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Found 59 with Last Name = 'mclaren' and Initial = 'fm'
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50156071(3-Cyano-N-(2,5-diphenyl-2H-pyrazol-3-yl)-benzamide...)
Affinity DataKi:  250nMAssay Description:Displacement of [3H]-MPEP from human mGluR5More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50331975(1-(4-(2-chloro-4-fluorophenyl)piperazin-1-yl)-2-(p...)
Affinity DataKi:  2.37E+3nMAssay Description:Displacement of [3H]-MPEP from human mGluR5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50102319(11-(4-Methyl-piperazin-1-yl)-dibenzo[b,f][1,4]thia...)
Affinity DataIC50:  49nMAssay Description:Inhibition of spiropiperidone binding at dopamine receptor D2 of rat.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50001884(2-[4-(4-Methyl-benzyl)-piperazin-1-yl]-1-(2-methyl...)
Affinity DataIC50:  132nMAssay Description:Inhibition of spiropiperidone binding at dopamine receptor D2 of rat.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50102318(2-{2-[4-(5,5-Dioxo-5H-5lambda*6*-dibenzo[b,f][1,4]...)
Affinity DataIC50:  132nMAssay Description:Inhibition of spiropiperidone binding at dopamine receptor D2 of rat.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50102320(11-{4-[2-(2-Hydroxy-ethoxy)-ethyl]-piperazin-1-yl}...)
Affinity DataIC50:  166nMAssay Description:Inhibition of spiropiperidone binding at dopamine receptor D2 of rat.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50102326(11-[4-(3,4-Dimethoxy-butyl)-piperazin-1-yl]-dibenz...)
Affinity DataIC50:  293nMAssay Description:Inhibition of spiropiperidone binding at dopamine receptor D2 of rat.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50095890(2-[2-(4-Dibenzo[b,f][1,4]thiazepin-11-yl-1-piperaz...)
Affinity DataIC50:  330nMAssay Description:Inhibition of spiropiperidone binding at dopamine receptor D2 of rat.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50102321(11-[4-(Tetrahydro-furan-2-ylmethyl)-piperazin-1-yl...)
Affinity DataIC50:  417nMAssay Description:Inhibition of spiropiperidone binding at dopamine receptor D2 of rat.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50102323(2-{2-[4-(7-Fluoro-dibenzo[b,f][1,4]thiazepin-11-yl...)
Affinity DataIC50:  560nMAssay Description:Inhibition of spiropiperidone binding at dopamine receptor D2 of rat.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50102314(3-(4-Dibenzo[b,f][1,4]thiazepin-11-yl-piperazin-1-...)
Affinity DataIC50:  755nMAssay Description:Inhibition of spiropiperidone binding at dopamine receptor D2 of rat.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50102322(11-[4-(2,3-Dimethoxy-propyl)-piperazin-1-yl]-diben...)
Affinity DataIC50:  795nMAssay Description:Inhibition of spiropiperidone binding at dopamine receptor D2 of rat.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50102324(7-Fluoro-11-(4-methyl-piperazin-1-yl)-dibenzo[b,f]...)
Affinity DataIC50:  963nMAssay Description:Inhibition of spiropiperidone binding at dopamine receptor D2 of rat.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50102327(2-{2-[4-(3-Chloro-11H-dibenzo[b,e]azepin-6-yl)-pip...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of spiropiperidone binding at dopamine receptor D2 of rat.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50102315(2-(4-Dibenzo[b,f][1,4]thiazepin-11-yl-piperazin-1-...)
Affinity DataIC50:  1.33E+3nMAssay Description:Inhibition of spiropiperidone binding at dopamine receptor D2 of rat.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50102316(2-{2-[2-(4-Dibenzo[b,f][1,4]thiazepin-11-yl-pipera...)
Affinity DataIC50:  1.39E+3nMAssay Description:Inhibition of spiropiperidone binding at dopamine receptor D2 of rat.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50102317(2-(4-Dibenzo[b,f][1,4]thiazepin-11-yl-piperazin-1-...)
Affinity DataIC50:  1.64E+3nMAssay Description:Inhibition of spiropiperidone binding at dopamine receptor D2 of rat.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50102325(6-(4-Methyl-piperazin-1-yl)-11H-dibenzo[b,e]azepin...)
Affinity DataIC50:  2.70E+3nMAssay Description:Inhibition of spiropiperidone binding at dopamine receptor D2 of rat.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50331980(1-(4-(2,4-dichlorophenyl)piperazin-1-yl)-2-(thiazo...)
Affinity DataEC50:  290nMAssay Description:Positive allosteric modulation of human mGluR5 expressed in HEK293 cells assessed as Ca2+ influx by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50331981(2-(benzyloxy)-1-(4-(2,4-difluorophenyl)piperazin-1...)
Affinity DataEC50:  300nMAssay Description:Positive allosteric modulation of human mGluR5 expressed in HEK293 cells assessed as Ca2+ influx by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50331982(1-(4-(2,4-dichlorophenyl)piperazin-1-yl)-2-(pyridi...)
Affinity DataEC50:  310nMAssay Description:Positive allosteric modulation of human mGluR5 expressed in HEK293 cells assessed as Ca2+ influx by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50331983(1-(4-(2,4-dichlorophenyl)piperazin-1-yl)-2-(thioph...)
Affinity DataEC50: >310nMAssay Description:Positive allosteric modulation of human mGluR5 expressed in HEK293 cells assessed as Ca2+ influx by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50331984(2-(benzyloxy)-1-(4-(4-chlorophenyl)piperazin-1-yl)...)
Affinity DataEC50:  350nMAssay Description:Positive allosteric modulation of human mGluR5 expressed in HEK293 cells assessed as Ca2+ influx by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50331985(1-(4-(2-chloro-4-fluorophenyl)piperidin-1-yl)-2-(p...)
Affinity DataEC50:  370nMAssay Description:Positive allosteric modulation of human mGluR5 expressed in HEK293 cells assessed as Ca2+ influx by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50331986(1-(4-(2,4-dichlorophenyl)piperidin-1-yl)-2-(pyridi...)
Affinity DataEC50:  390nMAssay Description:Positive allosteric modulation of human mGluR5 expressed in HEK293 cells assessed as Ca2+ influx by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50331975(1-(4-(2-chloro-4-fluorophenyl)piperazin-1-yl)-2-(p...)
Affinity DataEC50:  550nMAssay Description:Positive allosteric modulation of human mGluR5 expressed in HEK293 cells assessed as Ca2+ influx by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50331987(2-(benzyloxy)-1-(4-(4-chloropyridin-2-yl)piperazin...)
Affinity DataEC50:  570nMAssay Description:Positive allosteric modulation of human mGluR5 expressed in HEK293 cells assessed as Ca2+ influx by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50331988(1-(4-(4-chloro-2-fluorophenyl)piperazin-1-yl)-2-(p...)
Affinity DataEC50:  600nMAssay Description:Positive allosteric modulation of human mGluR5 expressed in HEK293 cells assessed as Ca2+ influx by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50331989(1-(4-(4-chlorophenyl)piperidin-1-yl)-2-(pyridin-4-...)
Affinity DataEC50:  680nMAssay Description:Positive allosteric modulation of human mGluR5 expressed in HEK293 cells assessed as Ca2+ influx by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50331990(1-(4-(4-chlorophenyl)-4-fluoropiperidin-1-yl)-2-(p...)
Affinity DataEC50:  800nMAssay Description:Positive allosteric modulation of human mGluR5 expressed in HEK293 cells assessed as Ca2+ influx by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50331991(2-(benzyloxy)-1-(4-(2,4-dichlorophenyl)piperazin-1...)
Affinity DataEC50:  1.00E+3nMAssay Description:Positive allosteric modulation of human mGluR5 expressed in HEK293 cells assessed as Ca2+ influx by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50331992(1-(4-(2,4-dichlorophenyl)piperazin-1-yl)-2-(pyridi...)
Affinity DataEC50:  1.09E+3nMAssay Description:Positive allosteric modulation of human mGluR5 expressed in HEK293 cells assessed as Ca2+ influx by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50331993(2-(benzyloxy)-1-(4-(2-chlorophenyl)piperazin-1-yl)...)
Affinity DataEC50:  1.10E+3nMAssay Description:Positive allosteric modulation of human mGluR5 expressed in HEK293 cells assessed as Ca2+ influx by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50331994(2-(benzyloxy)-1-(4-(4-fluorophenyl)piperazin-1-yl)...)
Affinity DataEC50:  1.10E+3nMAssay Description:Positive allosteric modulation of human mGluR5 expressed in HEK293 cells assessed as Ca2+ influx by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50331995(1-(4-(2,4-dichlorophenyl)piperazin-1-yl)-2-(thiazo...)
Affinity DataEC50:  1.28E+3nMAssay Description:Positive allosteric modulation of human mGluR5 expressed in HEK293 cells assessed as Ca2+ influx by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50331996(1-(4-(4-chlorophenyl)piperazin-1-yl)-2-(pyridin-4-...)
Affinity DataEC50:  1.30E+3nMAssay Description:Positive allosteric modulation of human mGluR5 expressed in HEK293 cells assessed as Ca2+ influx by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50331997(1-(4-(4-chlorophenyl)-4-methylpiperidin-1-yl)-2-(p...)
Affinity DataEC50:  2.10E+3nMAssay Description:Positive allosteric modulation of human mGluR5 expressed in HEK293 cells assessed as Ca2+ influx by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50331998(1-(4-(2,4-dichlorophenyl)piperazin-1-yl)-2-(pyrimi...)
Affinity DataEC50:  2.80E+3nMAssay Description:Positive allosteric modulation of human mGluR5 expressed in HEK293 cells assessed as Ca2+ influx by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50331999(1-(4-(4-chloropyridin-2-yl)piperazin-1-yl)-2-(pyri...)
Affinity DataEC50:  4.20E+3nMAssay Description:Positive allosteric modulation of human mGluR5 expressed in HEK293 cells assessed as Ca2+ influx by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50332000(1-(4-(2,4-difluorophenyl)piperazin-1-yl)-2-(pyridi...)
Affinity DataEC50:  4.60E+3nMAssay Description:Positive allosteric modulation of human mGluR5 expressed in HEK293 cells assessed as Ca2+ influx by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50332001(1-(4-(2,4-dichlorophenyl)piperazin-1-yl)-2-(pyrazi...)
Affinity DataEC50:  5.20E+3nMAssay Description:Positive allosteric modulation of human mGluR5 expressed in HEK293 cells assessed as Ca2+ influx by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50332002(1-(4-(2,4-dichlorophenyl)-4-fluoropiperidin-1-yl)-...)
Affinity DataEC50:  6.60E+3nMAssay Description:Positive allosteric modulation of human mGluR5 expressed in HEK293 cells assessed as Ca2+ influx by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50332003(2-(benzyloxy)-1-(4-(3-chlorophenyl)piperazin-1-yl)...)
Affinity DataEC50:  6.70E+3nMAssay Description:Positive allosteric modulation of human mGluR5 expressed in HEK293 cells assessed as Ca2+ influx by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50332004(2-(benzyloxy)-1-(4-phenylpiperazin-1-yl)ethanone |...)
Affinity DataEC50:  7.10E+3nMAssay Description:Positive allosteric modulation of human mGluR5 expressed in HEK293 cells assessed as Ca2+ influx by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50332005(1-(4-(2,4-dichlorophenyl)piperazin-1-yl)-2-(thiazo...)
Affinity DataEC50:  1.03E+4nMAssay Description:Positive allosteric modulation of human mGluR5 expressed in HEK293 cells assessed as Ca2+ influx by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50332006(1-(4-(2,4-dichlorophenyl)piperazin-1-yl)-2-(pyrimi...)
Affinity DataEC50:  1.80E+4nMAssay Description:Positive allosteric modulation of human mGluR5 expressed in HEK293 cells assessed as Ca2+ influx by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50332007(2-(benzyloxy)-1-(4-(pyridin-4-yl)piperazin-1-yl)et...)
Affinity DataEC50: >2.50E+4nMAssay Description:Positive allosteric modulation of human mGluR5 expressed in HEK293 cells assessed as Ca2+ influx by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50331967(1-(4-(4-fluoro-2-chlorophenyl)piperidin-1-yl)-2-(p...)
Affinity DataEC50: >1.06E+4nMAssay Description:Positive allosteric modulation of human mGluR5 expressed in HEK293 cells assessed as Ca2+ influx by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50331968(1-(2-(benzyloxy)ethyl)-4-(2,4-dichlorophenyl)piper...)
Affinity DataEC50: >2.50E+4nMAssay Description:Positive allosteric modulation of human mGluR5 expressed in HEK293 cells assessed as Ca2+ influx by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50331969(1-(4-(2,4-dichlorophenyl)piperazin-1-yl)-4-(pyridi...)
Affinity DataEC50:  5.30E+3nMAssay Description:Positive allosteric modulation of human mGluR5 expressed in HEK293 cells assessed as Ca2+ influx by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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