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Found 91 with Last Name = 'murakata' and Initial = 'c'
TargetcAMP-dependent protein kinase(Oryctolagus cuniculus (Rabbit))
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM6760((+)-K-252a | CHEMBL281948 | K-252a | methyl (15S,1...)
Affinity DataIC50:  0.0160nMAssay Description:Inhibition of cAMP dependent Protein kinase A of rabbit Skeletal Muscle.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMyosin light chain kinase, smooth muscle(Gallus gallus (chicken))
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM6760((+)-K-252a | CHEMBL281948 | K-252a | methyl (15S,1...)
Affinity DataIC50:  0.0200nMAssay Description:Inhibition of Smooth muscle myosin light chain kinase of chicken gizzardMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM6760((+)-K-252a | CHEMBL281948 | K-252a | methyl (15S,1...)
Affinity DataIC50:  2.40nMAssay Description:Ability to inhibit human trk A tyrosine kinase expressed in baculovirus using ELISA based enzyme assay was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C alpha/beta/delta/epsilon/eta/gamma/theta/zeta type(Rattus norvegicus)
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50108296(CHEMBL289772 | Indolocarbazole analogue)
Affinity DataIC50:  3nMAssay Description:Binding affinity towards 5-hydroxytryptamine 3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-dependent protein kinase(Oryctolagus cuniculus (Rabbit))
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50058332(CHEMBL299496 | methyl 10,23-di(ethylsulfanylmethyl...)
Affinity DataIC50: >10nMAssay Description:Inhibition of cAMP dependent Protein kinase A of rabbit Skeletal Muscle.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMyosin light chain kinase, smooth muscle(Gallus gallus (chicken))
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50058332(CHEMBL299496 | methyl 10,23-di(ethylsulfanylmethyl...)
Affinity DataIC50: >10nMAssay Description:Inhibition of Smooth muscle myosin light chain kinase of chicken gizzardMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Rattus norvegicus)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50024270(CHEMBL85612)
Affinity DataIC50: <10nMAssay Description:Inhibition of v-Src tyrosine kinase autophosphorylation in SR3Y1 cells after 15 hr exposureMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase kinase kinase 11(Homo sapiens (Human))
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50108293(CHEMBL277817 | Indolocarbazole analogue)
Affinity DataIC50:  11nMAssay Description:Inhibition of Mixed lineage kinase 3 (MLK3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase kinase kinase 11(Homo sapiens (Human))
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50108295(CHEMBL288817 | Indolocarbazole analogue)
Affinity DataIC50:  11nMAssay Description:Inhibition of Mixed lineage kinase 3 (MLK3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase kinase kinase 11(Homo sapiens (Human))
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50108296(CHEMBL289772 | Indolocarbazole analogue)
Affinity DataIC50:  11nMAssay Description:Inhibition of Mixed lineage kinase 3 (MLK3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Rattus norvegicus)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50128843(16-Chloro-17,19-dihydroxy-4-methyl-3,7-dioxa-tricy...)
Affinity DataIC50:  13nMAssay Description:Inhibition of v-Src tyrosine kinase autophosphorylation in SR3Y1 cells after 15 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Rattus norvegicus)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50128852(2-(16-Chloro-17,19-dihydroxy-4-methyl-2-oxo-3,7-di...)
Affinity DataIC50:  14nMAssay Description:Inhibition of v-Src tyrosine kinase autophosphorylation in SR3Y1 cells after 15 hr exposureMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase kinase kinase 9(Homo sapiens (Human))
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50108296(CHEMBL289772 | Indolocarbazole analogue)
Affinity DataIC50:  15nMAssay Description:Inhibition of Mixed lineage kinase 1 (MLK1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase kinase kinase 9(Homo sapiens (Human))
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50108295(CHEMBL288817 | Indolocarbazole analogue)
Affinity DataIC50:  16nMAssay Description:Inhibition of Mixed lineage kinase 1 (MLK1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase kinase kinase 10(Homo sapiens (Human))
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50108295(CHEMBL288817 | Indolocarbazole analogue)
Affinity DataIC50:  16nMAssay Description:Inhibition of Mixed lineage kinase 2(MLK2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Rattus norvegicus)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50128851(2-(16-Chloro-17,19-dihydroxy-4-methyl-2-oxo-3,7-di...)
Affinity DataIC50:  17nMAssay Description:Inhibition of v-Src tyrosine kinase autophosphorylation in SR3Y1 cells after 15 hr exposureMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase kinase kinase 9(Homo sapiens (Human))
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50108293(CHEMBL277817 | Indolocarbazole analogue)
Affinity DataIC50:  19nMAssay Description:Inhibition of Mixed lineage kinase 1 (MLK1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase kinase kinase 10(Homo sapiens (Human))
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50108293(CHEMBL277817 | Indolocarbazole analogue)
Affinity DataIC50:  20nMAssay Description:Inhibition of Mixed lineage kinase 2(MLK2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase kinase kinase 11(Homo sapiens (Human))
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50108299(CHEMBL288229 | Indolocarbazole analogue)
Affinity DataIC50:  21nMAssay Description:Inhibition of Mixed lineage kinase 3 (MLK3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase kinase kinase 11(Homo sapiens (Human))
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM24942(CEP-1347 | CHEMBL290352 | methyl (15S,16R,18R)-10,...)
Affinity DataIC50:  23nMAssay Description:Inhibition of Mixed lineage kinase 3 (MLK3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Rattus norvegicus)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50128859(16-Chloro-17,19-dihydroxy-4-methyl-3,7-dioxa-tricy...)
Affinity DataIC50:  25nMAssay Description:Inhibition of v-Src tyrosine kinase autophosphorylation in SR3Y1 cells after 15 hr exposureMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase kinase kinase 10(Homo sapiens (Human))
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50108299(CHEMBL288229 | Indolocarbazole analogue)
Affinity DataIC50:  28nMAssay Description:Inhibition of Mixed lineage kinase 2(MLK2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase kinase kinase 9(Homo sapiens (Human))
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50108299(CHEMBL288229 | Indolocarbazole analogue)
Affinity DataIC50:  28nMAssay Description:Inhibition of Mixed lineage kinase 1 (MLK1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase kinase kinase 11(Homo sapiens (Human))
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50108297(CHEMBL288816 | Indolocarbazole analogue)
Affinity DataIC50:  31nMAssay Description:Inhibition of Mixed lineage kinase 3 (MLK3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase kinase kinase 9(Homo sapiens (Human))
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM24942(CEP-1347 | CHEMBL290352 | methyl (15S,16R,18R)-10,...)
Affinity DataIC50:  38nMAssay Description:Inhibition of Mixed lineage kinase 1 (MLK1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Rattus norvegicus)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50128846(2-(16-Chloro-17,19-dihydroxy-4-methyl-2-oxo-3,7-di...)
Affinity DataIC50:  43nMAssay Description:Inhibition of v-Src tyrosine kinase autophosphorylation in SR3Y1 cells after 15 hr exposureMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase kinase kinase 9(Homo sapiens (Human))
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50108291(CHEMBL36891 | Indolocarbazole analogue)
Affinity DataIC50:  43nMAssay Description:Inhibition of Mixed lineage kinase 1 (MLK1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
Kyowa Hakko Kirin

