TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
Osaka University
Curated by ChEMBL
Osaka University
Curated by ChEMBL
Affinity DataKi: 5nMAssay Description:Inhibition of FTase (unknown origin)-mediated K-Ras4B model peptide KKKKKKSK(Dans)TKCVIM farnesylation by microplate reader analysisMore data for this Ligand-Target Pair
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
Osaka University
Curated by ChEMBL
Osaka University
Curated by ChEMBL
Affinity DataKi: 15nMAssay Description:Inhibition of recombinant FTase (unknown origin)-mediated K-Ras4B model peptide KKKKKKSK(Dans)TKCVIM farnesylation by fluorescence plate reader analy...More data for this Ligand-Target Pair
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
Osaka University
Curated by ChEMBL
Osaka University
Curated by ChEMBL
Affinity DataKi: 785nMAssay Description:Inhibition of recombinant FTase (unknown origin)-mediated K-Ras4B model peptide KKKKKKSK(Dans)TKCVIM farnesylation by fluorescence plate reader analy...More data for this Ligand-Target Pair
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
Osaka University
Curated by ChEMBL
Osaka University
Curated by ChEMBL
Affinity DataKi: 837nMAssay Description:Inhibition of recombinant FTase (unknown origin)-mediated K-Ras4B model peptide KKKKKKSK(Dans)TKCVIM farnesylation by fluorescence plate reader analy...More data for this Ligand-Target Pair
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
Osaka University
Curated by ChEMBL
Osaka University
Curated by ChEMBL
Affinity DataKi: 1.10E+3nMAssay Description:Inhibition of FTase (unknown origin)-mediated K-Ras4B model peptide KKKKKKSK(Dans)TKCVIM farnesylation by microplate reader analysisMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Senju Pharmaceutical
US Patent
Senju Pharmaceutical
US Patent
Affinity DataIC50: 0.910nMAssay Description:Measurement of the kinase inhibitory activity of each compound produced in Examples was conducted using the Off-chip Mobility Shift Assay. For this t...More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Senju Pharmaceutical
US Patent
Senju Pharmaceutical
US Patent
Affinity DataIC50: 2.80nMAssay Description:Measurement of the kinase inhibitory activity of each compound produced in Examples was conducted using the Off-chip Mobility Shift Assay. For this t...More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Senju Pharmaceutical
US Patent
Senju Pharmaceutical
US Patent
Affinity DataIC50: 2.90nMAssay Description:Measurement of the kinase inhibitory activity of each compound produced in Examples was conducted using the Off-chip Mobility Shift Assay. For this t...More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Senju Pharmaceutical
US Patent
Senju Pharmaceutical
US Patent
Affinity DataIC50: 3.10nMAssay Description:Measurement of the kinase inhibitory activity of each compound produced in Examples was conducted using the Off-chip Mobility Shift Assay. For this t...More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Senju Pharmaceutical
US Patent
Senju Pharmaceutical
US Patent
Affinity DataIC50: 3.40nMAssay Description:Measurement of the kinase inhibitory activity of each compound produced in Examples was conducted using the Off-chip Mobility Shift Assay. For this t...More data for this Ligand-Target Pair
Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar
Ligand InfoPC sid
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Senju Pharmaceutical
US Patent
Senju Pharmaceutical
US Patent
Affinity DataIC50: 3.5nMAssay Description:Measurement of the kinase inhibitory activity of each compound produced in Examples was conducted using the Off-chip Mobility Shift Assay. For this t...More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Senju Pharmaceutical
US Patent
Senju Pharmaceutical
US Patent
Affinity DataIC50: 3.70nMAssay Description:Measurement of the kinase inhibitory activity of each compound produced in Examples was conducted using the Off-chip Mobility Shift Assay. For this t...More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Senju Pharmaceutical
US Patent
Senju Pharmaceutical
US Patent
Affinity DataIC50: 3.70nMAssay Description:Measurement of the kinase inhibitory activity of each compound produced in Examples was conducted using the Off-chip Mobility Shift Assay. For this t...More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Senju Pharmaceutical
US Patent
Senju Pharmaceutical
US Patent
Affinity DataIC50: 3.90nMAssay Description:Measurement of the kinase inhibitory activity of each compound produced in Examples was conducted using the Off-chip Mobility Shift Assay. For this t...More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Senju Pharmaceutical
US Patent
Senju Pharmaceutical
US Patent
Affinity DataIC50: 3.90nMAssay Description:Measurement of the kinase inhibitory activity of each compound produced in Examples was conducted using the Off-chip Mobility Shift Assay. For this t...More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Senju Pharmaceutical
US Patent
Senju Pharmaceutical
US Patent
Affinity DataIC50: 4nMAssay Description:Measurement of the kinase inhibitory activity of each compound produced in Examples was conducted using the Off-chip Mobility Shift Assay. For this t...More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Senju Pharmaceutical
US Patent
Senju Pharmaceutical
US Patent
Affinity DataIC50: 4nMAssay Description:Measurement of the kinase inhibitory activity of each compound produced in Examples was conducted using the Off-chip Mobility Shift Assay. For this t...More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Senju Pharmaceutical
US Patent
Senju Pharmaceutical
US Patent
Affinity DataIC50: 4.20nMAssay Description:Measurement of the kinase inhibitory activity of each compound produced in Examples was conducted using the Off-chip Mobility Shift Assay. For this t...More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Senju Pharmaceutical
US Patent
Senju Pharmaceutical
US Patent
Affinity DataIC50: 4.20nMAssay Description:Measurement of the kinase inhibitory activity of each compound produced in Examples was conducted using the Off-chip Mobility Shift Assay. For this t...More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Senju Pharmaceutical
US Patent
Senju Pharmaceutical
US Patent
Affinity DataIC50: 4.20nMAssay Description:Measurement of the kinase inhibitory activity of each compound produced in Examples was conducted using the Off-chip Mobility Shift Assay. For this t...More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Senju Pharmaceutical
US Patent
Senju Pharmaceutical
US Patent
Affinity DataIC50: 4.30nMAssay Description:Measurement of the kinase inhibitory activity of each compound produced in Examples was conducted using the Off-chip Mobility Shift Assay. For this t...More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Senju Pharmaceutical
US Patent
Senju Pharmaceutical
US Patent
Affinity DataIC50: 4.5nMAssay Description:Measurement of the kinase inhibitory activity of each compound produced in Examples was conducted using the Off-chip Mobility Shift Assay. For this t...More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Senju Pharmaceutical
US Patent
Senju Pharmaceutical
US Patent
Affinity DataIC50: 4.60nMAssay Description:Measurement of the kinase inhibitory activity of each compound produced in Examples was conducted using the Off-chip Mobility Shift Assay. For this t...More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Senju Pharmaceutical
US Patent
Senju Pharmaceutical
US Patent
Affinity DataIC50: 4.70nMAssay Description:Measurement of the kinase inhibitory activity of each compound produced in Examples was conducted using the Off-chip Mobility Shift Assay. For this t...More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Senju Pharmaceutical
US Patent
Senju Pharmaceutical
US Patent
Affinity DataIC50: 4.80nMAssay Description:Measurement of the kinase inhibitory activity of each compound produced in Examples was conducted using the Off-chip Mobility Shift Assay. For this t...More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Senju Pharmaceutical
US Patent
Senju Pharmaceutical
US Patent
Affinity DataIC50: 4.90nMAssay Description:Measurement of the kinase inhibitory activity of each compound produced in Examples was conducted using the Off-chip Mobility Shift Assay. For this t...More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Senju Pharmaceutical
US Patent
Senju Pharmaceutical
US Patent
Affinity DataIC50: 5.10nMAssay Description:Measurement of the kinase inhibitory activity of each compound produced in Examples was conducted using the Off-chip Mobility Shift Assay. For this t...More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Senju Pharmaceutical
US Patent
Senju Pharmaceutical
US Patent
Affinity DataIC50: 5.20nMAssay Description:Measurement of the kinase inhibitory activity of each compound produced in Examples was conducted using the Off-chip Mobility Shift Assay. For this t...More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Senju Pharmaceutical
US Patent
Senju Pharmaceutical
US Patent
Affinity DataIC50: 5.5nMAssay Description:Measurement of the kinase inhibitory activity of each compound produced in Examples was conducted using the Off-chip Mobility Shift Assay. For this t...More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Senju Pharmaceutical
US Patent
Senju Pharmaceutical
US Patent
Affinity DataIC50: 5.5nMAssay Description:Measurement of the kinase inhibitory activity of each compound produced in Examples was conducted using the Off-chip Mobility Shift Assay. For this t...More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Senju Pharmaceutical
US Patent
Senju Pharmaceutical
US Patent
Affinity DataIC50: 5.70nMAssay Description:Measurement of the kinase inhibitory activity of each compound produced in Examples was conducted using the Off-chip Mobility Shift Assay. For this t...More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Senju Pharmaceutical
US Patent
Senju Pharmaceutical
US Patent
Affinity DataIC50: 5.80nMAssay Description:Measurement of the kinase inhibitory activity of each compound produced in Examples was conducted using the Off-chip Mobility Shift Assay. For this t...More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Senju Pharmaceutical
US Patent
Senju Pharmaceutical
US Patent
Affinity DataIC50: 5.90nMAssay Description:Measurement of the kinase inhibitory activity of each compound produced in Examples was conducted using the Off-chip Mobility Shift Assay. For this t...More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Senju Pharmaceutical
