Target5-hydroxytryptamine receptor 2C(Rattus norvegicus (Rat))
University Center For Pharmacy
Curated by ChEMBL
University Center For Pharmacy
Curated by ChEMBL
Affinity DataKi: 0.160nMAssay Description:The binding affinity of the compound at 5-hydroxytryptamine 2C receptor was determined using [3H]-mesulergineMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2C(Rattus norvegicus (Rat))
University Center For Pharmacy
Curated by ChEMBL
University Center For Pharmacy
Curated by ChEMBL
Affinity DataKi: 0.210nMAssay Description:The binding affinity of the compound at 5-hydroxytryptamine 2C receptor was determined using [3H]-mesulergineMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2C(Rattus norvegicus (Rat))
University Center For Pharmacy
Curated by ChEMBL
University Center For Pharmacy
Curated by ChEMBL
Affinity DataKi: 0.390nMAssay Description:The binding affinity of the compound at 5-hydroxytryptamine 2C receptor was determined using [3H]-mesulergineMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
University Center For Pharmacy
Curated by ChEMBL
University Center For Pharmacy
Curated by ChEMBL
Affinity DataKi: 0.550nMAssay Description:The binding affinity of the compound at 5-hydroxytryptamine 2A receptor was determined using [3H]-ketanserinMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
University Center For Pharmacy
Curated by ChEMBL
University Center For Pharmacy
Curated by ChEMBL
Affinity DataKi: 0.700nMAssay Description:The binding affinity of the compound at 5-hydroxytryptamine 2A receptor was determined using [3H]-ketanserinMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
University Center For Pharmacy
Curated by ChEMBL
University Center For Pharmacy
Curated by ChEMBL
Affinity DataKi: 0.75nMAssay Description:The binding affinity of the compound at 5-hydroxytryptamine 2A receptor was determined using [3H]-ketanserinMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2C(Rattus norvegicus (Rat))
University Center For Pharmacy
Curated by ChEMBL
University Center For Pharmacy
Curated by ChEMBL
Affinity DataKi: 1.40nMAssay Description:The binding affinity of the compound at 5-hydroxytryptamine 2C receptor was determined using [3H]-mesulergineMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
University Center For Pharmacy
Curated by ChEMBL
University Center For Pharmacy
Curated by ChEMBL
Affinity DataKi: 1.5nMAssay Description:The binding affinity of the compound at 5-hydroxytryptamine 2A receptor was determined using [3H]-ketanserinMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2C(Rattus norvegicus (Rat))
University Center For Pharmacy
Curated by ChEMBL
University Center For Pharmacy
Curated by ChEMBL
Affinity DataKi: 2nMAssay Description:The binding affinity of the compound at 5-hydroxytryptamine 2C receptor was determined using [3H]-mesulergineMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
University Center For Pharmacy
Curated by ChEMBL
University Center For Pharmacy
Curated by ChEMBL
Affinity DataKi: 2nMAssay Description:The binding affinity of the compound at 5-hydroxytryptamine 2A receptor was determined using [3H]-ketanserinMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2C(Rattus norvegicus (Rat))
University Center For Pharmacy
Curated by ChEMBL
University Center For Pharmacy
Curated by ChEMBL
Affinity DataKi: 5.5nMAssay Description:The binding affinity of the compound at 5-hydroxytryptamine 2C receptor was determined using [3H]-mesulergineMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
University Center For Pharmacy
Curated by ChEMBL
University Center For Pharmacy
Curated by ChEMBL
Affinity DataKi: 12nMAssay Description:The binding affinity of the compound at 5-hydroxytryptamine 2A receptor was determined using [3H]-ketanserinMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
University Center For Pharmacy
Curated by ChEMBL
University Center For Pharmacy
Curated by ChEMBL
Affinity DataKi: >18nMAssay Description:The binding affinity of the compound at the 5-hydroxytryptamine 1A receptor determined using [3H]-5-CTMore data for this Ligand-Target Pair
Affinity DataKi: >20nMAssay Description:The binding affinity of the compound at the Dopamine receptor D3 determined using [3H]-spiperoneMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
University Center For Pharmacy
Curated by ChEMBL
