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Found 28 with Last Name = 'mazzoni' and Initial = 'o'
TargetCannabinoid receptor 1(Rattus norvegicus (rat))
UniversitÀ

LigandPNGBDBM82141(WIN 55212-2)
Affinity DataKi:  7.30nM ΔG°:  -46.4kJ/molepH: 7.4 T: 2°CAssay Description:CB1 competitive assay were performed in rat cerebellar membranes using [3H]WIN 55212-2 from Perkin-Elmer as a radioligand.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Rattus norvegicus (rat))
UniversitÀ

LigandPNGBDBM82135(5-Substituted derivative, 5)
Affinity DataKi:  8.40nM ΔG°:  -46.1kJ/molepH: 7.4 T: 2°CAssay Description:CB1 competitive assay were performed in rat cerebellar membranes using [3H]WIN 55212-2 from Perkin-Elmer as a radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Rattus norvegicus (rat))
UniversitÀ

LigandPNGBDBM82140(4-methyl-N-({1-[2-(morpholin-4-yl)ethyl]-1H-indol-...)
Affinity DataKi:  15.7nM ΔG°:  -44.5kJ/molepH: 7.4 T: 2°CAssay Description:CB1 competitive assay were performed in rat cerebellar membranes using [3H]WIN 55212-2 from Perkin-Elmer as a radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Rattus norvegicus (rat))
UniversitÀ

LigandPNGBDBM82139(4-chloro-N-({1-[2-(morpholin-4-yl)ethyl]-1H-indol-...)
Affinity DataKi:  24.1nM ΔG°:  -43.5kJ/molepH: 7.4 T: 2°CAssay Description:CB1 competitive assay were performed in rat cerebellar membranes using [3H]WIN 55212-2 from Perkin-Elmer as a radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Rattus norvegicus (rat))
UniversitÀ

LigandPNGBDBM82137(4-methoxy-N-({1-[2-(morpholin-4-yl)ethyl]-1H-indol...)
Affinity DataKi:  42.6nM ΔG°:  -42.1kJ/molepH: 7.4 T: 2°CAssay Description:CB1 competitive assay were performed in rat cerebellar membranes using [3H]WIN 55212-2 from Perkin-Elmer as a radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Rattus norvegicus (rat))
UniversitÀ

LigandPNGBDBM82138(N-({1-[2-(morpholin-4-yl)ethyl]-1H-indol-3-yl}meth...)
Affinity DataKi:  49.4nM ΔG°:  -41.7kJ/molepH: 7.4 T: 2°CAssay Description:CB1 competitive assay were performed in rat cerebellar membranes using [3H]WIN 55212-2 from Perkin-Elmer as a radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Rattus norvegicus (rat))
UniversitÀ

LigandPNGBDBM82136(5-Substituted derivative, 6)
Affinity DataKi:  69.6nM ΔG°:  -40.9kJ/molepH: 7.4 T: 2°CAssay Description:CB1 competitive assay were performed in rat cerebellar membranes using [3H]WIN 55212-2 from Perkin-Elmer as a radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Rattus norvegicus (rat))
UniversitÀ

LigandPNGBDBM82132(5-Substituted derivative, 2)
Affinity DataKi:  74.6nM ΔG°:  -40.7kJ/molepH: 7.4 T: 2°CAssay Description:CB1 competitive assay were performed in rat cerebellar membranes using [3H]WIN 55212-2 from Perkin-Elmer as a radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Rattus norvegicus (rat))
UniversitÀ

LigandPNGBDBM82131(3-(Arylimino)-1-(2-morpholin-4-yl-ethyl)-1,3-dihyd...)
Affinity DataKi:  311nM ΔG°:  -37.1kJ/molepH: 7.4 T: 2°CAssay Description:CB1 competitive assay were performed in rat cerebellar membranes using [3H]WIN 55212-2 from Perkin-Elmer as a radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Rattus norvegicus (rat))
UniversitÀ

LigandPNGBDBM82133(5-Substituted derivative, 3)
Affinity DataKi:  390nM ΔG°:  -36.6kJ/molepH: 7.4 T: 2°CAssay Description:CB1 competitive assay were performed in rat cerebellar membranes using [3H]WIN 55212-2 from Perkin-Elmer as a radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Rattus norvegicus (rat))
UniversitÀ

LigandPNGBDBM82134(3-(Arylimino)-1-(2-morpholin-4-yl-ethyl)-1,3-dihyd...)
Affinity DataKi:  553nM ΔG°:  -35.7kJ/molepH: 7.4 T: 2°CAssay Description:CB1 competitive assay were performed in rat cerebellar membranes using [3H]WIN 55212-2 from Perkin-Elmer as a radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H1 receptor(Cavia porcellus (domestic guinea pig))
Universit£

Curated by ChEMBL
LigandPNGBDBM50368367(CHEMBL1202934)
Affinity DataIC50:  1.00E+3nMAssay Description:In vitro for histamine H1 receptor antagonist activity against histamine-induced contractions on isolated guinea pig ileumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H1 receptor(Cavia porcellus (domestic guinea pig))
Universit£

Curated by ChEMBL
LigandPNGBDBM50368376(CHEMBL1202938)
Affinity DataIC50:  1.20E+3nMAssay Description:In vitro for histamine H1 receptor antagonist activity against histamine-induced contractions on isolated guinea pig ileumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H1 receptor(Cavia porcellus (domestic guinea pig))
Universit£

Curated by ChEMBL
LigandPNGBDBM50002120(2-(3-Chloro-phenyl)-3-(3-dimethylamino-propyl)-thi...)
Affinity DataIC50:  2.20E+3nMAssay Description:In vitro for histamine H1 receptor antagonist activity against histamine-induced contractions on isolated guinea pig ileumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H1 receptor(Cavia porcellus (domestic guinea pig))
Universit£

Curated by ChEMBL
LigandPNGBDBM50368372(CHEMBL1202937)
Affinity DataIC50:  2.30E+3nMAssay Description:In vitro for histamine H1 receptor antagonist activity against histamine-induced contractions on isolated guinea pig ileumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H1 receptor(Cavia porcellus (domestic guinea pig))
Universit£

Curated by ChEMBL
LigandPNGBDBM50368366(CHEMBL1202933)
Affinity DataIC50:  3.10E+3nMAssay Description:In vitro for histamine H1 receptor antagonist activity against histamine-induced contractions on isolated guinea pig ileumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H1 receptor(Cavia porcellus (domestic guinea pig))
Universit£

Curated by ChEMBL
LigandPNGBDBM50368373(CHEMBL1202942)
Affinity DataIC50:  5.00E+3nMAssay Description:In vitro for histamine H1 receptor antagonist activity against histamine-induced contractions on isolated guinea pig ileumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H1 receptor(Cavia porcellus (domestic guinea pig))
Universit£

Curated by ChEMBL
LigandPNGBDBM50368365(CHEMBL1202936)
Affinity DataIC50:  2.00E+4nMAssay Description:In vitro for histamine H1 receptor antagonist activity against histamine-induced contractions on isolated guinea pig ileumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H1 receptor(Cavia porcellus (domestic guinea pig))
Universit£

Curated by ChEMBL
LigandPNGBDBM50002118(2-(4-Chloro-phenyl)-3-(3-dimethylamino-propyl)-thi...)
Affinity DataIC50:  2.10E+4nMAssay Description:In vitro for histamine H1 receptor antagonist activity against histamine-induced contractions on isolated guinea pig ileumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H1 receptor(Cavia porcellus (domestic guinea pig))
Universit£

Curated by ChEMBL
LigandPNGBDBM50368370(CHEMBL1202939)
Affinity DataIC50:  2.40E+4nMAssay Description:In vitro for histamine H1 receptor antagonist activity against histamine-induced contractions on isolated guinea pig ileumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H1 receptor(Cavia porcellus (domestic guinea pig))
Universit£

Curated by ChEMBL
LigandPNGBDBM50368368(CHEMBL1202941)
Affinity DataIC50:  2.50E+4nMAssay Description:In vitro for histamine H1 receptor antagonist activity against histamine-induced contractions on isolated guinea pig ileumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H1 receptor(Cavia porcellus (domestic guinea pig))
Universit£

Curated by ChEMBL
LigandPNGBDBM50368377(CHEMBL1202935)
Affinity DataIC50:  4.00E+4nMAssay Description:In vitro for histamine H1 receptor antagonist activity against histamine-induced contractions on isolated guinea pig ileumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H1 receptor(Cavia porcellus (domestic guinea pig))
Universit£

Curated by ChEMBL
LigandPNGBDBM50368371(CHEMBL1202932)
Affinity DataIC50:  6.00E+4nMAssay Description:In vitro for histamine H1 receptor antagonist activity against histamine-induced contractions on isolated guinea pig ileumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H1 receptor(Cavia porcellus (domestic guinea pig))
Universit£

Curated by ChEMBL
LigandPNGBDBM50368374(CHEMBL1202930)
Affinity DataIC50: >1.00E+5nMAssay Description:Compound was tested in vitro for histamine H1-antagonist activity against histamine-induced contractions on isolated guinea pig ileumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H1 receptor(Cavia porcellus (domestic guinea pig))
Universit£

Curated by ChEMBL
LigandPNGBDBM50368378(CHEMBL1202943)
Affinity DataIC50: >1.00E+5nMAssay Description:In vitro for histamine H1 receptor antagonist activity against histamine-induced contractions on isolated guinea pig ileumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H1 receptor(Cavia porcellus (domestic guinea pig))
Universit£

Curated by ChEMBL
LigandPNGBDBM50368369(CHEMBL1202940)
Affinity DataIC50: >1.00E+5nMAssay Description:In vitro for histamine H1 receptor antagonist activity against histamine-induced contractions on isolated guinea pig ileumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H1 receptor(Cavia porcellus (domestic guinea pig))
Universit£

Curated by ChEMBL
LigandPNGBDBM74475(3-[3-(dimethylamino)propyl]-2-(4-methoxyphenyl)-1,...)
Affinity DataIC50: >1.00E+5nMAssay Description:In vitro for histamine H1 receptor antagonist activity against histamine-induced contractions on isolated guinea pig ileumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H1 receptor(Cavia porcellus (domestic guinea pig))
Universit£

Curated by ChEMBL
LigandPNGBDBM50368375(CHEMBL1202944)
Affinity DataIC50: >1.00E+5nMAssay Description:In vitro for histamine H1 receptor antagonist activity against histamine-induced contractions on isolated guinea pig ileumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed