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Found 296 with Last Name = 'mony' and Initial = 'l'
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
University Of Strasburg

Curated by ChEMBL
LigandPNGBDBM50007674((+)-erythro 4-[2-(4-Benzyl-piperidin-1-yl)-1-hydro...)
Affinity DataKi:  11nMAssay Description:Displacement of [3H]ifenprodil from rat brain membrane NR2B receptorMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
University Of Strasburg

Curated by ChEMBL
LigandPNGBDBM50377833(CHEMBL413998)
Affinity DataKi:  58nMAssay Description:Displacement of [3H]ifenprodil from rat brain membrane NR2B receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
University Of Strasburg

Curated by ChEMBL
LigandPNGBDBM50377825(CHEMBL258032)
Affinity DataKi:  62nMAssay Description:Displacement of [3H]ifenprodil from rat brain membrane NR2B receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
University Of Strasburg

Curated by ChEMBL
LigandPNGBDBM50377831(CHEMBL255697)
Affinity DataKi:  97nMAssay Description:Displacement of [3H]ifenprodil from rat brain membrane NR2B receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
University Of Strasburg

Curated by ChEMBL
LigandPNGBDBM50377831(CHEMBL255697)
Affinity DataKi:  97nMAssay Description:Displacement of [3H]ifenprodil from rat brain membrane NR2B receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
University Of Strasburg

Curated by ChEMBL
LigandPNGBDBM50377834(CHEMBL401882)
Affinity DataKi:  107nMAssay Description:Displacement of [3H]ifenprodil from rat brain membrane NR2B receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
University Of Strasburg

Curated by ChEMBL
LigandPNGBDBM50377828(CHEMBL257783)
Affinity DataKi:  141nMAssay Description:Displacement of [3H]ifenprodil from rat brain membrane NR2B receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
University Of Strasburg

Curated by ChEMBL
LigandPNGBDBM50377827(CHEMBL257989)
Affinity DataKi:  200nMAssay Description:Displacement of [3H]ifenprodil from rat brain membrane NR2B receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
University Of Strasburg

Curated by ChEMBL
LigandPNGBDBM50377826(CHEMBL402979)
Affinity DataKi:  245nMAssay Description:Displacement of [3H]ifenprodil from rat brain membrane NR2B receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
University Of Strasburg

Curated by ChEMBL
LigandPNGBDBM50377829(CHEMBL255895)
Affinity DataKi:  248nMAssay Description:Displacement of [3H]ifenprodil from rat brain membrane NR2B receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
University Of Strasburg

Curated by ChEMBL
LigandPNGBDBM50377832(CHEMBL401688)
Affinity DataKi:  493nMAssay Description:Displacement of [3H]ifenprodil from rat brain membrane NR2B receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
University Of Strasburg

Curated by ChEMBL
LigandPNGBDBM50377830(CHEMBL401806)
Affinity DataKi:  527nMAssay Description:Displacement of [3H]ifenprodil from rat brain membrane NR2B receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
University Of Strasburg

Curated by ChEMBL
LigandPNGBDBM50377835(CHEMBL256083)
Affinity DataKi:  679nMAssay Description:Displacement of [3H]ifenprodil from rat brain membrane NR2B receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2B(Homo sapiens (Human))
University Of Strasburg

Curated by ChEMBL
LigandPNGBDBM50007674((+)-erythro 4-[2-(4-Benzyl-piperidin-1-yl)-1-hydro...)
Affinity DataIC50:  110nMAssay Description:Inhibition of NR1/NR2B receptor expressed in xenopus oocytes assessed as effect on L-glutamate and glycine-induced current responseMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 1/2B(Homo sapiens (Human))
University Of Strasburg

Curated by ChEMBL
LigandPNGBDBM50083351((+/-)-[2-(4-benzylpiperidino)-1-(4-hydroxyphenyl)-...)
Affinity DataIC50:  190nMAssay Description:Antagonist activity at wild type NR1/NR2B receptor expressed in Xenopus oocytes assessed as inhibition of agonist-induced current amplitude by two-el...More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 1/2B(Homo sapiens (Human))
University Of Strasburg

Curated by ChEMBL
LigandPNGBDBM50482632(CHEMBL1223786)
Affinity DataIC50:  1.65E+3nMAssay Description:Antagonist activity at wild type NR1/NR2B receptor expressed in Xenopus oocytes assessed as inhibition of agonist-induced current amplitude by two-el...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2B(Homo sapiens (Human))
University Of Strasburg

Curated by ChEMBL
LigandPNGBDBM50482631(CHEMBL1223841)
Affinity DataIC50:  1.80E+3nMAssay Description:Antagonist activity at wild type NR1/NR2B receptor expressed in Xenopus oocytes assessed as inhibition of agonist-induced current amplitude by two-el...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2B(Homo sapiens (Human))
University Of Strasburg

Curated by ChEMBL
LigandPNGBDBM50482630(CHEMBL1223722)
Affinity DataIC50:  2.70E+3nMAssay Description:Antagonist activity at wild type NR1/NR2B receptor expressed in Xenopus oocytes assessed as inhibition of agonist-induced current amplitude by two-el...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2B(Homo sapiens (Human))
University Of Strasburg

Curated by ChEMBL
LigandPNGBDBM50482628(CHEMBL1223842)
Affinity DataIC50:  1.10E+4nMAssay Description:Antagonist activity at wild type NR1/NR2B receptor expressed in Xenopus oocytes assessed as inhibition of agonist-induced current amplitude by two-el...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2B(Homo sapiens (Human))
University Of Strasburg

Curated by ChEMBL
LigandPNGBDBM50482629(CHEMBL1223845)
Affinity DataIC50:  1.30E+4nMAssay Description:Antagonist activity at wild type NR1/NR2B receptor expressed in Xenopus oocytes assessed as inhibition of agonist-induced current amplitude by two-el...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2B(Homo sapiens (Human))
University Of Strasburg

Curated by ChEMBL
LigandPNGBDBM50377832(CHEMBL401688)
Affinity DataIC50:  1.40E+4nMAssay Description:Inhibition of NR1/NR2B receptor expressed in xenopus oocytes assessed as effect on L-glutamate and glycine-induced current responseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2A(Homo sapiens (Human))
University Of Strasburg

Curated by ChEMBL
LigandPNGBDBM50377826(CHEMBL402979)
Affinity DataIC50:  1.60E+4nMAssay Description:Inhibition of NR1/NR2A receptor expressed in xenopus oocytes assessed as effect on L-glutamate and glycine-induced current responseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2B(Homo sapiens (Human))
University Of Strasburg

Curated by ChEMBL
LigandPNGBDBM50377826(CHEMBL402979)
Affinity DataIC50:  1.60E+4nMAssay Description:Inhibition of NR1/NR2B receptor expressed in xenopus oocytes assessed as effect on L-glutamate and glycine-induced current responseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2B(Homo sapiens (Human))
University Of Strasburg

Curated by ChEMBL
LigandPNGBDBM50377830(CHEMBL401806)
Affinity DataIC50:  7.00E+4nMAssay Description:Inhibition of NR1/NR2B receptor expressed in xenopus oocytes assessed as effect on L-glutamate and glycine-induced current responseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2B(Homo sapiens (Human))
University Of Strasburg

Curated by ChEMBL
LigandPNGBDBM50377832(CHEMBL401688)
Affinity DataIC50:  2.30E+5nMAssay Description:Inhibition of N-terminal domain truncated NR1/NR2B receptor expressed in xenopus oocytes assessed as effect on L-glutamate and glycine-induced curren...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2B(Homo sapiens (Human))
University Of Strasburg

Curated by ChEMBL
LigandPNGBDBM50377826(CHEMBL402979)
Affinity DataIC50:  5.70E+5nMAssay Description:Inhibition of N-terminal domain truncated NR1/NR2B receptor expressed in xenopus oocytes assessed as effect on L-glutamate and glycine-induced curren...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2A(Rattus norvegicus (Rat))
University of Paris

Curated by ChEMBL
LigandPNGBDBM50446782(CHEMBL3114672)
Affinity DataIC50:  1.10E+6nMAssay Description:Agonist activity at mGlu4 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as increase in intracellular calcium...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2B(RAT)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50446782(CHEMBL3114672)
Affinity DataIC50:  2.30E+6nMAssay Description:Antagonist activity at rat GluN1a/mouse GluN2B receptors expressed in Xenopus laevis oocytes assessed as inhibition of L-glutamate/glucine induced cu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2A(Homo sapiens (Human))
University Of Strasburg

Curated by ChEMBL
LigandPNGBDBM50377826(CHEMBL402979)
Affinity DataEC50: >1.00E+5nMAssay Description:Activity at NR1/NR2A receptor expressed in xenopus oocytes assessed as effect on L-glutamate and glycine-induced current responseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2A(Homo sapiens (Human))
University Of Strasburg

Curated by ChEMBL
LigandPNGBDBM50377832(CHEMBL401688)
Affinity DataEC50: >1.00E+5nMAssay Description:Activity at NR1/NR2A receptor expressed in xenopus oocytes assessed as effect on L-glutamate and glycine-induced current responseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2A(Homo sapiens (Human))
University Of Strasburg

Curated by ChEMBL
LigandPNGBDBM50377830(CHEMBL401806)
Affinity DataEC50: >1.00E+5nMAssay Description:Activity at NR1/NR2A receptor expressed in xenopus oocytes assessed as effect on L-glutamate and glycine-induced current responseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 7(Homo sapiens (Human))
University of Paris

