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Found 573 with Last Name = 'maekawa' and Initial = 't'
TargetAcyl-CoA (8-3)-desaturase(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50245999(CHEMBL4084502)
Affinity DataIC50:  0.520nMAssay Description:Inhibition of D5D in human HepG2 cells assessed as [14C]AA formation from [14C]DGLA preincubated for 30 mins followed by [14C]eicosatrienoic acid add...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetyl-coenzyme A transporter 1(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM107366(US8592431, 167)
Affinity DataIC50:  0.800nMpH: 7.4Assay Description:The binding assay was performed using 22.5 pM [125I]-angiotensin II [manufactured by PerkinElmer, USA] (9 μg) in the presence of AT1 membrane an...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetEnteropeptidase(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50595346(CHEMBL5189108)
Affinity DataIC50:  0.810nMAssay Description:Inhibition of human recombinant Enteropeptidase assessed as inhibition based on steady state using 5FAM-Abu-Gly-Asp -Asp-Asp -Lys-Ile-Val-Gly-Gly-Lys...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetEnteropeptidase(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50595349(CHEMBL5202756)
Affinity DataIC50:  0.820nMAssay Description:Inhibition of human recombinant Enteropeptidase assessed as inhibition based on steady state using 5FAM-Abu-Gly-Asp -Asp-Asp -Lys-Ile-Val-Gly-Gly-Lys...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAcetyl-coenzyme A transporter 1(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM107347(US8592431, 135)
Affinity DataIC50:  0.900nMpH: 7.4Assay Description:The binding assay was performed using 22.5 pM [125I]-angiotensin II [manufactured by PerkinElmer, USA] (9 μg) in the presence of AT1 membrane an...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAcyl-CoA (8-3)-desaturase(Rattus norvegicus)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50245999(CHEMBL4084502)
Affinity DataIC50: <1nMAssay Description:Displacement of [3H]T-3364366 from D5D in rat liver microsomal membrane preincubated for 15 mins followed by radioligand addition measured after 150 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetyl-coenzyme A transporter 1(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM107364(US8592431, 264)
Affinity DataIC50:  1nMpH: 7.4Assay Description:The binding assay was performed using 22.5 pM [125I]-angiotensin II [manufactured by PerkinElmer, USA] (9 μg) in the presence of AT1 membrane an...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAcetyl-coenzyme A transporter 1(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM107354(US8592431, 147)
Affinity DataIC50:  1nMpH: 7.4Assay Description:The binding assay was performed using 22.5 pM [125I]-angiotensin II [manufactured by PerkinElmer, USA] (9 μg) in the presence of AT1 membrane an...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAcetyl-coenzyme A transporter 1(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM107435(US8592431, 354)
Affinity DataIC50:  1.20nMpH: 7.4Assay Description:The binding assay was performed using 22.5 pM [125I]-angiotensin II [manufactured by PerkinElmer, USA] (9 μg) in the presence of AT1 membrane an...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAcetyl-coenzyme A transporter 1(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM107361(US8592431, 241 | US8592431, 242)
Affinity DataIC50:  1.20nMpH: 7.4Assay Description:The binding assay was performed using 22.5 pM [125I]-angiotensin II [manufactured by PerkinElmer, USA] (9 μg) in the presence of AT1 membrane an...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAcetyl-coenzyme A transporter 1(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM107445(US8592431, 376)
Affinity DataIC50:  1.20nMpH: 7.4Assay Description:The binding assay was performed using 22.5 pM [125I]-angiotensin II [manufactured by PerkinElmer, USA] (9 μg) in the presence of AT1 membrane an...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetEnteropeptidase(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50595352(CHEMBL5175180)
Affinity DataIC50:  1.20nMAssay Description:Inhibition of human recombinant Enteropeptidase assessed as inhibition based on steady state using 5FAM-Abu-Gly-Asp -Asp-Asp -Lys-Ile-Val-Gly-Gly-Lys...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAcetyl-coenzyme A transporter 1(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM107350(US8592431, 138)
