Compile Data Set for Download or QSAR
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Found 180 with Last Name = 'martyn' and Initial = 'dc'
TargetCytochrome P450 2C19(Homo sapiens (Human))
Institute Infectious Diseases Initiative

Curated by ChEMBL
LigandPNGBDBM50301852(2-(3-methyl-1,2-dioxaspiro[4.5]decan-3-yl)-N-(pyri...)
Affinity DataIC50:  100nMAssay Description:Inhibition of human CYP2C19More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypanothione reductase(Trypanosoma brucei brucei)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50201774(3-(dimethylamino)-1-(3-nitrophenyl)propan-1-one hy...)
Affinity DataIC50:  340nMAssay Description:Inhibition of TR by DTNB-coupled assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Institute Infectious Diseases Initiative

Curated by ChEMBL
LigandPNGBDBM50301837(CHEMBL567374 | tert-butyl 3-(2-(2-(3-methyl-1,2-di...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of human CYP3A4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Institute Infectious Diseases Initiative

Curated by ChEMBL
LigandPNGBDBM50245848(CHEMBL462360 | N-(2-(7-chloroquinolin-4-ylamino)et...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of human CYP3A4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Institute Infectious Diseases Initiative

Curated by ChEMBL
LigandPNGBDBM50301847(CHEMBL565360 | N-(2-(2-(hydroxymethyl)phenylthio)b...)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of human CYP3A4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypanothione reductase(Trypanosoma brucei brucei)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50201776(3-(2,3-dimethylphenylamino)-1-(3-nitrophenyl)propa...)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of TR by DTNB-coupled assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Institute Infectious Diseases Initiative

Curated by ChEMBL
LigandPNGBDBM50301830(2-(3-methyl-1,2-dioxaspiro[4.5]decan-3-yl)-N-(3-(t...)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of human CYP2C19More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Institute Infectious Diseases Initiative

Curated by ChEMBL
LigandPNGBDBM50301845(2-(3-methyl-1,2-dioxaspiro[4.5]decan-3-yl)-N-(2-(p...)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition of human CYP3A4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Institute Infectious Diseases Initiative

Curated by ChEMBL
LigandPNGBDBM50301828(CHEMBL579199 | N-(3,5-dimethoxybenzyl)-2-(3-methyl...)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition of human CYP3A4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypanothione reductase(Trypanosoma brucei brucei)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM34731(1-(3-nitrophenyl)-3-phenylazanyl-propan-1-one | 3-...)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition of TR by DTNB-coupled assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Institute Infectious Diseases Initiative

Curated by ChEMBL
LigandPNGBDBM50301835(CHEMBL572184 | N-(3-bromobenzyl)-2-(3-methyl-1,2-d...)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibition of human CYP2C19More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Institute Infectious Diseases Initiative

Curated by ChEMBL
LigandPNGBDBM50301840(CHEMBL567376 | N-(2-aminobenzyl)-2-(3-methyl-1,2-d...)
Affinity DataIC50:  1.90E+3nMAssay Description:Inhibition of human CYP3A4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Institute Infectious Diseases Initiative

Curated by ChEMBL
LigandPNGBDBM50301828(CHEMBL579199 | N-(3,5-dimethoxybenzyl)-2-(3-methyl...)
Affinity DataIC50:  1.90E+3nMAssay Description:Inhibition of human CYP2C19More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Institute Infectious Diseases Initiative

Curated by ChEMBL
LigandPNGBDBM50301829(2-(3-methyl-1,2-dioxaspiro[4.5]decan-3-yl)-N-(3,4,...)
Affinity DataIC50:  1.90E+3nMAssay Description:Inhibition of human CYP3A4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypanothione reductase(Trypanosoma brucei brucei)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50201777(2,6-di-tert-butyl-4-((2-hydroxyethylamino)methyl)p...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of TR by DTNB-coupled assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Institute Infectious Diseases Initiative

Curated by ChEMBL
LigandPNGBDBM50301834(CHEMBL577694 | N-(3-chlorobenzyl)-2-(3-methyl-1,2-...)
Affinity DataIC50:  2.10E+3nMAssay Description:Inhibition of human CYP2C19More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Institute Infectious Diseases Initiative

Curated by ChEMBL
LigandPNGBDBM50301847(CHEMBL565360 | N-(2-(2-(hydroxymethyl)phenylthio)b...)
Affinity DataIC50:  2.20E+3nMAssay Description:Inhibition of human CYP2C9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Institute Infectious Diseases Initiative

Curated by ChEMBL
LigandPNGBDBM50301845(2-(3-methyl-1,2-dioxaspiro[4.5]decan-3-yl)-N-(2-(p...)
Affinity DataIC50:  2.20E+3nMAssay Description:Inhibition of human CYP2C19More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Institute Infectious Diseases Initiative