Curated by ChEMBL
LigandPNGBDBM50255339(CHEMBL4060360)
Affinity DataEC50:  6.90E+4nMAssay Description:Agonist activity at mGlu7 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as [3H]inositol phosphate accumulati...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 7(Homo sapiens (Human))
University of Paris

Curated by ChEMBL
LigandPNGBDBM50446782(CHEMBL3114672)
Affinity DataEC50:  5.30E+4nMAssay Description:Agonist activity at mGlu7 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as [3H]inositol phosphate accumulati...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 7(Homo sapiens (Human))
University of Paris

Curated by ChEMBL
LigandPNGBDBM50255292(CHEMBL4061423)
Affinity DataEC50:  4.18E+5nMAssay Description:Agonist activity at mGlu7 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as [3H]inositol phosphate accumulati...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
University of Paris

Curated by ChEMBL
LigandPNGBDBM50314793((S)-3-amino-3-carboxypropyl-2'-carboxyethyl phosph...)
Affinity DataEC50:  5.94E+3nMAssay Description:Agonist activity at mGlu4 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as increase in intracellular calcium...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
University of Paris

Curated by ChEMBL
LigandPNGBDBM50255293(CHEMBL4094636)
Affinity DataEC50:  5.90E+4nMAssay Description:Agonist activity at mGlu4 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as increase in intracellular calcium...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
University of Paris

Curated by ChEMBL
LigandPNGBDBM50255387(CHEMBL4086929)
Affinity DataEC50:  6.50E+3nMAssay Description:Agonist activity at mGlu4 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as increase in intracellular calcium...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
University of Paris

Curated by ChEMBL
LigandPNGBDBM50255388(CHEMBL4093492)
Affinity DataEC50:  600nMAssay Description:Agonist activity at mGlu4 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as increase in intracellular calcium...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
University of Paris

Curated by ChEMBL
LigandPNGBDBM50255389(CHEMBL4072781)
Affinity DataEC50:  1.00E+3nMAssay Description:Agonist activity at mGlu4 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as increase in intracellular calcium...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
University of Paris

Curated by ChEMBL
LigandPNGBDBM50255403(CHEMBL4101241)
Affinity DataEC50:  3.30E+3nMAssay Description:Agonist activity at mGlu4 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as increase in intracellular calcium...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 7(Homo sapiens (Human))
University of Paris

Curated by ChEMBL
LigandPNGBDBM50255290(CHEMBL4093081)
Affinity DataEC50:  2.95E+5nMAssay Description:Agonist activity at mGlu7 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as increase in intracellular calcium...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 7(Homo sapiens (Human))
University of Paris

Curated by ChEMBL
LigandPNGBDBM50255391(CHEMBL4082813)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at mGlu7 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as increase in intracellular calcium...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 7(Homo sapiens (Human))
University of Paris

Curated by ChEMBL
LigandPNGBDBM50255346(CHEMBL4085327)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at mGlu7 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as increase in intracellular calcium...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 7(Homo sapiens (Human))
University of Paris

Curated by ChEMBL
LigandPNGBDBM50255348(CHEMBL4085558)
Affinity DataEC50:  1.00E+5nMAssay Description:Agonist activity at mGlu7 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as increase in intracellular calcium...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 7(Homo sapiens (Human))
University of Paris

Curated by ChEMBL
LigandPNGBDBM50255334(CHEMBL4094241)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at mGlu7 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as increase in intracellular calcium...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 7(Homo sapiens (Human))
University of Paris

Curated by ChEMBL
LigandPNGBDBM50255407(CHEMBL4077705)
Affinity DataEC50:  5.12E+4nMAssay Description:Agonist activity at mGlu7 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as increase in intracellular calcium...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 7(Homo sapiens (Human))
University of Paris

Curated by ChEMBL
LigandPNGBDBM50255414(CHEMBL4096644)
Affinity DataEC50:  5.38E+4nMAssay Description:Agonist activity at mGlu7 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as increase in intracellular calcium...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 7(Homo sapiens (Human))
University of Paris

Curated by ChEMBL
LigandPNGBDBM50255415(CHEMBL4078629)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at mGlu7 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as increase in intracellular calcium...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 7(Homo sapiens (Human))
University of Paris

Curated by ChEMBL
LigandPNGBDBM50255369(CHEMBL4061016)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at mGlu7 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as increase in intracellular calcium...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 8(Homo sapiens (Human))
University of Paris

Curated by ChEMBL
LigandPNGBDBM50255292(CHEMBL4061423)
Affinity DataEC50:  380nMAssay Description:Agonist activity at mGlu8 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as increase in intracellular calcium...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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