Affinity DataIC50:  1.30nMpH: 7.4Assay Description:The binding assay was performed using 22.5 pM [125I]-angiotensin II [manufactured by PerkinElmer, USA] (9 μg) in the presence of AT1 membrane an...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAcetyl-coenzyme A transporter 1(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM107340(US8592431, 117)
Affinity DataIC50:  1.30nMpH: 7.4Assay Description:The binding assay was performed using 22.5 pM [125I]-angiotensin II [manufactured by PerkinElmer, USA] (9 μg) in the presence of AT1 membrane an...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAcetyl-coenzyme A transporter 1(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM107318(US8592431, 2)
Affinity DataIC50:  1.30nMpH: 7.4Assay Description:The binding assay was performed using 22.5 pM [125I]-angiotensin II [manufactured by PerkinElmer, USA] (9 μg) in the presence of AT1 membrane an...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAcetyl-coenzyme A transporter 1(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM107348(US8592431, 136)
Affinity DataIC50:  1.30nMpH: 7.4Assay Description:The binding assay was performed using 22.5 pM [125I]-angiotensin II [manufactured by PerkinElmer, USA] (9 μg) in the presence of AT1 membrane an...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAcetyl-coenzyme A transporter 1(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM107346(US8592431, 134)
Affinity DataIC50:  1.30nMpH: 7.4Assay Description:The binding assay was performed using 22.5 pM [125I]-angiotensin II [manufactured by PerkinElmer, USA] (9 μg) in the presence of AT1 membrane an...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAcetyl-coenzyme A transporter 1(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM107361(US8592431, 241 | US8592431, 242)
Affinity DataIC50:  1.30nMpH: 7.4Assay Description:The binding assay was performed using 22.5 pM [125I]-angiotensin II [manufactured by PerkinElmer, USA] (9 μg) in the presence of AT1 membrane an...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAcetyl-coenzyme A transporter 1(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM107365(US8592431, 166)
Affinity DataIC50:  1.30nMpH: 7.4Assay Description:The binding assay was performed using 22.5 pM [125I]-angiotensin II [manufactured by PerkinElmer, USA] (9 μg) in the presence of AT1 membrane an...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAcetyl-coenzyme A transporter 1(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM107368(US8592431, 169)
Affinity DataIC50:  1.40nMpH: 7.4Assay Description:The binding assay was performed using 22.5 pM [125I]-angiotensin II [manufactured by PerkinElmer, USA] (9 μg) in the presence of AT1 membrane an...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAcetyl-coenzyme A transporter 1(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM107330(US8592431, 69)
Affinity DataIC50:  1.40nMpH: 7.4Assay Description:The binding assay was performed using 22.5 pM [125I]-angiotensin II [manufactured by PerkinElmer, USA] (9 μg) in the presence of AT1 membrane an...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAcetyl-coenzyme A transporter 1(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM107434(US8592431, 352)
Affinity DataIC50:  1.40nMpH: 7.4Assay Description:The binding assay was performed using 22.5 pM [125I]-angiotensin II [manufactured by PerkinElmer, USA] (9 μg) in the presence of AT1 membrane an...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAcetyl-coenzyme A transporter 1(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM107431(US8592431, 339)
Affinity DataIC50:  1.40nMpH: 7.4Assay Description:The binding assay was performed using 22.5 pM [125I]-angiotensin II [manufactured by PerkinElmer, USA] (9 μg) in the presence of AT1 membrane an...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAcetyl-coenzyme A transporter 1(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM107367(US8592431, 168)
Affinity DataIC50:  1.40nMpH: 7.4Assay Description:The binding assay was performed using 22.5 pM [125I]-angiotensin II [manufactured by PerkinElmer, USA] (9 μg) in the presence of AT1 membrane an...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAcetyl-coenzyme A transporter 1(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM107349(US8592431, 137)
Affinity DataIC50:  1.40nMpH: 7.4Assay Description:The binding assay was performed using 22.5 pM [125I]-angiotensin II [manufactured by PerkinElmer, USA] (9 μg) in the presence of AT1 membrane an...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAcetyl-coenzyme A transporter 1(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM107353(US8592431, 144)
