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Found 130 with Last Name = 'moriya' and Initial = 'r'
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50249779(3-[(4S,5S)-4-(4-Fluorophenyl)-4-(6-fluoro-3-pyridy...)
Affinity DataKi:  0.800nMAssay Description:Displacement of [125I]PYY from human recombinant neuropeptide Y5 receptor expressed in mouse LMtk- cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50249739(2-[(5S)-4,4-Bis(4-fluorophenyl)-5-methyl-4,5-dihyd...)
Affinity DataKi:  1nMAssay Description:Displacement of [125I]PYY from human recombinant neuropeptide Y5 receptor expressed in mouse LMtk- cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50249806(4-[(4S,5S)-4-(4-Fluorophenyl)-4-(6-fluoro-3-pyridy...)
Affinity DataKi:  1nMAssay Description:Displacement of [125I]PYY from human recombinant neuropeptide Y5 receptor expressed in mouse LMtk- cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50249777(2-{(4S,5S)-4-(4-Fluorophenyl)-5-methyl-4-[6-(methy...)
Affinity DataKi:  1.10nMAssay Description:Displacement of [125I]PYY from human recombinant neuropeptide Y5 receptor expressed in mouse LMtk- cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50249758(2-[(4S,5S)-4-(4-Fluorophenyl)-4-(6-fluoro-3-pyridy...)
Affinity DataKi:  1.30nMAssay Description:Displacement of [125I]PYY from human recombinant neuropeptide Y5 receptor expressed in mouse LMtk- cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50249833(6-[(4S,5S)-4-(4-Fluorophenyl)-4-(6-fluoro-3-pyridy...)
Affinity DataKi:  1.40nMAssay Description:Displacement of [125I]PYY from human recombinant neuropeptide Y5 receptor expressed in mouse LMtk- cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50249775(2-[(4R,5S)-4-(4-Fluorophenyl)-4-(6-fluoro-3-pyridy...)
Affinity DataKi:  1.60nMAssay Description:Displacement of [125I]PYY from human recombinant neuropeptide Y5 receptor expressed in mouse LMtk- cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50249830(4-Chloro-2-[(4S,5S)-4-(4-fluorophenyl)-4-(6-fluoro...)
Affinity DataKi:  1.80nMAssay Description:Displacement of [125I]PYY from human recombinant neuropeptide Y5 receptor expressed in mouse LMtk- cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50249757(2-[(5S)-4,4-Bis(4-fluorophenyl)-5-methyl-4,5-dihyd...)
Affinity DataKi:  1.90nMAssay Description:Displacement of [125I]PYY from human recombinant neuropeptide Y5 receptor expressed in mouse LMtk- cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50249737(2-(4,4-bis(4-fluorophenyl)-4,5-dihydro-1H-imidazol...)
Affinity DataKi:  2nMAssay Description:Displacement of [125I]PYY from human recombinant neuropeptide Y5 receptor expressed in mouse LMtk- cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50249865(2-Fluoro-5-[(4S,5S)-4-(4-fluorophenyl)-5-methyl-2-...)
Affinity DataKi:  2nMAssay Description:Displacement of [125I]PYY from human recombinant neuropeptide Y5 receptor expressed in mouse LMtk- cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50249832(2-[(4S,5S)-4-(4-Fluorophenyl)-4-(6-fluoro-3-pyridy...)
Affinity DataKi:  2.20nMAssay Description:Displacement of [125I]PYY from human recombinant neuropeptide Y5 receptor expressed in mouse LMtk- cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50249869(3-oxo-N-(5-phenylpyrazin-2-yl)-3H-spiro[isobenzofu...)
Affinity DataKi:  2.40nMAssay Description:Displacement of [125I]PYY from human recombinant neuropeptide Y5 receptor expressed in mouse LMtk- cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50249829(2-[(4S,5S)-4-(4-Fluorophenyl)-4-(6-fluoro-3-pyridy...)
Affinity DataKi:  2.5nMAssay Description:Displacement of [125I]PYY from human recombinant neuropeptide Y5 receptor expressed in mouse LMtk- cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50249803(2-Fluoro-5-{(4S,5S)-4-(4-fluorophenyl)-5-methyl-2-...)
Affinity DataKi:  2.5nMAssay Description:Displacement of [125I]PYY from human recombinant neuropeptide Y5 receptor expressed in mouse LMtk- cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50249754(2-[(5S)-5-Ethyl-4,4-bis(4-fluorophenyl)-4,5-dihydr...)
Affinity DataKi:  2.60nMAssay Description:Displacement of [125I]PYY from human recombinant neuropeptide Y5 receptor expressed in mouse LMtk- cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50249756(2-[(5R)-4,4-Bis(4-fluorophenyl)-5-(hydroxymethyl)-...)
Affinity DataKi:  3nMAssay Description:Displacement of [125I]PYY from human recombinant neuropeptide Y5 receptor expressed in mouse LMtk- cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50249776(2-[(5S)-4,4-Bis(6-fluoro-3-pyridyl)-5-methyl-4,5-d...)
Affinity DataKi:  3.10nMAssay Description:Displacement of [125I]PYY from human recombinant neuropeptide Y5 receptor expressed in mouse LMtk- cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50249804(5-[(4S,5S)-4-(4-Fluorophenyl)-4-(6-fluoro-3-pyridy...)
Affinity DataKi:  3.20nMAssay Description:Displacement of [125I]PYY from human recombinant neuropeptide Y5 receptor expressed in mouse LMtk- cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50249807(2-[(4S,5S)-4-(4-Fluorophenyl)-4-(6-fluoro-3-pyridy...)
Affinity DataKi:  3.60nMAssay Description:Displacement of [125I]PYY from human recombinant neuropeptide Y5 receptor expressed in mouse LMtk- cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50249866(2-Fluoro-5-[(4S,5S)-4-(4-fluorophenyl)-5-methyl-2-...)
Affinity DataKi:  4.10nMAssay Description:Displacement of [125I]PYY from human recombinant neuropeptide Y5 receptor expressed in mouse LMtk- cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50249738(2-(4,4-bis(4-fluorophenyl)-4,5-dihydro-1H-imidazol...)
Affinity DataKi:  4.30nMAssay Description:Displacement of [125I]PYY from human recombinant neuropeptide Y5 receptor expressed in mouse LMtk- cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50249831(2-((4S,5S)-4-(4-fluorophenyl)-4-(6-fluoropyridin-3...)
Affinity DataKi:  5.10nMAssay Description:Displacement of [125I]PYY from human recombinant neuropeptide Y5 receptor expressed in mouse LMtk- cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50249805(6-[(4S,5S)-4-(4-Fluorophenyl)-4-(6-fluoro-3-pyridy...)
Affinity DataKi:  5.90nMAssay Description:Displacement of [125I]PYY from human recombinant neuropeptide Y5 receptor expressed in mouse LMtk- cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50249755(2-[(5S)-4,4-Bis(4-fluorophenyl)-5-propyl-4,5-dihyd...)
Affinity DataKi:  8.60nMAssay Description:Displacement of [125I]PYY from human recombinant neuropeptide Y5 receptor expressed in mouse LMtk- cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM86733(5,5-DIMETHYL-2-(2,3,4,9-TETRAHYDRO-3,3-DIMETHYL-1O...)
Affinity DataKi:  33nMAssay Description:Displacement of [125I]PYY from human recombinant neuropeptide Y5 receptor expressed in mouse LMtk- cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50249778(2-[(4S,5S)-4-(4-Fluorophenyl)-5-methyl-4-(6-oxo-1,...)
Affinity DataKi:  145nMAssay Description:Displacement of [125I]PYY from human recombinant neuropeptide Y5 receptor expressed in mouse LMtk- cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50249740(2-[(5R)-4,4-Bis(4-fluorophenyl)-5-methyl-4,5-dihyd...)
Affinity DataKi:  300nMAssay Description:Displacement of [125I]PYY from human recombinant neuropeptide Y5 receptor expressed in mouse LMtk- cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50249758(2-[(4S,5S)-4-(4-Fluorophenyl)-4-(6-fluoro-3-pyridy...)
Affinity DataIC50:  2nMAssay Description:Antagonist activity at human recombinant neuropeptide Y5 receptor expressed in CHO-K1 cells coexpressing Gqi5 assessed as inhibition of NPY-induced i...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50297070(CHEMBL560474 | N-(2-cyclopropyl-3-methylimidazo[1,...)
Affinity DataIC50:  2nMAssay Description:Displacement of [125I]MCH from human MCH1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50297062(4-(5-chloropyridin-2-yl)-N-(2-cyclopropyl-3-methyl...)
Affinity DataIC50:  2.20nMAssay Description:Displacement of [125I]MCH from human MCH1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50297073(CHEMBL564106 | N-(2-cyclopropyl-3-methylimidazo[1,...)
Affinity DataIC50:  2.5nMAssay Description:Displacement of [125I]MCH from human MCH1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM30177(2-aminobenzimidazole-based compound, 25)
Affinity DataIC50:  2.70nMpH: 7.4 T: 2°CAssay Description:Compounds were evaluated for their binding affinity to the membranes of CHO-K1 cells expressing human MCH1R (hMCH1R) in a competition binding assay w...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM30172(2-aminobenzimidazole-based compound, 20)
Affinity DataIC50:  3.10nMpH: 7.4 T: 2°CAssay Description:Compounds were evaluated for their binding affinity to the membranes of CHO-K1 cells expressing human MCH1R (hMCH1R) in a competition binding assay w...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50297061(CHEMBL551934 | N-(2-cyclopropyl-3-methylimidazo[1,...)
Affinity DataIC50:  3.30nMAssay Description:Displacement of [125I]MCH from human MCH1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50297059(CHEMBL561134 | N-(2-cyclopropyl-3-methylimidazo[1,...)
Affinity DataIC50:  3.5nMAssay Description:Displacement of [125I]MCH from human MCH1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50297071(CHEMBL562136 | N-(2-cyclopropyl-3-methylimidazo[1,...)
Affinity DataIC50:  4nMAssay Description:Displacement of [125I]MCH from human MCH1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50297067(CHEMBL565105 | N-(2-cyclopropyl-3-methylimidazo[1,...)
Affinity DataIC50:  4nMAssay Description:Displacement of [125I]MCH from human MCH1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM30164(2-aminobenzimidazole-based compound, 12)
Affinity DataIC50:  4nM EC50:  22nMpH: 7.4 T: 2°CAssay Description:Compounds were evaluated for their binding affinity to the membranes of CHO-K1 cells expressing human MCH1R (hMCH1R) in a competition binding assay w...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50297068(CHEMBL551470 | N-(2-cyclopropyl-3-methylimidazo[1,...)
Affinity DataIC50:  4.40nMAssay Description:Displacement of [125I]MCH from human MCH1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50297042(CHEMBL557731 | N-(2-methylimidazo[1,2-a]pyridin-6-...)
Affinity DataIC50:  4.60nMAssay Description:Displacement of [125I]MCH from human MCH1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50297052(CHEMBL563725 | N-(2-cyclopropyl-3-methylimidazo[1,...)
Affinity DataIC50:  4.80nMAssay Description:Displacement of [125I]MCH from human MCH1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50297064(CHEMBL563728 | N-(2-cyclopropyl-3-methylimidazo[1,...)
Affinity DataIC50:  4.80nMAssay Description:Displacement of [125I]MCH from human MCH1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50297041(CHEMBL557664 | N-(2-isopropylimidazo[1,2-a]pyridin...)
Affinity DataIC50:  5.40nMAssay Description:Displacement of [125I]MCH from human MCH1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50297063(CHEMBL559680 | N-(2-cyclopropyl-3-methylimidazo[1,...)
Affinity DataIC50:  5.40nMAssay Description:Displacement of [125I]MCH from human MCH1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM30174(2-aminobenzimidazole-based compound, 22)
Affinity DataIC50:  5.5nMpH: 7.4 T: 2°CAssay Description:Compounds were evaluated for their binding affinity to the membranes of CHO-K1 cells expressing human MCH1R (hMCH1R) in a competition binding assay w...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50297044(CHEMBL557730 | N-(2-cyclopropylimidazo[1,2-a]pyrid...)
Affinity DataIC50:  5.60nMAssay Description:Displacement of [125I]MCH from human MCH1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM30156(2-aminobenzimidazole-based compound, 8)
Affinity DataIC50:  5.90nM EC50:  21nMpH: 7.4 T: 2°CAssay Description:Compounds were evaluated for their binding affinity to the membranes of CHO-K1 cells expressing human MCH1R (hMCH1R) in a competition binding assay w...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50297065(CHEMBL563096 | N-(2-cyclopropyl-3-methylimidazo[1,...)
Affinity DataIC50:  6nMAssay Description:Displacement of [125I]MCH from human MCH1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM30165(2-aminobenzimidazole-based compound, 13)
Affinity DataIC50:  6.70nM EC50:  27nMpH: 7.4 T: 2°CAssay Description:Compounds were evaluated for their binding affinity to the membranes of CHO-K1 cells expressing human MCH1R (hMCH1R) in a competition binding assay w...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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