Compile Data Set for Download or QSAR
maximum 50k data
Found 1327 with Last Name = 'michoud' and Initial = 'c'
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50205477((Z)-2-((1R,2S)-2-phenylcyclopropylamino)-5-(quinol...)
Affinity DataKi:  20nMAssay Description:Inhibition of CDK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50205472((5Z)-5-(quinolin-6-ylmethylidene)-2-[(thiophen-2-y...)
Affinity DataKi:  35nMAssay Description:Inhibition of CDK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50205468((Z)-2-amino-5-(quinolin-6-ylmethylene)thiazol-4(5H...)
Affinity DataKi:  150nMAssay Description:Inhibition of CDK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50205477((Z)-2-((1R,2S)-2-phenylcyclopropylamino)-5-(quinol...)
Affinity DataKi:  220nMAssay Description:Inhibition of ERKMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C delta type(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50205472((5Z)-5-(quinolin-6-ylmethylidene)-2-[(thiophen-2-y...)
Affinity DataKi:  320nMAssay Description:Inhibition of PKCdMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50205472((5Z)-5-(quinolin-6-ylmethylidene)-2-[(thiophen-2-y...)
Affinity DataKi:  340nMAssay Description:Inhibition of CDK2More data for this Ligand-Target Pair
TargetProtein kinase C delta type(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50205477((Z)-2-((1R,2S)-2-phenylcyclopropylamino)-5-(quinol...)
Affinity DataKi:  480nMAssay Description:Inhibition of PKCdMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50205472((5Z)-5-(quinolin-6-ylmethylidene)-2-[(thiophen-2-y...)
Affinity DataKi:  500nMAssay Description:Inhibition of GSKp1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C delta type(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50205468((Z)-2-amino-5-(quinolin-6-ylmethylene)thiazol-4(5H...)
Affinity DataKi:  1.70E+3nMAssay Description:Inhibition of PKCdMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibosomal protein S6 kinase alpha-3(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50205472((5Z)-5-(quinolin-6-ylmethylidene)-2-[(thiophen-2-y...)
Affinity DataKi: >2.00E+3nMAssay Description:Inhibition of PKAP1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50205472((5Z)-5-(quinolin-6-ylmethylidene)-2-[(thiophen-2-y...)
Affinity DataKi:  2.00E+3nMAssay Description:Inhibition of ERKMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-B receptor 3(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50205477((Z)-2-((1R,2S)-2-phenylcyclopropylamino)-5-(quinol...)
Affinity DataKi: >2.00E+3nMAssay Description:Inhibition of EPHB3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50205468((Z)-2-amino-5-(quinolin-6-ylmethylene)thiazol-4(5H...)
Affinity DataKi:  2.00E+3nMAssay Description:Inhibition of CDK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 4(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50205468((Z)-2-amino-5-(quinolin-6-ylmethylene)thiazol-4(5H...)
Affinity DataKi: >2.00E+3nMAssay Description:Inhibition of CDK4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-B receptor 3(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50205472((5Z)-5-(quinolin-6-ylmethylidene)-2-[(thiophen-2-y...)
Affinity DataKi: >2.00E+3nMAssay Description:Inhibition of EPHB3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Fyn(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50205477((Z)-2-((1R,2S)-2-phenylcyclopropylamino)-5-(quinol...)
Affinity DataKi: >2.00E+3nMAssay Description:Inhibition of FYNMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50205477((Z)-2-((1R,2S)-2-phenylcyclopropylamino)-5-(quinol...)
Affinity DataKi: >2.00E+3nMAssay Description:Inhibition of CDK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50205468((Z)-2-amino-5-(quinolin-6-ylmethylene)thiazol-4(5H...)
Affinity DataKi: >2.00E+3nMAssay Description:Inhibition of ERKMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibosomal protein S6 kinase alpha-3(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50205468((Z)-2-amino-5-(quinolin-6-ylmethylene)thiazol-4(5H...)
Affinity DataKi: >2.00E+3nMAssay Description:Inhibition of PKAP1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-B receptor 3(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50205468((Z)-2-amino-5-(quinolin-6-ylmethylene)thiazol-4(5H...)
Affinity DataKi: >2.00E+3nMAssay Description:Inhibition of EPHB3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibosomal protein S6 kinase alpha-3(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50205477((Z)-2-((1R,2S)-2-phenylcyclopropylamino)-5-(quinol...)
Affinity DataKi: >2.00E+3nMAssay Description:Inhibition of PKAP1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Fyn(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50205472((5Z)-5-(quinolin-6-ylmethylidene)-2-[(thiophen-2-y...)
Affinity DataKi: >2.00E+3nMAssay Description:Inhibition of FYNMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 4(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50205477((Z)-2-((1R,2S)-2-phenylcyclopropylamino)-5-(quinol...)
Affinity DataKi: >2.00E+3nMAssay Description:Inhibition of CDK4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 4(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50205472((5Z)-5-(quinolin-6-ylmethylidene)-2-[(thiophen-2-y...)
Affinity DataKi: >2.00E+3nMAssay Description:Inhibition of CDK4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C alpha type(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50205477((Z)-2-((1R,2S)-2-phenylcyclopropylamino)-5-(quinol...)
Affinity DataKi: >2.00E+3nMAssay Description:Inhibition of PKCaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAC-alpha/RAC-beta/RAC-gamma serine/threonine-protein kinase(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50205477((Z)-2-((1R,2S)-2-phenylcyclopropylamino)-5-(quinol...)
Affinity DataKi: >2.00E+3nMAssay Description:Inhibition of AKTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50205477((Z)-2-((1R,2S)-2-phenylcyclopropylamino)-5-(quinol...)
Affinity DataKi: >2.00E+3nMAssay Description:Inhibition of GSKp1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50205468((Z)-2-amino-5-(quinolin-6-ylmethylene)thiazol-4(5H...)
Affinity DataKi: >2.00E+3nMAssay Description:Inhibition of GSKp1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAC-alpha/RAC-beta/RAC-gamma serine/threonine-protein kinase(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50205468((Z)-2-amino-5-(quinolin-6-ylmethylene)thiazol-4(5H...)
Affinity DataKi: >2.00E+3nMAssay Description:Inhibition of AKTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C alpha type(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50205468((Z)-2-amino-5-(quinolin-6-ylmethylene)thiazol-4(5H...)
Affinity DataKi: >2.00E+3nMAssay Description:Inhibition of PKCaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C alpha type(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50205472((5Z)-5-(quinolin-6-ylmethylidene)-2-[(thiophen-2-y...)
Affinity DataKi: >2.00E+3nMAssay Description:Inhibition of PKCaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Fyn(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50205468((Z)-2-amino-5-(quinolin-6-ylmethylene)thiazol-4(5H...)
Affinity DataKi: >2.00E+3nMAssay Description:Inhibition of FYNMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAC-alpha/RAC-beta/RAC-gamma serine/threonine-protein kinase(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50205472((5Z)-5-(quinolin-6-ylmethylidene)-2-[(thiophen-2-y...)
Affinity DataKi: >2.00E+3nMAssay Description:Inhibition of AKTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase XIAP [124-240](Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM243099((S)—N—((S)-5-(4-Acetylbenzoyl)-1-((6-bro...)
Affinity DataIC50:  1nMpH: 7.5 T: 2°CAssay Description:Ten nanomolar of 6× Histidine-tagged BIR2 domain, corresponding to amino acids 124-240 of XIAP, or BIR3 domain, corresponding to amino acids 241-356 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase XIAP [124-240](Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM242611((2S)-N-(1-((6-bromo-2- methoxynaphthalen-1-yl)meth...)
Affinity DataIC50:  4.99nMpH: 7.5 T: 2°CAssay Description:Ten nanomolar of 6× Histidine-tagged BIR2 domain, corresponding to amino acids 124-240 of XIAP, or BIR3 domain, corresponding to amino acids 241-356 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase XIAP(Homo sapiens (Human))
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50441819(CHEMBL2436209 | US10053431, 89b)
Affinity DataIC50:  5nMAssay Description:Displacement of AVPIAQKSEK (epsilon-biotin)-OH from 6xhistidine-thrombin-TEV-tagged XIAP BIR2 domain (124 to 240) (unknown origin) after 45 mins by T...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase XIAP [124-240](Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM243177(US10053431, 75c)
Affinity DataIC50:  5nMpH: 7.5 T: 2°CAssay Description:Ten nanomolar of 6× Histidine-tagged BIR2 domain, corresponding to amino acids 124-240 of XIAP, or BIR3 domain, corresponding to amino acids 241-356 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase XIAP [124-240](Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM243181(US10053431, 76d)
Affinity DataIC50:  5nMpH: 7.5 T: 2°CAssay Description:Ten nanomolar of 6× Histidine-tagged BIR2 domain, corresponding to amino acids 124-240 of XIAP, or BIR3 domain, corresponding to amino acids 241-356 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase XIAP [124-240](Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM50441819(CHEMBL2436209 | US10053431, 89b)
Affinity DataIC50:  5nMpH: 7.5 T: 2°CAssay Description:Ten nanomolar of 6× Histidine-tagged BIR2 domain, corresponding to amino acids 124-240 of XIAP, or BIR3 domain, corresponding to amino acids 241-356 ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase XIAP [124-240](Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM242641((S)-N-((S)-1-((5-bromo-2- methoxynaphthalen-1-yl)m...)
Affinity DataIC50:  5.11nMpH: 7.5 T: 2°CAssay Description:Ten nanomolar of 6× Histidine-tagged BIR2 domain, corresponding to amino acids 124-240 of XIAP, or BIR3 domain, corresponding to amino acids 241-356 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase XIAP [124-240](Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM242603((S)-N-((S)-5-(4-aminobenzoyl)-1-((6- bromo-2-metho...)
Affinity DataIC50:  5.68nMpH: 7.5 T: 2°CAssay Description:Ten nanomolar of 6× Histidine-tagged BIR2 domain, corresponding to amino acids 124-240 of XIAP, or BIR3 domain, corresponding to amino acids 241-356 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase XIAP [124-240](Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM50441834(CHEMBL2436330 | US10053431, 91a)
Affinity DataIC50:  6nMpH: 7.5 T: 2°CAssay Description:Ten nanomolar of 6× Histidine-tagged BIR2 domain, corresponding to amino acids 124-240 of XIAP, or BIR3 domain, corresponding to amino acids 241-356 ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase XIAP [124-240](Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM242682((S)—N—((S)-1-((5-Bromo-2-methoxynaphthal...)
Affinity DataIC50:  6nMpH: 7.5 T: 2°CAssay Description:Ten nanomolar of 6× Histidine-tagged BIR2 domain, corresponding to amino acids 124-240 of XIAP, or BIR3 domain, corresponding to amino acids 241-356 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase XIAP [124-240](Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM243119(US10053431, 89a)
Affinity DataIC50:  6nMpH: 7.5 T: 2°CAssay Description:Ten nanomolar of 6× Histidine-tagged BIR2 domain, corresponding to amino acids 124-240 of XIAP, or BIR3 domain, corresponding to amino acids 241-356 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase XIAP [124-240](Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM242606((S)—N—((S)-5-(4-aminobenzoyl)-1-((6-brom...)
Affinity DataIC50:  6nMpH: 7.5 T: 2°CAssay Description:Ten nanomolar of 6× Histidine-tagged BIR2 domain, corresponding to amino acids 124-240 of XIAP, or BIR3 domain, corresponding to amino acids 241-356 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase XIAP [124-240](Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM50441816(CHEMBL2436208 | US10053431, 41)
Affinity DataIC50:  6nMpH: 7.5 T: 2°CAssay Description:Ten nanomolar of 6× Histidine-tagged BIR2 domain, corresponding to amino acids 124-240 of XIAP, or BIR3 domain, corresponding to amino acids 241-356 ...More data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase XIAP(Homo sapiens (Human))
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50441818(CHEMBL2436213 | US10053431, 75d)
Affinity DataIC50:  6nMAssay Description:Displacement of AVPIAQKSEK (epsilon-biotin)-OH from 6xhistidine-thrombin-TEV-tagged XIAP BIR2 domain (124 to 240) (unknown origin) after 45 mins by T...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase XIAP(Homo sapiens (Human))
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50441831(CHEMBL2436212 | US10053431, 91c)
Affinity DataIC50:  6nMAssay Description:Displacement of AVPIAQKSEK (epsilon-biotin)-OH from 6xhistidine-thrombin-TEV-tagged XIAP BIR2 domain (124 to 240) (unknown origin) after 45 mins by T...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase XIAP(Homo sapiens (Human))
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50441816(CHEMBL2436208 | US10053431, 41)
Affinity DataIC50:  6nMAssay Description:Displacement of AVPIAQKSEK (epsilon-biotin)-OH from 6xhistidine-thrombin-TEV-tagged XIAP BIR2 domain (124 to 240) (unknown origin) after 45 mins by T...More data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase XIAP(Homo sapiens (Human))
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50441832(CHEMBL2436205 | US10053431, 90d)
Affinity DataIC50:  6nMAssay Description:Displacement of AVPIAQKSEK (epsilon-biotin)-OH from 6xhistidine-thrombin-TEV-tagged XIAP BIR2 domain (124 to 240) (unknown origin) after 45 mins by T...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Displayed 1 to 50 (of 1327 total ) | Next | Last >>
Jump to: