBL255130)
Affinity DataIC50:  1.79E+4nMAssay Description:Inhibition of PDE4BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Heriot-Watt University

Curated by ChEMBL
LigandPNGBDBM50224543(2-(4-(4-fluorobenzyloxy)-3-(2-(2-(4-chlorophenyl)-...)
Affinity DataIC50:  2.30E+4nMAssay Description:Inhibition of PTP1B expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A(Homo sapiens (Human))
University Of Paisley

Curated by ChEMBL
LigandPNGBDBM50372904(CHEMBL404723)
Affinity DataIC50:  2.50E+4nMAssay Description:Inhibition of PDE3AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Heriot-Watt University

Curated by ChEMBL
LigandPNGBDBM50224536(2-(1-benzyl-5-(2-(2-(4-chlorophenyl)-4-methylthiaz...)
Affinity DataIC50:  2.70E+4nMAssay Description:Inhibition of PTP1B expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A(Homo sapiens (Human))
University Of Paisley

Curated by ChEMBL
LigandPNGBDBM50372901(CHEMBL255820)
Affinity DataIC50:  2.85E+4nMAssay Description:Inhibition of PDE3AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
University Of Paisley

Curated by ChEMBL
LigandPNGBDBM50372901(CHEMBL255820)
Affinity DataIC50:  3.04E+4nMAssay Description:Inhibition of PDE4BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Heriot-Watt University

Curated by ChEMBL
LigandPNGBDBM50224548(2-(5-(2-(2-(4-chlorophenyl)-4-methylthiazol-5-yl)e...)
Affinity DataIC50:  3.20E+4nMAssay Description:Inhibition of PTP1B expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Heriot-Watt University

Curated by ChEMBL
LigandPNGBDBM50224542(2-(3-(2-(2-(4-chlorophenyl)-4-methylthiazol-5-yl)e...)
Affinity DataIC50:  3.60E+4nMAssay Description:Inhibition of PTP1B expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Heriot-Watt University

Curated by ChEMBL
LigandPNGBDBM50224545(2-(3-(2-(2-(4-chlorophenyl)-4-methylthiazol-5-yl)e...)
Affinity DataIC50:  3.70E+4nMAssay Description:Inhibition of PTP1B expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A(Homo sapiens (Human))
University Of Paisley

Curated by ChEMBL
LigandPNGBDBM50372905(CHEMBL270636)
Affinity DataIC50:  3.98E+4nMAssay Description:Inhibition of PDE3AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
University Of Paisley

Curated by ChEMBL
LigandPNGBDBM50372903(CHEMBL255821)
Affinity DataIC50:  5.47E+4nMAssay Description:Inhibition of PDE4BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Heriot-Watt University

Curated by ChEMBL
LigandPNGBDBM50224550(2-(5-(2-(2-(4-chlorophenyl)-4-methylthiazol-5-yl)e...)
Affinity DataIC50:  5.90E+4nMAssay Description:Inhibition of PTP1B expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
University Of Paisley

Curated by ChEMBL
LigandPNGBDBM50372915(CHEMBL256425)
Affinity DataIC50:  6.48E+4nMAssay Description:Inhibition of PDE4BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A(Homo sapiens (Human))
University Of Paisley

Curated by ChEMBL
LigandPNGBDBM50372902(CHEMBL270637)
Affinity DataIC50:  8.00E+4nMAssay Description:Inhibition of PDE3AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Heriot-Watt University

Curated by ChEMBL
LigandPNGBDBM50224547(2-(3-(2-(2-(4-chlorophenyl)-4-methylthiazol-5-yl)e...)
Affinity DataIC50:  1.05E+5nMAssay Description:Inhibition of PTP1B expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Heriot-Watt University

Curated by ChEMBL
LigandPNGBDBM13990(5-{2-fluoro-5-[(1E)-3-[3-hydroxy-2-(methoxycarbony...)
Affinity DataIC50:  1.10E+5nMAssay Description:Inhibition of PTP1B expressed in Sf9 cellsMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Heriot-Watt University

Curated by ChEMBL
LigandPNGBDBM50224540(3,3,3-trifluoro-2-hydroxy-2-(5-(2-(3-hydroxy-2-(me...)
Affinity DataIC50:  1.23E+5nMAssay Description:Inhibition of PTP1B expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Heriot-Watt University

Curated by ChEMBL
LigandPNGBDBM50224538(2-(7-(benzyloxy)-1-(methoxymethyl)-1H-indol-3-yl)-...)
Affinity DataIC50:  1.76E+5nMAssay Description:Inhibition of PTP1B expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Heriot-Watt University

Curated by ChEMBL
LigandPNGBDBM50224539(2-(6-(benzyloxy)-1-(methoxymethyl)-1H-indol-3-yl)-...)
Affinity DataIC50:  3.82E+5nMAssay Description:Inhibition of PTP1B expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Heriot-Watt University

Curated by ChEMBL
LigandPNGBDBM50224544(2-(4-(carboxymethoxy)-3-(2-(2-(4-chlorophenyl)-4-m...)
Affinity DataIC50:  5.00E+5nMAssay Description:Inhibition of PTP1B expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed