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Found 1018 with Last Name = 'meyer-almes' and Initial = 'fj'
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
Max Planck Institute Of Molecular Physiology

Curated by ChEMBL
LigandPNGBDBM50178769((+/-)-6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-c...)
Affinity DataKi:  114nMAssay Description:Uncompetitive inhibition of His6-tagged SIRT1 (unknown origin) expressed in Escherichia coli BL21 (DE3) assessed as inhibition constant measured ever...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
Max Planck Institute Of Molecular Physiology

Curated by ChEMBL
LigandPNGBDBM50576050(CHEMBL4858009)
Affinity DataKi:  285nMAssay Description:Uncompetitive inhibition of His6-tagged SIRT1 (unknown origin) expressed in Escherichia coli BL21 (DE3) assessed as inhibition constant measured ever...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
Max Planck Institute Of Molecular Physiology

Curated by ChEMBL
LigandPNGBDBM50576055(CHEMBL4855963)
Affinity DataKi:  400nMAssay Description:Uncompetitive inhibition of His6-tagged SIRT1 (unknown origin) expressed in Escherichia coli BL21 (DE3) assessed as inhibition constant measured ever...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase-like amidohydrolase(Alcaligenes sp. (strain DSM 11172) (Bordetella sp....)
University Of G£Ttingen

Curated by ChEMBL
LigandPNGBDBM19130((2E,4E,6R)-7-[4-(dimethylamino)phenyl]-N-hydroxy-4...)
Affinity DataKi:  700nMAssay Description:Displacement of Atto700-HA from Bordetella/Alcaligenes strain FB188 HDAH by fluorescence anisotropyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase-like amidohydrolase(Alcaligenes sp. (strain DSM 11172) (Bordetella sp....)
University Of G£Ttingen

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)
Affinity DataKi:  1.00E+3nMAssay Description:Binding affinity to Bordetella/Alcaligenes strain FB188 HDAC by FRET assayMore data for this Ligand-Target Pair
TargetHistone deacetylase-like amidohydrolase(Alcaligenes sp. (strain DSM 11172) (Bordetella sp....)
University Of G£Ttingen

Curated by ChEMBL
LigandPNGBDBM50293703(2-ethyl-3-methoxy-6-methyl-5-(11-oxododecyl)cycloh...)
Affinity DataKi:  1.10E+3nMAssay Description:Displacement of Atto700-HA from Bordetella/Alcaligenes strain FB188 HDAH by fluorescence anisotropyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase-like amidohydrolase(Alcaligenes sp. (strain DSM 11172) (Bordetella sp....)
University Of G£Ttingen

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)
Affinity DataKi:  1.30E+3nMAssay Description:Displacement of Atto700-HA from Bordetella/Alcaligenes strain FB188 HDAH by fluorescence anisotropyMore data for this Ligand-Target Pair
TargetHistone deacetylase-like amidohydrolase(Alcaligenes sp. (strain DSM 11172) (Bordetella sp....)
University Of G£Ttingen

Curated by ChEMBL
LigandPNGBDBM50293704(1,1,1-trifluoro-7-(1H-naphtho[2,3-d]imidazol-2-yl)...)
Affinity DataKi:  1.40E+3nMAssay Description:Displacement of Atto700-HA from Bordetella/Alcaligenes strain FB188 HDAH by fluorescence anisotropyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase-like amidohydrolase(Alcaligenes sp. (strain DSM 11172) (Bordetella sp....)
University Of G£Ttingen

Curated by ChEMBL
LigandPNGBDBM50293705(((2R,3S,4S,5R,6S)-6-((2R,3R,4S,5S,6R)-4,5-dihydrox...)
Affinity DataKi:  2.00E+3nMAssay Description:Binding affinity to Bordetella/Alcaligenes strain FB188 HDAC by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 7(Homo sapiens (Human))
University Of Applied Sciences Darmstadt

Curated by ChEMBL
LigandPNGBDBM50361254(CHEMBL1934896)
Affinity DataKi:  2.50E+3nMAssay Description:Inhibitory potency against Varicella zoster virus ribonucleotide reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase-like amidohydrolase(Alcaligenes sp. (strain DSM 11172) (Bordetella sp....)
University Of G£Ttingen

Curated by ChEMBL
LigandPNGBDBM50293702(11-(3-pentyloxiran-2-yl)undec-9-ynoic acid | CHEMB...)
Affinity DataKi:  4.30E+3nMAssay Description:Binding affinity to Bordetella/Alcaligenes strain FB188 HDAC by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
University Of Applied Sciences Darmstadt

Curated by ChEMBL
LigandPNGBDBM50361254(CHEMBL1934896)
Affinity DataKi:  7.00E+3nMAssay Description:Inhibition of human HDAC1 using Boc-Lys(Ac)-AMC as substrate preincubated for 30 mins followed by substrate addition measured after 60 mins by trypsi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
University Of Applied Sciences Darmstadt

Curated by ChEMBL
LigandPNGBDBM50361254(CHEMBL1934896)
Affinity DataKi:  8.40E+3nMAssay Description:Binding affinity at 5-hydroxytryptamine 4 receptor in rat striatum by [3H]GR-113808 displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase-like amidohydrolase(Alcaligenes sp. (strain DSM 11172) (Bordetella sp....)
University Of G£Ttingen

Curated by ChEMBL
LigandPNGBDBM50238632((6S,9S,12S,14aR)-6-((S)-sec-Butyl)-9-(1-methoxy-1H...)
Affinity DataKi:  9.20E+3nMAssay Description:Displacement of Atto700-HA from Bordetella/Alcaligenes strain FB188 HDAH by fluorescence anisotropyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase-like amidohydrolase(Alcaligenes sp. (strain DSM 11172) (Bordetella sp....)
University Of G£Ttingen

Curated by ChEMBL
LigandPNGBDBM50293705(((2R,3S,4S,5R,6S)-6-((2R,3R,4S,5S,6R)-4,5-dihydrox...)
Affinity DataKi:  1.00E+4nMAssay Description:Displacement of Atto700-HA from Bordetella/Alcaligenes strain FB188 HDAH by fluorescence anisotropyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 5(Homo sapiens (Human))
University Of Applied Sciences Darmstadt

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)
Affinity DataKi:  1.20E+4nMAssay Description:Inhibition of human HDAC5 using Boc-Lys(trifluoroacetyl)-AMC as substrate preincubated for 30 mins followed by substrate addition measured after 60 m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 5(Homo sapiens (Human))
University Of Applied Sciences Darmstadt

Curated by ChEMBL
LigandPNGBDBM50361248(CHEMBL1934890)
Affinity DataKi:  1.30E+4nMAssay Description:Inhibition of human HDAC5 using Boc-Lys(trifluoroacetyl)-AMC as substrate preincubated for 30 mins followed by substrate addition measured after 60 m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
University Of Applied Sciences Darmstadt

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)
Affinity DataKi:  1.40E+4nMAssay Description:Inhibition of human HDAC4 using Boc-Lys(trifluoroacetyl)-AMC as substrate preincubated for 30 mins followed by substrate addition measured after 60 m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
University Of Applied Sciences Darmstadt

Curated by ChEMBL
LigandPNGBDBM50361254(CHEMBL1934896)
Affinity DataKi:  2.00E+4nMAssay Description:Inhibitory potency against Varicella zoster virus ribonucleotide reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase-like amidohydrolase(Alcaligenes sp. (strain DSM 11172) (Bordetella sp....)
University Of G£Ttingen

Curated by ChEMBL
LigandPNGBDBM50293702(11-(3-pentyloxiran-2-yl)undec-9-ynoic acid | CHEMB...)
Affinity DataKi:  2.00E+4nMAssay Description:Displacement of Atto700-HA from Bordetella/Alcaligenes strain FB188 HDAH by fluorescence anisotropyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
University Of Applied Sciences Darmstadt

Curated by ChEMBL
LigandPNGBDBM50235706(CHEMBL4080874)
Affinity DataKi: >5.00E+4nMAssay Description:Inhibition of human HDAC8 using Boc-Lys(trifluoroacetyl)-AMC as substrate preincubated for 30 mins followed by substrate addition measured after 60 m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
University Of Applied Sciences Darmstadt

Curated by ChEMBL
LigandPNGBDBM50235706(CHEMBL4080874)
Affinity DataKi: >5.00E+4nMAssay Description:Inhibition of human HDAC6 using Boc-Lys(Ac)-AMC as substrate preincubated for 30 mins followed by substrate addition measured after 60 mins by trypsi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 5(Homo sapiens (Human))
University Of Applied Sciences Darmstadt

Curated by ChEMBL
LigandPNGBDBM50361250(CHEMBL1934892)
Affinity DataKi: >5.00E+4nMAssay Description:Inhibition of human HDAC5 using Boc-Lys(trifluoroacetyl)-AMC as substrate preincubated for 30 mins followed by substrate addition measured after 60 m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 5(Homo sapiens (Human))
University Of Applied Sciences Darmstadt

Curated by ChEMBL
LigandPNGBDBM50235706(CHEMBL4080874)
Affinity DataKi: >5.00E+4nMAssay Description:Binding affinity at 5-hydroxytryptamine 4 receptor in rat striatum by [3H]GR-113808 displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 5(Homo sapiens (Human))
University Of Applied Sciences Darmstadt

Curated by ChEMBL
LigandPNGBDBM50361252(CHEMBL1934894)
Affinity DataKi: >5.00E+4nMAssay Description:Binding affinity at 5-hydroxytryptamine 3 receptor in rat entorhinal cortex by [3H]BRL-43694 displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 5(Homo sapiens (Human))
University Of Applied Sciences Darmstadt

Curated by ChEMBL
LigandPNGBDBM50361258(CHEMBL1934900)
Affinity DataKi: >5.00E+4nMAssay Description:Binding affinity at 5-hydroxytryptamine 3 receptor in rat entorhinal cortex by [3H]BRL-43694 displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 5(Homo sapiens (Human))
University Of Applied Sciences Darmstadt

Curated by ChEMBL
LigandPNGBDBM50361266(CHEMBL1934908)
Affinity DataKi: >5.00E+4nMAssay Description:Inhibition of human HDAC5 using Boc-Lys(trifluoroacetyl)-AMC as substrate preincubated for 30 mins followed by substrate addition measured after 60 m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
University Of Applied Sciences Darmstadt

Curated by ChEMBL
LigandPNGBDBM50235701(CHEMBL4098910)
Affinity DataKi: >5.00E+4nMAssay Description:Inhibition of human HDAC4 using Boc-Lys(trifluoroacetyl)-AMC as substrate preincubated for 30 mins followed by substrate addition measured after 60 m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
University Of Applied Sciences Darmstadt

Curated by ChEMBL
LigandPNGBDBM50361249(CHEMBL1934891)
Affinity DataKi: >5.00E+4nMAssay Description:Inhibition of human HDAC4 using Boc-Lys(trifluoroacetyl)-AMC as substrate preincubated for 30 mins followed by substrate addition measured after 60 m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 5(Homo sapiens (Human))
University Of Applied Sciences Darmstadt

Curated by ChEMBL
LigandPNGBDBM50235701(CHEMBL4098910)
Affinity DataKi: >5.00E+4nMAssay Description:Binding affinity at 5-hydroxytryptamine 4 receptor in rat striatum by [3H]GR-113808 displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
University Of Applied Sciences Darmstadt

Curated by ChEMBL
LigandPNGBDBM50235702(CHEMBL4104197)
Affinity DataKi: >5.00E+4nMAssay Description:Inhibition of human HDAC8 using Boc-Lys(trifluoroacetyl)-AMC as substrate preincubated for 30 mins followed by substrate addition measured after 60 m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
University Of Applied Sciences Darmstadt

Curated by ChEMBL
LigandPNGBDBM50235705(CHEMBL4093113)
Affinity DataKi: >5.00E+4nMAssay Description:Binding affinity at 5-hydroxytryptamine 3 receptor in rat entorhinal cortex by [3H]BRL-43694 displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
University Of Applied Sciences Darmstadt

Curated by ChEMBL
LigandPNGBDBM50361254(CHEMBL1934896)
Affinity DataKi: >5.00E+4nMAssay Description:Binding affinity at 5-hydroxytryptamine 3 receptor in rat entorhinal cortex by [3H]BRL-43694 displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
University Of Applied Sciences Darmstadt

Curated by ChEMBL
LigandPNGBDBM50361266(CHEMBL1934908)
Affinity DataKi: >5.00E+4nMAssay Description:Binding affinity at 5-hydroxytryptamine 4 receptor in rat striatum by [3H]GR-113808 displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
University Of Applied Sciences Darmstadt

Curated by ChEMBL
LigandPNGBDBM50361267(CHEMBL1934909)
Affinity DataKi: >5.00E+4nMAssay Description:Binding affinity at 5-hydroxytryptamine 4 receptor in rat striatum by [3H]GR-113808 displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
University Of Applied Sciences Darmstadt

Curated by ChEMBL
LigandPNGBDBM50361265(CHEMBL1934907)
Affinity DataKi: >5.00E+4nMAssay Description:Inhibition of human HDAC4 using Boc-Lys(trifluoroacetyl)-AMC as substrate preincubated for 30 mins followed by substrate addition measured after 60 m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 5(Homo sapiens (Human))
University Of Applied Sciences Darmstadt

Curated by ChEMBL
LigandPNGBDBM50361253(CHEMBL1934895)
Affinity DataKi: >5.00E+4nMAssay Description:Inhibition of human HDAC5 using Boc-Lys(trifluoroacetyl)-AMC as substrate preincubated for 30 mins followed by substrate addition measured after 60 m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 5(Homo sapiens (Human))
University Of Applied Sciences Darmstadt

