Affinity DataKi: 0.640nMAssay Description:Displacement of [125I]SS-14 from human SST3 receptor expressed in CHO cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 1.40nMAssay Description:Inhibition of stromelysin-1 (MMP-3).More data for this Ligand-Target Pair
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataKi: 1.40nMAssay Description:Inhibitory activity of the compound against specific binding of [125I]-MIP-1 alpha to human CCR5 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 1.70nMAssay Description:Binding affinity to human SST3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 2.10nMAssay Description:Inhibition of gelatinase-A (MMP-2).More data for this Ligand-Target Pair
Affinity DataKi: 2.10nMAssay Description:Inhibition of gelatinase-A (MMP-2).More data for this Ligand-Target Pair
Affinity DataKi: 2.30nMAssay Description:Inhibition of stromelysin-1 (MMP-3).More data for this Ligand-Target Pair
Affinity DataKi: 2.40nMAssay Description:Binding affinity to human NK2 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 2.40nMAssay Description:Binding affinity to human NK3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 2.5nMAssay Description:Inhibition of stromelysin-1 (MMP-3).More data for this Ligand-Target Pair
Affinity DataKi: 4.5nMAssay Description:Inhibition of stromelysin-1 (MMP-3).More data for this Ligand-Target Pair
Affinity DataKi: 4.80nMAssay Description:Inhibition of gelatinase-A (MMP-2).More data for this Ligand-Target Pair
Affinity DataKi: 5.5nMAssay Description:Inhibition of stromelysin-1 (MMP-3).More data for this Ligand-Target Pair
Affinity DataKi: 5.70nMAssay Description:Inhibition of stromelysin-1 (MMP-3).More data for this Ligand-Target Pair
Affinity DataKi: 6.10nMAssay Description:Inhibition of gelatinase-A (MMP-2).More data for this Ligand-Target Pair
Affinity DataKi: 7.30nMAssay Description:Inhibition of gelatinase-A (MMP-2).More data for this Ligand-Target Pair
Affinity DataKi: 12nMAssay Description:Inhibition of gelatinase-A (MMP-2).More data for this Ligand-Target Pair
Affinity DataKi: 13nMAssay Description:Inhibition of stromelysin-1 (MMP-3).More data for this Ligand-Target Pair
Affinity DataKi: 16nMAssay Description:Inhibition of stromelysin-1 (MMP-3).More data for this Ligand-Target Pair
Affinity DataKi: 17nMAssay Description:Inhibition of stromelysin-1 (MMP-3).More data for this Ligand-Target Pair
Affinity DataKi: 19nMAssay Description:Inhibition of gelatinase-A (MMP-2)More data for this Ligand-Target Pair
Affinity DataKi: 20nMAssay Description:Inhibition of gelatinase-A (MMP-2).More data for this Ligand-Target Pair
Affinity DataKi: 24nMAssay Description:Inhibition of stromelysin-1 (MMP-3).More data for this Ligand-Target Pair
Affinity DataKi: 26nMAssay Description:Inhibition of stromelysin-1 (MMP-3).More data for this Ligand-Target Pair
Affinity DataKi: 26nMAssay Description:Inhibition of gelatinase-A (MMP-2).More data for this Ligand-Target Pair
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataKi: 29nMAssay Description:Displacement of [125I]MCP1 from human CCR2 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 30nMAssay Description:Inhibition of stromelysin-1 (MMP-3).More data for this Ligand-Target Pair
Affinity DataKi: 50nMAssay Description:Inhibition of stromelysin-1 (MMP-3).More data for this Ligand-Target Pair
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataKi: 50nMAssay Description:Displacement of [125I]MCP1 from human CCR2 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 54nMAssay Description:Inhibition of stromelysin-1 (MMP-3).More data for this Ligand-Target Pair
Affinity DataKi: 56nMAssay Description:Inhibition of stromelysin-1 (MMP-3).More data for this Ligand-Target Pair
Affinity DataKi: 62nMAssay Description:Inhibition of stromelysin-1 (MMP-3).More data for this Ligand-Target Pair
Affinity DataKi: 63nMAssay Description:Inhibition of stromelysin-1 (MMP-3).More data for this Ligand-Target Pair
Affinity DataKi: 70nMAssay Description:Inhibition of stromelysin-1 (MMP-3).More data for this Ligand-Target Pair
Affinity DataKi: 130nMAssay Description:Inhibition of stromelysin-1 (MMP-3).More data for this Ligand-Target Pair
Affinity DataKi: 130nMAssay Description:Inhibition of gelatinase-A (MMP-2).More data for this Ligand-Target Pair
Affinity DataKi: 170nMAssay Description:Inhibition of stromelysin-1 (MMP-3).More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataKi: 400nMAssay Description:Binding affinity against hERG Voltage-gated potassium channel subunit Kv11.1More data for this Ligand-Target Pair
Affinity DataKi: 410nMAssay Description:Inhibition of stromelysin-1 (MMP-3).More data for this Ligand-Target Pair
Affinity DataKi: 440nMAssay Description:Inhibition of stromelysin-1 (MMP-3).More data for this Ligand-Target Pair
Affinity DataKi: 470nMAssay Description:Inhibition of stromelysin-1 (MMP-3).More data for this Ligand-Target Pair
Affinity DataKi: 520nMAssay Description:Inhibition of stromelysin-1 (MMP-3).More data for this Ligand-Target Pair
Affinity DataKi: 540nMAssay Description:Inhibition of stromelysin-1 (MMP-3)More data for this Ligand-Target Pair
Affinity DataKi: 570nMAssay Description:Inhibition of gelatinase-A (MMP-2).More data for this Ligand-Target Pair
Affinity DataKi: 670nMAssay Description:Inhibition of stromelysin-1 (MMP-3).More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataKi: 1.00E+3nMAssay Description:Binding affinity against hERG Voltage-gated potassium channel subunit Kv11.1More data for this Ligand-Target Pair
Affinity DataKi: 1.30E+3nMAssay Description:Inhibition of gelatinase-A (MMP-2).More data for this Ligand-Target Pair
Affinity DataKi: 1.50E+3nMAssay Description:Inhibition of stromelysin-1 (MMP-3).More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataKi: 2.10E+3nMAssay Description:Binding affinity against hERG Voltage-gated potassium channel subunit Kv11.1More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataKi: 2.30E+3nMAssay Description:Binding affinity against hERG Voltage-gated potassium channel subunit Kv11.1More data for this Ligand-Target Pair