Affinity DataIC50:  1.40nMpH: 7.4Assay Description:The binding assay was performed using 22.5 pM [125I]-angiotensin II [manufactured by PerkinElmer, USA] (9 μg) in the presence of AT1 membrane an...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAcetyl-coenzyme A transporter 1(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM107356(US8592431, 150)
Affinity DataIC50:  1.40nMpH: 7.4Assay Description:The binding assay was performed using 22.5 pM [125I]-angiotensin II [manufactured by PerkinElmer, USA] (9 μg) in the presence of AT1 membrane an...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAcetyl-coenzyme A transporter 1(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM107338(US8592431, 113)
Affinity DataIC50:  1.5nMpH: 7.4Assay Description:The binding assay was performed using 22.5 pM [125I]-angiotensin II [manufactured by PerkinElmer, USA] (9 μg) in the presence of AT1 membrane an...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAcetyl-coenzyme A transporter 1(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM107331(US8592431, 73)
Affinity DataIC50:  1.5nMpH: 7.4Assay Description:The binding assay was performed using 22.5 pM [125I]-angiotensin II [manufactured by PerkinElmer, USA] (9 μg) in the presence of AT1 membrane an...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAcyl-CoA (8-3)-desaturase(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50245998(CHEMBL4064555)
Affinity DataIC50:  1.5nMAssay Description:Inhibition of D5D in human HepG2 cells assessed as [14C]AA formation from [14C]DGLA preincubated for 30 mins followed by [14C]eicosatrienoic acid add...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetyl-coenzyme A transporter 1(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM107334(US8592431, 83)
Affinity DataIC50:  1.5nMpH: 7.4Assay Description:The binding assay was performed using 22.5 pM [125I]-angiotensin II [manufactured by PerkinElmer, USA] (9 μg) in the presence of AT1 membrane an...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAcyl-CoA (8-3)-desaturase(Rattus norvegicus)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50245998(CHEMBL4064555)
Affinity DataIC50:  1.5nMAssay Description:Displacement of [3H]T-3364366 from D5D in rat liver microsomal membrane preincubated for 15 mins followed by radioligand addition measured after 150 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetyl-coenzyme A transporter 1(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM107336(US8592431, 108)
Affinity DataIC50:  1.5nMpH: 7.4Assay Description:The binding assay was performed using 22.5 pM [125I]-angiotensin II [manufactured by PerkinElmer, USA] (9 μg) in the presence of AT1 membrane an...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAcetyl-coenzyme A transporter 1(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM107393(US8592431, 228)
Affinity DataIC50:  1.5nMpH: 7.4Assay Description:The binding assay was performed using 22.5 pM [125I]-angiotensin II [manufactured by PerkinElmer, USA] (9 μg) in the presence of AT1 membrane an...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAcetyl-coenzyme A transporter 1(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM47107(US8592431, 155)
Affinity DataIC50:  1.60nMAssay Description:The binding assay was performed using 22.5 pM [125I]-angiotensin II [manufactured by PerkinElmer, USA] (9 μg) in the presence of AT1 membrane an...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAcetyl-coenzyme A transporter 1(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM107430(US8592431, 338)
Affinity DataIC50:  1.60nMpH: 7.4Assay Description:The binding assay was performed using 22.5 pM [125I]-angiotensin II [manufactured by PerkinElmer, USA] (9 μg) in the presence of AT1 membrane an...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAcetyl-coenzyme A transporter 1(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM107390(US8592431, 216)
Affinity DataIC50:  1.60nMpH: 7.4Assay Description:The binding assay was performed using 22.5 pM [125I]-angiotensin II [manufactured by PerkinElmer, USA] (9 μg) in the presence of AT1 membrane an...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAcetyl-coenzyme A transporter 1(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM107463(US8592431, 520 | US8592431, 521)