Curated by ChEMBL
LigandPNGBDBM50054109(CHEMBL3319301)
Affinity DataIC50:  44nMAssay Description:Inhibition of Eg5 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase kinase kinase 11(Homo sapiens (Human))
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50108291(CHEMBL36891 | Indolocarbazole analogue)
Affinity DataIC50:  44nMAssay Description:Inhibition of Mixed lineage kinase 3 (MLK3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase kinase kinase 9(Homo sapiens (Human))
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50108297(CHEMBL288816 | Indolocarbazole analogue)
Affinity DataIC50:  45nMAssay Description:Inhibition of Mixed lineage kinase 1 (MLK1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase kinase kinase 10(Homo sapiens (Human))
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM24942(CEP-1347 | CHEMBL290352 | methyl (15S,16R,18R)-10,...)
Affinity DataIC50:  51nMAssay Description:Inhibition of Mixed lineage kinase 2(MLK2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Rattus norvegicus)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50128850(2-(16-Chloro-17,19-dihydroxy-4-methyl-2-oxo-3,7-di...)
Affinity DataIC50:  54nMAssay Description:Inhibition of v-Src tyrosine kinase autophosphorylation in SR3Y1 cells after 15 hr exposureMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Rattus norvegicus)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50128847(10-Oxime radicicol | 16-Chloro-17,19-dihydroxy-4-m...)
Affinity DataIC50:  56nMAssay Description:Inhibition of v-Src tyrosine kinase autophosphorylation in SR3Y1 cells after 15 hr exposureMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase kinase kinase 11(Homo sapiens (Human))
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50108292(CHEMBL37529 | Indolocarbazole analogue)
Affinity DataIC50:  56nMAssay Description:Inhibition of Mixed lineage kinase 3 (MLK3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50108299(CHEMBL288229 | Indolocarbazole analogue)
Affinity DataIC50:  61nMAssay Description:Inhibition of NGF high affinity receptor tyrosine kinase TrkAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Rattus norvegicus)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50128857(16-Chloro-17,19-dihydroxy-4-methyl-3,7-dioxa-tricy...)
Affinity DataIC50:  67nMAssay Description:Inhibition of v-Src tyrosine kinase autophosphorylation in SR3Y1 cells after 15 hr exposureMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Rattus norvegicus)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50128853(16-Chloro-17,19-dihydroxy-4-methyl-3,7-dioxa-tricy...)
Affinity DataIC50:  70nMAssay Description:Inhibition of v-Src tyrosine kinase autophosphorylation in SR3Y1 cells after 15 hr exposureMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase kinase kinase 10(Homo sapiens (Human))
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50108297(CHEMBL288816 | Indolocarbazole analogue)
Affinity DataIC50:  89nMAssay Description:Inhibition of Mixed lineage kinase 2(MLK2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase kinase kinase 9(Homo sapiens (Human))
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50108292(CHEMBL37529 | Indolocarbazole analogue)
Affinity DataIC50:  90nMAssay Description:Inhibition of Mixed lineage kinase 1 (MLK1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase kinase kinase 11(Homo sapiens (Human))
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50108294(CHEMBL288818 | Indolocarbazole analogue)
Affinity DataIC50:  94nMAssay Description:Inhibition of Mixed lineage kinase 3 (MLK3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
Kyowa Hakko Kirin