US Patent
Senju Pharmaceutical
US Patent
Affinity DataIC50: 5.90nMAssay Description:Measurement of the kinase inhibitory activity of each compound produced in Examples was conducted using the Off-chip Mobility Shift Assay. For this t...More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Senju Pharmaceutical
US Patent
Senju Pharmaceutical
US Patent
Affinity DataIC50: 6.10nMAssay Description:Measurement of the kinase inhibitory activity of each compound produced in Examples was conducted using the Off-chip Mobility Shift Assay. For this t...More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Senju Pharmaceutical
US Patent
Senju Pharmaceutical
US Patent
Affinity DataIC50: 6.40nMAssay Description:Measurement of the kinase inhibitory activity of each compound produced in Examples was conducted using the Off-chip Mobility Shift Assay. For this t...More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Senju Pharmaceutical
US Patent
Senju Pharmaceutical
US Patent
Affinity DataIC50: 6.70nMAssay Description:Measurement of the kinase inhibitory activity of each compound produced in Examples was conducted using the Off-chip Mobility Shift Assay. For this t...More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Senju Pharmaceutical
US Patent
Senju Pharmaceutical
US Patent
Affinity DataIC50: 7.20nMAssay Description:Measurement of the kinase inhibitory activity of each compound produced in Examples was conducted using the Off-chip Mobility Shift Assay. For this t...More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Senju Pharmaceutical
US Patent
Senju Pharmaceutical
US Patent
Affinity DataIC50: 7.60nMAssay Description:Measurement of the kinase inhibitory activity of each compound produced in Examples was conducted using the Off-chip Mobility Shift Assay. For this t...More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Senju Pharmaceutical
US Patent
Senju Pharmaceutical
US Patent
Affinity DataIC50: 7.70nMAssay Description:Measurement of the kinase inhibitory activity of each compound produced in Examples was conducted using the Off-chip Mobility Shift Assay. For this t...More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Senju Pharmaceutical
US Patent
Senju Pharmaceutical
US Patent
Affinity DataIC50: 7.90nMAssay Description:Measurement of the kinase inhibitory activity of each compound produced in Examples was conducted using the Off-chip Mobility Shift Assay. For this t...More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Senju Pharmaceutical
US Patent
Senju Pharmaceutical
US Patent
Affinity DataIC50: 8nMAssay Description:Measurement of the kinase inhibitory activity of each compound produced in Examples was conducted using the Off-chip Mobility Shift Assay. For this t...More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Senju Pharmaceutical
US Patent
Senju Pharmaceutical
US Patent
Affinity DataIC50: 8.80nMAssay Description:Measurement of the kinase inhibitory activity of each compound produced in Examples was conducted using the Off-chip Mobility Shift Assay. For this t...More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Senju Pharmaceutical
US Patent
Senju Pharmaceutical
US Patent
Affinity DataIC50: 8.90nMAssay Description:Measurement of the kinase inhibitory activity of each compound produced in Examples was conducted using the Off-chip Mobility Shift Assay. For this t...More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Senju Pharmaceutical
US Patent
Senju Pharmaceutical
US Patent
Affinity DataIC50: 8.90nMAssay Description:Measurement of the kinase inhibitory activity of each compound produced in Examples was conducted using the Off-chip Mobility Shift Assay. For this t...More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Senju Pharmaceutical
US Patent
Senju Pharmaceutical
US Patent
Affinity DataIC50: 9.20nMAssay Description:Measurement of the kinase inhibitory activity of each compound produced in Examples was conducted using the Off-chip Mobility Shift Assay. For this t...More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Senju Pharmaceutical
US Patent
Senju Pharmaceutical
US Patent
Affinity DataIC50: 9.70nMAssay Description:Measurement of the kinase inhibitory activity of each compound produced in Examples was conducted using the Off-chip Mobility Shift Assay. For this t...More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Senju Pharmaceutical
US Patent
Senju Pharmaceutical
US Patent
Affinity DataIC50: 9.90nMAssay Description:Measurement of the kinase inhibitory activity of each compound produced in Examples was conducted using the Off-chip Mobility Shift Assay. For this t...More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Senju Pharmaceutical
US Patent
Senju Pharmaceutical
US Patent
Affinity DataIC50: 10nMAssay Description:Measurement of the kinase inhibitory activity of each compound produced in Examples was conducted using the Off-chip Mobility Shift Assay. For this t...More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Senju Pharmaceutical
US Patent
Senju Pharmaceutical
US Patent
Affinity DataIC50: 11nMAssay Description:Measurement of the kinase inhibitory activity of each compound produced in Examples was conducted using the Off-chip Mobility Shift Assay. For this t...More data for this Ligand-Target Pair