University Center For Pharmacy
Curated by ChEMBL
Affinity DataKi: 20nMAssay Description:The binding affinity of the compound at the Dopamine receptor D2 determined using [3H]-spiperoneMore data for this Ligand-Target Pair
Affinity DataKi: >25nMAssay Description:The binding affinity of the compound at the Dopamine receptor D4 determined using [3H]-YM-09151-2More data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
University Center For Pharmacy
Curated by ChEMBL
University Center For Pharmacy
Curated by ChEMBL
Affinity DataKi: 28nMAssay Description:The binding affinity of the compound at the Dopamine receptor D2 determined using [3H]-spiperoneMore data for this Ligand-Target Pair
Affinity DataKi: 47nMAssay Description:The binding affinity of the compound at the Dopamine receptor D4 determined using [3H]-YM-09151-2More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
University Center For Pharmacy
Curated by ChEMBL
University Center For Pharmacy
Curated by ChEMBL
Affinity DataKi: 70nMAssay Description:The binding affinity of the compound at 5-hydroxytryptamine 3 receptor was determined using [3H]-LY-278,584More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
University Center For Pharmacy
Curated by ChEMBL
University Center For Pharmacy
Curated by ChEMBL
Affinity DataKi: 80nMAssay Description:The binding affinity of the compound at 5-hydroxytryptamine 1D receptor was determined using [3H]-5-CTMore data for this Ligand-Target Pair
Affinity DataKi: 92nMAssay Description:The binding affinity of the compound at the Dopamine receptor D4 determined using [3H]-YM-09151-2More data for this Ligand-Target Pair
Affinity DataKi: 100nMAssay Description:The binding affinity of the compound at the Dopamine receptor D3 determined using [3H]-spiperoneMore data for this Ligand-Target Pair
Affinity DataKi: 160nMAssay Description:The binding affinity of the compound at the Dopamine receptor D4 determined using [3H]-YM-09151-2More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
University Center For Pharmacy
Curated by ChEMBL
University Center For Pharmacy
Curated by ChEMBL
Affinity DataKi: 255nMAssay Description:The binding affinity of the compound at the 5-hydroxytryptamine 1A receptor determined using [3H]-5-CTMore data for this Ligand-Target Pair
Affinity DataKi: 260nMAssay Description:The binding affinity of the compound at the Dopamine receptor D3 determined using [3H]-spiperoneMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
University Center For Pharmacy
Curated by ChEMBL
University Center For Pharmacy
Curated by ChEMBL
Affinity DataKi: 277nMAssay Description:The binding affinity of the compound at 5-hydroxytryptamine 2A receptor was determined using [3H]-ketanserinMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
University Center For Pharmacy
Curated by ChEMBL
University Center For Pharmacy
Curated by ChEMBL
Affinity DataKi: 345nMAssay Description:The binding affinity of the compound at the 5-hydroxytryptamine 1A receptor determined using [3H]-5-CTMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
University Center For Pharmacy
Curated by ChEMBL
University Center For Pharmacy
Curated by ChEMBL
Affinity DataKi: 460nMAssay Description:The binding affinity of the compound at the Dopamine receptor D2 determined using [3H]-spiperoneMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
University Center For Pharmacy
Curated by ChEMBL
University Center For Pharmacy
Curated by ChEMBL
Affinity DataKi: >500nMAssay Description:The binding affinity of the compound at the 5-hydroxytryptamine 1A receptor determined using [3H]-5-CTMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
University Center For Pharmacy
Curated by ChEMBL
University Center For Pharmacy
Curated by ChEMBL
Affinity DataKi: 800nMAssay Description:The binding affinity of the compound at the 5-hydroxytryptamine 1A receptor determined using [3H]-5-CTMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
University Center For Pharmacy
Curated by ChEMBL
University Center For Pharmacy
Curated by ChEMBL
Affinity DataKi: 1.00E+3nMAssay Description:The binding affinity of the compound at the Dopamine receptor D2 determined using [3H]-spiperoneMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
University Center For Pharmacy
Curated by ChEMBL
University Center For Pharmacy
Curated by ChEMBL