Curated by ChEMBL
LigandPNGBDBM50054192(CHEMBL3319304)
Affinity DataIC50:  110nMAssay Description:Inhibition of Eg5 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
Kyowa Hakko Kirin

Curated by ChEMBL
LigandPNGBDBM50054192(CHEMBL3319304)
Affinity DataIC50:  110nMAssay Description:Inhibition of Eg5 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
Kyowa Hakko Kirin

Curated by ChEMBL
LigandPNGBDBM50054187(CHEMBL3319303)
Affinity DataIC50:  111nMAssay Description:Inhibition of Eg5 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
Kyowa Hakko Kirin

Curated by ChEMBL
LigandPNGBDBM50054187(CHEMBL3319303)
Affinity DataIC50:  111nMAssay Description:Inhibition of Eg5 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
Kyowa Hakko Kirin

Curated by ChEMBL
LigandPNGBDBM50054136(CHEMBL3319302)
Affinity DataIC50:  120nMAssay Description:Inhibition of Eg5 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase kinase kinase 11(Homo sapiens (Human))
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50108300(CHEMBL38338 | Indolocarbazole analogue)
Affinity DataIC50:  123nMAssay Description:Inhibition of Mixed lineage kinase 3 (MLK3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Rattus norvegicus)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50128845(16-Chloro-17,19-dihydroxy-4-methyl-3,7-dioxa-tricy...)
Affinity DataIC50:  140nMAssay Description:Inhibition of v-Src tyrosine kinase autophosphorylation in SR3Y1 cells after 15 hr exposureMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase kinase kinase 10(Homo sapiens (Human))
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50108291(CHEMBL36891 | Indolocarbazole analogue)
Affinity DataIC50:  140nMAssay Description:Inhibition of Mixed lineage kinase 2(MLK2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase kinase kinase 11(Homo sapiens (Human))
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50108298(CHEMBL29709 | Indolocarbazole analogue)
Affinity DataIC50:  143nMAssay Description:Inhibition of Mixed lineage kinase 3 (MLK3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase kinase kinase 9(Homo sapiens (Human))
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50108294(CHEMBL288818 | Indolocarbazole analogue)
Affinity DataIC50:  162nMAssay Description:Inhibition of Mixed lineage kinase 1 (MLK1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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