Affinity DataIC50:  1.60nMpH: 7.4Assay Description:The binding assay was performed using 22.5 pM [125I]-angiotensin II [manufactured by PerkinElmer, USA] (9 μg) in the presence of AT1 membrane an...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAcetyl-coenzyme A transporter 1(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM107462(US8592431, 437)
Affinity DataIC50:  1.60nMpH: 7.4Assay Description:The binding assay was performed using 22.5 pM [125I]-angiotensin II [manufactured by PerkinElmer, USA] (9 μg) in the presence of AT1 membrane an...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAcetyl-coenzyme A transporter 1(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM107454(US8592431, 413)
Affinity DataIC50:  1.60nMpH: 7.4Assay Description:The binding assay was performed using 22.5 pM [125I]-angiotensin II [manufactured by PerkinElmer, USA] (9 μg) in the presence of AT1 membrane an...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAcetyl-coenzyme A transporter 1(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM107381(US8592431, 191)
Affinity DataIC50:  1.60nMpH: 7.4Assay Description:The binding assay was performed using 22.5 pM [125I]-angiotensin II [manufactured by PerkinElmer, USA] (9 μg) in the presence of AT1 membrane an...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetEnteropeptidase(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50595350(CHEMBL5182597)
Affinity DataIC50:  1.60nMAssay Description:Inhibition of human recombinant Enteropeptidase assessed as inhibition based on steady state using 5FAM-Abu-Gly-Asp -Asp-Asp -Lys-Ile-Val-Gly-Gly-Lys...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAcetyl-coenzyme A transporter 1(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM107369(US8592431, 170)
Affinity DataIC50:  1.60nMpH: 7.4Assay Description:The binding assay was performed using 22.5 pM [125I]-angiotensin II [manufactured by PerkinElmer, USA] (9 μg) in the presence of AT1 membrane an...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAcetyl-coenzyme A transporter 1(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM107363(US8592431, 163)
Affinity DataIC50:  1.60nMpH: 7.4Assay Description:The binding assay was performed using 22.5 pM [125I]-angiotensin II [manufactured by PerkinElmer, USA] (9 μg) in the presence of AT1 membrane an...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAcetyl-coenzyme A transporter 1(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM107357(US8592431, 151)
Affinity DataIC50:  1.60nMpH: 7.4Assay Description:The binding assay was performed using 22.5 pM [125I]-angiotensin II [manufactured by PerkinElmer, USA] (9 μg) in the presence of AT1 membrane an...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAcetyl-coenzyme A transporter 1(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM107437(US8592431, 360)
Affinity DataIC50:  1.70nMpH: 7.4Assay Description:The binding assay was performed using 22.5 pM [125I]-angiotensin II [manufactured by PerkinElmer, USA] (9 μg) in the presence of AT1 membrane an...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAcetyl-coenzyme A transporter 1(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM107436(US8592431, 355)
Affinity DataIC50:  1.70nMpH: 7.4Assay Description:The binding assay was performed using 22.5 pM [125I]-angiotensin II [manufactured by PerkinElmer, USA] (9 μg) in the presence of AT1 membrane an...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAcetyl-coenzyme A transporter 1(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM107329(US8592431, 68)
Affinity DataIC50:  1.70nMpH: 7.4Assay Description:The binding assay was performed using 22.5 pM [125I]-angiotensin II [manufactured by PerkinElmer, USA] (9 μg) in the presence of AT1 membrane an...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAcetyl-coenzyme A transporter 1(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM107320(US8592431, 5)
Affinity DataIC50:  1.70nMpH: 7.4Assay Description:The binding assay was performed using 22.5 pM [125I]-angiotensin II [manufactured by PerkinElmer, USA] (9 μg) in the presence of AT1 membrane an...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAcetyl-coenzyme A transporter 1(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM107460(US8592431, 435)
Affinity DataIC50:  1.70nMpH: 7.4Assay Description:The binding assay was performed using 22.5 pM [125I]-angiotensin II [manufactured by PerkinElmer, USA] (9 μg) in the presence of AT1 membrane an...More data for this Ligand-Target Pair
In DepthDetails US Patent
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