Curated by ChEMBL
LigandPNGBDBM50235708(CHEMBL4079958)
Affinity DataKi: >5.00E+4nMAssay Description:Binding affinity at 5-hydroxytryptamine 3 receptor in rat entorhinal cortex by [3H]BRL-43694 displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 5(Homo sapiens (Human))
University Of Applied Sciences Darmstadt

Curated by ChEMBL
LigandPNGBDBM50235702(CHEMBL4104197)
Affinity DataKi: >5.00E+4nMAssay Description:Inhibition of human HDAC5 using Boc-Lys(trifluoroacetyl)-AMC as substrate preincubated for 30 mins followed by substrate addition measured after 60 m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 5(Homo sapiens (Human))
University Of Applied Sciences Darmstadt

Curated by ChEMBL
LigandPNGBDBM50235705(CHEMBL4093113)
Affinity DataKi: >5.00E+4nMAssay Description:Inhibition of human HDAC5 using Boc-Lys(trifluoroacetyl)-AMC as substrate preincubated for 30 mins followed by substrate addition measured after 60 m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
University Of Applied Sciences Darmstadt

Curated by ChEMBL
LigandPNGBDBM50235707(CHEMBL4095542)
Affinity DataKi: >5.00E+4nMAssay Description:Binding affinity at 5-hydroxytryptamine 3 receptor in rat entorhinal cortex by [3H]BRL-43694 displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 5(Homo sapiens (Human))
University Of Applied Sciences Darmstadt

Curated by ChEMBL
LigandPNGBDBM50361264(CHEMBL1934906)
Affinity DataKi: >5.00E+4nMAssay Description:Binding affinity at 5-hydroxytryptamine 3 receptor in rat entorhinal cortex by [3H]BRL-43694 displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
University Of Applied Sciences Darmstadt

Curated by ChEMBL
LigandPNGBDBM50361248(CHEMBL1934890)
Affinity DataKi: >5.00E+4nMAssay Description:Binding affinity at 5-hydroxytryptamine 3 receptor in rat entorhinal cortex by [3H]BRL-43694 displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 5(Homo sapiens (Human))
University Of Applied Sciences Darmstadt

Curated by ChEMBL
LigandPNGBDBM50235703(CHEMBL4066515)
Affinity DataKi: >5.00E+4nMAssay Description:Inhibition of human HDAC5 using Boc-Lys(trifluoroacetyl)-AMC as substrate preincubated for 30 mins followed by substrate addition measured after 60 m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 5(Homo sapiens (Human))
University Of Applied Sciences Darmstadt

Curated by ChEMBL
LigandPNGBDBM50235707(CHEMBL4095542)
Affinity DataKi: >5.00E+4nMAssay Description:Inhibition of human HDAC5 using Boc-Lys(trifluoroacetyl)-AMC as substrate preincubated for 30 mins followed by substrate addition measured after 60 m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 5(Homo sapiens (Human))
University Of Applied Sciences Darmstadt

Curated by ChEMBL
LigandPNGBDBM50361251(CHEMBL1934893)
Affinity DataKi: >5.00E+4nMAssay Description:Binding affinity at 5-hydroxytryptamine 3 receptor in rat entorhinal cortex by [3H]BRL-43694 displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 5(Homo sapiens (Human))
University Of Applied Sciences Darmstadt

Curated by ChEMBL
LigandPNGBDBM50361268(CHEMBL1934910)
Affinity DataKi: >5.00E+4nMAssay Description:Binding affinity at 5-hydroxytryptamine 3 receptor in rat entorhinal cortex by [3H]BRL-43694 displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 5(Homo sapiens (Human))
University Of Applied Sciences Darmstadt

Curated by ChEMBL
LigandPNGBDBM50361262(CHEMBL1934904)
Affinity DataKi: >5.00E+4nMAssay Description:Inhibition of human HDAC5 using Boc-Lys(trifluoroacetyl)-AMC as substrate preincubated for 30 mins followed by substrate addition measured after 60 m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 5(Homo sapiens (Human))
University Of Applied Sciences Darmstadt

Curated by ChEMBL
LigandPNGBDBM50361255(CHEMBL1934897)
Affinity DataKi: >5.00E+4nMAssay Description:Inhibition of human HDAC5 using Boc-Lys(trifluoroacetyl)-AMC as substrate preincubated for 30 mins followed by substrate addition measured after 60 m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 5(Homo sapiens (Human))
University Of Applied Sciences Darmstadt

Curated by ChEMBL
LigandPNGBDBM50361249(CHEMBL1934891)
Affinity DataKi: >5.00E+4nMAssay Description:Binding affinity at 5-hydroxytryptamine 3 receptor in rat entorhinal cortex by [3H]BRL-43694 displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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