Affinity DataKi: 1.46E+3nMAssay Description:The binding affinity of the compound at the Dopamine receptor D2 determined using [3H]-spiperoneMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
University Center For Pharmacy
Curated by ChEMBL
University Center For Pharmacy
Curated by ChEMBL
Affinity DataKi: 1.47E+3nMAssay Description:The binding affinity of the compound at 5-hydroxytryptamine 1D receptor was determined using [3H]-5-CTMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
University Center For Pharmacy
Curated by ChEMBL
University Center For Pharmacy
Curated by ChEMBL
Affinity DataKi: 1.65E+3nMAssay Description:The binding affinity of the compound at 5-hydroxytryptamine 3 receptor was determined using [3H]-LY-278,584More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
University Center For Pharmacy
Curated by ChEMBL
University Center For Pharmacy
Curated by ChEMBL
Affinity DataKi: 2.90E+3nMAssay Description:The binding affinity of the compound at 5-hydroxytryptamine 3 receptor was determined using [3H]-LY-278,584More data for this Ligand-Target Pair
Affinity DataKi: 3.57E+3nMAssay Description:The binding affinity of the compound at the Dopamine receptor D3 determined using [3H]-spiperoneMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
University Center For Pharmacy
Curated by ChEMBL
University Center For Pharmacy
Curated by ChEMBL
Affinity DataKi: >5.00E+3nMAssay Description:The binding affinity of the compound at 5-hydroxytryptamine 3 receptor was determined using [3H]-LY-278,584More data for this Ligand-Target Pair
Affinity DataIC50: 0.360nMAssay Description:Antagonist activity at CCR1 in human THP1 cells assessed as inhibition of MIP-1alpha-induced chemotaxis after 2 hrs by fluorescence assayMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
University Of Groningen
Curated by ChEMBL
University Of Groningen
Curated by ChEMBL
Affinity DataIC50: 0.370nMAssay Description:In vitro affinity against 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT in rat hippocampusMore data for this Ligand-Target Pair
Affinity DataIC50: 0.520nMAssay Description:Antagonist activity at CCR1 in human THP1 cells assessed as inhibition of MIP-1alpha-induced chemotaxis after 2 hrs by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.630nMAssay Description:Displacement of [125I]MIP-1alpha from human recombinant CCR1 expressed in HEK293 cell membranes after 1.5 hrs by microbeta counting analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 0.890nMAssay Description:Displacement of [125I]MIP-1alpha from human recombinant CCR1 expressed in HEK293 cell membranes after 1.5 hrs by microbeta counting analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 0.920nMAssay Description:Antagonist activity at CCR1 in human THP1 cells assessed as inhibition of MIP-1alpha-induced chemotaxis after 2 hrs by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.10nMAssay Description:Antagonist activity at CCR1 in human THP1 cells assessed as inhibition of MIP-1alpha-induced chemotaxis after 2 hrs by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.30nMAssay Description:Displacement of [125I]MIP-1alpha from human recombinant CCR1 expressed in HEK293 cell membranes after 1.5 hrs by microbeta counting analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 1.30nMAssay Description:Antagonist activity at CCR1 in human THP1 cells assessed as inhibition of MIP-1alpha-induced chemotaxis after 2 hrs by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.40nMAssay Description:Antagonist activity at CCR1 in human THP1 cells assessed as inhibition of MIP-1alpha-induced chemotaxis after 2 hrs by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.40nMAssay Description:Antagonist activity at CCR1 in human THP1 cells assessed as inhibition of MIP-1alpha-induced chemotaxis after 2 hrs by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.40nMAssay Description:Displacement of [125I]MIP-1alpha from human recombinant CCR1 expressed in HEK293 cell membranes after 1.5 hrs by microbeta counting analysisMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
University Of Groningen
Curated by ChEMBL
University Of Groningen
Curated by ChEMBL
Affinity DataIC50: 1.55nMAssay Description:In vitro affinity against 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT in rat hippocampusMore data for this Ligand-Target Pair