Curated by ChEMBL
LigandPNGBDBM50301827(CHEMBL578968 | N-(2-ethoxybenzyl)-2-(3-methyl-1,2-...)
Affinity DataIC50:  2.30E+3nMAssay Description:Inhibition of human CYP2C19More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Institute Infectious Diseases Initiative

Curated by ChEMBL
LigandPNGBDBM50301841(CHEMBL578588 | N-(4-(dimethylamino)benzyl)-2-(3-me...)
Affinity DataIC50:  2.30E+3nMAssay Description:Inhibition of human CYP2C19More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypanothione reductase(Trypanosoma brucei brucei)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50201781(CHEMBL233339 | butyl 4-(3-(3-nitrophenyl)-3-oxopro...)
Affinity DataIC50:  2.40E+3nMAssay Description:Inhibition of TR by DTNB-coupled assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Institute Infectious Diseases Initiative

Curated by ChEMBL
LigandPNGBDBM50301848(CHEMBL584886 | N-((2,3-dihydrobenzofuran-6-yl)meth...)
Affinity DataIC50:  2.60E+3nMAssay Description:Inhibition of human CYP3A4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Institute Infectious Diseases Initiative

Curated by ChEMBL
LigandPNGBDBM50301826(CHEMBL565361 | N-(3-methoxybenzyl)-2-(3-methyl-1,2...)
Affinity DataIC50:  2.60E+3nMAssay Description:Inhibition of human CYP2C19More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Institute Infectious Diseases Initiative

Curated by ChEMBL
LigandPNGBDBM50301836(CHEMBL565362 | N-(4-bromo-2-fluorobenzyl)-2-(3-met...)
Affinity DataIC50:  2.80E+3nMAssay Description:Inhibition of human CYP2C19More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypanothione reductase(Trypanosoma brucei brucei)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50201778(3-(dimethylamino)-1-(4-(methylsulfonyl)phenyl)prop...)
Affinity DataIC50:  2.90E+3nMAssay Description:Inhibition of TR by DTNB-coupled assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Institute Infectious Diseases Initiative

Curated by ChEMBL
LigandPNGBDBM50301833(2-(3-methyl-1,2-dioxaspiro[4.5]decan-3-yl)-N-(4-(t...)
Affinity DataIC50:  2.90E+3nMAssay Description:Inhibition of human CYP3A4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Institute Infectious Diseases Initiative

Curated by ChEMBL
LigandPNGBDBM50301848(CHEMBL584886 | N-((2,3-dihydrobenzofuran-6-yl)meth...)
Affinity DataIC50:  2.90E+3nMAssay Description:Inhibition of human CYP2C19More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Institute Infectious Diseases Initiative

Curated by ChEMBL
LigandPNGBDBM50301847(CHEMBL565360 | N-(2-(2-(hydroxymethyl)phenylthio)b...)
Affinity DataIC50:  2.90E+3nMAssay Description:Inhibition of human CYP2C19More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Institute Infectious Diseases Initiative

Curated by ChEMBL
LigandPNGBDBM50304834(CHEMBL578928 | GNF-Pf-2094 | N2-benzyl-N4-cyclohex...)
Affinity DataIC50:  3.10E+3nMAssay Description:Inhibition of human CYP1A2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Institute Infectious Diseases Initiative

Curated by ChEMBL
LigandPNGBDBM50301842(2-(3-methyl-1,2-dioxaspiro[4.5]decan-3-yl)-N-(4-ni...)
Affinity DataIC50:  3.20E+3nMAssay Description:Inhibition of human CYP2C19More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Institute Infectious Diseases Initiative

Curated by ChEMBL
LigandPNGBDBM50301830(2-(3-methyl-1,2-dioxaspiro[4.5]decan-3-yl)-N-(3-(t...)
Affinity DataIC50:  3.20E+3nMAssay Description:Inhibition of human CYP3A4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypanothione reductase(Trypanosoma brucei brucei)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50201782(1-(3,4-dichlorophenyl)-3-(dimethylamino)propan-1-o...)
Affinity DataIC50:  3.30E+3nMAssay Description:Inhibition of TR by DTNB-coupled assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Institute Infectious Diseases Initiative

Curated by ChEMBL
LigandPNGBDBM50301830(2-(3-methyl-1,2-dioxaspiro[4.5]decan-3-yl)-N-(3-(t...)
Affinity DataIC50:  3.30E+3nMAssay Description:Inhibition of human CYP2C9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypanothione reductase(Trypanosoma brucei brucei)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50201775(3-(3-fluorophenylamino)-1-(3-nitrophenyl)propan-1-...)
Affinity DataIC50:  3.30E+3nMAssay Description:Inhibition of TR by DTNB-coupled assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Institute Infectious Diseases Initiative

Curated by ChEMBL
LigandPNGBDBM50301834(CHEMBL577694 | N-(3-chlorobenzyl)-2-(3-methyl-1,2-...)
Affinity DataIC50:  3.40E+3nMAssay Description:Inhibition of human CYP2C9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Institute Infectious Diseases Initiative

Curated by ChEMBL
LigandPNGBDBM50245848(CHEMBL462360 | N-(2-(7-chloroquinolin-4-ylamino)et...)
Affinity DataIC50:  3.40E+3nMAssay Description:Inhibition of human CYP2C19More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Institute Infectious Diseases Initiative

Curated by ChEMBL
LigandPNGBDBM50301826(CHEMBL565361 | N-(3-methoxybenzyl)-2-(3-methyl-1,2...)
Affinity DataIC50:  3.70E+3nMAssay Description:Inhibition of human CYP3A4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Institute Infectious Diseases Initiative

Curated by ChEMBL
LigandPNGBDBM50301832(2-(3-methyl-1,2-dioxaspiro[4.5]decan-3-yl)-N-(2-(t...)
Affinity DataIC50:  3.70E+3nMAssay Description:Inhibition of human CYP2C19More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Institute Infectious Diseases Initiative

Curated by ChEMBL
LigandPNGBDBM50301835(CHEMBL572184 | N-(3-bromobenzyl)-2-(3-methyl-1,2-d...)
Affinity DataIC50:  3.70E+3nMAssay Description:Inhibition of human CYP2C9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Institute Infectious Diseases Initiative

Curated by ChEMBL
LigandPNGBDBM50301840(CHEMBL567376 | N-(2-aminobenzyl)-2-(3-methyl-1,2-d...)
Affinity DataIC50:  3.80E+3nMAssay Description:Inhibition of human CYP2C19More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Institute Infectious Diseases Initiative

Curated by ChEMBL
LigandPNGBDBM50301841(CHEMBL578588 | N-(4-(dimethylamino)benzyl)-2-(3-me...)
Affinity DataIC50:  3.80E+3nMAssay Description:Inhibition of human CYP1A2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Institute Infectious Diseases Initiative

Curated by ChEMBL
LigandPNGBDBM50301836(CHEMBL565362 | N-(4-bromo-2-fluorobenzyl)-2-(3-met...)
Affinity DataIC50:  3.90E+3nMAssay Description:Inhibition of human CYP2C9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Institute Infectious Diseases Initiative

Curated by ChEMBL
LigandPNGBDBM50245848(CHEMBL462360 | N-(2-(7-chloroquinolin-4-ylamino)et...)
Affinity DataIC50:  3.90E+3nMAssay Description:Inhibition of human CYP2D6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Institute Infectious Diseases Initiative

Curated by ChEMBL
LigandPNGBDBM50301839(CHEMBL578547 | methyl 4-((2-(3-methyl-1,2-dioxaspi...)
Affinity DataIC50:  3.90E+3nMAssay Description:Inhibition of human CYP2C19More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Institute Infectious Diseases Initiative

Curated by ChEMBL
LigandPNGBDBM50301833(2-(3-methyl-1,2-dioxaspiro[4.5]decan-3-yl)-N-(4-(t...)
Affinity DataIC50:  3.90E+3nMAssay Description:Inhibition of human CYP2C19More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Institute Infectious Diseases Initiative

Curated by ChEMBL
LigandPNGBDBM50301843(2-(3-methyl-1,2-dioxaspiro[4.5]decan-3-yl)-N-(4-(m...)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of human CYP2C19More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Institute Infectious Diseases Initiative

Curated by ChEMBL
LigandPNGBDBM50301833(2-(3-methyl-1,2-dioxaspiro[4.5]decan-3-yl)-N-(4-(t...)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of human CYP2C9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Institute Infectious Diseases Initiative

Curated by ChEMBL
LigandPNGBDBM50301826(CHEMBL565361 | N-(3-methoxybenzyl)-2-(3-methyl-1,2...)
Affinity DataIC50:  4.20E+3nMAssay Description:Inhibition of human CYP2C9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Institute Infectious Diseases Initiative

Curated by ChEMBL
LigandPNGBDBM50304834(CHEMBL578928 | GNF-Pf-2094 | N2-benzyl-N4-cyclohex...)
Affinity DataIC50:  4.20E+3nMAssay Description:Inhibition of human CYP2D6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Institute Infectious Diseases Initiative

Curated by ChEMBL
LigandPNGBDBM50301832(2-(3-methyl-1,2-dioxaspiro[4.5]decan-3-yl)-N-(2-(t...)
Affinity DataIC50:  4.20E+3nMAssay Description:Inhibition of human CYP3A4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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